Ignite Creation Date:
2025-12-25 @ 4:17 AM
Ignite Modification Date:
2026-03-02 @ 4:00 PM
Study NCT ID:
NCT03312920
Status:
WITHDRAWN
Last Update Posted:
2025-01-10
First Post:
2017-10-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Investigating Memory Retrieval Improvement in Healthy Subjects
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 0}}, 'statusModule': {'whyStopped': 'Planned changed based on the outcome of another study', 'overallStatus': 'WITHDRAWN', 'startDateStruct': {'date': '2017-09-27', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-01', 'completionDateStruct': {'date': '2024-09-05', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2025-01-08', 'studyFirstSubmitDate': '2017-10-12', 'studyFirstSubmitQcDate': '2017-10-12', 'lastUpdatePostDateStruct': {'date': '2025-01-10', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-10-18', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2023-10-06', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Associative Memory assessed by a Face Name Associate Memory experiment', 'timeFrame': 'Associate Memory is assessed after a 10 minutes break following the study phase', 'description': 'Changes in performance in the Face Name Associate memory task is compared between the 2 groups (1. Real tDCS+ Face Name Associate memory task \\& 2. Sham tDCS+ Face Name Associate memory task) to investigate the influence of tDCS on Associative Memory.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': True}, 'conditionsModule': {'keywords': ['tDCS, accelerated learning, memory'], 'conditions': ['Healthy Adults']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.', 'detailedDescription': 'Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.\n\nTranscranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether learning can be accelerated and associative memory improved by using tDCS, this study will compare the performance in a Face Name Associate memory task from 3 groups. The first group will get active aodal tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task and the third group will get active cathodal tDCS.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '35 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age: 18-35 years Native English Speaker\n\nExclusion Criteria:\n\n* History of severe head injuries, epileptic insults, or heart disease. Severe psychiatric disorders and severe untreated medical problems. Contraindications for tDCS (pregnant women, implanted devices)'}, 'identificationModule': {'nctId': 'NCT03312920', 'briefTitle': 'Investigating Memory Retrieval Improvement in Healthy Subjects', 'organization': {'class': 'OTHER', 'fullName': 'The University of Texas at Dallas'}, 'officialTitle': 'Investigating Memory Retrieval Improvement in Healthy Subjects', 'orgStudyIdInfo': {'id': '17-132'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'active anodal tDCS', 'description': 'active anodal tDCS with Face Name associate Memory task', 'interventionNames': ['Device: active anodal tDCS']}, {'type': 'SHAM_COMPARATOR', 'label': 'Sham tDCS', 'description': 'sham tDCS with Face Name associate Memory task', 'interventionNames': ['Device: sham tDCS']}, {'type': 'EXPERIMENTAL', 'label': 'active cathodal tDCS', 'description': 'active cathodal tDCS with Face Name associate Memory task', 'interventionNames': ['Device: active cathodal tDCS']}], 'interventions': [{'name': 'active anodal tDCS', 'type': 'DEVICE', 'description': 'active anodal tDCS with memory task', 'armGroupLabels': ['active anodal tDCS']}, {'name': 'sham tDCS', 'type': 'DEVICE', 'description': 'sham tDCS with memory task', 'armGroupLabels': ['Sham tDCS']}, {'name': 'active cathodal tDCS', 'type': 'DEVICE', 'description': 'active cathodal tDCS with memory task', 'armGroupLabels': ['active cathodal tDCS']}]}, 'contactsLocationsModule': {'locations': [{'zip': '75080', 'city': 'Richardson', 'state': 'Texas', 'country': 'United States', 'facility': 'University of Texas at Dallas', 'geoPoint': {'lat': 32.94818, 'lon': -96.72972}}], 'overallOfficials': [{'name': 'Sven Vanneste, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'The University of Texas at Dallas'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'The University of Texas at Dallas', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate professor', 'investigatorFullName': 'Sven Vanneste', 'investigatorAffiliation': 'The University of Texas at Dallas'}}}}