Ignite Creation Date:
2025-12-25 @ 4:06 AM
Ignite Modification Date:
2025-12-26 @ 3:02 AM
Study NCT ID:
NCT00761202
Status:
COMPLETED
Last Update Posted:
2013-11-19
First Post:
2008-09-25
Is NOT Gene Therapy:
False
Has Adverse Events:
True
Brief Title:
Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D015352', 'term': 'Dry Eye Syndromes'}], 'ancestors': [{'id': 'D007766', 'term': 'Lacrimal Apparatus Diseases'}, {'id': 'D005128', 'term': 'Eye Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D005990', 'term': 'Glycerol'}, {'id': 'D011309', 'term': 'Preservation, Biological'}, {'id': 'D006820', 'term': 'Hyaluronic Acid'}], 'ancestors': [{'id': 'D000073999', 'term': 'Triose Sugar Alcohols'}, {'id': 'D013402', 'term': 'Sugar Alcohols'}, {'id': 'D000438', 'term': 'Alcohols'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D002241', 'term': 'Carbohydrates'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D008919', 'term': 'Investigative Techniques'}, {'id': 'D006025', 'term': 'Glycosaminoglycans'}, {'id': 'D011134', 'term': 'Polysaccharides'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'clinicaltrials@allergan.com', 'phone': '(714)246-4500', 'title': 'Vice President Medical Affairs - Europe', 'organization': 'Allergan, Inc.'}, 'certainAgreement': {'restrictionType': 'LTE60', 'piSponsorEmployee': False, 'restrictiveAgreement': True}}, 'adverseEventsModule': {'eventGroups': [{'id': 'EG000', 'title': 'Carboxymethylcellulose and Glycerin', 'otherNumAtRisk': 21, 'otherNumAffected': 2, 'seriousNumAtRisk': 21, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Sodium Hyaluronate', 'otherNumAtRisk': 26, 'otherNumAffected': 2, 'seriousNumAtRisk': 26, 'seriousNumAffected': 0}], 'otherEvents': [{'term': 'Upper Lid Cyst', 'stats': [{'groupId': 'EG000', 'numAtRisk': 21, 'numAffected': 0}, {'groupId': 'EG001', 'numAtRisk': 26, 'numAffected': 1}], 'organSystem': 'Eye disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT'}, {'term': 'Mild Corneal Toxicity', 'stats': [{'groupId': 'EG000', 'numAtRisk': 21, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 26, 'numAffected': 1}], 'organSystem': 'Eye disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT'}, {'term': 'Foot Injury', 'stats': [{'groupId': 'EG000', 'numAtRisk': 21, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 26, 'numAffected': 0}], 'organSystem': 'Injury, poisoning and procedural complications', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT'}], 'frequencyThreshold': '3'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Conjunctival Staining by Lissamine Green', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'title': 'Week 1 - None', 'categories': [{'measurements': [{'value': '50.0', 'groupId': 'OG000'}, {'value': '53.8', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Trace', 'categories': [{'measurements': [{'value': '17.5', 'groupId': 'OG000'}, {'value': '15.4', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Mild', 'categories': [{'measurements': [{'value': '17.5', 'groupId': 'OG000'}, {'value': '25.0', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Moderate', 'categories': [{'measurements': [{'value': '15.0', 'groupId': 'OG000'}, {'value': '5.8', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - None', 'categories': [{'measurements': [{'value': '78.6', 'groupId': 'OG000'}, {'value': '50.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Trace', 'categories': [{'measurements': [{'value': '11.9', 'groupId': 'OG000'}, {'value': '17.3', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Mild', 'categories': [{'measurements': [{'value': '9.5', 'groupId': 'OG000'}, {'value': '25.