Ignite Creation Date:
2025-12-25 @ 4:07 AM
Ignite Modification Date:
2026-03-22 @ 5:50 AM
Study NCT ID:
NCT00494520
Status:
COMPLETED
Last Update Posted:
2017-09-19
First Post:
2007-06-28
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Cognitive Therapy to Improve Word Finding
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000849', 'term': 'Anomia'}, {'id': 'D001037', 'term': 'Aphasia'}, {'id': 'D000070642', 'term': 'Brain Injuries, Traumatic'}, {'id': 'D020521', 'term': 'Stroke'}], 'ancestors': [{'id': 'D007806', 'term': 'Language Disorders'}, {'id': 'D003147', 'term': 'Communication Disorders'}, {'id': 'D019954', 'term': 'Neurobehavioral Manifestations'}, {'id': 'D009461', 'term': 'Neurologic Manifestations'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D013064', 'term': 'Speech Disorders'}, {'id': 'D001930', 'term': 'Brain Injuries'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D006259', 'term': 'Craniocerebral Trauma'}, {'id': 'D020196', 'term': 'Trauma, Nervous System'}, {'id': 'D014947', 'term': 'Wounds and Injuries'}, {'id': 'D002561', 'term': 'Cerebrovascular Disorders'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 78}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-07'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2014-04', 'completionDateStruct': {'date': '2009-06', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2017-09-15', 'studyFirstSubmitDate': '2007-06-28', 'studyFirstSubmitQcDate': '2007-06-28', 'lastUpdatePostDateStruct': {'date': '2017-09-19', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2007-06-29', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2009-06', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Improved picture naming of trained words.', 'timeFrame': 'Following conclusion of word treatment.', 'description': 'Overall accuracy of named trained items'}], 'secondaryOutcomes': [{'measure': 'Improved picture naming of trained words.', 'timeFrame': 'At 6 months after conclusion of word treatment', 'description': 'Overall accuracy of named trained items'}, {'measure': 'Improved picture naming of untrained words.', 'timeFrame': 'Following conclusion of word treatment.', 'description': 'Overall accuracy of named untrained items'}, {'measure': 'Improved picture naming of untrained words.', 'timeFrame': 'At 6 months after conclusion of word treatment', 'description': 'Overall accuracy of named untrained items'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Anomia', 'Aphasia', 'Traumatic Brain Injury', 'Cerebrovascular Accident'], 'conditions': ['Anomia', 'Aphasia', 'Traumatic Brain Injury', 'Cerebrovascular Accident']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'http://www9.georgetown.edu/faculty/friedmar/index.html', 'label': 'Cognitive Neuropsychology Lab at Georgetown University Medical Center'}]}, 'descriptionModule': {'briefSummary': 'Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these individuals.', 'detailedDescription': 'Difficulty finding words is common in patients with aphasia subsequent to left hemisphere stroke. This study will compare two cognitive therapies for the treatment of acquired word finding difficulties. The therapies use different types of cues. All participants will receive both therapies. Participants in this study will undergo a comprehensive and detailed assessment of language and other cognitive skills. The two treatments will be compared for their efficacy.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Word finding difficulty subsequent to stroke, traumatic brain injury, brain surgery or other brain damage occuring at least 6 month prior to participation\n* Ability to attend 2 sessions per week for several months at Georgetown University in Washington, DC\n\nExclusion Criteria:\n\n* History of learning disabilities\n* Best corrected vision less than 20/40\n* Corrected hearing within functional limits\n* Less than 10 years formal education\n* Significant memory or comprehension problems'}, 'identificationModule': {'nctId': 'NCT00494520', 'briefTitle': 'Cognitive Therapy to Improve Word Finding', 'organization': {'class': 'OTHER', 'fullName': 'Georgetown University'}, 'officialTitle': 'Learning Paradigms in Aphasia Rehabilitation', 'orgStudyIdInfo': {'id': 'R01DC006934-01', 'link': 'https://reporter.nih.gov/quickSearch/R01DC006934-01', 'type': 'NIH'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Errorful training condition', 'description': 'A type of anomia rehabilitation paradigm which allows for errors. The intervention involves providing minimal auditory cues to allow for errors in picture naming.', 'interventionNames': ['Procedure: Errorful training condition']}, {'type': 'EXPERIMENTAL', 'label': 'Errorless training condition', 'description': 'A type of anomia rehabilitation paradigm in which the situation surrounding the performance of the desired task (i.e., picture naming) is controlled to prevent errors. The intervention involves providing maximal auditory cues to prevent errors in picture naming.', 'interventionNames': ['Procedure: Errorless training condition']}], 'interventions': [{'name': 'Errorful training condition', 'type': 'PROCEDURE', 'description': 'Errorful training condition: Participant saw a picture and named it without any cues. If an error was produced, the cue with the least amount of information was provided (e.g. for "pumpkin", "pu"). Cues with increasing information were provided until the picture was correctly named (e.g. for "pumpkin": "pump", "pumpki", then "pumpkin"). Once the correct name was provided, the trial ended.', 'armGroupLabels': ['Errorful training condition']}, {'name': 'Errorless training condition', 'type': 'PROCEDURE', 'description': 'Errorless learning (EL) condition: Participant saw a picture with its name, and repeated the word. The participant continued to name the picture as the auditory cues provided less and less of the word (e.g. for "banana" she would hear "banan", "bana" then "ba" and finally no cue). If an error was produced at any stage, the whole word was presented, the participant repeated it, and the trial ended.', 'armGroupLabels': ['Errorless training condition']}]}, 'contactsLocationsModule': {'locations': [{'zip': '20057', 'city': 'Washington D.C.', 'state': 'District of Columbia', 'country': 'United States', 'facility': 'Georgetown University Medical Center', 'geoPoint': {'lat': 38.89511, 'lon': -77.03637}}], 'overallOfficials': [{'name': 'Rhonda B. Friedman, Ph.D.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Georgetown University'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Georgetown University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}