Ignite Creation Date:
2025-12-25 @ 5:08 AM
Ignite Modification Date:
2025-12-26 @ 4:12 AM
Study NCT ID:
NCT04063527
Status:
RECRUITING
Last Update Posted:
2019-08-30
First Post:
2019-08-16
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Phase III Trial of Stage I Ovarian Cancer After Surgery
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000077216', 'term': 'Carcinoma, Ovarian Epithelial'}], 'ancestors': [{'id': 'D002277', 'term': 'Carcinoma'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D010051', 'term': 'Ovarian Neoplasms'}, {'id': 'D004701', 'term': 'Endocrine Gland Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D010049', 'term': 'Ovarian Diseases'}, {'id': 'D000291', 'term': 'Adnexal Diseases'}, {'id': 'D005831', 'term': 'Genital Diseases, Female'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D005833', 'term': 'Genital Neoplasms, Female'}, {'id': 'D014565', 'term': 'Urogenital Neoplasms'}, {'id': 'D000091662', 'term': 'Genital Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}, {'id': 'D006058', 'term': 'Gonadal Disorders'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D017024', 'term': 'Chemotherapy, Adjuvant'}, {'id': 'D017239', 'term': 'Paclitaxel'}, {'id': 'D016190', 'term': 'Carboplatin'}], 'ancestors': [{'id': 'D003131', 'term': 'Combined Modality Therapy'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D004358', 'term': 'Drug Therapy'}, {'id': 'D043823', 'term': 'Taxoids'}, {'id': 'D043822', 'term': 'Cyclodecanes'}, {'id': 'D003516', 'term': 'Cycloparaffins'}, {'id': 'D006840', 'term': 'Hydrocarbons, Alicyclic'}, {'id': 'D006844', 'term': 'Hydrocarbons, Cyclic'}, {'id': 'D006838', 'term': 'Hydrocarbons'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D004224', 'term': 'Diterpenes'}, {'id': 'D013729', 'term': 'Terpenes'}, {'id': 'D056831', 'term': 'Coordination Complexes'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 360}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2012-07-20', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2019-08', 'completionDateStruct': {'date': '2030-02-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2019-08-28', 'studyFirstSubmitDate': '2019-08-16', 'studyFirstSubmitQcDate': '2019-08-20', 'lastUpdatePostDateStruct': {'date': '2019-08-30', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2019-08-21', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2029-10-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Overall survival', 'timeFrame': 'From date of randomization until the date of death from any cause, assessed up to 60 months', 'description': '1. In surviving patients, cut off will be on the last date the patient is confirmed to be alive.\n2. If a patient is lost to follow-up, cut off will be on the last date the patient is confirmed to be alive before being lost to follow-up.'}], 'secondaryOutcomes': [{'measure': 'Relapse-free survival', 'timeFrame': 'From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 60 months', 'description': '1. If relapse is diagnosed through imaging, it is considered an event on the "test date" on which a "definite diagnosis" is obtained and not the test date that showed a "suspected relapse on an image." If a relapse is clinically diagnosed, not just through imaging, it is considered an event on the date on which relapse is diagnosed.\n2. Progression observed by CA-125 only shall not be handled as an event in this study.'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['epithelial ovarian cancer', 'FIGO stage I', 'staging surgery', 'adjuvant chemotherapy'], 'conditions': ['Epithelial Ovarian Cancer']}, 'descriptionModule': {'briefSummary': 'To compare the Overall survival of adjuvant chemotherapy versus observation in stage I epithelial ovarian cancer after comprehensive staging surgery', 'detailedDescription': 'Based on the following adjustment factors, patients will be randomly assigned in a 1:1 ratio to adjuvant chemotherapy or observation groups.