Viewing Study NCT01675427

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Ignite Creation Date: 2025-12-25 @ 5:11 AM
Ignite Modification Date: 2025-12-26 @ 4:16 AM
Study NCT ID: NCT01675427
Status: COMPLETED
Last Update Posted: 2015-08-26
First Post: 2012-08-24
Is NOT Gene Therapy: False
Has Adverse Events: True
Brief Title: A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C
Sponsor:
Organization:
Overview Dates Organization Conditions Design Enrollment Locations Outcomes Modules Raw JSON

Raw JSON

{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D019698', 'term': 'Hepatitis C, Chronic'}], 'ancestors': [{'id': 'D006526', 'term': 'Hepatitis C'}, {'id': 'D000086982', 'term': 'Blood-Borne Infections'}, {'id': 'D003141', 'term': 'Communicable Diseases'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D006525', 'term': 'Hepatitis, Viral, Human'}, {'id': 'D014777', 'term': 'Virus Diseases'}, {'id': 'D018178', 'term': 'Flaviviridae Infections'}, {'id': 'D012327', 'term': 'RNA Virus Infections'}, {'id': 'D006521', 'term': 'Hepatitis, Chronic'}, {'id': 'D006505', 'term': 'Hepatitis'}, {'id': 'D008107', 'term': 'Liver Diseases'}, {'id': 'D004066', 'term': 'Digestive System Diseases'}, {'id': 'D002908', 'term': 'Chronic Disease'}, {'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'genentech@druginfo.com', 'phone': '800-821-8590', 'title': 'Medical Communications', 'organization': 'Hoffmann-LaRoche'}, 'certainAgreement': {'otherDetails': "The Study being conducted under this Agreement is part of the Overall Study. Investigator is free to publish in reputable journals or to present at professional conferences the results of the Study, but only after the first publication or presentation that involves the Overall Study. The Sponsor may request that Confidential Information be deleted and/or the publication be postponed in order to protect the Sponsor's intellectual property rights.", 'restrictionType': 'OTHER', 'piSponsorEmployee': False, 'restrictiveAgreement': True}}, 'adverseEventsModule': {'timeFrame': 'Study Visit 1', 'description': 'Safety Population: Of the 4766 participants enrolled, 33 did not undergo blood sampling and were thus excluded from the safety analysis. Only serious adverse events caused by a protocol-mandated intervention during the single study visit (Study Visit 1) were assessed; nonserious adverse events were not documented in the course of the study.', 'eventGroups': [{'id': 'EG000', 'title': 'Participants With CHC', 'description': 'Both treatment-naive and treatment-experienced participants with CHC were enrolled in this prospective, interventional Phase 4 study.', 'otherNumAtRisk': 0, 'otherNumAffected': 0, 'seriousNumAtRisk': 4733, 'seriousNumAffected': 0}], 'frequencyThreshold': '0'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Number of Participants With Interleukin 28B (IL28B) Genotype rs12979860 by Cirrhosis Status and Hepatitis C Virus (HCV) Ribonucleic Acid (RNA) Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '976', 'groupId': 'OG000'}, {'value': '1511', 'groupId': 'OG001'}, {'value': '415', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 Cysteine-Cysteine (CC)', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 Threonine-Cysteine (TC)', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 Threonine-Threonine (TT)', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhosis (n=499,928,269)', 'categories': [{'measurements': [{'value': '111', 'groupId': 'OG000'}, {'value': '255', 'groupId': 'OG001'}, {'value': '87', 'groupId': 'OG002'}]}]}, {'title': 'G1, No cirrhosis (n=499,928,269)', 'categories': [{'measurements': [{'value': '388', 'groupId': 'OG000'}, {'value': '673', 'groupId': 'OG001'}, {'value': '182', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhosis (n=126,157,37)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, No cirrhosis (n=126,157,37)', 'categories': [{'measurements': [{'value': '103', 'groupId': 'OG000'}, {'value': '130', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhosis (n=231,276,65)', 'categories': [{'measurements': [{'value': '76', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G3, No cirrhosis (n=231,276,65)', 'categories': [{'measurements': [{'value': '155', 'groupId': 'OG000'}, {'value': '209', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhosis (n=92,129,38)', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '35', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, No cirrhosis (n=92,129,38)', 'categories': [{'measurements': [{'value': '63', 'groupId': 'OG000'}, {'value': '94', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhosis (n=28,21,6)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, No cirrhosis (n=28,21,6)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhosis (n=976,1511,415)', 'categories': [{'measurements': [{'value': '248', 'groupId': 'OG000'}, {'value': '390', 'groupId': 'OG001'}, {'value': '119', 'groupId': 'OG002'}]}]}, {'title': 'Total, No cirrhosis (n=976,1511,415)', 'categories': [{'measurements': [{'value': '728', 'groupId': 'OG000'}, {'value': '1121', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0018', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2289', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1112', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4681', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4828', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2702', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1 (single study visit)', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype (Genotype 1 \\[G1\\], Genotype 2 \\[G2\\], Genotype 3 \\[G3\\], Genotype 4 \\[G4\\], and all other genotypes \\[Other\\]) and cirrhosis status ('Cirrhosis/transition to cirrhosis' or 'No cirrhosis') were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive): Only participants who had not received prior treatment for CHC were included in the analysis; n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Cirrhosis Status and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '462', 'groupId': 'OG000'}, {'value': '850', 'groupId': 'OG001'}, {'value': '275', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhosis (n=281,653,226)', 'categories': [{'measurements': [{'value': '93', 'groupId': 'OG000'}, {'value': '208', 'groupId': 'OG001'}, {'value': '67', 'groupId': 'OG002'}]}]}, {'title': 'G1, No cirrhosis (n=281,653,226)', 'categories': [{'measurements': [{'value': '188', 'groupId': 'OG000'}, {'value': '445', 'groupId': 'OG001'}, {'value': '159', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhosis (n=89,36,9)', 'categories': [{'measurements': [{'value': '30', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, No cirrhosis (n=89,36,9)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '28', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhosis (n=55,75,19)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, No cirrhosis (n=55,75,19)', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhosis (n=25,66,19)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, No cirrhosis (n=25,66,19)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '51', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhosis (n=12,20,2)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, No cirrhosis (n=12,20,2)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhosis (n=462,850,275)', 'categories': [{'measurements': [{'value': '152', 'groupId': 'OG000'}, {'value': '264', 'groupId': 'OG001'}, {'value': '81', 'groupId': 'OG002'}]}]}, {'title': 'Total, No cirrhosis (n=462,850,275)', 'categories': [{'measurements': [{'value': '310', 'groupId': 'OG000'}, {'value': '586', 'groupId': 'OG001'}, {'value': '194', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.4133', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4400', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8597', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3975', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1781', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3159', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced): Only participants who had received prior treatment for CHC were included in the analysis; n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Cirrhosis Status and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1593', 'groupId': 'OG000'}, {'value': '1141', 'groupId': 'OG001'}, {'value': '168', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 Threonine-Glycine (TG)', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 Glycine-Glycine (GG)', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhosis (n=835,745,116)', 'categories': [{'measurements': [{'value': '200', 'groupId': 'OG000'}, {'value': '217', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'G1, No cirrhosis (n=835,745,116)', 'categories': [{'measurements': [{'value': '635', 'groupId': 'OG000'}, {'value': '528', 'groupId': 'OG001'}, {'value': '80', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhosis (n=197,111,12)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, No cirrhosis (n=197,111,12)', 'categories': [{'measurements': [{'value': '164', 'groupId': 'OG000'}, {'value': '92', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhosis (n=360,185,27)', 'categories': [{'measurements': [{'value': '111', 'groupId': 'OG000'}, {'value': '42', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, No cirrhosis (n=360,185,27)', 'categories': [{'measurements': [{'value': '249', 'groupId': 'OG000'}, {'value': '143', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhosis (n=164,85,10)', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, No cirrhosis (n=164,85,10)', 'categories': [{'measurements': [{'value': '119', 'groupId': 'OG000'}, {'value': '59', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhosis (n=37,15,3)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, No cirrhosis (n=37,15,3)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhosis (n=1593,1141,168)', 'categories': [{'measurements': [{'value': '400', 'groupId': 'OG000'}, {'value': '309', 'groupId': 'OG001'}, {'value': '48', 'groupId': 'OG002'}]}]}, {'title': 'Total, No cirrhosis (n=1593,1141,168)', 'categories': [{'measurements': [{'value': '1193', 'groupId': 'OG000'}, {'value': '832', 'groupId': 'OG001'}, {'value': '120', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0126', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7174', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1380', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6258', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5751', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1681', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Cirrhosis Status and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '796', 'groupId': 'OG000'}, {'value': '682', 'groupId': 'OG001'}, {'value': '109', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhosis (n=528,539,93)', 'categories': [{'measurements': [{'value': '158', 'groupId': 'OG000'}, {'value': '179', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'G1, No cirrhosis (n=528,539,93)', 'categories': [{'measurements': [{'value': '370', 'groupId': 'OG000'}, {'value': '360', 'groupId': 'OG001'}, {'value': '62', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhosis (n=102,25,7)', 'categories': [{'measurements': [{'value': '35', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, No cirrhosis (n=102,25,7)', 'categories': [{'measurements': [{'value': '67', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhosis (n=81,59,9)', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, No cirrhosis (n=81,59,9)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhosis (n=70,40,0)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, No cirrhosis (n=70,40,0)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhosis (n=15,19,0)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, No cirrhosis (n=15,19,0)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhosis (n=796,682,109)', 'categories': [{'measurements': [{'value': '241', 'groupId': 'OG000'}, {'value': '219', 'groupId': 'OG001'}, {'value': '37', 'groupId': 'OG002'}]}]}, {'title': 'Total, No cirrhosis (n=796,682,109)', 'categories': [{'measurements': [{'value': '555', 'groupId': 'OG000'}, {'value': '463', 'groupId': 'OG001'}, {'value': '72', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.2693', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3240', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7006', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0403', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1075', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3295', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '127', 'groupId': 'OG000'}, {'value': '184', 'groupId': 'OG001'}, {'value': '61', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Grade A0 (n=76,132,46)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A1 (n=76,132,46)', 'categories': [{'measurements': [{'value': '38', 'groupId': 'OG000'}, {'value': '54', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A2 (n=76,132,46)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '57', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A3 (n=76,132,46)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A0 (n=8,4,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A1 (n=8,4,0)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A2 (n=8,4,0)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A3 (n=8,4,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A0 (n=18,14,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A1 (n=18,14,5)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A2 (n=18,14,5)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A3 (n=18,14,5)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A0 (n=21,34,8)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A1 (n=21,34,8)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A2 (n=21,34,8)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A3 (n=21,34,8)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A0 (n=4,0,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A1 (n=4,0,2)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A2 (n=4,0,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A3 (n=4,0,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A0 (n=127,184,61)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A1 (n=127,184,61)', 'categories': [{'measurements': [{'value': '64', 'groupId': 'OG000'}, {'value': '84', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A2 (n=127,184,61)', 'categories': [{'measurements': [{'value': '46', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A3 (n=127,184,61)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.9859', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7055', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0920', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0781', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4795', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3069', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '149', 'groupId': 'OG000'}, {'value': '249', 'groupId': 'OG001'}, {'value': '73', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Grade A0 (n=102,203,60)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A1 (n=102,203,60)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '79', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A2 (n=102,203,60)', 'categories': [{'measurements': [{'value': '48', 'groupId': 'OG000'}, {'value': '90', 'groupId': 'OG001'}, {'value': '32', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A3 (n=102,203,60)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A0 (n=28,7,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A1 (n=28,7,1)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A2 (n=28,7,1)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A3 (n=28,7,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A0 (n=11,7,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A1 (n=11,7,4)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A2 (n=11,7,4)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A3 (n=11,7,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A0 (n=5,29,8)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A1 (n=5,29,8)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A2 (n=5,29,8)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A3 (n=5,29,8)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A0 (n=3,3,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A1 (n=3,3,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A2 (n=3,3,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A3 (n=3,3,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A0 (n=149,249,73)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A1 (n=149,249,73)', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '103', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A2 (n=149,249,73)', 'categories': [{'measurements': [{'value': '72', 'groupId': 'OG000'}, {'value': '106', 'groupId': 'OG001'}, {'value': '38', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A3 (n=149,249,73)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '34', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.5216', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3419', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7586', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1351', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2386', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3921', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '207', 'groupId': 'OG000'}, {'value': '143', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Grade A0 (n=127,109,18)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A1 (n=127,109,18)', 'categories': [{'measurements': [{'value': '63', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A2 (n=127,109,18)', 'categories': [{'measurements': [{'value': '46', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A3 (n=127,109,18)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A0 (n=11,1,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A1 (n=11,1,0)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A2 (n=11,1,0)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A3 (n=11,1,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A0 (n=22,13,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A1 (n=22,13,2)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A2 (n=22,13,2)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A3 (n=22,13,2)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A0 (n=43,19,1)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A1 (n=43,19,1)', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A2 (n=43,19,1)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A3 (n=43,19,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A0 (n=4,1,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A1 (n=4,1,1)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A2 (n=4,1,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A3 (n=4,1,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A0 (n=207,143,22)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A1 (n=207,143,22)', 'categories': [{'measurements': [{'value': '109', 'groupId': 'OG000'}, {'value': '64', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A2 (n=207,143,22)', 'categories': [{'measurements': [{'value': '69', 'groupId': 'OG000'}, {'value': '52', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A3 (n=207,143,22)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.8537', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0763', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2432', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4247', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4884', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6119', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '235', 'groupId': 'OG000'}, {'value': '205', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Grade A0 (n=160,177,28)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A1 (n=160,177,28)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '70', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A2 (n=160,177,28)', 'categories': [{'measurements': [{'value': '77', 'groupId': 'OG000'}, {'value': '79', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Grade A3 (n=160,177,28)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A0 (n=30,5,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A1 (n=30,5,1)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A2 (n=30,5,1)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Grade A3 (n=30,5,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A0 (n=14,6,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A1 (n=14,6,2)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A2 (n=14,6,2)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Grade A3 (n=14,6,2)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A0 (n=28,14,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A1 (n=28,14,0)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A2 (n=28,14,0)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Grade A3 (n=28,14,0)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A0 (n=3,3,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A1 (n=3,3,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A2 (n=3,3,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Grade A3 (n=3,3,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A0 (n=235,205,31)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A1 (n=235,205,31)', 'categories': [{'measurements': [{'value': '85', 'groupId': 'OG000'}, {'value': '85', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A2 (n=235,205,31)', 'categories': [{'measurements': [{'value': '110', 'groupId': 'OG000'}, {'value': '90', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'Total, Grade A3 (n=235,205,31)', 'categories': [{'measurements': [{'value': '35', 'groupId': 'OG000'}, {'value': '24', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.2416', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2671', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4619', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8364', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2386', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2887', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Gender: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '978', 'groupId': 'OG000'}, {'value': '1518', 'groupId': 'OG001'}, {'value': '420', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'Male', 'categories': [{'measurements': [{'value': '582', 'groupId': 'OG000'}, {'value': '802', 'groupId': 'OG001'}, {'value': '224', 'groupId': 'OG002'}]}]}, {'title': 'Female', 'categories': [{'measurements': [{'value': '396', 'groupId': 'OG000'}, {'value': '716', 'groupId': 'OG001'}, {'value': '196', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0049', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including gender, were obtained from medical records and/or participant interview at the Study Visit.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Gender: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '490', 'groupId': 'OG000'}, {'value': '914', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'Male', 'categories': [{'measurements': [{'value': '287', 'groupId': 'OG000'}, {'value': '509', 'groupId': 'OG001'}, {'value': '169', 'groupId': 'OG002'}]}]}, {'title': 'Female', 'categories': [{'measurements': [{'value': '203', 'groupId': 'OG000'}, {'value': '405', 'groupId': 'OG001'}, {'value': '127', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.5651', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. 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Demographic characteristics, including height and pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. 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HCV RNA genotype was obtained from medical records.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '476', 'groupId': 'OG000'}, {'value': '892', 'groupId': 'OG001'}, {'value': '291', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1', 'categories': [{'measurements': [{'value': '295', 'groupId': 'OG000'}, {'value': '703', 'groupId': 'OG001'}, {'value': '239', 'groupId': 'OG002'}]}]}, {'title': 'G2', 'categories': [{'measurements': [{'value': '92', 'groupId': 'OG000'}, {'value': '38', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G3', 'categories': [{'measurements': [{'value': '63', 'groupId': 'OG000'}, {'value': '84', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'G4', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. 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HCV RNA genotype was obtained from medical records.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '834', 'groupId': 'OG000'}, {'value': '709', 'groupId': 'OG001'}, {'value': '116', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1', 'categories': [{'measurements': [{'value': '563', 'groupId': 'OG000'}, {'value': '574', 'groupId': 'OG001'}, {'value': '100', 'groupId': 'OG002'}]}]}, {'title': 'G2', 'categories': [{'measurements': [{'value': '107', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G3', 'categories': [{'measurements': [{'value': '93', 'groupId': 'OG000'}, {'value': '65', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G4', 'categories': [{'measurements': [{'value': '71', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. 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HCV RNA level was obtained from medical records. 