Ignite Creation Date:
2025-12-25 @ 4:02 AM
Ignite Modification Date:
2026-03-05 @ 12:19 AM
Study NCT ID:
NCT00626002
Status:
COMPLETED
Last Update Posted:
2013-01-30
First Post:
2008-02-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Open Label Continuation Study in Moderate to Severe Psoriasis
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'C544528', 'term': 'briakinumab'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 2301}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2008-02'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-01', 'dispFirstSubmitDate': '2012-10-05', 'completionDateStruct': {'date': '2011-10', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-01-28', 'studyFirstSubmitDate': '2008-02-22', 'dispFirstSubmitQcDate': '2012-10-05', 'studyFirstSubmitQcDate': '2008-02-22', 'dispFirstPostDateStruct': {'date': '2012-10-10', 'type': 'ESTIMATED'}, 'lastUpdatePostDateStruct': {'date': '2013-01-30', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-02-29', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Proportion of subjects achieving PGA "clear" (0) or "minimal" (1) scores by visit.', 'timeFrame': 'Visit (12 weeks)'}, {'measure': 'Proportion of subjects achieving a > PASI 50 clinical response that is defined as a reduction on PASI scores by at least 50% relative to Baseline, by visit.', 'timeFrame': 'Visit (12 weeks)'}, {'measure': 'Proportion of subjects achieving a > PASI 75 clinical response that is defined as a reduction on PASI scores by at least 50% relative to Baseline, by visit.', 'timeFrame': 'Visit (12 weeks)'}, {'measure': 'AEs, serious adverse events (SAEs), laboratory data, ADA and vital signs will be assessed throughout the study', 'timeFrame': 'Visit (12 weeks)'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Open label'], 'conditions': ['Moderate to Severe Plaque Psoriasis']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to evaluate long term safety, efficacy and tolerability of ABT-874 in adults with moderate to severe psoriasis.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Having participated in a preceding ABT-874 clinical trial for ABT-874\n* Subject has a clinical diagnosis of moderate to severe plaque psoriasis\n\nExclusion Criteria:\n\n* Subjects who prematurely discontinued in any preceding psoriasis study with ABT-874 other than protocol-required discontinuation'}, 'identificationModule': {'nctId': 'NCT00626002', 'briefTitle': 'Open Label Continuation Study in Moderate to Severe Psoriasis', 'organization': {'class': 'INDUSTRY', 'fullName': 'AbbVie'}, 'officialTitle': 'A Phase 3, Multi-center, Open-label Continuation Study in Moderate to Severe Plaque Psoriasis in Subjects Who Completed a Preceding Psoriasis Study With ABT-874', 'orgStudyIdInfo': {'id': 'M10-016'}, 'secondaryIdInfos': [{'id': '2007-005955-40', 'type': 'EUDRACT_NUMBER'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': '1', 'interventionNames': ['Drug: ABT-874']}], 'interventions': [{'name': 'ABT-874', 'type': 'DRUG', 'otherNames': ['briakinumab'], 'description': '100mg ABT-874 administered SQ every 4 wks for approximately 204 weeks', 'armGroupLabels': ['1']}]}, 'contactsLocationsModule': {'locations': [{'zip': '35205', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7496', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '35233', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8438', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '35801', 'city': 'Huntsville', 'state': 'Alabama', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7522', 'geoPoint': {'lat': 34.7304, 'lon': -86.58594}}, {'zip': '85251', 'city': 'Scottsdale', 'state': 'Arizona', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7774', 'geoPoint': {'lat': 33.50921, 'lon': -111.89903}}, {'zip': '85710', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7435', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '72204', 'city': 'Little Rock', 'state': 'Arkansas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7933', 'geoPoint': {'lat': 34.74648, 'lon': -92.28959}}, {'zip': '93309', 'city': 'Bakersfield', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7234', 'geoPoint': {'lat': 35.37329, 'lon': -119.01871}}, {'zip': '93720', 'city': 'Fresno', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8249', 'geoPoint': {'lat': 36.74773, 'lon': -119.77237}}, {'zip': '92697', 'city': 'Irvine', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7332', 'geoPoint': {'lat': 33.66946, 'lon': -117.82311}}, {'zip': '90045', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7239', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '92056', 'city': 'Oceanside', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8390', 'geoPoint': {'lat': 33.19587, 'lon': -117.37948}}, {'zip': '92103', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7503', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '92117', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7520', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '92123', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7010', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '94118', 'city': 'San Francisco', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10962', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}, {'zip': '90404', 'city': 'Santa Monica', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7334', 'geoPoint': {'lat': 34.01949, 'lon': -118.49138}}, {'zip': '94589', 'city': 'Vallejo', 'state': 'California', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7793', 'geoPoint': {'lat': 38.10409, 'lon': -122.25664}}, {'zip': '80209', 'city': 'Denver', 'state': 'Colorado', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7929', 'geoPoint': {'lat': 39.73915, 'lon': -104.9847}}, {'zip': '80501', 'city': 'Longmont', 'state': 'Colorado', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7436', 'geoPoint': {'lat': 40.16721, 'lon': -105.10193}}, {'zip': '06511', 'city': 'New Haven', 'state': 'Connecticut', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7521', 'geoPoint': {'lat': 41.30815, 'lon': -72.92816}}, {'zip': '33166-6665', 'city': 'Doral', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7653', 'geoPoint': {'lat': 25.81954, 'lon': -80.35533}}, {'zip': '32204', 'city': 'Jacksonville', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8341', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '33136', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7716', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33144', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7657', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33143', 'city': 'South Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10841', 'geoPoint': {'lat': 25.7076, 