\n\n1. Histologic type: clear cell adenocarcinoma/mucinous adenocarcinoma vs. serous adenocarcinoma/other histologic types\n2. Facility where a subject is enrolled\n3. International Federation of Gynecology and Obstetrics(FIGO) clinical staging: Stage Ia/ Ib vs. Stage Ic(b)\n\nGroup A: adjuvant chemotherapy group (standard treatment group):\n\nWhile one of the following treatments will be performed, the number of cycles is entrusted to the treatment policy of each facility.\n\nPaclitaxel plus Carboplatin (TC) therapy; Paclitaxel (PTX) 175 mg/m2 + Carboplatin(CBDCA) area under curve(AUC) 6 q3weeks day1, 3 to 6 cycles Docetaxel plus Carboplatin (DC) therapy; Docetaxel(DTX) 70 mg/m2 + CBDCA AUC 6 q3weeks day1, 3 to 6 cycles\n\nAfter the start of TC therapy, switching from PTX to DTX due to an adverse event is permitted.\n\nGroup B: observation group (study treatment group): Observation only, no adjuvant chemotherapy administered.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '20 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Patients with a diagnosis of histopathologically epithelial ovarian cancer\n2. FIGO Stages Ia(Grade2/3, clear cell carcinoma), Ib(Grade2/3, clear cell carcinoma) and Ic(b)(all degree of differentiation and all histologic type)\n3. Patients with a diagnosis of advanced stage by comprehensive staging or restaging laparotomy.\n4. Patients who received comprehensive staging surgery (basic surgical techniques (total hysterectomy, bilateral salpingo-oophorectomy, and omentectomy) as well as peritoneal cytology, multiple biopsies of the peritoneum (\\[Peritoneal biopsy\\] see details below), retroperitoneal lymph node dissection (see details below \\[Retroperitoneal lymph node dissection\\]).\n\n However, for the following cases, it is eligible as a condition to record on the official document.\n * Peritoneal biopsy: peritoneal metastasis is not recognized by macroscopic and palpation in the stipulated site, and the case that biopsy has not been performed.\n * Retroperitoneal lymph node dissection: the case that lymph nodes of the stipulated range has been dissected however the prescribed number has not been reached.\n5. Age: 20 or older\n6. Performance status (PS):0-1\n7. Case with initial therapy for postoperative primary lesion\n8. Patient possible to receive the first study treatment within 8 weeks after the comprehensive staging surgery\n9. Reasonable organ function\n10. Patient must have signed informed consent.\n\nExclusion Criteria:\n\n1. FIGO Stages Ic(a), Ic(1) and Ic(2)\n2. Patients containing sarcoma elements\n3. Patients with any signs of interstitial pneumonia or pulmonary fibrosis by chest radiography and CT\n4. Patients with serious complications\n5. Patients with active infection\n6. Patients with intestinal paralysis or intestinal obstruction\n7. Patients who have a synchronous malignancy or who have been progression-free less than 5 years for a metachronous malignancy\n8. Patients with previous chemotherapy or radiation therapy\n9. Patients with serious drug hypersensitivity\n10. Patients with peripheral motor/sensory neuropathy \\[grade2,3,4 Common Terminology Criteria for Adverse Events (CTCAE) 4.0\\]\n11. Patients who have had a hypersensitivity reaction to polyoxyethylated or hydrogenated castor oil\n12. Patients with positive HBsAg. Patients with more than 2.1 log/copies ml based on fixed Hepatitis B virus (HBV)-DNA who are positive with either antigen-positive Hepatitis B (HBs), anti-hepatitis B core antigen or anti-hepatitis B surface antigen.