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[{'measurements': [{'value': '5.97', 'groupId': 'OG000', 'lowerLimit': '5.64', 'upperLimit': '6.30'}, {'value': '5.78', 'groupId': 'OG001', 'lowerLimit': '5.52', 'upperLimit': '6.05'}, {'value': '5.60', 'groupId': 'OG002', 'lowerLimit': '5.15', 'upperLimit': '6.04'}]}]}, {'title': 'G4 (n=22,56,20)', 'categories': [{'measurements': [{'value': '5.49', 'groupId': 'OG000', 'lowerLimit': '5.12', 'upperLimit': '5.87'}, {'value': '5.58', 'groupId': 'OG001', 'lowerLimit': '5.39', 'upperLimit': '5.77'}, {'value': '5.66', 'groupId': 'OG002', 'lowerLimit': '5.31', 'upperLimit': '6.00'}]}]}, {'title': 'Other (n=10,14,2)', 'categories': [{'measurements': [{'value': '5.59', 'groupId': 'OG000', 'lowerLimit': '4.57', 'upperLimit': '6.61'}, {'value': '5.63', 'groupId': 'OG001', 'lowerLimit': '5.17', 'upperLimit': '6.10'}, {'value': '4.90', 'groupId': 'OG002', 'lowerLimit': '4.50', 'upperLimit': '5.30'}]}]}, {'title': 'Total (n=382,744,240)', 'categories': [{'measurements': [{'value': '5.89', 'groupId': 'OG000', 'lowerLimit': '5.79', 'upperLimit': '5.98'}, {'value': '5.93', 'groupId': 'OG001', 'lowerLimit': '5.88', 'upperLimit': '5.98'}, {'value': '5.80', 'groupId': 'OG002', 'lowerLimit': '5.71', 'upperLimit': '5.88'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0145', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1027', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5998', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2935', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0039', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.', 'unitOfMeasure': 'log10 IU/mL', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '331', 'groupId': 'OG000'}, {'value': '465', 'groupId': 'OG001'}, {'value': '126', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhotic (n=207,324,91)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Transition (n=207,324,91)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Advanced (n=207,324,91)', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '88', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mild (n=207,324,91)', 'categories': [{'measurements': [{'value': '101', 'groupId': 'OG000'}, {'value': '140', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'G1, No fibrosis (n=207,324,91)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhotic (n=24,25,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Transition (n=24,25,5)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Advanced (n=24,25,5)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mild (n=24,25,5)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, No fibrosis (n=24,25,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhotic (n=67,65,16)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Transition (n=67,65,16)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Advanced (n=67,65,16)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mild (n=67,65,16)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, No fibrosis (n=67,65,16)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhotic (n=28,48,12)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Transition (n=28,48,12)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Advanced (n=28,48,12)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mild (n=28,48,12)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G4, No fibrosis (n=28,48,12)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhotic (n=5,3,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Transition (n=5,3,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Advanced (n=5,3,2)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mild (n=5,3,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, No fibrosis (n=5,3,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhotic (n=331,465,126)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '25', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Transition (n=331,465,126)', 'categories': [{'measurements': [{'value': '48', 'groupId': 'OG000'}, {'value': '52', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'Total, Advanced (n=331,465,126)', 'categories': [{'measurements': [{'value': '81', 'groupId': 'OG000'}, {'value': '119', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mild (n=331,465,126)', 'categories': [{'measurements': [{'value': '155', 'groupId': 'OG000'}, {'value': '208', 'groupId': 'OG001'}, {'value': '51', 'groupId': 'OG002'}]}]}, {'title': 'Total, No fibrosis (n=331,465,126)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '61', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.1981', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1616', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1192', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4485', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1525', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7262', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '277', 'groupId': 'OG000'}, {'value': '511', 'groupId': 'OG001'}, {'value': '164', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhotic (n=186,422,141)', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G1, Transition (n=186,422,141)', 'categories': [{'measurements': [{'value': '35', 'groupId': 'OG000'}, {'value': '86', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'G1, Advanced (n=186,422,141)', 'categories': [{'measurements': [{'value': '63', 'groupId': 'OG000'}, {'value': '111', 'groupId': 'OG001'}, {'value': '40', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mild (n=186,422,141)', 'categories': [{'measurements': [{'value': '55', 'groupId': 'OG000'}, {'value': '141', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'G1, No fibrosis (n=186,422,141)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhotic (n=49,11,5)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Transition (n=49,11,5)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Advanced (n=49,11,5)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mild (n=49,11,5)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, No fibrosis (n=49,11,5)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhotic (n=26,31,7)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Transition (n=26,31,7)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Advanced (n=26,31,7)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mild (n=26,31,7)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, No fibrosis (n=26,31,7)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhotic (n=9,35,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Transition (n=9,35,10)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Advanced (n=9,35,10)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mild (n=9,35,10)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, No fibrosis (n=9,35,10)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhotic (n=7,12,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Transition (n=7,12,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Advanced (n=7,12,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mild (n=7,12,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, No fibrosis (n=7,12,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhotic (n=277,511,164)', 'categories': [{'measurements': [{'value': '32', 'groupId': 'OG000'}, {'value': '54', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Transition (n=277,511,164)', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '96', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}, {'title': 'Total, Advanced (n=277,511,164)', 'categories': [{'measurements': [{'value': '88', 'groupId': 'OG000'}, {'value': '140', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mild (n=277,511,164)', 'categories': [{'measurements': [{'value': '84', 'groupId': 'OG000'}, {'value': '173', 'groupId': 'OG001'}, {'value': '57', 'groupId': 'OG002'}]}]}, {'title': 'Total, No fibrosis (n=277,511,164)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '48', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0911', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4674', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1604', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5937', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3830', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0507', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '527', 'groupId': 'OG000'}, {'value': '343', 'groupId': 'OG001'}, {'value': '52', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhotic (n=331,252,39)', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Transition (n=331,252,39)', 'categories': [{'measurements': [{'value': '44', 'groupId': 'OG000'}, {'value': '34', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Advanced (n=331,252,39)', 'categories': [{'measurements': [{'value': '89', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mild (n=331,252,39)', 'categories': [{'measurements': [{'value': '145', 'groupId': 'OG000'}, {'value': '110', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'G1, No fibrosis (n=331,252,39)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhotic (n=33,19,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Transition (n=33,19,2)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Advanced (n=33,19,2)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mild (n=33,19,2)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, No fibrosis (n=33,19,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhotic (n=98,42,8)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Transition (n=98,42,8)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Advanced (n=98,42,8)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mild (n=98,42,8)', 'categories': [{'measurements': [{'value': '40', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, No fibrosis (n=98,42,8)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhotic (n=59,27,2)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Transition (n=59,27,2)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Advanced (n=59,27,2)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mild (n=59,27,2)', 'categories': [{'measurements': [{'value': '32', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, No fibrosis (n=59,27,2)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhotic (n=6,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Transition (n=6,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Advanced (n=6,3,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mild (n=6,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, No fibrosis (n=6,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhotic (n=527,343,52)', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Transition (n=527,343,52)', 'categories': [{'measurements': [{'value': '70', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'Total, Advanced (n=527,343,52)', 'categories': [{'measurements': [{'value': '133', 'groupId': 'OG000'}, {'value': '83', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mild (n=527,343,52)', 'categories': [{'measurements': [{'value': '235', 'groupId': 'OG000'}, {'value': '155', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'Total, No fibrosis (n=527,343,52)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '44', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.8686', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3135', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0578', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5833', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1610', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2925', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '468', 'groupId': 'OG000'}, {'value': '415', 'groupId': 'OG001'}, {'value': '69', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Cirrhotic (n=332,356,61)', 'categories': [{'measurements': [{'value': '34', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Transition (n=332,356,61)', 'categories': [{'measurements': [{'value': '58', 'groupId': 'OG000'}, {'value': '74', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Advanced (n=332,356,61)', 'categories': [{'measurements': [{'value': '109', 'groupId': 'OG000'}, {'value': '92', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mild (n=332,356,61)', 'categories': [{'measurements': [{'value': '106', 'groupId': 'OG000'}, {'value': '119', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G1, No fibrosis (n=332,356,61)', 'categories': [{'measurements': [{'value': '25', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G2, Cirrhotic (n=52,9,4)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Transition (n=52,9,4)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Advanced (n=52,9,4)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mild (n=52,9,4)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, No fibrosis (n=52,9,4)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Cirrhotic (n=38,22,4)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Transition (n=38,22,4)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Advanced (n=38,22,4)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mild (n=38,22,4)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, No fibrosis (n=38,22,4)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Cirrhotic (n=37,17,0)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Transition (n=37,17,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Advanced (n=37,17,0)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mild (n=37,17,0)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, No fibrosis (n=37,17,0)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Cirrhotic (n=9,11,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Transition (n=9,11,0)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Advanced (n=9,11,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mild (n=9,11,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, No fibrosis (n=9,11,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Cirrhotic (n=468,415,69)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Transition (n=468,415,69)', 'categories': [{'measurements': [{'value': '78', 'groupId': 'OG000'}, {'value': '80', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, Advanced (n=468,415,69)', 'categories': [{'measurements': [{'value': '152', 'groupId': 'OG000'}, {'value': '108', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mild (n=468,415,69)', 'categories': [{'measurements': [{'value': '147', 'groupId': 'OG000'}, {'value': '145', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'Total, No fibrosis (n=468,415,69)', 'categories': [{'measurements': [{'value': '39', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.3709', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2054', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8457', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3492', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2846', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2646', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '166', 'groupId': 'OG000'}, {'value': '249', 'groupId': 'OG001'}, {'value': '77', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Stage F0 (n=95,177,56)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F1 (n=95,177,56)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F2 (n=95,177,56)', 'categories': [{'measurements': [{'value': '34', 'groupId': 'OG000'}, {'value': '57', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F3 (n=95,177,56)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F4 (n=95,177,56)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F0 (n=15,11,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F1 (n=15,11,2)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F2 (n=15,11,2)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F3 (n=15,11,2)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F4 (n=15,11,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F0 (n=31,26,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F1 (n=31,26,9)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F2 (n=31,26,9)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F3 (n=31,26,9)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F4 (n=31,26,9)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F0 (n=21,35,8)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F1 (n=21,35,8)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F2 (n=21,35,8)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F3 (n=21,35,8)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F4 (n=21,35,8)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F0 (n=4,0,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F1 (n=4,0,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F2 (n=4,0,2)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F3 (n=4,0,2)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F4 (n=4,0,2)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F0 (n=166,249,77)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F1 (n=166,249,77)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '90', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F2 (n=166,249,77)', 'categories': [{'measurements': [{'value': '55', 'groupId': 'OG000'}, {'value': '79', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F3 (n=166,249,77)', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F4 (n=166,249,77)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.5348', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5469', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0463', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9393', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3404', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4237', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '174', 'groupId': 'OG000'}, {'value': '322', 'groupId': 'OG001'}, {'value': '86', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Stage F0 (n=119,259,70)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F1 (n=119,259,70)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '61', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F2 (n=119,259,70)', 'categories': [{'measurements': [{'value': '44', 'groupId': 'OG000'}, {'value': '83', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F3 (n=119,259,70)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F4 (n=119,259,70)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F0 (n=31,7,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F1 (n=31,7,1)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F2 (n=31,7,1)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F3 (n=31,7,1)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F4 (n=31,7,1)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F0 (n=16,23,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F1 (n=16,23,5)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F2 (n=16,23,5)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F3 (n=16,23,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F4 (n=16,23,5)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F0 (n=5,30,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F1 (n=5,30,9)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F2 (n=5,30,9)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F3 (n=5,30,9)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F4 (n=5,30,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F0 (n=3,3,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F1 (n=3,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F2 (n=3,3,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F3 (n=3,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F4 (n=3,3,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F0 (n=174,322,86)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F1 (n=174,322,86)', 'categories': [{'measurements': [{'value': '44', 'groupId': 'OG000'}, {'value': '80', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F2 (n=174,322,86)', 'categories': [{'measurements': [{'value': '61', 'groupId': 'OG000'}, {'value': '108', 'groupId': 'OG001'}, {'value': '37', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F3 (n=174,322,86)', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F4 (n=174,322,86)', 'categories': [{'measurements': [{'value': '24', 'groupId': 'OG000'}, {'value': '44', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.2510', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2943', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0478', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5387', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3878', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0748', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '277', 'groupId': 'OG000'}, {'value': '187', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Stage F0 (n=168,139,21)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F1 (n=168,139,21)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F2 (n=168,139,21)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F3 (n=168,139,21)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F4 (n=168,139,21)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F0 (n=20,7,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F1 (n=20,7,1)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F2 (n=20,7,1)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F3 (n=20,7,1)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F4 (n=20,7,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F0 (n=42,20,4)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F1 (n=42,20,4)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F2 (n=42,20,4)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F3 (n=42,20,4)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F4 (n=42,20,4)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F0 (n=43,20,1)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F1 (n=43,20,1)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F2 (n=43,20,1)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F3 (n=43,20,1)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F4 (n=43,20,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F0 (n=4,1,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F1 (n=4,1,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F2 (n=4,1,1)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F3 (n=4,1,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F4 (n=4,1,1)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F0 (n=277,187,28)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F1 (n=277,187,28)', 'categories': [{'measurements': [{'value': '101', 'groupId': 'OG000'}, {'value': '64', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F2 (n=277,187,28)', 'categories': [{'measurements': [{'value': '89', 'groupId': 'OG000'}, {'value': '57', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F3 (n=277,187,28)', 'categories': [{'measurements': [{'value': '39', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F4 (n=277,187,28)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.9887', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5507', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0175', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2246', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3519', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7140', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '291', 'groupId': 'OG000'}, {'value': '256', 'groupId': 'OG001'}, {'value': '35', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Stage F0 (n=200,217,31)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F1 (n=200,217,31)', 'categories': [{'measurements': [{'value': '46', 'groupId': 'OG000'}, {'value': '50', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F2 (n=200,217,31)', 'categories': [{'measurements': [{'value': '74', 'groupId': 'OG000'}, {'value': '74', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F3 (n=200,217,31)', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '48', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Stage F4 (n=200,217,31)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F0 (n=33,5,1)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F1 (n=33,5,1)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F2 (n=33,5,1)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F3 (n=33,5,1)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Stage F4 (n=33,5,1)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F0 (n=25,16,3)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F1 (n=25,16,3)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F2 (n=25,16,3)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F3 (n=25,16,3)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Stage F4 (n=25,16,3)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F0 (n=30,14,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F1 (n=30,14,0)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F2 (n=30,14,0)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F3 (n=30,14,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Stage F4 (n=30,14,0)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F0 (n=3,4,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F1 (n=3,4,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F2 (n=3,4,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F3 (n=3,4,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Stage F4 (n=3,4,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F0 (n=291,256,35)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F1 (n=291,256,35)', 'categories': [{'measurements': [{'value': '72', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F2 (n=291,256,35)', 'categories': [{'measurements': [{'value': '107', 'groupId': 'OG000'}, {'value': '88', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F3 (n=291,256,35)', 'categories': [{'measurements': [{'value': '57', 'groupId': 'OG000'}, {'value': '51', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Stage F4 (n=291,256,35)', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '35', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.8622', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1622', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2566', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1574', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5784', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6603', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Mean FibroScan Values by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '324', 'groupId': 'OG000'}, {'value': '517', 'groupId': 'OG001'}, {'value': '140', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=177,316,82)', 'categories': [{'measurements': [{'value': '9.61', 'groupId': 'OG000', 'lowerLimit': '8.51', 'upperLimit': '10.7'}, {'value': '10.2', 'groupId': 'OG001', 'lowerLimit': '9.22', 'upperLimit': '11.1'}, {'value': '12.6', 'groupId': 'OG002', 'lowerLimit': '10.3', 'upperLimit': '15.0'}]}]}, {'title': 'G2 (n=40,55,15)', 'categories': [{'measurements': [{'value': '11.1', 'groupId': 'OG000', 'lowerLimit': '7.26', 'upperLimit': '14.9'}, {'value': '7.69', 'groupId': 'OG001', 'lowerLimit': '6.65', 'upperLimit': '8.72'}, {'value': '7.15', 'groupId': 'OG002', 'lowerLimit': '4.35', 'upperLimit': '9.94'}]}]}, {'title': 'G3 (n=60,83,24)', 'categories': [{'measurements': [{'value': '11.7', 'groupId': 'OG000', 'lowerLimit': '9.45', 'upperLimit': '14.0'}, {'value': '9.3', 'groupId': 'OG001', 'lowerLimit': '7.82', 'upperLimit': '10.8'}, {'value': '8.99', 'groupId': 'OG002', 'lowerLimit': '6.14', 'upperLimit': '11.8'}]}]}, {'title': 'G4 (n=43,59,18)', 'categories': [{'measurements': [{'value': '11.4', 'groupId': 'OG000', 'lowerLimit': '7.54', 'upperLimit': '15.3'}, {'value': '13.4', 'groupId': 'OG001', 'lowerLimit': '10.4', 'upperLimit': '16.5'}, {'value': '11.1', 'groupId': 'OG002', 'lowerLimit': '5.85', 'upperLimit': '16.4'}]}]}, {'title': 'Other (n=4,4,1)', 'categories': [{'measurements': [{'value': '12.1', 'groupId': 'OG000', 'lowerLimit': '4.65', 'upperLimit': '19.6'}, {'value': '21.9', 'groupId': 'OG001', 'lowerLimit': '-34.4', 'upperLimit': '78.2'}, {'value': '4.00', 'comment': 'Confidence interval not presented because the analysis only included 1 participant.