Ignite Creation Date:
2025-12-25 @ 4:20 AM
Ignite Modification Date:
2025-12-26 @ 3:21 AM
Study NCT ID:
NCT00364520
Status:
COMPLETED
Last Update Posted:
2015-05-21
First Post:
2006-08-14
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Molecular Epidemiology of Benzene-exposed Workers.
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D006402', 'term': 'Hematologic Diseases'}], 'ancestors': [{'id': 'D006425', 'term': 'Hemic and Lymphatic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'ECOLOGIC_OR_COMMUNITY'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 2000}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2003-08'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-05', 'completionDateStruct': {'date': '2009-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2015-05-19', 'studyFirstSubmitDate': '2006-08-14', 'studyFirstSubmitQcDate': '2006-08-14', 'lastUpdatePostDateStruct': {'date': '2015-05-21', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2006-08-15', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2009-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.', 'timeFrame': 'August 2003 - December 2009', 'description': 'Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers'}], 'secondaryOutcomes': [{'measure': 'Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.', 'timeFrame': 'August 2003 - December 2009', 'description': 'Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Hematologic Diseases', 'Benzene', 'Genetic Polymorphisms'], 'conditions': ['Hematologic Diseases']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.', 'detailedDescription': 'The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '67 Years', 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Shanghai Workers', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\nWorked for at least one year in a monitored environment Have at least one physical examination recorded\n\n\\-\n\nExclusion Criteria:\n\nHistory of cancer, radiation exposure, chemotherapy\n\n\\-'}, 'identificationModule': {'nctId': 'NCT00364520', 'briefTitle': 'Molecular Epidemiology of Benzene-exposed Workers.', 'organization': {'class': 'OTHER', 'fullName': 'University of Colorado, Denver'}, 'officialTitle': 'Molecular Epidemiology of Benzene-exposed Workers in Shanghai,China', 'orgStudyIdInfo': {'id': '02-0037'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Shanghai Workers', 'description': 'Shanghai Workers', 'interventionNames': ['Other: Shanghai workers']}], 'interventions': [{'name': 'Shanghai workers', 'type': 'OTHER', 'armGroupLabels': ['Shanghai Workers']}]}, 'contactsLocationsModule': {'locations': [{'zip': '200032', 'city': 'Shanghai', 'country': 'China', 'facility': 'Joint Sino-US Clinical and Molecular Laboratory (JCML)', 'geoPoint': {'lat': 31.22222, 'lon': 121.45806}}], 'overallOfficials': [{'name': 'Richard D Irons, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Colorado at Denver and Health Sciences Ctr'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Colorado, Denver', 'class': 'OTHER'}, 'collaborators': [{'name': 'Fudan University', 'class': 'OTHER'}, {'name': 'University of Cincinnati', 'class': 'OTHER'}, {'name': 'ExxonMobil Biomedical Sciences, Inc.', 'class': 'INDUSTRY'}, {'name': 'British Petroleum P.L.C.', 'class': 'INDUSTRY'}, {'name': 'Chevron Corporation', 'class': 'INDUSTRY'}, {'name': 'ConocoPhillips', 'class': 'INDUSTRY'}, {'name': 'Exxon Mobil', 'class': 'INDUSTRY'}, {'name': 'Marathon Ashland', 'class': 'UNKNOWN'}, {'name': 'Shell Chemicals', 'class': 'INDUSTRY'}], 'responsibleParty': {'type': 'SPONSOR'}}}}