Ignite Creation Date:
2025-12-25 @ 4:27 AM
Ignite Modification Date:
2025-12-26 @ 3:30 AM
Study NCT ID:
NCT01555320
Status:
UNKNOWN
Last Update Posted:
2013-03-20
First Post:
2012-02-29
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Clinical Assessment of Complementary Treatment With Qishen Yiqi Dripping Pills on Ischemic Heart Failure
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'QUADRUPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 640}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2012-03'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-03', 'completionDateStruct': {'date': '2013-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2013-03-19', 'studyFirstSubmitDate': '2012-02-29', 'studyFirstSubmitQcDate': '2012-03-13', 'lastUpdatePostDateStruct': {'date': '2013-03-20', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2012-03-15', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2013-09', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': '6MWT distance', 'timeFrame': '0 month'}, {'measure': '6MWT', 'timeFrame': '3rd month'}, {'measure': '6MWT', 'timeFrame': '6th month'}], 'secondaryOutcomes': [{'measure': 'Composite endpoint', 'timeFrame': '1st,3rd,6th,9th,12th month', 'description': 'all-cause death, frequency of emergency/re-admission to hospital due to HF, frequency of re-admission due to cardiovascular disease, acute coronary syndrome, severe arrhythmia, cardiac shock, revascularization, stroke, pulmonary embolism and peripheral vascular incidences, etc.'}, {'measure': 'Brain natriuretic peptide (BNP)', 'timeFrame': '0,6th month'}, {'measure': 'Echocardiography', 'timeFrame': '0,6th month'}, {'measure': 'Cardiothoracic Ratio(CR)', 'timeFrame': '0,6th month'}, {'measure': 'Cardiac function classification, NYHA', 'timeFrame': '0,1st,3rd,6th,9th,12th month'}, {'measure': 'Minnesota life quality scale', 'timeFrame': '0,1st,3rd,6th,9th,12th month'}, {'measure': 'Scores from the four TCM diagnostic methods', 'timeFrame': '0,1st,3rd,6th,9th,12th month'}, {'measure': 'blood and urine routine tests,liver and renal function tests,serum electrolytes,electrocardiogram (ECG)', 'timeFrame': '0,3rd,6thmonth'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'conditions': ['Ischemic Heart Failure']}, 'referencesModule': {'references': [{'pmid': '41268060', 'type': 'DERIVED', 'citation': 'Zhou Z, Wang S, Du Y, Zhao Z, Bi Y, Su Q, Hou Y, Wang X, Mao J. Effect of Qishen Yiqi Dripping Pill on Clinical Outcomes in Patients with Ischemic Heart Failure: A Post-Hoc Analysis of the CACT-IHF Randomized Trial. Drug Des Devel Ther. 2025 Nov 15;19:10163-10174. doi: 10.2147/DDDT.S556373. eCollection 2025.'}, {'pmid': '23672353', 'type': 'DERIVED', 'citation': 'Hou YZ, Wang S, Zhao ZQ, Wang XL, Li B, Soh SB, Mao JY. Clinical assessment of complementary treatment with Qishen Yiqi dripping pills on ischemic heart failure: study protocol for a randomized, double-blind, multicenter, placebo-controlled trial (CACT-IHF). Trials. 2013 May 14;14:138. doi: 10.1186/1745-6215-14-138.'}]}, 'descriptionModule': {'briefSummary': 'CACT-IHF aims to evaluate the clinical efficacy and safety of Qishen Yiqi Dripping Pills in treating ischemic heart failure. Meeting the diagnosis, inclusion and exclusion criteria, the study plans to recruit 640 cases from 35 upper class hospitals in China, who are divided into two groups (treatment and control group) by central randomization service. The treatment group will be administrated with one bag of Qishen Yiqi Dripping Pills (0.52g/bag) three times a day in addition to standardized western medications. Whereas the control group will be given one bag of Qishen Yiqi Dripping Pills dummy (0.52g/bag) three times a day in addition to standardized western medications. Efficacy indicators include primary indicator (6 minute walk test) and secondary indicators: composite endpoint consisting of all-cause death, emergency/re-admission to hospital due to HF, frequency of re-admission due to cardiovascular disease, acute