\n13. Patients who are inappropriate to enter this study with any safety reasons, judged by the treating physician'}, 'identificationModule': {'nctId': 'NCT04063527', 'briefTitle': 'Phase III Trial of Stage I Ovarian Cancer After Surgery', 'organization': {'class': 'OTHER', 'fullName': 'Japanese Gynecologic Oncology Group'}, 'officialTitle': 'Randomized Phase III Trial of the Need for Adjuvant Chemotherapy in Stage I Epithelial Ovarian Cancer After Comprehensive Staging Surgery', 'orgStudyIdInfo': {'id': 'JGOG3020'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Standard therapy', 'description': 'combination of paclitaxel and carboplatin', 'interventionNames': ['Drug: adjuvant chemotherapy']}, {'type': 'NO_INTERVENTION', 'label': 'Observation', 'description': 'Observation'}], 'interventions': [{'name': 'adjuvant chemotherapy', 'type': 'DRUG', 'otherNames': ['paclitaxel and carboplatin'], 'description': 'combination of paclitaxel and carboplatin', 'armGroupLabels': ['Standard therapy']}]}, 'contactsLocationsModule': {'locations': [{'zip': '480-1195', 'city': 'Nagakute-shi', 'state': 'Aichi-ken', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Taiki Ueno', 'role': 'CONTACT', 'email': 'garuboxer@gmail.com', 'phone': '81-561-62-3311'}], 'facility': 'Aichi Medical University Hospital'}, {'zip': '489-8642', 'city': 'Seto-shi', 'state': 'Aichi-ken', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hidekazu Asai', 'role': 'CONTACT', 'email': 'hide.asai1990@tosei.or.jp', 'phone': '81-561-82-5101'}], 'facility': 'Tosei General Hospital'}, {'zip': '470-1193', 'city': 'Toyoake-shi', 'state': 'Aichi-ken', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takuma Fujii', 'role': 'CONTACT', 'email': 'fujiit44@gmail.com', 'phone': '81-562-93-9294'}], 'facility': 'Fujita Health University Hospital'}, {'zip': '036-8563', 'city': 'Hirosaki-shi', 'state': 'Aomori', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Yoshihito Yokoyama', 'role': 'CONTACT', 'email': 'yokoyama@hirosaki-u.ac.jp', 'phone': '81-172-39-5107'}], 'facility': 'Hirosaki University School of Medicine & Hospital'}, {'zip': '277-8567', 'city': 'Kashiwa-shi', 'state': 'Chiba', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hirokuni Takano', 'role': 'CONTACT', 'email': 'hirokuni@jikei.ac.jp', 'phone': '81-4-7164-1111'}], 'facility': 'The Jikei University School of Medicine Kashiwa Hospital'}, {'zip': '277-8577', 'city': 'Kashiwa-shi', 'state': 'Chiba', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hiroshi Tanabe', 'role': 'CONTACT', 'email': 'htanabe@east.ncc.go.jp', 'phone': '81-4-7133-1111'}], 'facility': 'National Cancer Center Hospital East'}, {'zip': '791-0295', 'city': 'Onsen-gun', 'state': 'Ehime', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takashi Matsumoto', 'role': 'CONTACT', 'email': 'matsugen@m.ehime-u.ac.jp', 'phone': '81-89-960-5379'}], 'facility': 'Ehime University Hospital'}, {'zip': '810-8563', 'city': 'Fukuoka', 'state': 'Fukuoka', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Yasuyuki Hasuo', 'role': 'CONTACT', 'email': 'hasuo.yasuyuki.ab@mail.hosp.go.jp', 'phone': '81-92-852-0700'}], 'facility': 'Kyusyu Medical Center', 'geoPoint': {'lat': 33.6, 'lon': 130.41667}}, {'zip': '811-1395', 'city': 'Fukuoka', 'state': 'Fukuoka', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Masao Okadome', 'role': 'CONTACT', 'email': 'okadome.m@nk-cc.go.jp', 'phone': '81-92-541-3231'}], 'facility': 'Kyusyu Cancer Center', 'geoPoint': {'lat': 33.6, 'lon': 130.41667}}, {'zip': '812-8582', 'city': 'Fukuoka', 'state': 'Fukuoka', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Kiyoko Kato', 'role': 'CONTACT', 'email': 'kkato@med.kyushu-u.ac.jp', 'phone': '81-92-641-1151'}], 'facility': 'Kyushu University Hospital', 