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Moderate', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '7.7', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of cases of limbal staining by lissamine green at each point on a five point scale (0 = None, 1 = Trace, 2 = Mild, 3 = Moderate, 4 = Severe)', 'unitOfMeasure': 'Percentage of Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}, {'type': 'SECONDARY', 'title': 'Corneal Staining by Fluorescein', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'title': 'Week 1 - None', 'categories': [{'measurements': [{'value': '45.0', 'groupId': 'OG000'}, {'value': '57.7', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Trace', 'categories': [{'measurements': [{'value': '25.0', 'groupId': 'OG000'}, {'value': '15.4', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Mild', 'categories': [{'measurements': [{'value': '15.0', 'groupId': 'OG000'}, {'value': '25.0', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Moderate', 'categories': [{'measurements': [{'value': '15.0', 'groupId': 'OG000'}, {'value': '1.9', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - None', 'categories': [{'measurements': [{'value': '73.8', 'groupId': 'OG000'}, {'value': '51.9', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Trace', 'categories': [{'measurements': [{'value': '21.4', 'groupId': 'OG000'}, {'value': '15.4', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Mild', 'categories': [{'measurements': [{'value': '4.8', 'groupId': 'OG000'}, {'value': '26.9', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Moderate', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '5.8', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of cases of limbal staining by sodium fluorescein at each point on a five point scale (0 = None, 1 = Trace, 2 = Mild, 3 = Moderate, 4 = Severe)', 'unitOfMeasure': 'Percentage of Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}, {'type': 'SECONDARY', 'title': 'Conjunctival Hyperaemia', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'title': 'Week 1 - Clear/White', 'categories': [{'measurements': [{'value': '5.0', 'groupId': 'OG000'}, {'value': '3.8', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Slight', 'categories': [{'measurements': [{'value': '75.0', 'groupId': 'OG000'}, {'value': '59.6', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Mild', 'categories': [{'measurements': [{'value': '17.5', 'groupId': 'OG000'}, {'value': '36.5', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Moderate', 'categories': [{'measurements': [{'value': '2.5', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Week 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Clear/White', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Slight', 'categories': [{'measurements': [{'value': '71.4', 'groupId': 'OG000'}, {'value': '71.2', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Mild', 'categories': [{'measurements': [{'value': '28.6', 'groupId': 'OG000'}, {'value': '28.8', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Moderate', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}, {'title': 'Month 1 - Severe', 'categories': [{'measurements': [{'value': '0.0', 'groupId': 'OG000'}, {'value': '0.0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of conjunctival response reported in terms of limbal hyperaemia for the worst responses over the area at each point on a five point scale (0=clear/white conjunctiva, 1=slight redness, 2=Mild redness, 3=Moderate redness, 4=Severe redness)', 'unitOfMeasure': 'Percentage of Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}, {'type': 'SECONDARY', 'title': 'Ocular Comfort and Ocular Symptoms on Visual Analogue Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'title': 'Ocular Comfort - Waking (Wk.1)', 'categories': [{'measurements': [{'value': '67.05', 'spread': '24.90', 'groupId': 'OG000'}, {'value': '58.81', 'spread': '24.73', 'groupId': 'OG001'}]}]}, {'title': 'Ocular Comfort - Daytime (Wk.1)', 'categories': [{'measurements': [{'value': '63.20', 'spread': '22.05', 'groupId': 'OG000'}, {'value': '68.21', 'spread': '19.48', 'groupId': 'OG001'}]}]}, {'title': 'Ocular Comfort - Evening (Wk.1)', 'categories': [{'measurements': [{'value': '57.15', 'spread': '26.30', 'groupId': 'OG000'}, {'value': '63.38', 'spread': '23.71', 'groupId': 'OG001'}]}]}, {'title': 'Ocular Comfort - Waking (Mo.1)', 'categories': [{'measurements': [{'value': '65.05', 'spread': '23.48', 