coronary syndrome, severe arrhythmia, cardiac shock, revascularization, stroke, pulmonary embolism and peripheral vascular incidences, etc.; Brain Natriuretic Peptide; echocardiography; cardiothoracic ratio; NYHA cardiac function classification; Minnesota life quality scale; scores from the four traditional chinese medicine (TCM) diagnostic methods). Other indicators include blood cholesterol, triglyceride, high density cholesterol and low density cholesterol. Safety indicators include blood pressure, heart rate, blood and urine routine tests, liver and renal function tests, serum electrolytes, electrocardiogram and adverse events. All of the patients will receive interventional drug treatment for 6 months. Follow up is needed on the 1st, 3rd, 6th, 9th, 12th month after recruitment. All patients will be followed up until the end of study (Refers to the 12th month of the last case recruited into the study).'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '79 Years', 'minimumAge': '40 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age 40 to 79\n* Patients with ischemic heart failure：\n\n * LVEF less than or equal to 45% measured by echocardiography in modified Simpson method\n * History of prior myocardial infarction with or without percutaneous coronary intervention (PCI) or/and coronary artery bypass grafting (CABG);\n * Coronary angiography (CAG) or coronary CTA shows more than or equal to 50% stenosis in at least one of the main coronary arteries with or without revascularization, of which the researcher thinks that it is closely related to heart failure;\n * With or without dyspnea, fatigue and fluid retention (edema) etc.\n* History of heart failure or present with heart failure symptoms for at least 3 months;\n* New York Heart Association (NYHA) Class II to IV;\n* Submitted informed consent\n\nExclusion Criteria:\n\n* Acute heart failure or acute exacerbation of chronic heart failure\n* Those who have one of the following diseases:\n\n * Acute coronary syndrome within 30 days\n * Revascularization therapy within 6 months\n * Uncontrolled hypertension with systolic pressure more than or equal to 180mmHg and/or diastolic pressure more than or equal to 110mmHg\n * Second degree type 2 or worse sinoatrial/atrioventricular block without implantation of pacemaker or uncontrolled malignant cardiac arrhythmia\n * Dilated cardiomyopathy\n * Hypertrophic obstructive cardiomyopathy\n * Myocarditis\n * Pulmonary artery embolism\n * Severe valvular heart disease\n * Pulmonary heart disease\n * Stroke within 6 months\n* Cardiac resynchronization therapy\n* Applied diuretics, cardiotonic agents or vasodilators intravenously within 7 days\n* Severe endocrine diseases such as hyperthyroidism, etc.\n* History of malignant tumor\n* Hemoglobin (HB )≤ 9g/dl\n* Alanine aminotransferase (ALT) \\> 2 times the upper limit of normal\n* Serum creatinine \\> 265 μmol/L\n* Mental disorder\n* Being pregnant, planning for pregnancy or breastfeeding\n* Suspicious or definite allergy to intervention drugs\n* Participated in other trials within 2 months\n* Unable to walk autonomously due to physical disabilities'}, 'identificationModule': {'nctId': 'NCT01555320', 'acronym': 'CACT-IHF', 'briefTitle': 'Clinical Assessment of Complementary Treatment With Qishen Yiqi Dripping Pills on Ischemic Heart Failure', 'organization': {'class': 'OTHER_GOV', 'fullName': "State Administration of Traditional Chinese Medicine of the People's Republic of China"}, 'officialTitle': 'Clinical Assessment of Complementary Treatment With Qishen Yiqi Dripping Pills on Ischemic Heart Failure (CACT-IHF) A Randomized, Double-blind, Multicenter, Placebo-controlled Trial', 'orgStudyIdInfo': {'id': '201007001-02'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'PLACEBO_COMPARATOR', 'label': 'Qishen Yiqi dripping pills dummy', 'interventionNames': ['Drug: Qishen Yiqi dripping pills dummy']}, {'type': 'EXPERIMENTAL', 'label': 'Qishen Yiqi Dripping Pills', 'interventionNames': ['Drug: Qishen Yiqi Dripping