'geoPoint': {'lat': 33.6, 'lon': 130.41667}}, {'zip': '830-0011', 'city': 'Kurume-shi', 'state': 'Fukuoka', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Kimio Ushijima', 'role': 'CONTACT', 'email': 'kimi@med.kurume-u.ac.jp', 'phone': '81-942-31-7573'}], 'facility': 'Kurume University Hospital'}, {'zip': '501-1194', 'city': 'Gifu', 'state': 'Gifu', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Kenichiro Morishige', 'role': 'CONTACT', 'email': 'mken@gifu-u.ac.jp', 'phone': '81-58-230-6349'}], 'facility': 'Gifu University Hospital', 'geoPoint': {'lat': 35.42291, 'lon': 136.76039}}, {'zip': '371-8511', 'city': 'Maebashi', 'state': 'Gunma', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takashi Hirakawa', 'role': 'CONTACT', 'email': 'thira@gunma-u.ac.jp', 'phone': '81-27-220-7111'}], 'facility': 'Gunma University Hospital', 'geoPoint': {'lat': 36.4, 'lon': 139.08333}}, {'zip': '373-8550', 'city': 'Ōta', 'state': 'Gunma', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Kazuto Nakamura', 'role': 'CONTACT', 'email': 'nkazuto@gunma-cc.jp', 'phone': '81-276-38-0771'}], 'facility': 'Gunma Prefectural Cancer Center', 'geoPoint': {'lat': 36.3, 'lon': 139.36667}}, {'zip': '738-8503', 'city': 'Hatsukaichi-shi', 'state': 'Hiroshima', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Yoshinobu Nakanishi', 'role': 'CONTACT', 'email': 'y-nakanishi@do7.enjoy.ne.jp', 'phone': '81-829-36-3111'}], 'facility': 'JA Hiroshima General Hospital'}, {'zip': '730-8518', 'city': 'Hiroshima', 'state': 'Hiroshima', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Junichi Kodama', 'role': 'CONTACT', 'email': 'kodama@cc.okayama-u.ac.jp', 'phone': '81-82-221-2291'}], 'facility': 'Hiroshima City Hiroshima Citizens Hospital', 'geoPoint': {'lat': 34.4, 'lon': 132.45}}, {'zip': '734-8530', 'city': 'Hiroshima', 'state': 'Hiroshima', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Yuko Shiroyama', 'role': 'CONTACT', 'email': 'y-shiroyama73182@pref.hiroshima.lg.jp', 'phone': '81-82-254-1818'}], 'facility': 'Hiroshima Prefectural Hospital', 'geoPoint': {'lat': 34.4, 'lon': 132.45}}, {'zip': '728-8502', 'city': 'Miyoshi-shi', 'state': 'Hiroshima', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takefumi Akagi', 'role': 'CONTACT', 'email': 'keioka16@gmail.com', 'phone': '81-824-65-0101'}], 'facility': 'Miyoshi Central Hospital'}, {'zip': '041-8680', 'city': 'Hakodate-shi', 'state': 'Hokkaido', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Tsuyoshi Yamashita', 'role': 'CONTACT', 'email': 'tyamashi@hospital.hakodate.hokkaido.jp', 'phone': '81-138-43-2000'}], 'facility': 'Hospital Hakodate Hokkaido'}, {'zip': '060-0033', 'city': 'Sapporo', 'state': 'Hokkaido', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Tsunemaro Kojo', 'role': 'CONTACT', 'email': 'k.tsunemaro@ja-hokkaidoukouseiren.or.jp', 'phone': '81-11-261-5331'}], 'facility': 'JA Sapporo-Kosei general Hospital', 'geoPoint': {'lat': 43.06667, 'lon': 141.35}}, {'zip': '060-8648', 'city': 'Sapporo', 'state': 'Hokkaido', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hidemichi Watari', 'role': 'CONTACT', 'email': 'watarih@med.hokudai.ac.jp', 'phone': '81-11-716-1161'}], 'facility': 'Hokkaido University Hospita', 'geoPoint': {'lat': 43.06667, 'lon': 141.35}}, {'zip': '673-8558', 'city': 'Akashi-shi', 'state': 'Hyōgo', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Satoshi Yamaguchi', 'role': 'CONTACT', 'email': 's-yama@hp.pref.hyogo.jp', 'phone': '81-78-929-1151'}], 'facility': 'Hyogo Cancer Center'}, {'zip': '660-8511', 'city': 'Amagasaki-shi', 'state': 'Hyōgo', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Kensuke Hori', 'role': 'CONTACT', 'email': 'hori-kensuke@kansaih.johas.go.jp', 'phone': '81-6-6416-1221'}], 'facility': 'Kansai