Ignite Creation Date:
2025-12-25 @ 4:13 AM
Ignite Modification Date:
2026-02-25 @ 8:48 PM
Study NCT ID:
NCT02894320
Status:
COMPLETED
Last Update Posted:
2018-08-31
First Post:
2016-09-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Dynamic ASPECTS of Internal PRE-ACTIVATION of Effects Sensors of Voluntary ACTION in PARKINSON's Disease
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D010300', 'term': 'Parkinson Disease'}], 'ancestors': [{'id': 'D020734', 'term': 'Parkinsonian Disorders'}, {'id': 'D001480', 'term': 'Basal Ganglia Diseases'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D009069', 'term': 'Movement Disorders'}, {'id': 'D000080874', 'term': 'Synucleinopathies'}, {'id': 'D019636', 'term': 'Neurodegenerative Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D000067289', 'term': 'Behavior Observation Techniques'}], 'ancestors': [{'id': 'D011580', 'term': 'Psychological Techniques'}, {'id': 'D008919', 'term': 'Investigative Techniques'}, {'id': 'D004191', 'term': 'Behavioral Disciplines and Activities'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'OTHER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 28}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-03', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-08', 'completionDateStruct': {'date': '2017-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2018-08-30', 'studyFirstSubmitDate': '2016-09-05', 'studyFirstSubmitQcDate': '2016-09-05', 'lastUpdatePostDateStruct': {'date': '2018-08-31', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2016-09-09', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-06', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Reaction time', 'timeFrame': 'baseline', 'description': 'time measured in seconds'}, {'measure': 'error rate', 'timeFrame': 'baseline'}]}, 'conditionsModule': {'keywords': ["Parkinson's disease", 'Voluntary action', 'Action-effect preactivation', 'Action-effect prediction'], 'conditions': ["Parkinson's Disease"]}, 'descriptionModule': {'briefSummary': 'The ability to predict sensory effects of people\'s own motor actions is a key component of Human action realization. Recent studies revealed this anticipation process to be involved in early and late stages of voluntary actions. Nevertheless, the question whether the action-effect anticipation is impacted or not by "motor pathologies", such as the Parkinson\'s disease, remains unclear. The current study is aimed to clarify this issue by using a subliminal priming paradigm in patients with Parkinson\'s disease and in matched control participants. Indeed, subliminal primes corresponding to visual action-effects are displayed at different time points before the actions\' execution. Results should allow to determine whether or not the action-effect prediction is impaired at different stages of voluntary action in patients with Parkinson\'s disease.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': "patients with Parkinson's disease, according to the MDS-UPDRS III (Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale), matched for gender and for age with healthy subjects from a database.\n\nThis database has already been constituted by the CNRS (Centre national de la recherche scientifique, Laboratory of Psychology of Perception - UMR8242).", 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Adults age 18 years and older\n* Parkinson's disease\n\nExclusion Criteria:\n\n* Other pathology or neurological or psychiatric history\n* Known pregnancy or breastfeeding\n* Absence of affiliation to social security or universal health coverage (CMU)\n* Person under legal protection\n* Patient's opposition to participate"}, 'identificationModule': {'nctId': 'NCT02894320', 'acronym': 'DYNIDEO', 'briefTitle': "Dynamic ASPECTS of Internal PRE-ACTIVATION of Effects Sensors of Voluntary ACTION in PARKINSON's Disease", 'organization': {'class': 'NETWORK', 'fullName': 'Fondation Ophtalmologique Adolphe de Rothschild'}, 'officialTitle': "The Impact of Parkinson's Disease on Internal Preactivation of Sensory Effects of Intention-based Actions. A Subliminal Priming Study", 'orgStudyIdInfo': {'id': 'JBL_2014-28'}}, 'armsInterventionsModule': {'armGroups': [{'label': "Parkinson's disease", 'interventionNames': ['Behavioral: Behavioral observation']}, {'label': 'Healthy subjects', 'description': "gender and age matched with Parkinson's disease patients, whose data will be extracted from an existing database", 'interventionNames': ['Behavioral: Behavioral observation']}], 'interventions': [{'name': 'Behavioral observation', 'type': 'BEHAVIORAL', 'armGroupLabels': ['Healthy subjects', "Parkinson's disease"]}]}, 'contactsLocationsModule': {'locations': [{'zip': '75019', 'city': 'Paris', 'country': 'France', 'facility': 'Fondation Ophtalmologique Adolphe de Rothschild', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Fondation Ophtalmologique Adolphe de Rothschild', 'class': 'NETWORK'}, 'responsibleParty': {'type': 'SPONSOR'}}}}