Pills']}], 'interventions': [{'name': 'Qishen Yiqi Dripping Pills', 'type': 'DRUG', 'description': 'One packet of Qishen Yiqi Dripping Pills (0.52g) will be given three times a day in addition to regular western medications for the first 6 months, and regular western medications only for the subsequent 6 months.', 'armGroupLabels': ['Qishen Yiqi Dripping Pills']}, {'name': 'Qishen Yiqi dripping pills dummy', 'type': 'DRUG', 'description': 'One packet of Qishen Yiqi Dripping Pills dummy (0.52g) will be given three times a day in addition to regular western medications for the first 6 months, and regular western medications only for the subsequent 6 months.', 'armGroupLabels': ['Qishen Yiqi dripping pills dummy']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Beijing', 'state': 'Beijing Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yao Han, Dr.', 'role': 'CONTACT', 'email': 'Hanyao1212@126.com'}, {'name': 'Hongxu Liu, Prof', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Beijing Hospital of Traditional Chinese Medicine', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'city': 'Beijing', 'state': 'Beijing Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Bingqi Wei, Dr.', 'role': 'CONTACT', 'email': 'weibing918q@sina.com'}, {'name': 'Jian Zhang, Prof', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Fuwai Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'city': 'Beijing', 'state': 'Beijing Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yang Miao, Dr.', 'role': 'CONTACT', 'email': 'Miya9@163.com'}, {'name': 'Yang Miao, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Xiyuan Hospital of China Academy of Chinese Medical Sciences', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'city': 'Guangdong', 'state': 'Guangdong', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Xiaogang Sheng, Dr.', 'role': 'CONTACT', 'email': 'shengxiaogang1@sina.com.cn'}, {'name': 'Huanlin Wu, Prof', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Guangdong Provincial Hospital of TCM'}, {'city': 'Guiyang', 'state': 'Guizhou', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Tingchun Wu, Dr.', 'role': 'CONTACT', 'email': '649164263@qq.com'}, {'name': 'Tao Xu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Second Affiliated Hospital of TCM College Guiyang', 'geoPoint': {'lat': 26.58333, 'lon': 106.71667}}, {'city': 'Baoding', 'state': 'Hebei', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Xuebin Cao, Dr.', 'role': 'CONTACT', 'email': 'cxb13633227588@126.com'}, {'name': 'Xuebin Cao, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "252 Hospital of Chinese People's Liberation Army", 'geoPoint': {'lat': 38.87288, 'lon': 115.46246}}, {'city': 'Heilongjiang', 'state': 'Heilongjiang', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yan Wang, Dr.', 'role': 'CONTACT', 'email': '19911737@qq.com'}, {'name': 'Yang Li, Dr.', 'role': 'CONTACT', 'email': '19911737@qq.com'}, {'name': 'Yabin Zhou, Prof', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The 1st Affiliated Hospital of Heilongjiang Traditional Chinese Medicine University'}, {'city': 'Zhengzhou', 'state': 'Henan', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Tinghai Du, Dr.', 'role': 'CONTACT', 'email': 'dth2010@163.com'}, {'name': 'Mingjun Zhu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The First Affiliated Hospital of Henan University of TCM', 'geoPoint': {'lat': 34.75778, 'lon': 113.64861}}, {'city': 'Hengyang', 'state': 'Hunan', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Huan Liu, Dr.', 'role': 'CONTACT'}, {'name': 'Xiaofeng Ma, Dr.', 'role': 'SUB_INVESTIGATOR'}], 'facility': 'The Affiliated Nanhua Hospital of Nanhua University', 'geoPoint': {'lat': 26.88946, 'lon': 112.61888}}, {'city': 'Nanjing', 'state': 'Jiangsu', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Bo Zhu, Dr.', 'role': 'CONTACT', 'email': 'najahannah@sina.com'}, {'name': 'Xiaohu Chen, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Jiangsu Province Traditional Chinese Medicine