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=324,517,140)', 'categories': [{'measurements': [{'value': '10.5', 'groupId': 'OG000', 'lowerLimit': '9.45', 'upperLimit': '11.4'}, {'value': '10.2', 'groupId': 'OG001', 'lowerLimit': '9.46', 'upperLimit': '11.0'}, {'value': '11.2', 'groupId': 'OG002', 'lowerLimit': '9.53', 'upperLimit': '12.8'}]}]}], 'analyses': [{'pValue': '0.0605', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0899', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0634', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6165', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1649', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9159', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kilopascals (kPa).', 'unitOfMeasure': 'kPa', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Mean FibroScan Values by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '54', 'groupId': 'OG000'}, {'value': '122', 'groupId': 'OG001'}, {'value': '39', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=27,84,32)', 'categories': [{'measurements': [{'value': '11.7', 'groupId': 'OG000', 'lowerLimit': '8.4', 'upperLimit': '14.9'}, {'value': '13.2', 'groupId': 'OG001', 'lowerLimit': '10.3', 'upperLimit': '16.2'}, {'value': '13.5', 'groupId': 'OG002', 'lowerLimit': '9.69', 'upperLimit': '17.4'}]}]}, {'title': 'G2 (n=6,10,0)', 'categories': [{'measurements': [{'value': '13.3', 'groupId': 'OG000', 'lowerLimit': '6.37', 'upperLimit': '20.2'}, {'value': '5.11', 'groupId': 'OG001', 'lowerLimit': '4.06', 'upperLimit': '6.16'}, {'value': '8.17', 'groupId': 'OG002', 'lowerLimit': '5.14', 'upperLimit': '11.2'}]}]}, {'title': 'G3 (n=15,14,4)', 'categories': [{'measurements': [{'value': '12.3', 'groupId': 'OG000', 'lowerLimit': '6.57', 'upperLimit': '18.1'}, {'value': '8.64', 'groupId': 'OG001', 'lowerLimit': '5.22', 'upperLimit': '12.1'}, {'value': '9.48', 'groupId': 'OG002', 'lowerLimit': '0.708', 'upperLimit': '18.2'}]}]}, {'title': 'G4 (n=6,14,3)', 'categories': [{'measurements': [{'value': '10.7', 'groupId': 'OG000', 'lowerLimit': '-2.17', 'upperLimit': '23.5'}, {'value': '10.6', 'groupId': 'OG001', 'lowerLimit': '6.16', 'upperLimit': '15.0'}, {'value': '8.9', 'groupId': 'OG002', 'lowerLimit': '-0.589', 'upperLimit': '18.4'}]}]}, {'title': 'Other (n=0,0,0)', 'categories': [{'measurements': [{'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG000', 'lowerLimit': 'NA', 'upperLimit': 'NA'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG001', 'lowerLimit': 'NA', 'upperLimit': 'NA'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=54,122,39)', 'categories': [{'measurements': [{'value': '11.9', 'groupId': 'OG000', 'lowerLimit': '9.46', 'upperLimit': '14.4'}, {'value': '11.7', 'groupId': 'OG001', 'lowerLimit': '9.61', 'upperLimit': '13.9'}, {'value': '12.8', 'groupId': 'OG002', 'lowerLimit': '9.54', 'upperLimit': '16.0'}]}]}], 'analyses': [{'pValue': '0.7454', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0016', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5261', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3422', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9026', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.', 'unitOfMeasure': 'kPa', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Mean FibroScan Values by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '528', 'groupId': 'OG000'}, {'value': '404', 'groupId': 'OG001'}, {'value': '49', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=287,259,29)', 'categories': [{'measurements': [{'value': '9.46', 'groupId': 'OG000', 'lowerLimit': '8.61', 'upperLimit': '10.3'}, {'value': '10.9', 'groupId': 'OG001', 'lowerLimit': '9.78', 'upperLimit': '12.1'}, {'value': '13.7', 'groupId': 'OG002', 'lowerLimit': '9.77', 'upperLimit': '17.6'}]}]}, {'title': 'G2 (n=63,42,5)', 'categories': [{'measurements': [{'value': '9.44', 'groupId': 'OG000', 'lowerLimit': '6.96', 'upperLimit': '11.9'}, {'value': '7.95', 'groupId': 'OG001', 'lowerLimit': '6.73', 'upperLimit': '9.18'}, {'value': '8.76', 'groupId': 'OG002', 'lowerLimit': '-1.92', 'upperLimit': '19.4'}]}]}, {'title': 'G3 (n=100,57,10)', 'categories': [{'measurements': [{'value': '11.4', 'groupId': 'OG000', 'lowerLimit': '9.67', 'upperLimit': '13.2'}, {'value': '8.45', 'groupId': 'OG001', 'lowerLimit': '7.30', 'upperLimit': '9.60'}, {'value': '6.51', 'groupId': 'OG002', 'lowerLimit': '2.86', 'upperLimit': '10.2'}]}]}, {'title': 'G4 (n=72,44,4)', 'categories': [{'measurements': [{'value': '11.2', 'groupId': 'OG000', 'lowerLimit': '8.63', 'upperLimit': '13.8'}, {'value': '14.2', 'groupId': 'OG001', 'lowerLimit': '10.2', 'upperLimit': '18.2'}, {'value': '13.7', 'groupId': 'OG002', 'lowerLimit': '-9.32', 'upperLimit': '36.6'}]}]}, {'title': 'Other (n=6,2,1)', 'categories': [{'measurements': [{'value': '9.32', 'groupId': 'OG000', 'lowerLimit': '3.40', 'upperLimit': '15.2'}, {'value': '40.1', 'groupId': 'OG001', 'lowerLimit': '-403', 'upperLimit': '484'}, {'value': '4.00', 'comment': 'Confidence interval not presented because the analysis only included 1 participant.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=528,404,49)', 'categories': [{'measurements': [{'value': '10.1', 'groupId': 'OG000', 'lowerLimit': '9.34', 'upperLimit': '10.8'}, {'value': '10.8', 'groupId': 'OG001', 'lowerLimit': '9.83', 'upperLimit': '11.7'}, {'value': '11.5', 'groupId': 'OG002', 'lowerLimit': '8.70', 'upperLimit': '14.3'}]}]}], 'analyses': [{'pValue': '0.0017', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8864', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0291', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5472', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '1.000', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1148', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.', 'unitOfMeasure': 'kPa', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'PRIMARY', 'title': 'Mean FibroScan Values by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '97', 'groupId': 'OG000'}, {'value': '103', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=53,77,13)', 'categories': [{'measurements': [{'value': '12.7', 'groupId': 'OG000', 'lowerLimit': '9.89', 'upperLimit': '15.5'}, {'value': '13.7', 'groupId': 'OG001', 'lowerLimit': '10.6', 'upperLimit': '16.9'}, {'value': '10.2', 'groupId': 'OG002', 'lowerLimit': '7.00', 'upperLimit': '13.4'}]}]}, {'title': 'G2 (n=9,7,0)', 'categories': [{'measurements': [{'value': '10.5', 'groupId': 'OG000', 'lowerLimit': '5.31', 'upperLimit': '15.6'}, {'value': '5.21', 'groupId': 'OG001', 'lowerLimit': '3.71', 'upperLimit': '6.72'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'G3 (n=21,10,2)', 'categories': [{'measurements': [{'value': '12.1', 'groupId': 'OG000', 'lowerLimit': '7.70', 'upperLimit': '16.4'}, {'value': '7.82', 'groupId': 'OG001', 'lowerLimit': '5.00', 'upperLimit': '10.6'}, {'value': '5.95', 'groupId': 'OG002', 'lowerLimit': '-8.66', 'upperLimit': '20.6'}]}]}, {'title': 'G4 (n=14,9,0)', 'categories': [{'measurements': [{'value': '9.74', 'groupId': 'OG000', 'lowerLimit': '4.76', 'upperLimit': '14.7'}, {'value': '11.4', 'groupId': 'OG001', 'lowerLimit': '4.95', 'upperLimit': '17.8'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Other (n=0,0,0)', 'categories': [{'measurements': [{'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG000', 'lowerLimit': 'NA', 'upperLimit': 'NA'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG001', 'lowerLimit': 'NA', 'upperLimit': 'NA'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=97,103,15)', 'categories': [{'measurements': [{'value': '11.9', 'groupId': 'OG000', 'lowerLimit': '10.0', 'upperLimit': '13.8'}, {'value': '12.4', 'groupId': 'OG001', 'lowerLimit': '9.91', 'upperLimit': '14.8'}, {'value': '9.62', 'groupId': 'OG002', 'lowerLimit': '6.79', 'upperLimit': '12.5'}]}]}], 'analyses': [{'pValue': '0.4207', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0566', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1211', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3772', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4023', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.', 'unitOfMeasure': 'kPa', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean HCV RNA Level by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1529', 'groupId': 'OG000'}, {'value': '1108', 'groupId': 'OG001'}, {'value': '165', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=809,723,115)', 'categories': [{'measurements': [{'value': '5.99', 'groupId': 'OG000', 'lowerLimit': '5.92', 'upperLimit': '6.05'}, {'value': '5.82', 'groupId': 'OG001', 'lowerLimit': '5.76', 'upperLimit': '5.87'}, {'value': '5.61', 'groupId': 'OG002', 'lowerLimit': '5.47', 'upperLimit': '5.75'}]}]}, {'title': 'G2 (n=191,111,12)', 'categories': [{'measurements': [{'value': '5.90', 'groupId': 'OG000', 'lowerLimit': '5.76', 'upperLimit': '6.03'}, {'value': '5.74', 'groupId': 'OG001', 'lowerLimit': '5.57', 'upperLimit': '5.92'}, {'value': '6.20', 'groupId': 'OG002', 'lowerLimit': '5.80', 'upperLimit': '6.59'}]}]}, {'title': 'G3 (n=350,181,26)', 'categories': [{'measurements': [{'value': '5.99', 'groupId': 'OG000', 'lowerLimit': '5.88', 'upperLimit': '6.09'}, {'value': '5.69', 'groupId': 'OG001', 'lowerLimit': '5.57', 'upperLimit': '5.80'}, {'value': '5.39', 'groupId': 'OG002', 'lowerLimit': '5.10', 'upperLimit': '5.68'}]}]}, {'title': 'G4 (n=155,82,8)', 'categories': [{'measurements': [{'value': '5.64', 'groupId': 'OG000', 'lowerLimit': '5.51', 'upperLimit': '5.77'}, {'value': '5.53', 'groupId': 'OG001', 'lowerLimit': '5.35', 'upperLimit': '5.71'}, {'value': '5.53', 'groupId': 'OG002', 'lowerLimit': '4.98', 'upperLimit': '6.07'}]}]}, {'title': 'Other (n=24,11,4)', 'categories': [{'measurements': [{'value': '5.53', 'groupId': 'OG000', 'lowerLimit': '4.95', 'upperLimit': '6.10'}, {'value': '5.13', 'groupId': 'OG001', 'lowerLimit': '4.24', 'upperLimit': '6.01'}, {'value': '6.27', 'groupId': 'OG002', 'lowerLimit': '5.13', 'upperLimit': '7.42'}]}]}, {'title': 'Total (n=1529,1108,165)', 'categories': [{'measurements': [{'value': '5.93', 'groupId': 'OG000', 'lowerLimit': '5.89', 'upperLimit': '5.98'}, {'value': '5.76', 'groupId': 'OG001', 'lowerLimit': '5.71', 'upperLimit': '5.81'}, {'value': '5.63', 'groupId': 'OG002', 'lowerLimit': '5.51', 'upperLimit': '5.75'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2132', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3031', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9550', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.', 'unitOfMeasure': 'log10 IU/mL', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean HCV RNA Level by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '679', 'groupId': 'OG000'}, {'value': '594', 'groupId': 'OG001'}, {'value': '93', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=469,480,82)', 'categories': [{'measurements': [{'value': '6.04', 'groupId': 'OG000', 'lowerLimit': '5.97', 'upperLimit': '6.12'}, {'value': '5.92', 'groupId': 'OG001', 'lowerLimit': '5.86', 'upperLimit': '5.97'}, {'value': '5.85', 'groupId': 'OG002', 'lowerLimit': '5.71', 'upperLimit': '5.99'}]}]}, {'title': 'G2 (n=81,21,6)', 'categories': [{'measurements': [{'value': '5.52', 'groupId': 'OG000', 'lowerLimit': '5.29', 'upperLimit': '5.75'}, {'value': '5.97', 'groupId': 'OG001', 'lowerLimit': '5.60', 'upperLimit': '6.33'}, {'value': '5.49', 'groupId': 'OG002', 'lowerLimit': '4.39', 'upperLimit': '6.58'}]}]}, {'title': 'G3 (n=59,39,5)', 'categories': [{'measurements': [{'value': '5.87', 'groupId': 'OG000', 'lowerLimit': '5.61', 'upperLimit': '6.13'}, {'value': '5.78', 'groupId': 'OG001', 'lowerLimit': '5.47', 'upperLimit': '6.10'}, {'value': '5.73', 'groupId': 'OG002', 'lowerLimit': '5.14', 'upperLimit': '6.32'}]}]}, {'title': 'G4 (n=59,39,0)', 'categories': [{'measurements': [{'value': '5.67', 'groupId': 'OG000', 'lowerLimit': '5.49', 'upperLimit': '5.85'}, {'value': '5.43', 'groupId': 'OG001', 'lowerLimit': '5.18', 'upperLimit': '5.69'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Other (n=11,15,0)', 'categories': [{'measurements': [{'value': '5.59', 'groupId': 'OG000', 'lowerLimit': '4.68', 'upperLimit': '6.49'}, {'value': '5.54', 'groupId': 'OG001', 'lowerLimit': '5.09', 'upperLimit': '5.99'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=679,594,93)', 'categories': [{'measurements': [{'value': '5.93', 'groupId': 'OG000', 'lowerLimit': '5.86', 'upperLimit': '5.99'}, {'value': '5.87', 'groupId': 'OG001', 'lowerLimit': '5.81', 'upperLimit': '5.92'}, {'value': '5.82', 'groupId': 'OG002', 'lowerLimit': '5.68', 'upperLimit': '5.96'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1890', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5793', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0847', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5506', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0020', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.', 'unitOfMeasure': 'log10 IU/mL', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Alanine Aminotransferase (ALT) Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '955', 'groupId': 'OG000'}, {'value': '1480', 'groupId': 'OG001'}, {'value': '416', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=488,914,269)', 'categories': [{'measurements': [{'value': '2.09', 'groupId': 'OG000', 'lowerLimit': '1.92', 'upperLimit': '2.27'}, {'value': '1.77', 'groupId': 'OG001', 'lowerLimit': '1.68', 'upperLimit': '1.86'}, {'value': '1.63', 'groupId': 'OG002', 'lowerLimit': '1.47', 'upperLimit': '1.79'}]}]}, {'title': 'G2 (n=123,152,37)', 'categories': [{'measurements': [{'value': '2.42', 'groupId': 'OG000', 'lowerLimit': '1.96', 'upperLimit': '2.88'}, {'value': '1.96', 'groupId': 'OG001', 'lowerLimit': '1.64', 'upperLimit': '2.27'}, {'value': '1.21', 'groupId': 'OG002', 'lowerLimit': '0.932', 'upperLimit': '1.48'}]}]}, {'title': 'G3 (n=228,272,65)', 'categories': [{'measurements': [{'value': '2.80', 'groupId': 'OG000', 'lowerLimit': '2.52', 'upperLimit': '3.08'}, {'value': '2.32', 'groupId': 'OG001', 'lowerLimit': '2.09', 'upperLimit': '2.55'}, {'value': '2.05', 'groupId': 'OG002', 'lowerLimit': '1.64', 'upperLimit': '2.45'}]}]}, {'title': 'G4 (n=88,121,38)', 'categories': [{'measurements': [{'value': '2.00', 'groupId': 'OG000', 'lowerLimit': '1.63', 'upperLimit': '2.37'}, {'value': '1.66', 'groupId': 'OG001', 'lowerLimit': '1.46', 'upperLimit': '1.86'}, {'value': '1.65', 'groupId': 'OG002', 'lowerLimit': '1.29', 'upperLimit': '2.01'}]}]}, {'title': 'Other (n=28,21,7)', 'categories': [{'measurements': [{'value': '1.46', 'groupId': 'OG000', 'lowerLimit': '0.964', 'upperLimit': '1.96'}, {'value': '1.72', 'groupId': 'OG001', 'lowerLimit': '1.13', 'upperLimit': '2.31'}, {'value': '1.33', 'groupId': 'OG002', 'lowerLimit': '0.686', 'upperLimit': '1.98'}]}]}, {'title': 'Total (n=955,1480,416)', 'categories': [{'measurements': [{'value': '2.28', 'groupId': 'OG000', 'lowerLimit': '2.14', 'upperLimit': '2.41'}, {'value': '1.88', 'groupId': 'OG001', 'lowerLimit': '1.80', 'upperLimit': '1.96'}, {'value': '1.65', 'groupId': 'OG002', 'lowerLimit': '1.53', 'upperLimit': '1.78'}]}]}], 'analyses': [{'pValue': '0.0007', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0061', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3885', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3597', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 international units per liter \\[IU/L\\] for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean ALT Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '398', 'groupId': 'OG000'}, {'value': '686', 'groupId': 'OG001'}, {'value': '229', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=241,528,184)', 'categories': [{'measurements': [{'value': '3.00', 'groupId': 'OG000', 'lowerLimit': '2.69', 'upperLimit': '3.32'}, {'value': '2.14', 'groupId': 'OG001', 'lowerLimit': '2.00', 'upperLimit': '2.29'}, {'value': '2.00', 'groupId': 'OG002', 'lowerLimit': '1.75', 'upperLimit': '2.25'}]}]}, {'title': 'G2 (n=80,32,9)', 'categories': [{'measurements': [{'value': '3.45', 'groupId': 'OG000', 'lowerLimit': '2.73', 'upperLimit': '4.18'}, {'value': '1.84', 'groupId': 'OG001', 'lowerLimit': '1.24', 'upperLimit': '2.43'}, {'value': '2.02', 'groupId': 'OG002', 'lowerLimit': '0.934', 'upperLimit': '3.10'}]}]}, {'title': 'G3 (n=45,66,17)', 'categories': [{'measurements': [{'value': '3.06', 'groupId': 'OG000', 'lowerLimit': '2.55', 'upperLimit': '3.58'}, {'value': '2.49', 'groupId': 'OG001', 'lowerLimit': '2.03', 'upperLimit': '2.96'}, {'value': '2.27', 'groupId': 'OG002', 'lowerLimit': '1.38', 'upperLimit': '3.16'}]}]}, {'title': 'G4 (n=23,47,17)', 'categories': [{'measurements': [{'value': '1.65', 'groupId': 'OG000', 'lowerLimit': '1.20', 'upperLimit': '2.11'}, {'value': '1.79', 'groupId': 'OG001', 'lowerLimit': '1.42', 'upperLimit': '2.16'}, {'value': '1.23', 'groupId': 'OG002', 'lowerLimit': '0.768', 'upperLimit': '1.70'}]}]}, {'title': 'Other (n=9,13,2)', 'categories': [{'measurements': [{'value': '2.99', 'groupId': 'OG000', 'lowerLimit': '1.03', 'upperLimit': '4.95'}, {'value': '1.82', 'groupId': 'OG001', 'lowerLimit': '1.06', 'upperLimit': '2.57'}, {'value': '2.17', 'groupId': 'OG002', 'lowerLimit': '-12.4', 'upperLimit': '16.8'}]}]}, {'title': 'Total (n=398,686,229)', 'categories': [{'measurements': [{'value': '3.02', 'groupId': 'OG000', 'lowerLimit': '2.77', 'upperLimit': '3.27'}, {'value': '2.13', 'groupId': 'OG001', 'lowerLimit': '2.01', 'upperLimit': '2.26'}, {'value': '1.96', 'groupId': 'OG002', 'lowerLimit': '1.75', 'upperLimit': '2.18'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0005', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0110', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0980', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2264', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean ALT Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1557', 'groupId': 'OG000'}, {'value': '1126', 'groupId': 'OG001'}, {'value': '168', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=818,737,116)', 'categories': [{'measurements': [{'value': '2.02', 'groupId': 'OG000', 'lowerLimit': '1.90', 'upperLimit': '2.15'}, {'value': '1.67', 'groupId': 'OG001', 'lowerLimit': '1.58', 'upperLimit': '1.75'}, {'value': '1.67', 'groupId': 'OG002', 'lowerLimit': '1.42', 'upperLimit': '1.92'}]}]}, {'title': 'G2 (n=192,108,12)', 'categories': [{'measurements': [{'value': '2.09', 'groupId': 'OG000', 'lowerLimit': '1.77', 'upperLimit': '2.41'}, {'value': '2.06', 'groupId': 'OG001', 'lowerLimit': '1.65', 'upperLimit': '2.46'}, {'value': '1.31', 'groupId': 'OG002', 'lowerLimit': '0.622', 'upperLimit': '2.01'}]}]}, {'title': 'G3 (n=355,183,27)', 'categories': [{'measurements': [{'value': '2.72', 'groupId': 'OG000', 'lowerLimit': '2.49', 'upperLimit': '2.96'}, {'value': '2.08', 'groupId': 'OG001', 'lowerLimit': '1.88', 'upperLimit': '2.28'}, {'value': '2.03', 'groupId': 'OG002', 'lowerLimit': '1.49', 'upperLimit': '2.57'}]}]}, {'title': 'G4 (n=155,83,9)', 'categories': [{'measurements': [{'value': '1.78', 'groupId': 'OG000', 'lowerLimit': '1.55', 'upperLimit': '2.02'}, {'value': '1.84', 'groupId': 'OG001', 'lowerLimit': '1.57', 'upperLimit': '2.10'}, {'value': '1.20', 'groupId': 'OG002', 'lowerLimit': '1.04', 'upperLimit': '1.35'}]}]}, {'title': 'Other (n=37,15,4)', 'categories': [{'measurements': [{'value': '1.66', 'groupId': 'OG000', 'lowerLimit': '1.20', 'upperLimit': '2.12'}, {'value': '1.25', 'groupId': 'OG001', 'lowerLimit': '0.803', 'upperLimit': '1.69'}, {'value': '1.56', 'groupId': 'OG002', 'lowerLimit': '0.139', 'upperLimit': '2.99'}]}]}, {'title': 'Total (n=1557,1126,168)', 'categories': [{'measurements': [{'value': '2.16', 'groupId': 'OG000', 'lowerLimit': '2.06', 'upperLimit': '2.26'}, {'value': '1.78', 'groupId': 'OG001', 'lowerLimit': '1.70', 'upperLimit': '1.86'}, {'value': '1.67', 'groupId': 'OG002', 'lowerLimit': '1.47', 'upperLimit': '1.87'}]}]}], 'analyses': [{'pValue': '0.0098', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6291', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0013', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5588', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9932', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean ALT Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '667', 'groupId': 'OG000'}, {'value': '556', 'groupId': 'OG001'}, {'value': '90', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=442,437,74)', 'categories': [{'measurements': [{'value': '2.60', 'groupId': 'OG000', 'lowerLimit': '2.39', 'upperLimit': '2.82'}, {'value': '2.11', 'groupId': 'OG001', 'lowerLimit': '1.96', 'upperLimit': '2.27'}, {'value': '2.00', 'groupId': 'OG002', 'lowerLimit': '1.71', 'upperLimit': '2.29'}]}]}, {'title': 'G2 (n=92,23,6)', 'categories': [{'measurements': [{'value': '3.26', 'groupId': 'OG000', 'lowerLimit': '2.61', 'upperLimit': '3.91'}, {'value': '1.79', 'groupId': 'OG001', 'lowerLimit': '1.06', 'upperLimit': '2.53'}, {'value': '2.04', 'groupId': 'OG002', 'lowerLimit': '0.297', 'upperLimit': '3.78'}]}]}, {'title': 'G3 (n=68,51,9)', 'categories': [{'measurements': [{'value': '3.04', 'groupId': 'OG000', 'lowerLimit': '2.62', 'upperLimit': '3.47'}, {'value': '2.29', 'groupId': 'OG001', 'lowerLimit': '1.75', 'upperLimit': '2.83'}, {'value': '1.90', 'groupId': 'OG002', 'lowerLimit': '1.28', 'upperLimit': '2.52'}]}]}, {'title': 'G4 (n=54,33,0)', 'categories': [{'measurements': [{'value': '1.58', 'groupId': 'OG000', 'lowerLimit': '1.32', 'upperLimit': '1.84'}, {'value': '1.76', 'groupId': 'OG001', 'lowerLimit': '1.25', 'upperLimit': '2.27'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Other (n=11,12,1)', 'categories': [{'measurements': [{'value': '2.78', 'groupId': 'OG000', 'lowerLimit': '1.18', 'upperLimit': '4.38'}, {'value': '1.75', 'groupId': 'OG001', 'lowerLimit': '0.949', 'upperLimit': '2.54'}, {'value': '3.32', 'comment': 'Confidence interval not presented because the analysis only included 1 participant.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=667,556,90)', 'categories': [{'measurements': [{'value': '2.66', 'groupId': 'OG000', 'lowerLimit': '2.48', 'upperLimit': '2.84'}, {'value': '2.09', 'groupId': 'OG001', 'lowerLimit': '1.95', 'upperLimit': '2.23'}, {'value': '2.01', 'groupId': 'OG002', 'lowerLimit': '1.75', 'upperLimit': '2.27'}]}]}], 'analyses': [{'pValue': '0.0007', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0020', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0013', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7166', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3217', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Aspartate Aminotransferase (AST) Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '940', 'groupId': 'OG000'}, {'value': '1444', 'groupId': 'OG001'}, {'value': '405', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=480,891,264)', 'categories': [{'measurements': [{'value': '1.62', 'groupId': 'OG000', 'lowerLimit': '1.51', 'upperLimit': '1.73'}, {'value': '1.59', 'groupId': 'OG001', 'lowerLimit': '1.51', 'upperLimit': '1.66'}, {'value': '1.46', 'groupId': 'OG002', 'lowerLimit': '1.34', 'upperLimit': '1.58'}]}]}, {'title': 'G2 (n=122,151,37)', 'categories': [{'measurements': [{'value': '1.93', 'groupId': 'OG000', 'lowerLimit': '1.61', 'upperLimit': '2.26'}, {'value': '1.63', 'groupId': 'OG001', 'lowerLimit': '1.38', 'upperLimit': '1.87'}, {'value': '1.06', 'groupId': 'OG002', 'lowerLimit': '0.827', 'upperLimit': '1.29'}]}]}, {'title': 'G3 (n=227,266,64)', 'categories': [{'measurements': [{'value': '2.17', 'groupId': 'OG000', 'lowerLimit': '2.00', 'upperLimit': '2.35'}, {'value': '1.88', 'groupId': 'OG001', 'lowerLimit': '1.69', 'upperLimit': '2.07'}, {'value': '1.44', 'groupId': 'OG002', 'lowerLimit': '1.21', 'upperLimit': '1.67'}]}]}, {'title': 'G4 (n=83,118,33)', 'categories': [{'measurements': [{'value': '1.71', 'groupId': 'OG000', 'lowerLimit': '1.39', 'upperLimit': '2.03'}, {'value': '1.54', 'groupId': 'OG001', 'lowerLimit': '1.33', 'upperLimit': '1.75'}, {'value': '1.41', 'groupId': 'OG002', 'lowerLimit': '1.12', 'upperLimit': '1.70'}]}]}, {'title': 'Other (n=28,18,7)', 'categories': [{'measurements': [{'value': '1.41', 'groupId': 'OG000', 'lowerLimit': '0.899', 'upperLimit': '1.92'}, {'value': '1.63', 'groupId': 'OG001', 'lowerLimit': '0.952', 'upperLimit': '2.31'}, {'value': '1.29', 'groupId': 'OG002', 'lowerLimit': '0.605', 'upperLimit': '1.97'}]}]}, {'title': 'Total (n=940,1444,405)', 'categories': [{'measurements': [{'value': '1.80', 'groupId': 'OG000', 'lowerLimit': '1.71', 'upperLimit': '1.89'}, {'value': '1.64', 'groupId': 'OG001', 'lowerLimit': '1.57', 'upperLimit': '1.71'}, {'value': '1.41', 'groupId': 'OG002', 'lowerLimit': '1.32', 'upperLimit': '1.50'}]}]}], 'analyses': [{'pValue': '0.1894', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0054', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5360', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2185', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean AST Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '391', 'groupId': 'OG000'}, {'value': '655', 'groupId': 'OG001'}, {'value': '218', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=234,501,173)', 'categories': [{'measurements': [{'value': '2.27', 'groupId': 'OG000', 'lowerLimit': '2.02', 'upperLimit': '2.51'}, {'value': '1.78', 'groupId': 'OG001', 'lowerLimit': '1.66', 'upperLimit': '1.90'}, {'value': '1.65', 'groupId': 'OG002', 'lowerLimit': '1.48', 'upperLimit': '1.83'}]}]}, {'title': 'G2 (n=80,32,9)', 'categories': [{'measurements': [{'value': '2.49', 'groupId': 'OG000', 'lowerLimit': '2.08', 'upperLimit': '2.90'}, {'value': '1.33', 'groupId': 'OG001', 'lowerLimit': '0.966', 'upperLimit': '1.70'}, {'value': '1.58', 'groupId': 'OG002', 'lowerLimit': '0.802', 'upperLimit': '2.36'}]}]}, {'title': 'G3 (n=45,63,17)', 'categories': [{'measurements': [{'value': '2.42', 'groupId': 'OG000', 'lowerLimit': '1.98', 'upperLimit': '2.87'}, {'value': '2.07', 'groupId': 'OG001', 'lowerLimit': '1.65', 'upperLimit': '2.50'}, {'value': '1.71', 'groupId': 'OG002', 'lowerLimit': '1.09', 'upperLimit': '2.32'}]}]}, {'title': 'G4 (n=23,46,17)', 'categories': [{'measurements': [{'value': '1.31', 'groupId': 'OG000', 'lowerLimit': '0.985', 'upperLimit': '1.63'}, {'value': '1.52', 'groupId': 'OG001', 'lowerLimit': '1.23', 'upperLimit': '1.81'}, {'value': '1.36', 'groupId': 'OG002', 'lowerLimit': '0.856', 'upperLimit': '1.86'}]}]}, {'title': 'Other (n=9,13,2)', 'categories': [{'measurements': [{'value': '1.86', 'groupId': 'OG000', 'lowerLimit': '1.00', 'upperLimit': '2.71'}, {'value': '1.47', 'groupId': 'OG001', 'lowerLimit': '1.03', 'upperLimit': '1.92'}, {'value': '1.09', 'groupId': 'OG002', 'lowerLimit': '-3.50', 'upperLimit': '5.68'}]}]}, {'title': 'Total (n=391,655,218)', 'categories': [{'measurements': [{'value': '2.27', 'groupId': 'OG000', 'lowerLimit': '2.09', 'upperLimit': '2.44'}, {'value': '1.76', 'groupId': 'OG001', 'lowerLimit': '1.66', 'upperLimit': '1.86'}, {'value': '1.63', 'groupId': 'OG002', 'lowerLimit': '1.48', 'upperLimit': '1.78'}]}]}], 'analyses': [{'pValue': '0.0002', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0003', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0106', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7821', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2372', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean AST Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1524', 'groupId': 'OG000'}, {'value': '1105', 'groupId': 'OG001'}, {'value': '160', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=800,724,111)', 'categories': [{'measurements': [{'value': '1.65', 'groupId': 'OG000', 'lowerLimit': '1.56', 'upperLimit': '1.73'}, {'value': '1.51', 'groupId': 'OG001', 'lowerLimit': '1.43', 'upperLimit': '1.59'}, {'value': '1.49', 'groupId': 'OG002', 'lowerLimit': '1.30', 'upperLimit': '1.69'}]}]}, {'title': 'G2 (n=190,108,12)', 'categories': [{'measurements': [{'value': '1.71', 'groupId': 'OG000', 'lowerLimit': '1.48', 'upperLimit': '1.94'}, {'value': '1.66', 'groupId': 'OG001', 'lowerLimit': '1.35', 'upperLimit': '1.98'}, {'value': '1.37', 'groupId': 'OG002', 'lowerLimit': '0.725', 'upperLimit': '2.02'}]}]}, {'title': 'G3 (n=350,181,26)', 'categories': [{'measurements': [{'value': '2.13', 'groupId': 'OG000', 'lowerLimit': '1.96', 'upperLimit': '2.29'}, {'value': '1.68', 'groupId': 'OG001', 'lowerLimit': '1.51', 'upperLimit': '1.85'}, {'value': '1.42', 'groupId': 'OG002', 'lowerLimit': '1.07', 'upperLimit': '1.77'}]}]}, {'title': 'G4 (n=148,79,7)', 'categories': [{'measurements': [{'value': '1.54', 'groupId': 'OG000', 'lowerLimit': '1.33', 'upperLimit': '1.75'}, {'value': '1.69', 'groupId': 'OG001', 'lowerLimit': '1.42', 'upperLimit': '1.96'}, {'value': '1.14', 'groupId': 'OG002', 'lowerLimit': '0.708', 'upperLimit': '1.58'}]}]}, {'title': 'Other (n=36,13,4)', 'categories': [{'measurements': [{'value': '1.41', 'groupId': 'OG000', 'lowerLimit': '0.996', 'upperLimit': '1.82'}, {'value': '1.62', 'groupId': 'OG001', 'lowerLimit': '0.707', 'upperLimit': '2.54'}, {'value': '1.51', 'groupId': 'OG002', 'lowerLimit': '0.0157', 'upperLimit': '3.00'}]}]}, {'title': 'Total (n=1524,1105,160)', 'categories': [{'measurements': [{'value': '1.75', 'groupId': 'OG000', 'lowerLimit': '1.68', 'upperLimit': '1.82'}, {'value': '1.57', 'groupId': 'OG001', 'lowerLimit': '1.50', 'upperLimit': '1.64'}, {'value': '1.46', 'groupId': 'OG002', 'lowerLimit': '1.30', 'upperLimit': '1.61'}]}]}], 'analyses': [{'pValue': '0.0688', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4367', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1951', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2927', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0013', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean AST Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '647', 'groupId': 'OG000'}, {'value': '531', 'groupId': 'OG001'}, {'value': '86', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=423,415,70)', 'categories': [{'measurements': [{'value': '2.01', 'groupId': 'OG000', 'lowerLimit': '1.86', 'upperLimit': '2.17'}, {'value': '1.78', 'groupId': 'OG001', 'lowerLimit': '1.65', 'upperLimit': '1.92'}, {'value': '1.66', 'groupId': 'OG002', 'lowerLimit': '1.40', 'upperLimit': '1.92'}]}]}, {'title': 'G2 (n=92,23,6)', 'categories': [{'measurements': [{'value': '2.34', 'groupId': 'OG000', 'lowerLimit': '1.97', 'upperLimit': '2.71'}, {'value': '1.36', 'groupId': 'OG001', 'lowerLimit': '0.874', 'upperLimit': '1.85'}, {'value': '1.61', 'groupId': 'OG002', 'lowerLimit': '0.494', 'upperLimit': '2.73'}]}]}, {'title': 'G3 (n=67,49,9)', 'categories': [{'measurements': [{'value': '2.36', 'groupId': 'OG000', 'lowerLimit': '2.02', 'upperLimit': '2.69'}, {'value': '1.96', 'groupId': 'OG001', 'lowerLimit': '1.44', 'upperLimit': '2.49'}, {'value': '1.63', 'groupId': 'OG002', 'lowerLimit': '0.697', 'upperLimit': '2.56'}]}]}, {'title': 'G4 (n=54,32,0)', 'categories': [{'measurements': [{'value': '1.30', 'groupId': 'OG000', 'lowerLimit': '1.13', 'upperLimit': '1.48'}, {'value': '1.65', 'groupId': 'OG001', 'lowerLimit': '1.21', 'upperLimit': '2.10'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Other (n=11,12,1)', 'categories': [{'measurements': [{'value': '1.79', 'groupId': 'OG000', 'lowerLimit': '1.11', 'upperLimit': '2.47'}, {'value': '1.41', 'groupId': 'OG001', 'lowerLimit': '0.905', 'upperLimit': '1.91'}, {'value': '1.45', 'comment': 'Confidence interval not presented because the analysis only included 1 participant.