Ignite Creation Date:
2025-12-25 @ 4:24 AM
Ignite Modification Date:
2025-12-26 @ 3:27 AM
Study NCT ID:
NCT05507320
Status:
UNKNOWN
Last Update Posted:
2022-08-18
First Post:
2022-08-09
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Neural Circuits for Action Perception
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D004827', 'term': 'Epilepsy'}], 'ancestors': [{'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'OTHER'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 30}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2021-09-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2022-08', 'completionDateStruct': {'date': '2025-09-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2022-08-17', 'studyFirstSubmitDate': '2022-08-09', 'studyFirstSubmitQcDate': '2022-08-17', 'lastUpdatePostDateStruct': {'date': '2022-08-18', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2022-08-18', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-09-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Selectivity for kinematics and movement type in neurophysiological responses', 'timeFrame': 'Through study completion, an average of 2 years.', 'description': 'Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution.\n\nWe will assess selectivity for kinematics for each movement type'}, {'measure': 'Evoked responses by action execution', 'timeFrame': 'Through study completion, an average of 2 years.', 'description': 'Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution.\n\nWe will quantify responses evoked by action execution'}, {'measure': 'Evoked responses by action observation', 'timeFrame': 'Through study completion, an average of 2 years.', 'description': 'Measure intracranial field potentials (in microvolts) in the gamma frequency band through neurophysiological responses comparing neural responses during action perception versus execution.\n\nWe will quantify responses evoked by action observation'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Epilepsy']}, 'descriptionModule': {'briefSummary': 'Study the mechanisms underlying action recognition and execution', 'detailedDescription': 'Subjects will participate in a task where they have to either\n\n1. Perform a movement\n2. Observe an actor performing a movement There are three types of actions including different kinematics and grip types The goal is to compare the neural circuits activated by action execution versus action observation.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'maximumAge': '70 Years', 'minimumAge': '14 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Patients with pharmacologically intractable epilepsy undergoing invasive implantation of electrodes', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Patients with pharmacologically intractable epilepsy\n\nExclusion Criteria:\n\n* Any situation that may put the patient at risk'}, 'identificationModule': {'nctId': 'NCT05507320', 'briefTitle': 'Neural Circuits for Action Perception', 'organization': {'class': 'OTHER', 'fullName': "Boston Children's Hospital"}, 'officialTitle': 'Neural Circuits for Action Perception', 'orgStudyIdInfo': {'id': 'IRB_P0405065R'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Mechanisms of action perception and execution', 'type': 'BEHAVIORAL', 'description': 'Study the mechanisms of action perception and execution'}]}, 'contactsLocationsModule': {'locations': [{'zip': '02115', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Dominguez Robleinscky', 'role': 'CONTACT', 'email': 'domingues.robleinscky@childrens.harvard.edu', 'phone': '617-919-2530'}, {'name': 'Gabriel Kreiman', 'role': 'CONTACT', 'email': 'gabriel.kreiman@tch.harvard.edu', 'phone': '6179192242'}], 'facility': "Boston Children's Hospital", 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}], 'centralContacts': [{'name': 'Gabriel Kreiman, PhD', 'role': 'CONTACT', 'email': 'gabriel.kreiman@tch.harvard.edu', 'phone': '6179192530'}], 'overallOfficials': [{'name': 'Gabriel Kreiman, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'CHB'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': "Boston Children's Hospital", 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Gabriel Kreiman', 'investigatorAffiliation': "Boston Children's Hospital"}}}}