Hospital', 'geoPoint': {'lat': 32.06167, 'lon': 118.77778}}, {'city': 'Nanjing', 'state': 'Jiangsu', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Zhongxing Shao, Dr.', 'role': 'CONTACT', 'email': 'Szx790102@sohu.com'}, {'name': 'Ning Gu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Nanjing Hospital of T.C.M', 'geoPoint': {'lat': 32.06167, 'lon': 118.77778}}, {'city': 'Nanchang', 'state': 'Jiangxi', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Peng Deng, Dr.', 'role': 'CONTACT', 'email': 'dengpeng615@sina.com'}, {'name': 'Zhongyong Liu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Affiliated Hospital of Jiangxi University of TCM', 'geoPoint': {'lat': 28.68396, 'lon': 115.85306}}, {'city': 'Changchun', 'state': 'Jilin', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yudan Tian, Dr.', 'role': 'CONTACT', 'email': '30880356@qq.com'}, {'name': 'Yue Deng, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Affiliated Hospital To Changchun University of Chinese Medicine', 'geoPoint': {'lat': 43.88, 'lon': 125.32278}}, {'city': 'Changchun', 'state': 'Jilin', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yaqiu Jiang, Dr.', 'role': 'CONTACT', 'email': 'yaqiujiang@163.com'}, {'name': 'Yaqiu Jiang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The First Hospital of Jilin University', 'geoPoint': {'lat': 43.88, 'lon': 125.32278}}, {'city': 'Shenyang', 'state': 'Liaoning', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Ying Yang, Dr.', 'role': 'CONTACT', 'email': 'Yang_ying_2002@sina.com'}, {'name': 'Fengrong Wang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Affiliated Hospital of Liaoning University of Traditional Chinese Medicine', 'geoPoint': {'lat': 41.79222, 'lon': 123.43278}}, {'city': 'Shenyang', 'state': 'Liaoning', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Tao Ding, Dr.', 'role': 'CONTACT', 'email': 'chensn@sj-hospital.org'}, {'name': 'Suning Chen, Prof', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Shengjing Hospital of China Medical University', 'geoPoint': {'lat': 41.79222, 'lon': 123.43278}}, {'city': 'Shenyang', 'state': 'Liaoning', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Haiyan Shan, Dr.', 'role': 'CONTACT', 'email': 'shanhy024@163.com'}, {'name': 'Xiaojuan Bai, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The First Hospital of China Medical University', 'geoPoint': {'lat': 41.79222, 'lon': 123.43278}}, {'city': 'Shenyang', 'state': 'Liaoning', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Donghai Wang, Dr.', 'role': 'CONTACT', 'email': 'fine_dongbo@163.com'}, {'name': 'Bo Dong, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine', 'geoPoint': {'lat': 41.79222, 'lon': 123.43278}}, {'city': 'Xianyang', 'state': 'Shaanxi', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Jing Qi', 'role': 'CONTACT', 'email': '404317104@qq.com'}, {'name': 'Yonggang Wang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Second Affiliated Hospital of Shaanxi University of Chinese Medicine', 'geoPoint': {'lat': 34.33778, 'lon': 108.70261}}, {'city': 'Shandong', 'state': 'Shandong', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yunlun Li, Dr.', 'role': 'CONTACT', 'email': 'liyunlun@163.com'}, {'name': 'Yitao Xue', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Shandong Province Traditional Chinese Medicine University Affiliated Hospital'}, {'city': 'Shanghai', 'state': 'Shanghai Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Qingfen Zhou, Dr.', 'role': 'CONTACT', 'email': 'zhouqingfen@hotmail.com'}, {'name': 'Fengru Zhang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Ruijin Hospital Affiliated to The Shanghai Jiao Tong University Medical School', 'geoPoint': {'lat': 31.22222, 'lon': 121.45806}}, {'city': 'Shanghai', 'state': 'Shanghai Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yongming Liu, Dr.', 'role': 'CONTACT', 'email': 'liuyongming@foxmail.com'}, {'name': 'Xiaolong Wang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Shanghai Shuguang