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=647,531,86)', 'categories': [{'measurements': [{'value': '2.03', 'groupId': 'OG000', 'lowerLimit': '1.91', 'upperLimit': '2.16'}, {'value': '1.77', 'groupId': 'OG001', 'lowerLimit': '1.65', 'upperLimit': '1.88'}, {'value': '1.65', 'groupId': 'OG002', 'lowerLimit': '1.42', 'upperLimit': '1.88'}]}]}], 'analyses': [{'pValue': '0.0247', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0034', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0017', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3346', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3215', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0003', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm.", 'unitOfMeasure': 'ratio', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Platelet Count by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '939', 'groupId': 'OG000'}, {'value': '1458', 'groupId': 'OG001'}, {'value': '415', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=483,900,269)', 'categories': [{'measurements': [{'value': '200', 'groupId': 'OG000', 'lowerLimit': '195', 'upperLimit': '205'}, {'value': '204', 'groupId': 'OG001', 'lowerLimit': '200', 'upperLimit': '208'}, {'value': '201', 'groupId': 'OG002', 'lowerLimit': '194', 'upperLimit': '208'}]}]}, {'title': 'G2 (n=121,147,37)', 'categories': [{'measurements': [{'value': '190', 'groupId': 'OG000', 'lowerLimit': '180', 'upperLimit': '200'}, {'value': '212', 'groupId': 'OG001', 'lowerLimit': '201', 'upperLimit': '222'}, {'value': '203', 'groupId': 'OG002', 'lowerLimit': '189', 'upperLimit': '218'}]}]}, {'title': 'G3 (n=225,268,64)', 'categories': [{'measurements': [{'value': '186', 'groupId': 'OG000', 'lowerLimit': '180', 'upperLimit': '193'}, {'value': '201', 'groupId': 'OG001', 'lowerLimit': '194', 'upperLimit': '207'}, {'value': '193', 'groupId': 'OG002', 'lowerLimit': '182', 'upperLimit': '204'}]}]}, {'title': 'G4 (n=85,124,38)', 'categories': [{'measurements': [{'value': '198', 'groupId': 'OG000', 'lowerLimit': '185', 'upperLimit': '211'}, {'value': '191', 'groupId': 'OG001', 'lowerLimit': '182', 'upperLimit': '200'}, {'value': '189', 'groupId': 'OG002', 'lowerLimit': '177', 'upperLimit': '201'}]}]}, {'title': 'Other (n=25,19,7)', 'categories': [{'measurements': [{'value': '216', 'groupId': 'OG000', 'lowerLimit': '169', 'upperLimit': '263'}, {'value': '203', 'groupId': 'OG001', 'lowerLimit': '172', 'upperLimit': '234'}, {'value': '195', 'groupId': 'OG002', 'lowerLimit': '165', 'upperLimit': '225'}]}]}, {'title': 'Total (n=939,1458,415)', 'categories': [{'measurements': [{'value': '196', 'groupId': 'OG000', 'lowerLimit': '192', 'upperLimit': '199'}, {'value': '203', 'groupId': 'OG001', 'lowerLimit': '200', 'upperLimit': '206'}, {'value': '199', 'groupId': 'OG002', 'lowerLimit': '194', 'upperLimit': '204'}]}]}], 'analyses': [{'pValue': '0.3609', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0018', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0356', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7044', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8578', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0076', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells per liter (10\\^9 cells/L).', 'unitOfMeasure': '10^9 cells/L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Platelet Count by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '383', 'groupId': 'OG000'}, {'value': '651', 'groupId': 'OG001'}, {'value': '210', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=233,501,167)', 'categories': [{'measurements': [{'value': '180', 'groupId': 'OG000', 'lowerLimit': '173', 'upperLimit': '186'}, {'value': '196', 'groupId': 'OG001', 'lowerLimit': '191', 'upperLimit': '202'}, {'value': '197', 'groupId': 'OG002', 'lowerLimit': '189', 'upperLimit': '205'}]}]}, {'title': 'G2 (n=74,29,8)', 'categories': [{'measurements': [{'value': '166', 'groupId': 'OG000', 'lowerLimit': '154', 'upperLimit': '178'}, {'value': '181', 'groupId': 'OG001', 'lowerLimit': '167', 'upperLimit': '195'}, {'value': '165', 'groupId': 'OG002', 'lowerLimit': '102', 'upperLimit': '228'}]}]}, {'title': 'G3 (n=46,65,17)', 'categories': [{'measurements': [{'value': '182', 'groupId': 'OG000', 'lowerLimit': '167', 'upperLimit': '197'}, {'value': '191', 'groupId': 'OG001', 'lowerLimit': '176', 'upperLimit': '206'}, {'value': '191', 'groupId': 'OG002', 'lowerLimit': '161', 'upperLimit': '221'}]}]}, {'title': 'G4 (n=22,43,17)', 'categories': [{'measurements': [{'value': '194', 'groupId': 'OG000', 'lowerLimit': '180', 'upperLimit': '208'}, {'value': '184', 'groupId': 'OG001', 'lowerLimit': '171', 'upperLimit': '197'}, {'value': '185', 'groupId': 'OG002', 'lowerLimit': '161', 'upperLimit': '209'}]}]}, {'title': 'Other (n=8,13,1)', 'categories': [{'measurements': [{'value': '173.', 'groupId': 'OG000', 'lowerLimit': '142', 'upperLimit': '204'}, {'value': '202', 'groupId': 'OG001', 'lowerLimit': '150', 'upperLimit': '255'}, {'value': '209', 'comment': 'Confidence interval not presented because the analysis only included 1 participant.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=383,651,210)', 'categories': [{'measurements': [{'value': '178', 'groupId': 'OG000', 'lowerLimit': '173', 'upperLimit': '183'}, {'value': '194', 'groupId': 'OG001', 'lowerLimit': '190', 'upperLimit': '199'}, {'value': '194', 'groupId': 'OG002', 'lowerLimit': '187', 'upperLimit': '202'}]}]}], 'analyses': [{'pValue': '0.0002', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2017', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5878', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4144', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4492', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.', 'unitOfMeasure': '10^9 cells/L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Platelet Count by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1538', 'groupId': 'OG000'}, {'value': '1106', 'groupId': 'OG001'}, {'value': '168', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=810,727,115)', 'categories': [{'measurements': [{'value': '200', 'groupId': 'OG000', 'lowerLimit': '196', 'upperLimit': '203'}, {'value': '205', 'groupId': 'OG001', 'lowerLimit': '200', 'upperLimit': '210'}, {'value': '203', 'groupId': 'OG002', 'lowerLimit': '191', 'upperLimit': '215'}]}]}, {'title': 'G2 (n=188,105,12)', 'categories': [{'measurements': [{'value': '199', 'groupId': 'OG000', 'lowerLimit': '190', 'upperLimit': '207'}, {'value': '209', 'groupId': 'OG001', 'lowerLimit': '198', 'upperLimit': '219'}, {'value': '194', 'groupId': 'OG002', 'lowerLimit': '158', 'upperLimit': '229'}]}]}, {'title': 'G3 (n=351,179,27)', 'categories': [{'measurements': [{'value': '191', 'groupId': 'OG000', 'lowerLimit': '185', 'upperLimit': '196'}, {'value': '201', 'groupId': 'OG001', 'lowerLimit': '193', 'upperLimit': '208'}, {'value': '196', 'groupId': 'OG002', 'lowerLimit': '178', 'upperLimit': '214'}]}]}, {'title': 'G4 (n=156,81,10)', 'categories': [{'measurements': [{'value': '195', 'groupId': 'OG000', 'lowerLimit': '187', 'upperLimit': '204'}, {'value': '190', 'groupId': 'OG001', 'lowerLimit': '178', 'upperLimit': '202'}, {'value': '185', 'groupId': 'OG002', 'lowerLimit': '159', 'upperLimit': '211'}]}]}, {'title': 'Other (n=33,14,4)', 'categories': [{'measurements': [{'value': '216', 'groupId': 'OG000', 'lowerLimit': '180', 'upperLimit': '252'}, {'value': '193', 'groupId': 'OG001', 'lowerLimit': '157', 'upperLimit': '229'}, {'value': '199', 'groupId': 'OG002', 'lowerLimit': '139', 'upperLimit': '258'}]}]}, {'title': 'Total (n=1538,1106,168)', 'categories': [{'measurements': [{'value': '197', 'groupId': 'OG000', 'lowerLimit': '194', 'upperLimit': '200'}, {'value': '203', 'groupId': 'OG001', 'lowerLimit': '200', 'upperLimit': '207'}, {'value': '200', 'groupId': 'OG002', 'lowerLimit': '191', 'upperLimit': '209'}]}]}], 'analyses': [{'pValue': '0.0671', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1009', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0635', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4162', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9305', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0041', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.', 'unitOfMeasure': '10^9 cells/L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Mean Platelet Count by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '641', 'groupId': 'OG000'}, {'value': '519', 'groupId': 'OG001'}, {'value': '84', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1 (n=426,406,69)', 'categories': [{'measurements': [{'value': '186', 'groupId': 'OG000', 'lowerLimit': '181', 'upperLimit': '192'}, {'value': '199', 'groupId': 'OG001', 'lowerLimit': '192', 'upperLimit': '205'}, {'value': '190', 'groupId': 'OG002', 'lowerLimit': '180', 'upperLimit': '200'}]}]}, {'title': 'G2 (n=84,21,6)', 'categories': [{'measurements': [{'value': '167', 'groupId': 'OG000', 'lowerLimit': '156', 'upperLimit': '178'}, {'value': '184', 'groupId': 'OG001', 'lowerLimit': '157', 'upperLimit': '210'}, {'value': '162', 'groupId': 'OG002', 'lowerLimit': '126', 'upperLimit': '197'}]}]}, {'title': 'G3 (n=68,51,9)', 'categories': [{'measurements': [{'value': '180', 'groupId': 'OG000', 'lowerLimit': '168', 'upperLimit': '191'}, {'value': '199', 'groupId': 'OG001', 'lowerLimit': '180', 'upperLimit': '219'}, {'value': '182', 'groupId': 'OG002', 'lowerLimit': '149', 'upperLimit': '214'}]}]}, {'title': 'G4 (n=53,29,0)', 'categories': [{'measurements': [{'value': '189', 'groupId': 'OG000', 'lowerLimit': '178', 'upperLimit': '200'}, {'value': '182', 'groupId': 'OG001', 'lowerLimit': '167', 'upperLimit': '197'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Other (n=10,12,0)', 'categories': [{'measurements': [{'value': '194', 'groupId': 'OG000', 'lowerLimit': '131', 'upperLimit': '257'}, {'value': '190', 'groupId': 'OG001', 'lowerLimit': '155', 'upperLimit': '226'}, {'value': 'NA', 'comment': 'The total number of participants analyzed in this arm/group by category was 0.', 'groupId': 'OG002', 'lowerLimit': 'NA', 'upperLimit': 'NA'}]}]}, {'title': 'Total (n=641,519,64)', 'categories': [{'measurements': [{'value': '183', 'groupId': 'OG000', 'lowerLimit': '179', 'upperLimit': '188'}, {'value': '197', 'groupId': 'OG001', 'lowerLimit': '192', 'upperLimit': '202'}, {'value': '187', 'groupId': 'OG002', 'lowerLimit': '178', 'upperLimit': '196'}]}]}], 'analyses': [{'pValue': '0.0059', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2808', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2401', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2993', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5529', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0005', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of a continuous variable across the three IL28B genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'MEAN', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.', 'unitOfMeasure': '10^9 cells/L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Region: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '978', 'groupId': 'OG000'}, {'value': '1518', 'groupId': 'OG001'}, {'value': '420', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Asia (n=500,930,272)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Europe (n=500,930,272)', 'categories': [{'measurements': [{'value': '388', 'groupId': 'OG000'}, {'value': '680', 'groupId': 'OG001'}, {'value': '183', 'groupId': 'OG002'}]}]}, {'title': 'G1, Middle East (n=500,930,272)', 'categories': [{'measurements': [{'value': '65', 'groupId': 'OG000'}, {'value': '167', 'groupId': 'OG001'}, {'value': '57', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latin America (n=500,930,272)', 'categories': [{'measurements': [{'value': '31', 'groupId': 'OG000'}, {'value': '74', 'groupId': 'OG001'}, {'value': '32', 'groupId': 'OG002'}]}]}, {'title': 'G2, Asia (n=126,160,37)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Europe (n=126,160,37)', 'categories': [{'measurements': [{'value': '111', 'groupId': 'OG000'}, {'value': '144', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'G2, Middle East (n=126,160,37)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latin America (n=126,160,37)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Asia (n=232,277,65)', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '52', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Europe (n=232,277,65)', 'categories': [{'measurements': [{'value': '177', 'groupId': 'OG000'}, {'value': '200', 'groupId': 'OG001'}, {'value': '55', 'groupId': 'OG002'}]}]}, {'title': 'G3, Middle East (n=232,277,65)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latin America (n=232,277,65)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Asia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Europe (n=92,129,39)', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '64', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'G4, Middle East (n=92,129,39)', 'categories': [{'measurements': [{'value': '53', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latin America (n=92,129,39)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Asia (n=28,22,7)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Europe (n=28,22,7)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Middle East (n=28,22,7)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latin America (n=28,22,7)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Asia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '78', 'groupId': 'OG000'}, {'value': '66', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Europe (n=978,1518,420)', 'categories': [{'measurements': [{'value': '721', 'groupId': 'OG000'}, {'value': '1095', 'groupId': 'OG001'}, {'value': '303', 'groupId': 'OG002'}]}]}, {'title': 'Total, Middle East (n=978,1518,420)', 'categories': [{'measurements': [{'value': '138', 'groupId': 'OG000'}, {'value': '272', 'groupId': 'OG001'}, {'value': '75', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latin America (n=978,1518,420)', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '85', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3572', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2041', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0467', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0525', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Region: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '490', 'groupId': 'OG000'}, {'value': '914', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Asia (n=295,703,239)', 'categories': [{'measurements': [{'value': '83', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Europe (n=295,703,239)', 'categories': [{'measurements': [{'value': '174', 'groupId': 'OG000'}, {'value': '534', 'groupId': 'OG001'}, {'value': '186', 'groupId': 'OG002'}]}]}, {'title': 'G1, Middle East (n=295,703,239)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '87', 'groupId': 'OG001'}, {'value': '30', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latin America (n=295,703,239)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '69', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G2, Asia (n=92,38,11)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Europe (n=92,38,11)', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '28', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G2, Middle East (n=92,38,11)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latin America (n=92,38,11)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Asia (n=63,84,20)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Europe (n=63,84,20)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '61', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G3, Middle East (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latin America (n=63,84,20)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Asia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Europe (n=26,67,21)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '36', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G4, Middle East (n=26,67,21)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latin America (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Asia (n=14,22,5)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Europe (n=14,22,5)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Middle East (n=14,22,5)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latin America (n=14,22,5)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Asia (n=490,914,296)', 'categories': [{'measurements': [{'value': '155', 'groupId': 'OG000'}, {'value': '36', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Europe (n=490,914,296)', 'categories': [{'measurements': [{'value': '275', 'groupId': 'OG000'}, {'value': '664', 'groupId': 'OG001'}, {'value': '222', 'groupId': 'OG002'}]}]}, {'title': 'Total, Middle East (n=490,914,296)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '135', 'groupId': 'OG001'}, {'value': '43', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latin America (n=490,914,296)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '79', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5275', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6593', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0372', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Region: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1598', 'groupId': 'OG000'}, {'value': '1147', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Asia (n=837,747,118)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Europe (n=837,747,118)', 'categories': [{'measurements': [{'value': '632', 'groupId': 'OG000'}, {'value': '543', 'groupId': 'OG001'}, {'value': '76', 'groupId': 'OG002'}]}]}, {'title': 'G1, Middle East (n=837,747,118)', 'categories': [{'measurements': [{'value': '138', 'groupId': 'OG000'}, {'value': '130', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latin America (n=837,747,118)', 'categories': [{'measurements': [{'value': '48', 'groupId': 'OG000'}, {'value': '68', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G2, Asia 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{'title': 'Total, Asia (n=851,730,119)', 'categories': [{'measurements': [{'value': '164', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Europe (n=851,730,119)', 'categories': [{'measurements': [{'value': '541', 'groupId': 'OG000'}, {'value': '537', 'groupId': 'OG001'}, {'value': '83', 'groupId': 'OG002'}]}]}, {'title': 'Total, Middle East (n=851,730,119)', 'categories': [{'measurements': [{'value': '97', 'groupId': 'OG000'}, {'value': '98', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latin America (n=851,730,119)', 'categories': [{'measurements': [{'value': '49', 'groupId': 'OG000'}, {'value': '68', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of 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{'title': 'G1, Estonia (n=500,930,272)', 'categories': [{'measurements': [{'value': '44', 'groupId': 'OG000'}, {'value': '70', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=500,930,272)', 'categories': [{'measurements': [{'value': '48', 'groupId': 'OG000'}, {'value': '76', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=500,930,272)', 'categories': [{'measurements': [{'value': '30', 'groupId': 'OG000'}, {'value': '54', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=500,930,272)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '35', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=500,930,272)', 'categories': [{'measurements': [{'value': '101', 'groupId': 'OG000'}, {'value': '167', 'groupId': 'OG001'}, {'value': '59', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=500,930,272)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=500,930,272)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=500,930,272)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=500,930,272)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '46', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=500,930,272)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=500,930,272)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=500,930,272)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=500,930,272)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=500,930,272)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '35', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=500,930,272)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=500,930,272)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=500,930,272)', 'categories': [{'measurements': [{'value': '60', 'groupId': 'OG000'}, {'value': '121', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=500,930,272)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=500,930,272)', 'categories': [{'measurements': [{'value': '54', 'groupId': 'OG000'}, {'value': '138', 'groupId': 'OG001'}, {'value': '51', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=500,930,272)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=500,930,272)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=500,930,272)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=500,930,272)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=500,930,272)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=500,930,272)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=500,930,272)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=126,160,37)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=126,160,37)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=126,160,37)', 'categories': [{'measurements': [{'value': '81', 'groupId': 'OG000'}, {'value': '117', 'groupId': 'OG001'}, {'value': '30', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=126,160,37)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=126,160,37)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=126,160,37)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=126,160,37)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=126,160,37)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=126,160,37)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=126,160,37)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=126,160,37)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=126,160,37)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=232,277,65)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=232,277,65)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=232,277,65)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '25', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=232,277,65)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=232,277,65)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=232,277,65)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=232,277,65)', 'categories': [{'measurements': [{'value': '70', 'groupId': 'OG000'}, {'value': '70', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=232,277,65)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=232,277,65)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=232,277,65)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=232,277,65)', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '52', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=232,277,65)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=232,277,65)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=232,277,65)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=232,277,65)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=232,277,65)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=232,277,65)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=232,277,65)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=232,277,65)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=232,277,65)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=232,277,65)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0103', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8373', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3672', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '978', 'groupId': 'OG000'}, {'value': '1518', 'groupId': 'OG001'}, {'value': '420', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=92,129,39)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '28', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=92,129,39)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=92,129,39)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=92,129,39)', 'categories': [{'measurements': [{'value': '25', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=92,129,39)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=92,129,39)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=92,129,39)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=92,129,39)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=92,129,39)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=92,129,39)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=28,22,7)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=28,22,7)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=28,22,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=28,22,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=28,22,7)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=28,22,7)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=28,22,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=28,22,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=28,22,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=978,1518,420)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=978,1518,420)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '60', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=978,1518,420)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=978,1518,420)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '28', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '74', 'groupId': 'OG000'}, {'value': '102', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=978,1518,420)', 'categories': [{'measurements': [{'value': '62', 'groupId': 'OG000'}, {'value': '108', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=978,1518,420)', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '71', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=978,1518,420)', 'categories': [{'measurements': [{'value': '52', 'groupId': 'OG000'}, {'value': '70', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=978,1518,420)', 'categories': [{'measurements': [{'value': '277', 'groupId': 'OG000'}, {'value': '389', 'groupId': 'OG001'}, {'value': '125', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=978,1518,420)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=978,1518,420)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=978,1518,420)', 'categories': [{'measurements': [{'value': '38', 'groupId': 