Ignite Creation Date:
2025-12-25 @ 5:06 AM
Ignite Modification Date:
2025-12-26 @ 4:10 AM
Study NCT ID:
NCT01499927
Status:
COMPLETED
Last Update Posted:
2013-12-19
First Post:
2011-11-15
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}, 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 74766}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2012-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-12', 'completionDateStruct': {'date': '2012-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-12-18', 'studyFirstSubmitDate': '2011-11-15', 'studyFirstSubmitQcDate': '2011-12-22', 'lastUpdatePostDateStruct': {'date': '2013-12-19', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-12-26', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2012-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'duration of intravenous antiinfective therapy until switching', 'timeFrame': '1 year'}], 'secondaryOutcomes': [{'measure': 'costs (per year, per day and patient)', 'timeFrame': '1 year'}, {'measure': 'defined daily doses (per 100 days)', 'timeFrame': '1 year'}, {'measure': 'duration of hospitalization', 'timeFrame': '1 year'}, {'measure': 'ratio of narrow to broad-spectrum antibiotics', 'timeFrame': '1 year'}, {'measure': 'requests for consultations', 'timeFrame': '1 year'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Early reassessment of intravenous antiinfective therapy'], 'conditions': ['Infection as Complication of Medical Care']}, 'referencesModule': {'references': [{'pmid': '26293470', 'type': 'DERIVED', 'citation': 'Beeler PE, Kuster SP, Eschmann E, Weber R, Blaser J. Earlier switching from intravenous to oral antibiotics owing to electronic reminders. Int J Antimicrob Agents. 2015 Oct;46(4):428-33. doi: 10.1016/j.ijantimicag.2015.06.013. Epub 2015 Jul 21.'}]}, 'descriptionModule': {'briefSummary': 'Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs and risk of complications. This study will investigate the impact of displayed reminders in the electronic patient chart after 60h of intravenous therapy with an antiinfective agent.', 'detailedDescription': 'Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs, risk of complications as well as higher workload on nursing. This study will investigate the impact of displayed reminders in the electronic patient chart after 60h of intravenous therapy with an antiinfective agent.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion criteria:\n\n* all in-patients in treatment with an intravenous antiinfective for \\>60h,\n* hospitalized in a ward with computerized physician order entry (cpoe)\n\nExclusion criteria:\n\n* outpatients,\n* ward without cpoe,\n* no intravenous antiinfective treatment'}, 'identificationModule': {'nctId': 'NCT01499927', 'acronym': 'AIR', 'briefTitle': 'Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)', 'organization': {'class': 'OTHER', 'fullName': 'University of Zurich'}, 'officialTitle': 'Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)', 'orgStudyIdInfo': {'id': 'FZMI-KEK-ZH-Nr. 2010-0457'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'electronic reminders', 'description': 'Behavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders', 'interventionNames': ['Other: electronic reminders']}, {'type': 'NO_INTERVENTION', 'label': 'no electronic reminders', 'description': 'Behavioral: Early switching from intravenous to oral antiinfective agents without computerized decision support'}], 'interventions': [{'name': 'electronic reminders', 'type': 'OTHER', 'otherNames': ['computerized decision support'], 'description': 'Behavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders', 'armGroupLabels': ['electronic reminders']}]}, 'contactsLocationsModule': {'locations': [{'zip': '8091', 'city': 'Zurich', 'state': 'Canton of Zurich', 'country': 'Switzerland', 'facility': 'University Hospital Zurich, Center for Clinical Research', 'geoPoint': {'lat': 47.36667, 'lon': 8.55}}], 'overallOfficials': [{'name': 'Juerg Blaser, Professor', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital Zurich, Center for Clinical Research'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Zurich', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}