'groupId': 'OG000'}, {'value': '63.56', 'spread': '28.79', 'groupId': 'OG001'}]}]}, {'title': 'Ocular Comfort - Daytime (Mo.1)', 'categories': [{'measurements': [{'value': '68.57', 'spread': '17.25', 'groupId': 'OG000'}, {'value': '70.48', 'spread': '23.21', 'groupId': 'OG001'}]}]}, {'title': 'Ocular Comfort - Evening (Mo.1)', 'categories': [{'measurements': [{'value': '60.38', 'spread': '23.29', 'groupId': 'OG000'}, {'value': '65.06', 'spread': '23.44', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'week 1, month 1', 'description': 'Mean comfort judged on a 100 point visual analogue scale (0=Very Poor, 100=Excellent)', 'unitOfMeasure': 'Units on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}, {'type': 'SECONDARY', 'title': 'Daily Eyedrop Usage', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'categories': [{'measurements': [{'value': '3.7', 'spread': '1.4', 'groupId': 'OG000'}, {'value': '3.3', 'spread': '1.0', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Month 1', 'description': 'Average daily eyedrop use', 'unitOfMeasure': 'drops/day', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}, {'type': 'SECONDARY', 'title': 'Lipid Layer Pattern Assessment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'OG001', 'title': 'Sodium Hyaluronate'}], 'classes': [{'title': 'Week 1', 'categories': [{'measurements': [{'value': '4.50', 'groupId': 'OG000', 'lowerLimit': '0', 'upperLimit': '12'}, {'value': '5.50', 'groupId': 'OG001', 'lowerLimit': '1', 'upperLimit': '10'}]}]}, {'title': 'Month 1', 'categories': [{'measurements': [{'value': '3.00', 'groupId': 'OG000', 'lowerLimit': '1', 'upperLimit': '10'}, {'value': '5.00', 'groupId': 'OG001', 'lowerLimit': '1', 'upperLimit': '12'}]}]}], 'paramType': 'MEDIAN', 'timeFrame': 'Week 1, month 1', 'description': 'Lipid layer thickness as determined by lipid layer mixing pattern. A high mixing pattern = thick lipid layer.', 'unitOfMeasure': 'Lipid Layer Mixing Pattern', 'dispersionType': 'Full Range', 'reportingStatus': 'POSTED', 'populationDescription': 'Intent to Treat Population'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'FG001', 'title': 'Sodium Hyaluronate'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '22'}, {'groupId': 'FG001', 'numSubjects': '28'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '21'}, {'groupId': 'FG001', 'numSubjects': '26'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '1'}, {'groupId': 'FG001', 'numSubjects': '2'}]}]}]}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '21', 'groupId': 'BG000'}, {'value': '26', 'groupId': 'BG001'}, {'value': '47', 'groupId': 'BG002'}]}], 'groups': [{'id': 'BG000', 'title': 'Carboxymethylcellulose and Glycerin'}, {'id': 'BG001', 'title': 'Sodium Hyaluronate'}, {'id': 'BG002', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age Continuous', 'classes': [{'categories': [{'measurements': [{'value': '44.8', 'spread': '16.4', 'groupId': 'BG000'}, {'value': '39.9', 'spread': '14.8', 'groupId': 'BG001'}, {'value': '42.0', 'spread': '16.0', 'groupId': 'BG002'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '16', 'groupId': 'BG000'}, {'value': '20', 'groupId': 'BG001'}, {'value': '36', 'groupId': 'BG002'}]}, {'title': 'Male', 'measurements': [{'value': '5', 'groupId': 'BG000'}, {'value': '6', 'groupId': 'BG001'}, {'value': '11', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE4'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['INVESTIGATOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 50}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2007-08'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-10', 'completionDateStruct': {'date': '2008-06', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-10-25', 'studyFirstSubmitDate': '2008-09-25', 'resultsFirstSubmitDate': '2010-01-12', 'studyFirstSubmitQcDate': '2008-09-26', 'lastUpdatePostDateStruct': {'date': '2013-11-19', 'type': 'ESTIMATED'}, 'resultsFirstSubmitQcDate': '2010-01-12', 