'OG000'}, {'value': '64', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '24', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=978,1518,420)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=978,1518,420)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=978,1518,420)', 'categories': [{'measurements': [{'value': '50', 'groupId': 'OG000'}, {'value': '60', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=978,1518,420)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '36', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=978,1518,420)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=978,1518,420)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=978,1518,420)', 'categories': [{'measurements': [{'value': '61', 'groupId': 'OG000'}, {'value': '122', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=978,1518,420)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=978,1518,420)', 'categories': [{'measurements': [{'value': '74', 'groupId': 'OG000'}, {'value': '172', 'groupId': 'OG001'}, {'value': '56', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=978,1518,420)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=978,1518,420)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=978,1518,420)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=978,1518,420)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=978,1518,420)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=978,1518,420)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0637', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0474', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '490', 'groupId': 'OG000'}, {'value': '914', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=295,703,239)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=295,703,239)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '37', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=295,703,239)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=295,703,239)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=295,703,239)', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '125', 'groupId': 'OG001'}, {'value': '44', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=295,703,239)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '36', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=295,703,239)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=295,703,239)', 'categories': [{'measurements': [{'value': '40', 'groupId': 'OG000'}, {'value': '117', 'groupId': 'OG001'}, {'value': '46', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=295,703,239)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=295,703,239)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=295,703,239)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=295,703,239)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=295,703,239)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=295,703,239)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=295,703,239)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '80', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=295,703,239)', 'categories': [{'measurements': [{'value': '81', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=295,703,239)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '59', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=295,703,239)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=295,703,239)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=92,38,11)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=92,38,11)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=92,38,11)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=92,38,11)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=92,38,11)', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=92,38,11)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=92,38,11)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=92,38,11)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=63,84,20)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=63,84,20)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=63,84,20)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=63,84,20)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=63,84,20)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=63,84,20)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=63,84,20)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=63,84,20)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=63,84,20)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=63,84,20)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=63,84,20)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=63,84,20)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=63,84,20)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5522', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '490', 'groupId': 'OG000'}, {'value': '914', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=26,67,21)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=26,67,21)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '25', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=26,67,21)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=26,67,21)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=26,67,21)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=26,67,21)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=26,67,21)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=26,67,21)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=26,67,21)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=26,67,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=14,22,5)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=14,22,5)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=14,22,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=14,22,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=14,22,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=14,22,5)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=14,22,5)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=14,22,5)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=14,22,5)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=490,914,296)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=490,914,296)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '47', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=490,914,296)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=490,914,296)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=490,914,296)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=490,914,296)', 'categories': [{'measurements': [{'value': '68', 'groupId': 'OG000'}, {'value': '162', 'groupId': 'OG001'}, {'value': '54', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=490,914,296)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=490,914,296)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=490,914,296)', 'categories': [{'measurements': [{'value': '76', 'groupId': 'OG000'}, {'value': '157', 'groupId': 'OG001'}, {'value': '56', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=490,914,296)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=490,914,296)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=490,914,296)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=490,914,296)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '57', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=490,914,296)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=490,914,296)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=490,914,296)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=490,914,296)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=490,914,296)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=490,914,296)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=490,914,296)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=490,914,296)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '80', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=490,914,296)', 'categories': [{'measurements': [{'value': '144', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=490,914,296)', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '75', 'groupId': 'OG001'}, {'value': '29', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=490,914,296)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=490,914,296)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=490,914,296)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=490,914,296)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=490,914,296)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=490,914,296)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=490,914,296)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.5117', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3437', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1598', 'groupId': 'OG000'}, {'value': '1147', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=837,747,118)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=837,747,118)', 'categories': [{'measurements': [{'value': '32', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=837,747,118)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=837,747,118)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=837,747,118)', 'categories': [{'measurements': [{'value': '62', 'groupId': 'OG000'}, {'value': '58', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=837,747,118)', 'categories': [{'measurements': [{'value': '82', 'groupId': 'OG000'}, {'value': '53', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=837,747,118)', 'categories': [{'measurements': [{'value': '50', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=837,747,118)', 'categories': [{'measurements': [{'value': '35', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=837,747,118)', 'categories': [{'measurements': [{'value': '160', 'groupId': 'OG000'}, {'value': '139', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=837,747,118)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=837,747,118)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=837,747,118)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=837,747,118)', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=837,747,118)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=837,747,118)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=837,747,118)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=837,747,118)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=837,747,118)', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '31', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=837,747,118)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=837,747,118)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=837,747,118)', 'categories': [{'measurements': [{'value': '97', 'groupId': 'OG000'}, {'value': '102', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=837,747,118)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=837,747,118)', 'categories': [{'measurements': [{'value': '110', 'groupId': 'OG000'}, {'value': '115', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=837,747,118)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=837,747,118)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=837,747,118)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=837,747,118)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=837,747,118)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=837,747,118)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=837,747,118)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=198,113,12)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=198,113,12)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=198,113,12)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=198,113,12)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=198,113,12)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=198,113,12)', 'categories': [{'measurements': [{'value': '128', 'groupId': 'OG000'}, {'value': '91', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=198,113,12)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=198,113,12)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=198,113,12)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=198,113,12)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=198,113,12)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=198,113,12)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=198,113,12)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=198,113,12)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=198,113,12)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=198,113,12)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=198,113,12)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=198,113,12)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=361,186,27)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=361,186,27)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=361,186,27)', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=361,186,27)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=361,186,27)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=361,186,27)', 'categories': [{'measurements': [{'value': '34', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=361,186,27)', 'categories': [{'measurements': [{'value': '109', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=361,186,27)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=361,186,27)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=361,186,27)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=361,186,27)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=361,186,27)', 'categories': [{'measurements': [{'value': '67', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=361,186,27)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=361,186,27)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=361,186,27)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=361,186,27)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=361,186,27)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=361,186,27)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=361,186,27)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=361,186,27)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=361,186,27)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=361,186,27)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0381', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6852', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1185', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '1598', 'groupId': 'OG000'}, {'value': '1147', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs8099917 TT', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs8099917 TG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs8099917 GG', 'description': "Treatment-naive participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=165,85,10)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=165,85,10)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=165,85,10)', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=165,85,10)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=165,85,10)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=165,85,10)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=165,85,10)', 'categories': [{'measurements': [{'value': '47', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=165,85,10)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=165,85,10)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=165,85,10)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=165,85,10)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=165,85,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=165,85,10)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=165,85,10)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=165,85,10)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=165,85,10)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=37,16,4)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=37,16,4)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=37,16,4)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=37,16,4)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=37,16,4)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=37,16,4)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=37,16,4)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '61', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '105', 'groupId': 'OG000'}, {'value': '85', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '111', 'groupId': 'OG000'}, {'value': '75', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '70', 'groupId': 'OG000'}, {'value': '55', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '80', 'groupId': 'OG000'}, {'value': '56', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '445', 'groupId': 'OG000'}, {'value': '295', 'groupId': 'OG001'}, {'value': '51', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '68', 'groupId': 'OG000'}, {'value': '44', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '30', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '76', 'groupId': 'OG000'}, {'value': '37', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '31', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '99', 'groupId': 'OG000'}, {'value': '102', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '149', 'groupId': 'OG000'}, {'value': '133', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=1598,1147,171)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.2611', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6059', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '851', 'groupId': 'OG000'}, {'value': '730', 'groupId': 'OG001'}, {'value': '119', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=563,574,100)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=563,574,100)', 'categories': [{'measurements': [{'value': '28', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=563,574,100)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=563,574,100)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=563,574,100)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=563,574,100)', 'categories': [{'measurements': [{'value': '80', 'groupId': 'OG000'}, {'value': '117', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=563,574,100)', 'categories': [{'measurements': [{'value': '33', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=563,574,100)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=563,574,100)', 'categories': [{'measurements': [{'value': '88', 'groupId': 'OG000'}, {'value': '98', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=563,574,100)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=563,574,100)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=563,574,100)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=563,574,100)', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=563,574,100)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=563,574,100)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=563,574,100)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=563,574,100)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=563,574,100)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=563,574,100)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=563,574,100)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=563,574,100)', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '66', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=563,574,100)', 'categories': [{'measurements': [{'value': '84', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=563,574,100)', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '46', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=563,574,100)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=563,574,100)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=563,574,100)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=563,574,100)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=563,574,100)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=563,574,100)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=563,574,100)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=107,27,7)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=107,27,7)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=107,27,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=107,27,7)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=107,27,7)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=107,27,7)', 'categories': [{'measurements': [{'value': '61', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=107,27,7)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=107,27,7)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=107,27,7)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=93,65,9)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=93,65,9)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=93,65,9)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=93,65,9)', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=93,65,9)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=93,65,9)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=93,65,9)', 'categories': [{'measurements': [{'value': '22', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=93,65,9)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=93,65,9)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=93,65,9)', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=93,65,9)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=93,65,9)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=93,65,9)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=93,65,9)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=93,65,9)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0048', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5127', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '851', 'groupId': 'OG000'}, {'value': '730', 'groupId': 'OG001'}, {'value': '119', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=71,43,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=71,43,0)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=71,43,0)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=71,43,0)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=71,43,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=71,43,0)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=71,43,0)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=71,43,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=71,43,0)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=71,43,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=71,43,0)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=71,43,0)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=17,21,3)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=17,21,3)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=17,21,3)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=17,21,3)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=17,21,3)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=17,21,3)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=17,21,3)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=17,21,3)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=17,21,3)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=851,730,119)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=851,730,119)', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=851,730,119)', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=851,730,119)', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=851,730,119)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=851,730,119)', 'categories': [{'measurements': [{'value': '129', 'groupId': 'OG000'}, {'value': '141', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=851,730,119)', 'categories': [{'measurements': [{'value': '39', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=851,730,119)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=851,730,119)', 'categories': [{'measurements': [{'value': '140', 'groupId': 'OG000'}, {'value': '128', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=851,730,119)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=851,730,119)', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '34', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=851,730,119)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=851,730,119)', 'categories': [{'measurements': [{'value': '40', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=851,730,119)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=851,730,119)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=851,730,119)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=851,730,119)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=851,730,119)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=851,730,119)', 'categories': [{'measurements': [{'value': '42', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=851,730,119)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=851,730,119)', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '66', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=851,730,119)', 'categories': [{'measurements': [{'value': '149', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=851,730,119)', 'categories': [{'measurements': [{'value': '47', 'groupId': 'OG000'}, {'value': '60', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=851,730,119)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=851,730,119)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=851,730,119)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=851,730,119)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=851,730,119)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=851,730,119)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=851,730,119)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.3465', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7358', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the IL28B distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by IL28B Genotype rs8099917 Category: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '978', 'groupId': 'OG000'}, {'value': '1518', 'groupId': 'OG001'}, {'value': '420', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: IL28B rs12979860 CC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: IL28B rs12979860 TC', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: IL28B rs12979860 TT', 'description': "Treatment-naive participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'Naive: IL28B rs8099917 TT', 'categories': [{'measurements': [{'value': '974', 'groupId': 'OG000'}, {'value': '550', 'groupId': 'OG001'}, {'value': '74', 'groupId': 'OG002'}]}]}, {'title': 'Naive: IL28B rs8099917 TG', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '965', 'groupId': 'OG001'}, {'value': '178', 'groupId': 'OG002'}]}]}, {'title': 'Naive: IL28B rs8099917 GG', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '168', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by IL28B Genotype rs8099917 Category: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '490', 'groupId': 'OG000'}, {'value': '914', 'groupId': 'OG001'}, {'value': '296', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'Experienced: IL28B rs8099917 TT', 'categories': [{'measurements': [{'value': '489', 'groupId': 'OG000'}, {'value': '314', 'groupId': 'OG001'}, {'value': '48', 'groupId': 'OG002'}]}]}, {'title': 'Experienced: IL28B rs8099917 TG', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '597', 'groupId': 'OG001'}, {'value': '132', 'groupId': 'OG002'}]}]}, {'title': 'Experienced: IL28B rs8099917 GG', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '116', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Inosine Triphosphatase (ITPA) Genotype rs7270101 by ITPA Genotype rs1127354 Category: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '36', 'groupId': 'OG000'}, {'value': '491', 'groupId': 'OG001'}, {'value': '2389', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs7270101 