Hospital', 'geoPoint': {'lat': 31.22222, 'lon': 121.45806}}, {'city': 'Taiyuan', 'state': 'Shanxi', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Tianfu Niu, Dr.', 'role': 'CONTACT', 'email': 'niutianfu2584@sina.com'}, {'name': 'Tianfu Niu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Traditional Chinese Medicine Hospital of Shan Xi Province', 'geoPoint': {'lat': 37.86944, 'lon': 112.56028}}, {'city': 'Chengdu', 'state': 'Sichuan', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Li Jiang, Dr.', 'role': 'CONTACT', 'email': 'cdwwx729@163.com'}, {'name': 'Weixing Wang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Teaching Hospital of Chengdu University of TCM', 'geoPoint': {'lat': 30.66667, 'lon': 104.06667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Jun Tian, Dr.', 'role': 'CONTACT', 'email': 'Tianjun6666@hotmail.com'}, {'name': 'Tiemin Jiang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "Affiliated Hospital of Medical College of Chinese People's Armed Police Forces", 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yazhu Hou', 'role': 'CONTACT', 'email': 'mreleven@163.com'}, {'name': 'Jingyuan Mao, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'First Teaching Hospital of Tianjin University of Traditional Chinese Medicine', 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Tao Wang, Dr.', 'role': 'CONTACT', 'email': 'Wangtao973@163.com'}, {'name': 'Yingqiang Zhao, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Second Affiliated Hospital of Tianjin University of TCM', 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Ruyu Yuan, Dr.', 'role': 'CONTACT', 'email': 'tjcardio@gmail.com'}, {'name': 'Ruyu Yuan, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The 2nd Hospital of Tianjin Medical University', 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Jie Geng, Dr.', 'role': 'CONTACT', 'email': 'gengjie_1973@126.com'}, {'name': 'Shutao Chen, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Tian Jin Chest Hospital', 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Tianjin', 'state': 'Tianjin Municipality', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Chuanhui Huang, Dr.', 'role': 'CONTACT', 'email': 'huangchuanhui66@sina.com'}, {'name': 'Ruihong Fan, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Tianjin Academy of Traditional Chinese Medicine Affliated Hospital', 'geoPoint': {'lat': 39.14222, 'lon': 117.17667}}, {'city': 'Ürümqi', 'state': 'Xinjiang', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Dongqing An, Dr.', 'role': 'CONTACT', 'email': 'wxf87112008@163.com'}, {'name': 'Xiaofeng Wang, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Traditional Chinese Medical Hospital of Xinjiang Uyghur Autonomous Region', 'geoPoint': {'lat': 43.80096, 'lon': 87.60046}}, {'city': 'Anhui', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Zhengbin Shao, Dr.', 'role': 'CONTACT', 'email': 'shaozhengbin@126.com'}, {'name': 'Xiaohua Dai, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The First Affiliated Hospital of Anhui University of TCM'}, {'city': 'Beijing', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Jinjin Lu, Dr.', 'role': 'CONTACT', 'email': 'Lu2008jinjin@126.com'}, {'name': 'Yang Wu, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Dong Fang Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}], 'centralContacts': [{'name': 'Yazhu Hou, Dr.', 'role': 'CONTACT', 'email': 'mreleven@163.com', 'phone': '8622-27432325'}], 'overallOfficials': [{'name': 'Jingyuan Mao, Dr.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'First Teaching Hospital of Tianjin University of Traditional Chinese Medicine'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': "State Administration of Traditional Chinese Medicine of the People's Republic of China", 'class': 'OTHER_GOV'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Prof.', 'investigatorFullName': 'Jingyuan Mao', 'investigatorAffiliation': 'First Teaching Hospital of Tianjin University of Traditional Chinese Medicine'}}}}