'studyFirstPostDateStruct': {'date': '2008-09-29', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2010-02-04', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2008-06', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Conjunctival Staining by Lissamine Green', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of cases of limbal staining by lissamine green at each point on a five point scale (0 = None, 1 = Trace, 2 = Mild, 3 = Moderate, 4 = Severe)'}], 'secondaryOutcomes': [{'measure': 'Corneal Staining by Fluorescein', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of cases of limbal staining by sodium fluorescein at each point on a five point scale (0 = None, 1 = Trace, 2 = Mild, 3 = Moderate, 4 = Severe)'}, {'measure': 'Conjunctival Hyperaemia', 'timeFrame': 'week 1, month 1', 'description': 'Percentage of conjunctival response reported in terms of limbal hyperaemia for the worst responses over the area at each point on a five point scale (0=clear/white conjunctiva, 1=slight redness, 2=Mild redness, 3=Moderate redness, 4=Severe redness)'}, {'measure': 'Ocular Comfort and Ocular Symptoms on Visual Analogue Scale', 'timeFrame': 'week 1, month 1', 'description': 'Mean comfort judged on a 100 point visual analogue scale (0=Very Poor, 100=Excellent)'}, {'measure': 'Daily Eyedrop Usage', 'timeFrame': 'Month 1', 'description': 'Average daily eyedrop use'}, {'measure': 'Lipid Layer Pattern Assessment', 'timeFrame': 'Week 1, month 1', 'description': 'Lipid layer thickness as determined by lipid layer mixing pattern. A high mixing pattern = thick lipid layer.'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Dry Eye Syndromes']}, 'descriptionModule': {'briefSummary': 'This study evaluates the performance and acceptance of Optive versus Hylocomod eyedrops, when administered for one month to patients with mild to moderate dry eye symptoms, with and without contact lenses.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* 18 years or over\n* Contact lens wearer, spectacle wearer or non-spectacle wearer\n* Mild to severe dry eye symptoms, defined as OSDI score 13 to 100\n* Mild to moderate conjunctival staining in each eye and/or mild to moderate corneal staining in each eye\n* Best corrected visual acuity of 6/9 in each eye\n\nExclusion Criteria:\n\n* Previously used Hylocomod or Optive eyedrops\n* Systemic allergy or eye allergy\n* Systemic disease which might have an ocular component and/or interfere with contact lens wear\n* Autoimmune disease which might have an ocular component and/or interfere with contact lens wear\n* Systemic medication which might have eye side effects and or interfere with contact lens wear\n* Eye infection or use of eye medication'}, 'identificationModule': {'nctId': 'NCT00761202', 'briefTitle': 'Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms', 'organization': {'class': 'INDUSTRY', 'fullName': 'Allergan'}, 'orgStudyIdInfo': {'id': 'AGN/OPH/DE/002'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': '1', 'description': 'Optive Eyedrops', 'interventionNames': ['Drug: A sterile solution containing sodium carboxymethylcellulose and glycerin, preserved with PURITE®']}, {'type': 'ACTIVE_COMPARATOR', 'label': '2', 'description': 'Hylocomod Eyedrops', 'interventionNames': ['Drug: Sodium hyaluronate']}], 'interventions': [{'name': 'A sterile solution containing sodium carboxymethylcellulose and glycerin, preserved with PURITE®', 'type': 'DRUG', 'otherNames': ['Optive™ Eyedrops'], 'description': 'Eyedrops as required, but at least 3 times per day', 'armGroupLabels': ['1']}, {'name': 'Sodium hyaluronate', 'type': 'DRUG', 'otherNames': ['Hylocomod'], 'description': 'Eyedrops as required, but at least 3 times per day', 'armGroupLabels': ['2']}]}, 'contactsLocationsModule': {'locations': [{'city': 'London', 'state': 'London', 'country': 'United Kingdom', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}], 'overallOfficials': [{'name': 'Medical Director', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Allergan'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Allergan', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}