CC', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs7270101 Alanine-Cysteine (AC)', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs7270101 Alanine-Alanine (AA)', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'Naive: ITPA rs1127354 AA', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Naive: ITPA rs1127354 Cysteine-Alanine (CA)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '34', 'groupId': 'OG001'}, {'value': '343', 'groupId': 'OG002'}]}]}, {'title': 'Naive: ITPA rs1127354 CC', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '457', 'groupId': 'OG001'}, {'value': '2035', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by ITPA Genotype rs1127354 Category: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '18', 'groupId': 'OG000'}, {'value': '269', 'groupId': 'OG001'}, {'value': '1411', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs7270101 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs7270101 AC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs7270101 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'Experienced: ITPA rs1127354 AA', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Experienced: ITPA rs1127354 CA', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '211', 'groupId': 'OG002'}]}]}, {'title': 'Experienced: ITPA rs1127354 CC', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '246', 'groupId': 'OG001'}, {'value': '1185', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0066', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Tests for association between the two variables', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Region: Treatment-Naive', 'denoms': [{'units': 'Participants', 'counts': [{'value': '11', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '2528', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs1127354 AA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs1127354 CA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs1127354 CC', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Asia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Europe (n=9,212,1481)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '167', 'groupId': 'OG001'}, {'value': '1077', 'groupId': 'OG002'}]}]}, {'title': 'G1, Middle East (n=9,212,1481)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '255', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latin America (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '132', 'groupId': 'OG002'}]}]}, {'title': 'G2, Asia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Europe (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '37', 'groupId': 'OG001'}, {'value': '254', 'groupId': 'OG002'}]}]}, {'title': 'G2, Middle East (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latin America (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Asia (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '88', 'groupId': 'OG002'}]}]}, {'title': 'G3, Europe (n=1,83,490)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '369', 'groupId': 'OG002'}]}]}, {'title': 'G3, Middle East (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latin America (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Asia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Europe (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '112', 'groupId': 'OG002'}]}]}, {'title': 'G4, Middle East (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '113', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latin America (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Other, Asia (n=1,7,49)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'Other, Europe (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Other, Middle East (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latin America (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Asia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}, {'value': '121', 'groupId': 'OG002'}]}]}, {'title': 'Total, Europe (n=11,377,2528)', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '284', 'groupId': 'OG001'}, {'value': '1827', 'groupId': 'OG002'}]}]}, {'title': 'Total, Middle East (n=11,377,2528)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '55', 'groupId': 'OG001'}, {'value': '428', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latin America (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '152', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0018', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0425', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9829', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.6700', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7672', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0067', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Region: Treatment-Experienced', 'denoms': [{'units': 'Participants', 'counts': [{'value': '15', 'groupId': 'OG000'}, {'value': '235', 'groupId': 'OG001'}, {'value': '1449', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs1127354 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs1127354 CA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 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'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '11', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '2528', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs1127354 AA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs1127354 CA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs1127354 CC', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '57', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '114', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=9,212,1481)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '121', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=9,212,1481)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '86', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=9,212,1481)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '62', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=9,212,1481)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '280', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=9,212,1481)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '59', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '58', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '183', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=9,212,1481)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '28', 'groupId': 'OG001'}, {'value': '214', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=9,212,1481)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=9,212,1481)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '199', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=0,45,278)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '52', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '136', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '88', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=1,83,490)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=1,83,490)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1947', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0226', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '11', 'groupId': 'OG000'}, {'value': '377', 'groupId': 'OG001'}, {'value': '2528', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs1127354 AA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs1127354 CA', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs1127354 CC', 'description': "Treatment-naive participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '54', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '63', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=0,30,230)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=1,7,49)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=1,7,49)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '93', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '54', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '176', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}, {'value': '171', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=11,377,2528)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '112', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '128', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=11,377,2528)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '109', 'groupId': 'OG001'}, {'value': '680', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '54', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '97', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '37', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '97', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '60', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '185', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '38', 'groupId': 'OG001'}, {'value': '263', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '33', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=11,377,2528)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=11,377,2528)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.1158', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3675', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0948', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '15', 'groupId': 'OG000'}, {'value': '235', 'groupId': 'OG001'}, {'value': '1449', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs1127354 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs1127354 CA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs1127354 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '52', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=10,169,1057)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=10,169,1057)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '185', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=10,169,1057)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '60', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=10,169,1057)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '177', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=10,169,1057)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '29', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '114', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=10,169,1057)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '64', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '82', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=10,169,1057)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '32', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=3,30,108)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=3,30,108)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '45', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=3,30,10)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=3,30,108)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=2,26,139)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '29', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=2,26,139)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=2,26,139)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.1236', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0119', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7472', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '15', 'groupId': 'OG000'}, {'value': '235', 'groupId': 'OG001'}, {'value': '1449', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs1127354 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs1127354 CA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs1127354 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '38', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=0,5,109)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=0,5,36)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=15,235,1449)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '72', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '30', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '39', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=15,235,1449)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=15,235,1449)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '255', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=15,235,1449)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '69', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '35', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=15,235,1449)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '34', 'groupId': 'OG001'}, {'value': '252', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '52', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=15,235,1449)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '62', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=15,235,1449)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '56', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '114', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=15,235,1449)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '48', 'groupId': 'OG001'}, {'value': '112', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '106', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=15,235,1449)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.9734', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8303', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0006', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '36', 'groupId': 'OG000'}, {'value': '491', 'groupId': 'OG001'}, {'value': '2389', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs7270101 CC', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs7270101 AC', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs7270101 AA', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '59', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=17,300,1385)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '104', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=17,300,1385)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '110', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '87', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '61', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=17,300,1385)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '57', 'groupId': 'OG001'}, {'value': '264', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=17,300,1385)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '55', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '58', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=17,300,1385)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '167', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '202', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=17,300,1385)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=17,300,1385)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=17,300,1385)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=6,56,261)', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}, {'value': '182', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=6,56,261)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=9,81,484)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '46', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=9,81,484)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=9,81,484)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=9,81,484)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '137', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=9,81,484)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '98', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=9,81,484)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0065', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9999', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3472', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '36', 'groupId': 'OG000'}, {'value': '491', 'groupId': 'OG001'}, {'value': '2389', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Naive: ITPA rs7270101 CC', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Naive: ITPA rs7270101 AC', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Naive: ITPA rs7270101 AA', 'description': "Treatment-naive participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=3,51,206)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '51', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=3,51,206)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '10', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=3,51,206)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=1,3,53)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=1,3,53)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=36,491,2389)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '93', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=36,491,2389)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=36,491,2389)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '33', 'groupId': 'OG001'}, {'value': '160', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=36,491,2389)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}, {'value': '154', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=36,491,2389)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '112', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=36,491,2389)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '126', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=36,491,2389)', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '138', 'groupId': 'OG001'}, {'value': '637', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=36,491,2389)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '42', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=36,491,2389)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '90', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '111', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '61', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=36,491,2389)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}, {'value': '169', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '45', 'groupId': 'OG001'}, {'value': '257', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=36,491,2389)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=36,491,2389)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=36,491,2389)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.2564', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7361', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Naive); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '18', 'groupId': 'OG000'}, {'value': '270', 'groupId': 'OG001'}, {'value': '1411', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs7270101 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs7270101 AC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs7270101 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Argentina (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Belgium (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '54', 'groupId': 'OG002'}]}]}, {'title': 'G1, Chile (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G1, Egypt (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G1, Estonia (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, France (n=14,214,1009)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}, {'value': '157', 'groupId': 'OG002'}]}]}, {'title': 'G1, Germany (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'G1, Greece (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'G1, Italy (n=14,214,1009)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '41', 'groupId': 'OG001'}, {'value': '158', 'groupId': 'OG002'}]}]}, {'title': 'G1, Kuwait (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Latvia (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '51', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lebanon (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G1, Lithuania (n=14,214,1009)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '48', 'groupId': 'OG002'}]}]}, {'title': 'G1, Macedonia (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Mexico (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'G1, Oman (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Pakistan (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G1, Peru (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '28', 'groupId': 'OG002'}]}]}, {'title': 'G1, Portugal (n=14,214,1009)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '26', 'groupId': 'OG002'}]}]}, {'title': 'G1, Qatar (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Romania (n=14,214,1009)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '107', 'groupId': 'OG002'}]}]}, {'title': 'G1, Taiwan (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '92', 'groupId': 'OG002'}]}]}, {'title': 'G1, Turkey (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '78', 'groupId': 'OG002'}]}]}, {'title': 'G1, Slovakia (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Serbia (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, Sweden (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G1, Switzerland (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G1, Syria (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G1, United Arab Emirates (n=14,214,1009)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G1, Venezuela (n=14,214,1009)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G2, Argentina (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Belgium (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Chile (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Egypt (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Estonia (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, France (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G2, Germany (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Greece (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Italy (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '35', 'groupId': 'OG002'}]}]}, {'title': 'G2, Kuwait (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Latvia (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lebanon (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Lithuania (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, Macedonia (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Mexico (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Oman (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Pakistan (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Peru (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Portugal (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Qatar (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Romania (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Taiwan (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '67', 'groupId': 'OG002'}]}]}, {'title': 'G2, Turkey (n=1,9,130)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Slovakia (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Serbia (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Sweden (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Switzerland (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Syria (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, United Arab Emirates (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Venezuela (n=1,9,130)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Argentina (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Belgium (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Chile (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Egypt (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Estonia (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, France (n=2,18,147)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'G3, Germany (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, Greece (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'G3, Italy (n=2,18,147)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '29', 'groupId': 'OG002'}]}]}, {'title': 'G3, Kuwait (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Latvia (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lebanon (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Lithuania (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G3, Macedonia (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Mexico (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Oman (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Pakistan (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '25', 'groupId': 'OG002'}]}]}, {'title': 'G3, Peru (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Portugal (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G3, Qatar (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Romania (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Taiwan (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Turkey (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Slovakia (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Serbia (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Sweden (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Switzerland (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, Syria (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, United Arab Emirates (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Venezuela (n=2,18,147)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0097', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G1', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G2', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.9778', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G3', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G1, G2, G3) is continued onto the subsequent table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'denoms': [{'units': 'Participants', 'counts': [{'value': '18', 'groupId': 'OG000'}, {'value': '270', 'groupId': 'OG001'}, {'value': '1411', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs7270101 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs7270101 AC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs7270101 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G4, Argentina (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Belgium (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G4, Chile (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Egypt (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'G4, Estonia (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, France (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G4, Germany (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Greece (n=1,22,91)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, Italy (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '12', 'groupId': 'OG002'}]}]}, {'title': 'G4, Kuwait (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Latvia (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lebanon (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, Lithuania (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Macedonia (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Mexico (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Oman (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Pakistan (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Peru (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Portugal (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G4, Qatar (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Romania (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Taiwan (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Turkey (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Slovakia (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Serbia (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Sweden (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Switzerland (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Syria (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, United Arab Emirates (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Venezuela (n=1,22,91)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Argentina (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Belgium (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Chile (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Egypt (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Estonia (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, France (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Other, Germany (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Greece (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Italy (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Kuwait (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Latvia (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lebanon (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Lithuania (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Macedonia (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Mexico (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Oman (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Pakistan (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Peru (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'Other, Portugal (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Other, Qatar (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Romania (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Taiwan (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, Turkey (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'Other, Slovakia (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Serbia (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Sweden (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Switzerland (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Syria (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, United Arab Emirates (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Other, Venezuela (n=0,7,34)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Argentina (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '11', 'groupId': 'OG002'}]}]}, {'title': 'Total, Belgium (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '72', 'groupId': 'OG002'}]}]}, {'title': 'Total, Chile (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '27', 'groupId': 'OG002'}]}]}, {'title': 'Total, Egypt (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '37', 'groupId': 'OG002'}]}]}, {'title': 'Total, Estonia (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, France (n=18,270,1411)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '62', 'groupId': 'OG001'}, {'value': '217', 'groupId': 'OG002'}]}]}, {'title': 'Total, Germany (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '58', 'groupId': 'OG002'}]}]}, {'title': 'Total, Greece (n=18,270,1411)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '33', 'groupId': 'OG002'}]}]}, {'title': 'Total, Italy (n=18,270,1411)', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}, {'value': '235', 'groupId': 'OG002'}]}]}, {'title': 'Total, Kuwait (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Latvia (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '53', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lebanon (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '23', 'groupId': 'OG002'}]}]}, {'title': 'Total, Lithuania (n=18,270,1411)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '67', 'groupId': 'OG002'}]}]}, {'title': 'Total, Macedonia (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'Total, Mexico (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '29', 'groupId': 'OG002'}]}]}, {'title': 'Total, Oman (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Pakistan (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'Total, Peru (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '30', 'groupId': 'OG002'}]}]}, {'title': 'Total, Portugal (n=18,270,1411)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '50', 'groupId': 'OG002'}]}]}, {'title': 'Total, Qatar (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'Total, Romania (n=18,270,1411)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '107', 'groupId': 'OG002'}]}]}, {'title': 'Total, Taiwan (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '163', 'groupId': 'OG002'}]}]}, {'title': 'Total, Turkey (n=18,270,1411)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '101', 'groupId': 'OG002'}]}]}, {'title': 'Total, Slovakia (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'Total, Serbia (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, Sweden (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'Total, Switzerland (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Syria (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'Total, United Arab Emirates (n=18,270,1411)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'Total, Venezuela (n=18,270,1411)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0151', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'G4', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1052', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0007', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Pearson Chi-Square Test for differences in the ITPA distribution between the nominal categories of interest', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category. The table below (G4, Other, Total) is a continuation of the preceding table; thus, the overall number of participants analyzed reflects the total number analyzed among all genotypes (G1, G2, G3, G4, and Other).'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Type of Virological Response in the First 12 Weeks of Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '346', 'groupId': 'OG000'}, {'value': '705', 'groupId': 'OG001'}, {'value': '227', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, RVR', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '37', 'groupId': 'OG001'}, {'value': '13', 'groupId': 'OG002'}]}]}, {'title': 'G1, cEVR', 'categories': [{'measurements': [{'value': '117', 'groupId': 'OG000'}, {'value': '199', 'groupId': 'OG001'}, {'value': '44', 'groupId': 'OG002'}]}]}, {'title': 'G1, pEVR', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '147', 'groupId': 'OG001'}, {'value': '62', 'groupId': 'OG002'}]}]}, {'title': 'G1, None of above', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '184', 'groupId': 'OG001'}, {'value': '73', 'groupId': 'OG002'}]}]}, {'title': 'G2, RVR', 'categories': [{'measurements': [{'value': '46', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, cEVR', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, pEVR', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, None of above', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, RVR', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G3, cEVR', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '27', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G3, pEVR', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, None of above', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, RVR', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G4, cEVR', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, pEVR', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, None of above', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0012', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1717', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0253', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types within the first 12 weeks of treatment included rapid virological response (RVR), complete early virological response (cEVR), and partial early virological response (pEVR). RVR was defined as an undetectable HCV RNA level within the first 4 weeks, cEVR as an undetectable level within the first 12 weeks, and pEVR as a 2-log drop from Baseline to 12 weeks. Undetectable viral loads include those below the lower limit of detection (LLOD) for the assay performed, which may vary from site to site. Response categories were mutually exclusive, meaning participants could only achieve cEVR/pEVR in the absence of RVR. Participants achieving neither RVR nor cEVR/pEVR were recorded as 'none of the above.'", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Type of Virological Response in the First 12 Weeks of Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '630', 'groupId': 'OG000'}, {'value': '556', 'groupId': 'OG001'}, {'value': '92', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, RVR', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '9', 'groupId': 'OG002'}]}]}, {'title': 'G1, cEVR', 'categories': [{'measurements': [{'value': '205', 'groupId': 'OG000'}, {'value': '140', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G1, pEVR', 'categories': [{'measurements': [{'value': '88', 'groupId': 'OG000'}, {'value': '128', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'G1, None of above', 'categories': [{'measurements': [{'value': '92', 'groupId': 'OG000'}, {'value': '170', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'G2, RVR', 'categories': [{'measurements': [{'value': '50', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, cEVR', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, pEVR', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, None of above', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, RVR', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, cEVR', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, pEVR', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, None of above', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, RVR', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, cEVR', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, pEVR', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, None of above', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0330', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1595', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0412', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types within the first 12 weeks of treatment included RVR, cEVR, and pEVR. RVR was defined as an undetectable HCV RNA level within the first 4 weeks, cEVR as an undetectable level within the first 12 weeks, and pEVR as a 2-log drop from Baseline to 12 weeks. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive, meaning participants could only achieve cEVR/pEVR in the absence of RVR. Participants achieving neither RVR nor cEVR/pEVR were recorded as 'none of the above.'", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Type of Virological Response at End of Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '412', 'groupId': 'OG000'}, {'value': '773', 'groupId': 'OG001'}, {'value': '244', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Undetectable', 'categories': [{'measurements': [{'value': '194', 'groupId': 'OG000'}, {'value': '297', 'groupId': 'OG001'}, {'value': '79', 'groupId': 'OG002'}]}]}, {'title': 'G1, Detectable', 'categories': [{'measurements': [{'value': '62', 'groupId': 'OG000'}, {'value': '313', 'groupId': 'OG001'}, {'value': '125', 'groupId': 'OG002'}]}]}, {'title': 'G2, Undetectable', 'categories': [{'measurements': [{'value': '73', 'groupId': 'OG000'}, {'value': '24', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G2, Detectable', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Undetectable', 'categories': [{'measurements': [{'value': '43', 'groupId': 'OG000'}, {'value': '48', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'G3, Detectable', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Undetectable', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '29', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G4, Detectable', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '32', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0421', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7658', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2950', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types at the end of treatment included undetectable and detectable HCV RNA level. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Type of Virological Response at End of Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '718', 'groupId': 'OG000'}, {'value': '614', 'groupId': 'OG001'}, {'value': '97', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Undetectable', 'categories': [{'measurements': [{'value': '326', 'groupId': 'OG000'}, {'value': '222', 'groupId': 'OG001'}, {'value': '22', 'groupId': 'OG002'}]}]}, {'title': 'G1, Detectable', 'categories': [{'measurements': [{'value': '161', 'groupId': 'OG000'}, {'value': '279', 'groupId': 'OG001'}, {'value': '60', 'groupId': 'OG002'}]}]}, {'title': 'G2, Undetectable', 'categories': [{'measurements': [{'value': '82', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G2, Detectable', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Undetectable', 'categories': [{'measurements': [{'value': '59', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Detectable', 'categories': [{'measurements': [{'value': '18', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Undetectable', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Detectable', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '20', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0827', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7817', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1986', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types at the end of treatment included undetectable and detectable HCV RNA level. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site.', 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs12979860 by Overall Virological Response Type and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '474', 'groupId': 'OG000'}, {'value': '891', 'groupId': 'OG001'}, {'value': '290', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs12979860 CC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs12979860 TC', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs12979860 TT', 'description': "Treatment-experienced participants with CHC with IL28B polymorphism rs12979860 'TT' confirmed by blood sampling."}], 'classes': [{'title': 'G1, SVR', 'categories': [{'measurements': [{'value': '99', 'groupId': 'OG000'}, {'value': '72', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G1, Relapse', 'categories': [{'measurements': [{'value': '95', 'groupId': 'OG000'}, {'value': '221', 'groupId': 'OG001'}, {'value': '63', 'groupId': 'OG002'}]}]}, {'title': 'G1, Breakthrough', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}, {'value': '24', 'groupId': 'OG002'}]}]}, {'title': 'G1, Nonresponder', 'categories': [{'measurements': [{'value': '43', 'groupId': 'OG000'}, {'value': '253', 'groupId': 'OG001'}, {'value': '92', 'groupId': 'OG002'}]}]}, {'title': 'G1, None of above', 'categories': [{'measurements': [{'value': '37', 'groupId': 'OG000'}, {'value': '94', 'groupId': 'OG001'}, {'value': '45', 'groupId': 'OG002'}]}]}, {'title': 'G2, SVR', 'categories': [{'measurements': [{'value': '61', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G2, Relapse', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G2, Breakthrough', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Nonresponder', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, None of above', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, SVR', 'categories': [{'measurements': [{'value': '23', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, Relapse', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '24', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'G3, Breakthrough', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Nonresponder', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, None of above', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G4, SVR', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G4, Relapse', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, Breakthrough', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G4, Nonresponder', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '5', 'groupId': 'OG002'}]}]}, {'title': 'G4, None of above', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0002', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0394', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0493', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Overall virological response types included sustained virological response (SVR), relapse, and breakthrough. SVR was defined as undetectable HCV RNA level at 24 weeks post-treatment, relapse as an undetectable level at end of treatment with a detectable level at the last post-treatment measurement, and breakthrough as an undetectable level at 1 or more treatment measurements with a detectable level at end of treatment. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive. Participants with detectable HCV RNA level at 12 or more treatment measurements and who did not meet SVR criteria were considered nonresponders, and those with insufficient treatment response data were recorded as 'none of the above.'", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With IL28B Genotype rs8099917 by Overall Virological Response Type and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '831', 'groupId': 'OG000'}, {'value': '709', 'groupId': 'OG001'}, {'value': '115', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: IL28B rs8099917 TT', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TT' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: IL28B rs8099917 TG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'TG' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: IL28B rs8099917 GG', 'description': "Treatment-experienced participants with CHC with IL28B rs8099917 polymorphism 'GG' confirmed by blood sampling."}], 'classes': [{'title': 'G1, SVR', 'categories': [{'measurements': [{'value': '133', 'groupId': 'OG000'}, {'value': '46', 'groupId': 'OG001'}, {'value': '6', 'groupId': 'OG002'}]}]}, {'title': 'G1, Relapse', 'categories': [{'measurements': [{'value': '194', 'groupId': 'OG000'}, {'value': '168', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G1, Breakthrough', 'categories': [{'measurements': [{'value': '42', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}, {'value': '16', 'groupId': 'OG002'}]}]}, {'title': 'G1, Nonresponder', 'categories': [{'measurements': [{'value': '115', 'groupId': 'OG000'}, {'value': '232', 'groupId': 'OG001'}, {'value': '41', 'groupId': 'OG002'}]}]}, {'title': 'G1, None of above', 'categories': [{'measurements': [{'value': '78', 'groupId': 'OG000'}, {'value': '79', 'groupId': 'OG001'}, {'value': '19', 'groupId': 'OG002'}]}]}, {'title': 'G2, SVR', 'categories': [{'measurements': [{'value': '64', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Relapse', 'categories': [{'measurements': [{'value': '20', 'groupId': 'OG000'}, {'value': '10', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G2, Breakthrough', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G2, Nonresponder', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G2, None of above', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, SVR', 'categories': [{'measurements': [{'value': '29', 'groupId': 'OG000'}, {'value': '15', 'groupId': 'OG001'}, {'value': '2', 'groupId': 'OG002'}]}]}, {'title': 'G3, Relapse', 'categories': [{'measurements': [{'value': '27', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G3, Breakthrough', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '1', 'groupId': 'OG002'}]}]}, {'title': 'G3, Nonresponder', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '12', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G3, None of above', 'categories': [{'measurements': [{'value': '19', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'G4, SVR', 'categories': [{'measurements': [{'value': '21', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Relapse', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Breakthrough', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, Nonresponder', 'categories': [{'measurements': [{'value': '16', 'groupId': 'OG000'}, {'value': '14', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}, {'title': 'G4, None of above', 'categories': [{'measurements': [{'value': '11', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0196', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3268', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.1667', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Jonckheere-Terpstra Test for a trend of an ordinal variable across the three IL28B genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Jonckheere-Terpstra Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Overall virological response types included SVR, relapse, and breakthrough. SVR was defined as undetectable HCV RNA level at 24 weeks post-treatment, relapse as an undetectable level at end of treatment with a detectable level at the last post-treatment measurement, and breakthrough as an undetectable level at 1 or more treatment measurements with a detectable level at end of treatment. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive. Participants with detectable HCV RNA level at 12 or more treatment measurements and who did not meet SVR criteria were considered nonresponders, and those with insufficient treatment response data were recorded as 'none of the above.'", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by Incidence of Hemoglobin Drop During Prior Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '14', 'groupId': 'OG000'}, {'value': '185', 'groupId': 'OG001'}, {'value': '1112', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs1127354 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs1127354 CA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs1127354 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Yes (n=9,133,810)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '35', 'groupId': 'OG001'}, {'value': '322', 'groupId': 'OG002'}]}]}, {'title': 'G1, No (n=9,133,810)', 'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '98', 'groupId': 'OG001'}, {'value': '488', 'groupId': 'OG002'}]}]}, {'title': 'G2, Yes (n=3,27,89)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '42', 'groupId': 'OG002'}]}]}, {'title': 'G2, No (n=3,27,89)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '47', 'groupId': 'OG002'}]}]}, {'title': 'G3, Yes (n=2,20,105)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '33', 'groupId': 'OG002'}]}]}, {'title': 'G3, No (n=2,20,105)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '72', 'groupId': 'OG002'}]}]}, {'title': 'G4, Yes (n=0,2,85)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '36', 'groupId': 'OG002'}]}]}, {'title': 'G4, No (n=0,2,85)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '49', 'groupId': 'OG002'}]}]}, {'title': 'Other, Yes (n=0,3,23)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '15', 'groupId': 'OG002'}]}]}, {'title': 'Other, No (n=0,3,23)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '8', 'groupId': 'OG002'}]}]}, {'title': 'Total, Yes (n=14,185,1112)', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '46', 'groupId': 'OG001'}, {'value': '448', 'groupId': 'OG002'}]}]}, {'title': 'Total, No (n=14,185,1112)', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}, {'value': '139', 'groupId': 'OG001'}, {'value': '664', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0021', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5319', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0114', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2293', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2857', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype and hematology data were obtained from medical records. Participants with a history of a hemoglobin level less than 10 grams per deciliter (g/dL) or a drop of more than 3 g/dL at any time during prior treatment for CHC were recorded as 'yes' for this finding.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by Incidence of Hemoglobin Drop During Prior Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '13', 'groupId': 'OG000'}, {'value': '205', 'groupId': 'OG001'}, {'value': '1092', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs7270101 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs7270101 AC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs7270101 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Yes (n=10,159,783)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}, {'value': '309', 'groupId': 'OG002'}]}]}, {'title': 'G1, No (n=10,159,783)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '110', 'groupId': 'OG001'}, {'value': '474', 'groupId': 'OG002'}]}]}, {'title': 'G2, Yes (n=0,8,110)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '52', 'groupId': 'OG002'}]}]}, {'title': 'G2, No (n=0,8,110)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}, {'value': '58', 'groupId': 'OG002'}]}]}, {'title': 'G3, Yes (n=2,14,111)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '31', 'groupId': 'OG002'}]}]}, {'title': 'G3, No (n=2,14,111)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}, {'value': '80', 'groupId': 'OG002'}]}]}, {'title': 'G4, Yes (n=1,19,67)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '33', 'groupId': 'OG002'}]}]}, {'title': 'G4, No (n=1,19,67)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '16', 'groupId': 'OG001'}, {'value': '34', 'groupId': 'OG002'}]}]}, {'title': 'Other, Yes (n=0,5,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'Other, No (n=0,5,21)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}, {'value': '7', 'groupId': 'OG002'}]}]}, {'title': 'Total, Yes (n=13,205,1092)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '58', 'groupId': 'OG001'}, {'value': '439', 'groupId': 'OG002'}]}]}, {'title': 'Total, No (n=13,205,1092)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '147', 'groupId': 'OG001'}, {'value': '653', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0081', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0563', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3516', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0064', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2707', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '< 0.0001', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype and hematology data were obtained from medical records. Participants with a history of a hemoglobin level less than 10 g/dL or a drop of more than 3 g/dL at any time during prior treatment for CHC were recorded as 'yes' for this finding.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs1127354 by Erythropoietin Use During Prior Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '15', 'groupId': 'OG000'}, {'value': '225', 'groupId': 'OG001'}, {'value': '1388', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs1127354 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'AA' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs1127354 CA', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CA' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs1127354 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs1127354 polymorphism 'CC' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Yes (n=10,162,1016)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}, {'value': '103', 'groupId': 'OG002'}]}]}, {'title': 'G1, No (n=10,162,1016)', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '154', 'groupId': 'OG001'}, {'value': '913', 'groupId': 'OG002'}]}]}, {'title': 'G2, Yes (n=3,30,105)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '14', 'groupId': 'OG002'}]}]}, {'title': 'G2, No (n=3,30,105)', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '91', 'groupId': 'OG002'}]}]}, {'title': 'G3, Yes (n=2,24,137)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, No (n=2,24,137)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '24', 'groupId': 'OG001'}, {'value': '133', 'groupId': 'OG002'}]}]}, {'title': 'G4, Yes (n=0,5,106)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}, {'value': '18', 'groupId': 'OG002'}]}]}, {'title': 'G4, No (n=0,5,106)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '88', 'groupId': 'OG002'}]}]}, {'title': 'Other, Yes (n=0,4,24)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, No (n=0,4,24)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '4', 'groupId': 'OG001'}, {'value': '21', 'groupId': 'OG002'}]}]}, {'title': 'Total, Yes (n=15,225,1388)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}, {'value': '142', 'groupId': 'OG002'}]}]}, {'title': 'Total, No (n=15,225,1388)', 'categories': [{'measurements': [{'value': '14', 'groupId': 'OG000'}, {'value': '212', 'groupId': 'OG001'}, {'value': '1246', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.0634', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.7176', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3944', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.8610', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4543', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.0406', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records. Past medication use was obtained from medical records and/or participant interview at the Study Visit. Participants with a history of erythropoietin use during prior treatment for CHC were recorded as 'yes' for this finding.