Ignite Creation Date:
2025-12-25 @ 5:03 AM
Ignite Modification Date:
2026-03-06 @ 2:39 AM
Study NCT ID:
NCT02356718
Status:
COMPLETED
Last Update Posted:
2016-07-27
First Post:
2015-02-02
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Cognitive Training in Inpatient Treatment for Substance Use Disorders
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D019966', 'term': 'Substance-Related Disorders'}], 'ancestors': [{'id': 'D064419', 'term': 'Chemically-Induced Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 111}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2016-07', 'completionDateStruct': {'date': '2016-07', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2016-07-25', 'studyFirstSubmitDate': '2015-02-02', 'studyFirstSubmitQcDate': '2015-02-04', 'lastUpdatePostDateStruct': {'date': '2016-07-27', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2015-02-05', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-07', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Auditory memory capacity - WAIS Digit Span score', 'timeFrame': 'Baseline, 3 weeks', 'description': 'WAIS Digit Span score'}], 'secondaryOutcomes': [{'measure': 'Auditory memory capacity - WAIS Letter-number sequencing score', 'timeFrame': 'Baseline to 3 weeks', 'description': 'WAIS Letter-number sequencing score'}, {'measure': 'Visual memory capacity - WMS Spatial span score', 'timeFrame': 'Baseline to 3 weeks', 'description': 'WMS Spatial span score'}, {'measure': 'Visual memory capacity - WMS Symbol span score', 'timeFrame': 'Baseline to 3 weeks', 'description': 'WMS Symbol span score'}, {'measure': 'Training progress score - Cognitive progress indicator score', 'timeFrame': 'Baseline to 4 weeks', 'description': 'Cognitive progress indicator score'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Substance Use Disorders']}, 'referencesModule': {'references': [{'pmid': '30475014', 'type': 'DERIVED', 'citation': 'Hendershot CS, Wardell JD, Vandervoort J, McPhee MD, Keough MT, Quilty LC. Randomized trial of working memory training as an adjunct to inpatient substance use disorder treatment. Psychol Addict Behav. 2018 Dec;32(8):861-872. doi: 10.1037/adb0000415. Epub 2018 Nov 26.'}], 'seeAlsoLinks': [{'url': 'http://www.camh.ca/en/research', 'label': 'The Centre for Addiction and Mental Health (CAMH) is the leading mental health and addictions research facility in Canada, and one of the largest in the world.'}]}, 'descriptionModule': {'briefSummary': 'This study examines whether computer tasks can improve memory and other cognitive functions among patients receiving inpatient treatment for substance use disorders.', 'detailedDescription': 'Participants will complete cognitive training sessions on a regular basis during inpatient treatment. Alternate versions of the computer tasks will be compared in a randomized design. Primary and secondary outcomes will consist of changes in cognitive performance before and after the training period.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '60 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Participants must be patients registered for inpatient treatment at the Centre for Addiction and Mental Health\n* Age 18-60\n* Fluency in English\n* Able to attend scheduled training sessions\n* Comfortable using a computer and mouse\n\nExclusion Criteria:\n\n* Severe cognitive impairment\n* Current or past psychosis or diagnosis of schizophrenia\n* Photosensitive epilepsy or history of seizures triggered by light\n* Legal mandate to attend treatment'}, 'identificationModule': {'nctId': 'NCT02356718', 'briefTitle': 'Cognitive Training in Inpatient Treatment for Substance Use Disorders', 'organization': {'class': 'OTHER', 'fullName': 'Centre for Addiction and Mental Health'}, 'officialTitle': 'Cognitive Training in Inpatient Treatment for Substance Use Disorders', 'orgStudyIdInfo': {'id': '0422014'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Experimental', 'description': 'Computerized cognitive training activities', 'interventionNames': ['Behavioral: Cognitive training activities', 'Behavioral: Inpatient psychosocial therapy']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Control', 'description': 'Non-adaptive computerized cognitive training activities', 'interventionNames': ['Behavioral: Cognitive training activities', 'Behavioral: Inpatient psychosocial therapy']}], 'interventions': [{'name': 'Cognitive training activities', 'type': 'BEHAVIORAL', 'description': 'Training activities consist of computer tasks designed to improve memory and cognition. The intervention consists of 45-minute training sessions delivered regularly during inpatient treatment.', 'armGroupLabels': ['Control', 'Experimental']}, {'name': 'Inpatient psychosocial therapy', 'type': 'BEHAVIORAL', 'description': 'Group psychosocial therapy delivered in an inpatient setting.', 'armGroupLabels': ['Control', 'Experimental']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Toronto', 'state': 'Ontario', 'country': 'Canada', 'facility': 'Centre for Addiction and Mental Health', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}], 'overallOfficials': [{'name': 'Christian Hendershot, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Centre for Addiction and Mental Health'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Centre for Addiction and Mental Health', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Assistant Professor', 'investigatorFullName': 'Christian Hendershot', 'investigatorAffiliation': 'Centre for Addiction and Mental Health'}}}}