Ignite Creation Date:
2025-12-25 @ 4:02 AM
Ignite Modification Date:
2026-02-11 @ 11:51 AM
Study NCT ID:
NCT02434302
Status:
COMPLETED
Last Update Posted:
2021-12-02
First Post:
2015-04-30
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Characteristics and Outcomes of Childhood Moyamoya in the UK
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009072', 'term': 'Moyamoya Disease'}], 'ancestors': [{'id': 'D002340', 'term': 'Carotid Artery Diseases'}, {'id': 'D002561', 'term': 'Cerebrovascular Disorders'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D002539', 'term': 'Cerebral Arterial Diseases'}, {'id': 'D020765', 'term': 'Intracranial Arterial Diseases'}, {'id': 'D001157', 'term': 'Arterial Occlusive Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 98}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2014-08'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-12', 'completionDateStruct': {'date': '2015-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-12-01', 'studyFirstSubmitDate': '2015-04-30', 'studyFirstSubmitQcDate': '2015-05-04', 'lastUpdatePostDateStruct': {'date': '2021-12-02', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2015-05-05', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2015-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Number of children with moyamoya in UK', 'timeFrame': '2 years'}], 'secondaryOutcomes': [{'measure': 'clinical features & outcomes of childhood moyamoya', 'timeFrame': '2 years'}, {'measure': 'radioplogical features of childhood Moyamoya', 'timeFrame': '2 years'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Moyamoya']}, 'descriptionModule': {'briefSummary': 'This is a study to ascertain the number of children with moyamoya in the UK, their presenting features, clinical course and outcomes.', 'detailedDescription': 'The study ahs 3 components:\n\n1. Patient identification via the British Paediatric Surveillance Unit, and the 21 collaborating centres\n2. Record review/patient interview to determine clinical features \\& outcomes\n3. Centralised review of imaging data to ascertain radiological phenotypes'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Children (0-18y) with moyamoya in the UK over study period (2014-2016 August)', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Radiological diagnosis of moyamoya\n\nExclusion Criteria:\n\n* Refuse consent'}, 'identificationModule': {'nctId': 'NCT02434302', 'briefTitle': 'Characteristics and Outcomes of Childhood Moyamoya in the UK', 'organization': {'class': 'OTHER', 'fullName': 'Great Ormond Street Hospital for Children NHS Foundation Trust'}, 'officialTitle': 'Characteristics and Outcomes of Childhood Moyamoya in the UK', 'orgStudyIdInfo': {'id': '13NR31'}}, 'contactsLocationsModule': {'locations': [{'zip': 'WC1N 3LU', 'city': 'London', 'country': 'United Kingdom', 'facility': 'Great Ormond Street Hospital for CHidlren NHS Foundation Trust', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}], 'overallOfficials': [{'name': 'vijeya ganesan, MB ChB MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'UCL Institute of Child Health'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Great Ormond Street Hospital for Children NHS Foundation Trust', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}