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With ITPA Genotype rs7270101 by Erythropoietin Use During Prior Treatment and HCV RNA Genotype', 'denoms': [{'units': 'Participants', 'counts': [{'value': '17', 'groupId': 'OG000'}, {'value': '257', 'groupId': 'OG001'}, {'value': '1354', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Experienced: ITPA rs7270101 CC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'CC' confirmed by blood sampling."}, {'id': 'OG001', 'title': 'Experienced: ITPA rs7270101 AC', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AC' confirmed by blood sampling."}, {'id': 'OG002', 'title': 'Experienced: ITPA rs7270101 AA', 'description': "Treatment-experienced participants with CHC with ITPA rs7270101 polymorphism 'AA' confirmed by blood sampling."}], 'classes': [{'title': 'G1, Yes (n=14,206,969)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '19', 'groupId': 'OG001'}, {'value': '91', 'groupId': 'OG002'}]}]}, {'title': 'G1, No (n=14,206,969)', 'categories': [{'measurements': [{'value': '12', 'groupId': 'OG000'}, {'value': '187', 'groupId': 'OG001'}, {'value': '878', 'groupId': 'OG002'}]}]}, {'title': 'G2, Yes (n=0,9,128)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G2, No (n=0,9,128)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '9', 'groupId': 'OG001'}, {'value': '111', 'groupId': 'OG002'}]}]}, {'title': 'G3, Yes (n=2,17,144)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '4', 'groupId': 'OG002'}]}]}, {'title': 'G3, No (n=2,17,144)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '17', 'groupId': 'OG001'}, {'value': '140', 'groupId': 'OG002'}]}]}, {'title': 'G4, Yes (n=1,20,90)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}, {'value': '17', 'groupId': 'OG002'}]}]}, {'title': 'G4, No (n=1,20,90)', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '18', 'groupId': 'OG001'}, {'value': '73', 'groupId': 'OG002'}]}]}, {'title': 'Other, Yes (n=0,5,23)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '3', 'groupId': 'OG002'}]}]}, {'title': 'Other, No (n=0,5,23)', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}, {'value': '20', 'groupId': 'OG002'}]}]}, {'title': 'Total, Yes (n=17,257,1354)', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '21', 'groupId': 'OG001'}, {'value': '132', 'groupId': 'OG002'}]}]}, {'title': 'Total, No (n=17,257,1354)', 'categories': [{'measurements': [{'value': '15', 'groupId': 'OG000'}, {'value': '236', 'groupId': 'OG001'}, {'value': '1222', 'groupId': 'OG002'}]}]}], 'analyses': [{'pValue': '0.8234', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G1', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2427', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G2', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.4805', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G3', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.2901', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'G4', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.3927', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Other genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}, {'pValue': '0.5769', 'groupIds': ['OG000', 'OG001', 'OG002'], 'ciNumSides': 'TWO_SIDED', 'pValueComment': 'Cochran-Armitage Trend Test for a trend in binomial proportions across the three ITPA genotype categories', 'groupDescription': 'Total genotypes', 'statisticalMethod': 'Cochran-Armitage Trend Test', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER', 'testedNonInferiority': False}], 'paramType': 'NUMBER', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records. Past medication use was obtained from medical records and/or participant interview at the Study Visit. Participants with a history of erythropoietin use during prior treatment for CHC were recorded as 'yes' for this finding.", 'unitOfMeasure': 'participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Core Analysis Population (Treatment-Experienced); n = number of participants analyzed within each HCV RNA genotype category.'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Participants With Chronic Hepatitis C (CHC)', 'description': 'Both treatment-naive and treatment-experienced participants with CHC were enrolled in this prospective, interventional Phase 4 study.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '4766'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '4732'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '34'}]}], 'dropWithdraws': [{'type': 'Withdrawal by Subject', 'reasons': [{'groupId': 'FG000', 'numSubjects': '7'}]}, {'type': 'Participant Refused Sample Collection', 'reasons': [{'groupId': 'FG000', 'numSubjects': '18'}]}, {'type': 'Sample not Collected by Mistake', 'reasons': [{'groupId': 'FG000', 'numSubjects': '2'}]}, {'type': 'Lost to Follow-up', 'reasons': [{'groupId': 'FG000', 'numSubjects': '5'}]}, {'type': 'Other', 'reasons': [{'groupId': 'FG000', 'numSubjects': '2'}]}]}]}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '4616', 'groupId': 'BG000'}]}], 'groups': [{'id': 'BG000', 'title': 'Participants With CHC', 'description': 'Both treatment-naive and treatment-experienced participants with CHC were enrolled in this prospective, interventional Phase 4 study.'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '49.1', 'spread': '12.87', 'groupId': 'BG000'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '2043', 'groupId': 'BG000'}]}, {'title': 'Male', 'measurements': [{'value': '2573', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}], 'populationDescription': 'Core Analysis Population: All participants enrolled who had a blood sample drawn for genotyping with available data for the primary variables, and who met all eligibility criteria for analysis.'}}, 'protocolSection': {'designModule': {'phases': ['PHASE4'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 4766}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2011-08'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2015-08', 'completionDateStruct': {'date': '2013-10', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2015-08-12', 'studyFirstSubmitDate': '2012-08-24', 'resultsFirstSubmitDate': '2015-05-21', 'studyFirstSubmitQcDate': '2012-08-29', 'lastUpdatePostDateStruct': {'date': '2015-08-26', 'type': 'ESTIMATED'}, 'resultsFirstSubmitQcDate': '2015-05-21', 'studyFirstPostDateStruct': {'date': '2012-08-30', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2015-06-08', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2013-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Number of Participants With Interleukin 28B (IL28B) Genotype rs12979860 by Cirrhosis Status and Hepatitis C Virus (HCV) Ribonucleic Acid (RNA) Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1 (single study visit)', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype (Genotype 1 \\[G1\\], Genotype 2 \\[G2\\], Genotype 3 \\[G3\\], Genotype 4 \\[G4\\], and all other genotypes \\[Other\\]) and cirrhosis status ('Cirrhosis/transition to cirrhosis' or 'No cirrhosis') were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable."}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Cirrhosis Status and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Cirrhosis Status and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Cirrhosis Status and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and cirrhosis status were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable."}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable."}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable."}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage ('Cirrhotic,' 'Transition to cirrhosis,' 'Advanced fibrosis noncirrhotic,' 'Mild/minimal fibrosis,' and 'No fibrosis') were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using these five categories and captured prior to treatment, if applicable."}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Fibrosis Stage and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver fibrosis stage (Stage F0, Stage F1, Stage F2, Stage F3, or Stage F4) were obtained from medical records. Liver fibrosis stage was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Mean FibroScan Values by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kilopascals (kPa).'}, {'measure': 'Mean FibroScan Values by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.'}, {'measure': 'Mean FibroScan Values by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.'}, {'measure': 'Mean FibroScan Values by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver elastography (FibroScan) were obtained from medical records. FibroScan values were based upon previous noninvasive assessment captured prior to treatment, if applicable. Mean FibroScan values were determined by averaging the values of all participants within each arm and expressed in kPa.'}], 'secondaryOutcomes': [{'measure': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by METAVIR Liver Inflammation Grade and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and liver inflammation grade (Grade A0, Grade A1, Grade A2, or Grade A3) were obtained from medical records. Liver inflammation grade was based upon previous biopsy using the METAVIR scoring system and captured prior to treatment, if applicable.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Gender: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including gender, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Gender: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including gender, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Gender: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including gender, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Gender: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including gender, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Ethnic Origin: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including self-reported ethnic origin, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Ethnic Origin: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including self-reported ethnic origin, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Ethnic Origin: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including self-reported ethnic origin, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Ethnic Origin: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including self-reported ethnic origin, were obtained from medical records and/or participant interview at the Study Visit.'}, {'measure': 'Mean Body Weight by IL28B Genotype rs12979860: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Mean body weight was calculated by averaging the values of all participants within each arm and expressed in kilograms (kg).'}, {'measure': 'Mean Body Weight by IL28B Genotype rs12979860: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Mean body weight was calculated by averaging the values of all participants within each arm and expressed in kg.'}, {'measure': 'Mean Body Weight by IL28B Genotype rs8099917: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Mean body weight was calculated by averaging the values of all participants within each arm and expressed in kg.'}, {'measure': 'Mean Body Weight by IL28B Genotype rs8099917: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Mean body weight was calculated by averaging the values of all participants within each arm and expressed in kg.'}, {'measure': 'Mean Body Mass Index (BMI) by IL28B Genotype rs12979860: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including height and pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Each participant's BMI was calculated as weight divided by height-squared, expressed in kilograms per meter-squared (kg/m\\^2), and mean BMI was calculated by averaging the values of all participants within each arm."}, {'measure': 'BMI by IL28B Genotype rs12979860: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including height and pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Each participant's BMI was calculated as weight divided by height-squared, expressed in kg/m\\^2, and mean BMI was calculated by averaging the values of all participants within each arm."}, {'measure': 'BMI by IL28B Genotype rs8099917: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including height and pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Each participant's BMI was calculated as weight divided by height-squared, expressed in kg/m\\^2, and mean BMI was calculated by averaging the values of all participants within each arm."}, {'measure': 'BMI by IL28B Genotype rs8099917: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Demographic characteristics, including height and pre-treatment body weight, were obtained from medical records and/or participant interview at the Study Visit. Each participant's BMI was calculated as weight divided by height-squared, expressed in kg/m\\^2, and mean BMI was calculated by averaging the values of all participants within each arm."}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records.'}, {'measure': 'Mean HCV RNA Level by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 international units per milliliter (log10 IU/mL).'}, {'measure': 'Mean HCV RNA Level by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.'}, {'measure': 'Mean HCV RNA Level by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.'}, {'measure': 'Mean HCV RNA Level by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA level was obtained from medical records. Mean HCV RNA level was calculated by averaging the values of all participants within each arm and expressed in log10 IU/mL.'}, {'measure': 'Mean Alanine Aminotransferase (ALT) Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 international units per liter \\[IU/L\\] for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean ALT Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean ALT Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean ALT Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. ALT level was obtained from medical records captured prior to treatment, if applicable. Each participant's ALT ratio was calculated as ALT level divided by the upper limit of normal (55 IU/L for males and 30 IU/L for females). Mean ALT ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean Aspartate Aminotransferase (AST) Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean AST Ratio by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean AST Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean AST Ratio by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. AST level was obtained from medical records captured prior to treatment, if applicable. Each participant's AST ratio was calculated as AST level divided by the upper limit of normal (40 IU/L for males and 25 IU/L for females). Mean AST ratio was calculated by averaging the values of all participants within each arm."}, {'measure': 'Mean Platelet Count by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells per liter (10\\^9 cells/L).'}, {'measure': 'Mean Platelet Count by IL28B Genotype rs12979860 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.'}, {'measure': 'Mean Platelet Count by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.'}, {'measure': 'Mean Platelet Count by IL28B Genotype rs8099917 and HCV RNA Genotype: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. Platelet count was obtained from medical records captured prior to treatment, if applicable. Mean platelet count was calculated by averaging the values of all participants within each arm and expressed in 10\\^9 cells/L.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Region: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Region: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Region: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Region: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by IL28B Genotype rs8099917 Category: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by IL28B Genotype rs8099917 Category: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype.'}, {'measure': 'Number of Participants With Inosine Triphosphatase (ITPA) Genotype rs7270101 by ITPA Genotype rs1127354 Category: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by ITPA Genotype rs1127354 Category: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Region: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Region: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Region: Treatment-Naive', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Region: Treatment-Experienced', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and geographic region of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Naive (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Naive (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Experienced (Table 1 of 2 [G1, G2, G3])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by HCV RNA Genotype and Country: Treatment-Experienced (Table 2 of 2 [G4, Other, Total])', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records, and country of study site was documented during intake/enrollment.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Type of Virological Response in the First 12 Weeks of Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types within the first 12 weeks of treatment included rapid virological response (RVR), complete early virological response (cEVR), and partial early virological response (pEVR). RVR was defined as an undetectable HCV RNA level within the first 4 weeks, cEVR as an undetectable level within the first 12 weeks, and pEVR as a 2-log drop from Baseline to 12 weeks. Undetectable viral loads include those below the lower limit of detection (LLOD) for the assay performed, which may vary from site to site. Response categories were mutually exclusive, meaning participants could only achieve cEVR/pEVR in the absence of RVR. Participants achieving neither RVR nor cEVR/pEVR were recorded as 'none of the above.'"}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Type of Virological Response in the First 12 Weeks of Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types within the first 12 weeks of treatment included RVR, cEVR, and pEVR. RVR was defined as an undetectable HCV RNA level within the first 4 weeks, cEVR as an undetectable level within the first 12 weeks, and pEVR as a 2-log drop from Baseline to 12 weeks. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive, meaning participants could only achieve cEVR/pEVR in the absence of RVR. Participants achieving neither RVR nor cEVR/pEVR were recorded as 'none of the above.'"}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Type of Virological Response at End of Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types at the end of treatment included undetectable and detectable HCV RNA level. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site.'}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Type of Virological Response at End of Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': 'Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Virological response types at the end of treatment included undetectable and detectable HCV RNA level. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site.'}, {'measure': 'Number of Participants With IL28B Genotype rs12979860 by Overall Virological Response Type and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Overall virological response types included sustained virological response (SVR), relapse, and breakthrough. SVR was defined as undetectable HCV RNA level at 24 weeks post-treatment, relapse as an undetectable level at end of treatment with a detectable level at the last post-treatment measurement, and breakthrough as an undetectable level at 1 or more treatment measurements with a detectable level at end of treatment. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive. Participants with detectable HCV RNA level at 12 or more treatment measurements and who did not meet SVR criteria were considered nonresponders, and those with insufficient treatment response data were recorded as 'none of the above.'"}, {'measure': 'Number of Participants With IL28B Genotype rs8099917 by Overall Virological Response Type and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype and virological response to prior treatment were obtained from medical records. Overall virological response types included SVR, relapse, and breakthrough. SVR was defined as undetectable HCV RNA level at 24 weeks post-treatment, relapse as an undetectable level at end of treatment with a detectable level at the last post-treatment measurement, and breakthrough as an undetectable level at 1 or more treatment measurements with a detectable level at end of treatment. Undetectable viral loads include those below the LLOD for the assay performed, which may vary from site to site. Response categories were mutually exclusive. Participants with detectable HCV RNA level at 12 or more treatment measurements and who did not meet SVR criteria were considered nonresponders, and those with insufficient treatment response data were recorded as 'none of the above.'"}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by Incidence of Hemoglobin Drop During Prior Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype and hematology data were obtained from medical records. Participants with a history of a hemoglobin level less than 10 grams per deciliter (g/dL) or a drop of more than 3 g/dL at any time during prior treatment for CHC were recorded as 'yes' for this finding."}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by Incidence of Hemoglobin Drop During Prior Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype and hematology data were obtained from medical records. Participants with a history of a hemoglobin level less than 10 g/dL or a drop of more than 3 g/dL at any time during prior treatment for CHC were recorded as 'yes' for this finding."}, {'measure': 'Number of Participants With ITPA Genotype rs1127354 by Erythropoietin Use During Prior Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records. Past medication use was obtained from medical records and/or participant interview at the Study Visit. Participants with a history of erythropoietin use during prior treatment for CHC were recorded as 'yes' for this finding."}, {'measure': 'Number of Participants With ITPA Genotype rs7270101 by Erythropoietin Use During Prior Treatment and HCV RNA Genotype', 'timeFrame': 'Study Visit 1', 'description': "Participants underwent blood sampling at the Study Visit to determine ITPA genotype. HCV RNA genotype was obtained from medical records. Past medication use was obtained from medical records and/or participant interview at the Study Visit. Participants with a history of erythropoietin use during prior treatment for CHC were recorded as 'yes' for this finding."}]}, 'conditionsModule': {'conditions': ['Hepatitis C, Chronic']}, 'descriptionModule': {'briefSummary': 'This multicenter study will evaluate the correlation of interleukin 28B (IL28B) genotypes with disease characteristics and demographics in treatment-naïve and treatment-experienced chronic hepatitis C patients, including patients with HIV co-infection. There will be a single study visit for testing.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Adult (according to local legislation) male or female patient\n* Chronic hepatitis C (CHC)\n* Patients naïve to CHC treatment or patients who received prior interferon-based therapy for CHC for whom data on treatment received and treatment outcome is available; information on fibrosis stage prior to previous treatment is also required\n\nExclusion Criteria:\n\n* Co-infection with hepatitis B\n* History or evidence of decompensated liver disease\n* History of major organ transplantation with an existing functional graft (including liver transplantation)\n* End stage renal disease'}, 'identificationModule': {'nctId': 'NCT01675427', 'briefTitle': 'A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C', 'organization': {'class': 'INDUSTRY', 'fullName': 'Hoffmann-La Roche'}, 'officialTitle': 'An International, Multi-Center Study Evaluating the Correlation of IL28B Genotypes With Patient Demographics and Disease Characteristics in Patients With Chronic Hepatitis C', 'orgStudyIdInfo': {'id': 'MV25600'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Chronic hepatitis C patients', 'interventionNames': ['Other: Interleukin 28B testing']}], 'interventions': [{'name': 'Interleukin 28B testing', 'type': 'OTHER', 'description': 'Blood sampling for ILB28 genotyping', 'armGroupLabels': ['Chronic hepatitis C patients']}]}, 'contactsLocationsModule': {'locations': [{'zip': '22304', 'city': 'Alexandria', 'state': 'Virginia', 'country': 'United States', 'geoPoint': {'lat': 38.80484, 'lon': -77.04692}}, {'zip': 'CP B1704 ETD', 'city': 'Buenos Aires', 'country': 'Argentina', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': '7600', 'city': 'Mar del Plata', 'country': 'Argentina', 'geoPoint': {'lat': -38.00042, 'lon': -57.5562}}, {'zip': '2060', 'city': 'Antwerp', 'country': 'Belgium', 'geoPoint': {'lat': 51.22047, 'lon': 4.40026}}, {'zip': '8000', 'city': 'Bruges', 'country': 'Belgium', 'geoPoint': {'lat': 51.20892, 'lon': 3.22424}}, {'zip': '1000', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': '1020', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': '1070', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': '1090', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': '1180', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': '1190', 'city': 'Brussels', 'country': 'Belgium', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': 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50.94653, 'lon': 3.12269}}, {'zip': '8330024', 'city': 'Santiago', 'country': 'Chile', 'geoPoint': {'lat': -33.45694, 'lon': -70.64827}}, {'zip': '8380456', 'city': 'Santiago', 'country': 'Chile', 'geoPoint': {'lat': -33.45694, 'lon': -70.64827}}, {'zip': '11559', 'city': 'Cairo', 'country': 'Egypt', 'geoPoint': {'lat': 30.06263, 'lon': 31.24967}}, {'city': 'Cairo', 'country': 'Egypt', 'geoPoint': {'lat': 30.06263, 'lon': 31.24967}}, {'city': 'Giza', 'country': 'Egypt', 'geoPoint': {'lat': 30.00944, 'lon': 31.20861}}, {'zip': '32511', 'city': 'Menoufiya', 'country': 'Egypt'}, {'city': 'Tanta', 'country': 'Egypt', 'geoPoint': {'lat': 30.78847, 'lon': 31.00192}}, {'zip': '31025', 'city': 'Kohtla-Järve', 'country': 'Estonia', 'geoPoint': {'lat': 59.39861, 'lon': 27.27306}}, {'zip': '80010', 'city': 'Pärnu', 'country': 'Estonia', 'geoPoint': {'lat': 58.38588, 'lon': 24.49711}}, {'zip': '10138', 'city': 'Tallinn', 'country': 'Estonia', 'geoPoint': {'lat': 59.43696, 'lon': 24.75353}}, 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