Rosai Hospital'}, {'zip': '670-8540', 'city': 'Himeji-shi', 'state': 'Hyōgo', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Yasushi Mizutani', 'role': 'CONTACT', 'email': 'yappy2727@yahoo.co.jp', 'phone': '81-79-294-2251'}], 'facility': 'Japanese Red Cross Society Himeji Hospital'}, {'zip': '305-8576', 'city': 'Tsukuba', 'state': 'Ibaraki', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Toyomi Sato', 'role': 'CONTACT', 'email': 'toyomi-s@md.tsukuba.ac.jp', 'phone': '81-29-853-3049'}], 'facility': 'University of Tsukuba Hospital', 'geoPoint': {'lat': 36.08333, 'lon': 140.11667}}, {'zip': '020-8505', 'city': 'Morioka', 'state': 'Iwate', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Tsukasa Baba', 'role': 'CONTACT', 'email': 'babatsu@iwate-med.ac.jp', 'phone': '81-19-651-5111'}], 'facility': 'Iwate Medical University Hospital', 'geoPoint': {'lat': 39.7, 'lon': 141.15}}, {'zip': '890-8520', 'city': 'Kagoshima', 'state': 'Kagoshima-ken', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hiroaki Kobayashi', 'role': 'CONTACT', 'email': 'hirokoba@m2.kufm.kagoshima-u.ac.jp', 'phone': '81-99-275-5111'}], 'facility': 'Kagoshima University Medical And Dental Hospital', 'geoPoint': {'lat': 31.56667, 'lon': 130.55}}, {'zip': '890-8760', 'city': 'Kagoshima', 'state': 'Kagoshima-ken', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Toshiaki Nakamura', 'role': 'CONTACT', 'email': 'nakamura-t53@kch.kagoshima.jp', 'phone': '81-99-230-7000'}], 'facility': 'Kagoshima City Hospital', 'geoPoint': {'lat': 31.56667, 'lon': 130.55}}, {'zip': '259-1143', 'city': 'Isehara-shi', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takeshi Hirasawa', 'role': 'CONTACT', 'email': 'hira@is.icc.u-tokai.ac.jp', 'phone': '81-463-93-1121'}], 'facility': 'Tokai University Hospital'}, {'zip': '216-8511', 'city': 'Kawasaki-shi', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Nao Suzuki', 'role': 'CONTACT', 'email': 'nao@marianna-u.ac.jp', 'phone': '81-44-977-8111'}], 'facility': 'St.Marianna University School of Medicine Hospital'}, {'zip': '252-0374', 'city': 'Sagamihara', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Takashi Onda', 'role': 'CONTACT', 'email': 'taonda@med.kitasato-u.ac.jp', 'phone': '81-42-778-8111'}], 'facility': 'Kitasato University Hospital', 'geoPoint': {'lat': 35.56707, 'lon': 139.24167}}, {'zip': '236-0004', 'city': 'Yokohama', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Naho Yokota', 'role': 'CONTACT', 'email': 'nhyokota@yokohama-cu.ac.jp', 'phone': '81-45-787-2800'}], 'facility': 'Yokohama City University Hospital', 'geoPoint': {'lat': 35.43333, 'lon': 139.65}}, {'zip': '236-0037', 'city': 'Yokohama', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Reiko Numazaki', 'role': 'CONTACT', 'email': 'r-numazaki@minamikyousai.jp', 'phone': '81-45-782-2101'}], 'facility': 'Yokohama Minami Kyosai Hospital', 'geoPoint': {'lat': 35.43333, 'lon': 139.65}}, {'zip': '240-8555', 'city': 'Yokohama', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hiroyuki Shigeta', 'role': 'CONTACT', 'email': 'pgkc-0018@jcom.zaq.ne.jp', 'phone': '81-45-331-1961'}], 'facility': "Yokohama Municipal Citizen's Hospital", 'geoPoint': {'lat': 35.43333, 'lon': 139.65}}, {'zip': '241-8515', 'city': 'Yokohama', 'state': 'Kanagawa', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Hisamori Kato', 'role': 'CONTACT', 'email': 'katohh@kcch.jp', 'phone': '81-45-520-2222'}], 'facility': 'Kanagawa Cancer Center', 'geoPoint': {'lat': 35.43333, 'lon': 139.65}}, {'zip': '650-0047', 'city': 'Kobe', 'state': 'Kobe', 'status': 'RECRUITING', 'country': 'Japan', 'contacts': [{'name': 'Shinya Yoshioka', 'role': 'CONTACT', 'email': 's.yoshioka@kcho.jp', 'phone': 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