'lon': -80.29338}}, {'zip': '33409-3509', 'city': 'West Palm Beach', 'state': 'Florida', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7893', 'geoPoint': {'lat': 26.71534, 'lon': -80.05337}}, {'zip': '30022', 'city': 'Alpharetta', 'state': 'Georgia', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7331', 'geoPoint': {'lat': 34.07538, 'lon': -84.29409}}, {'zip': '30327', 'city': 'Atlanta', 'state': 'Georgia', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 9743', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30263', 'city': 'Newnan', 'state': 'Georgia', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7891', 'geoPoint': {'lat': 33.38067, 'lon': -84.79966}}, {'zip': '30078', 'city': 'Snellville', 'state': 'Georgia', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7932', 'geoPoint': {'lat': 33.85733, 'lon': -84.01991}}, {'zip': '60005', 'city': 'Arlington Heights', 'state': 'Illinois', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8379', 'geoPoint': {'lat': 42.08836, 'lon': -87.98063}}, {'zip': '60153', 'city': 'Maywood', 'state': 'Illinois', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8798', 'geoPoint': {'lat': 41.8792, 'lon': -87.84312}}, {'zip': '60194', 'city': 'Schaumburg', 'state': 'Illinois', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10703', 'geoPoint': {'lat': 42.03336, 'lon': -88.08341}}, {'zip': '60077', 'city': 'Skokie', 'state': 'Illinois', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6950', 'geoPoint': {'lat': 42.03336, 'lon': -87.73339}}, {'zip': '60118', 'city': 'West Dundee', 'state': 'Illinois', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7892', 'geoPoint': {'lat': 42.09808, 'lon': -88.28286}}, {'zip': '46256', 'city': 'Indianapolis', 'state': 'Indiana', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6933', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46260', 'city': 'Indianapolis', 'state': 'Indiana', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10422', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46168', 'city': 'Plainfield', 'state': 'Indiana', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 16581', 'geoPoint': {'lat': 39.70421, 'lon': -86.39944}}, {'zip': '66202', 'city': 'Overland Park', 'state': 'Kansas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7992', 'geoPoint': {'lat': 38.98223, 'lon': -94.67079}}, {'zip': '42420', 'city': 'Henderson', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 17193', 'geoPoint': {'lat': 37.83615, 'lon': -87.59001}}, {'zip': '40202', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8528', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '42303', 'city': 'Owensboro', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 9962', 'geoPoint': {'lat': 37.77422, 'lon': -87.11333}}, {'zip': '01810', 'city': 'Andover', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8529', 'geoPoint': {'lat': 42.65843, 'lon': -71.137}}, {'zip': '02111', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8149', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '48202', 'city': 'Detroit', 'state': 'Michigan', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 9823', 'geoPoint': {'lat': 42.33143, 'lon': -83.04575}}, {'zip': '48059', 'city': 'Fort Gratiot', 'state': 'Michigan', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7883'}, {'zip': '48439', 'city': 'Grand Blanc', 'state': 'Michigan', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7238', 'geoPoint': {'lat': 42.92753, 'lon': -83.62995}}, {'zip': '55432', 'city': 'Fridley', 'state': 'Minnesota', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7656', 'geoPoint': {'lat': 45.08608, 'lon': -93.26328}}, {'zip': '63110', 'city': 'St Louis', 'state': 'Missouri', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6930', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '63117', 'city': 'St Louis', 'state': 'Missouri', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6949', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '68131', 'city': 'Omaha', 'state': 'Nebraska', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7240', 'geoPoint': {'lat': 41.25626, 'lon': -95.94043}}, {'zip': '68144', 'city': 'Omaha', 'state': 'Nebraska', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 9567', 'geoPoint': {'lat': 41.25626, 'lon': -95.94043}}, {'zip': '08009', 'city': 'Berlin', 'state': 'New Jersey', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7757', 'geoPoint': {'lat': 39.79123, 'lon': -74.92905}}, {'zip': '08520', 'city': 'East Windsor', 'state': 'New Jersey', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7330', 'geoPoint': {'lat': 40.268, 'lon': -74.54043}}, {'zip': '08903', 'city': 'New Brunswick', 'state': 'New Jersey', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7882', 'geoPoint': {'lat': 40.48622, 'lon': -74.45182}}, {'zip': '87106', 'city': 'Albuquerque', 'state': 'New Mexico', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7455', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '14221', 'city': 'Buffalo', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8078', 'geoPoint': {'lat': 42.88645, 'lon': -78.87837}}, {'zip': '10016', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8392', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10025', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8006', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10029-6501', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7230', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10032', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10201', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '14623', 'city': 'Rochester', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8037', 'geoPoint': {'lat': 43.15478, 'lon': -77.61556}}, {'zip': '11790', 'city': 'Stoney Brook', 'state': 'New York', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7333'}, {'zip': '28602', 'city': 'Hickory', 'state': 'North Carolina', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7434', 'geoPoint': {'lat': 35.73319, 'lon': -81.3412}}, {'zip': '28401', 'city': 'Wilmington', 'state': 'North Carolina', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8117', 'geoPoint': {'lat': 34.23556, 'lon': -77.94604}}, {'zip': '27157', 'city': 'Winston-Salem', 'state': 'North Carolina', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 9681', 'geoPoint': {'lat': 36.09986, 'lon': -80.24422}}, {'zip': '45219', 'city': 'Cincinnati', 'state': 'Ohio', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6945', 'geoPoint': {'lat': 39.12711, 'lon': -84.51439}}, {'zip': '45220', 'city': 'Cincinnati', 'state': 'Ohio', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 23345', 'geoPoint': {'lat': 39.12711, 'lon': -84.51439}}, {'zip': '44106', 'city': 'Cleveland', 'state': 'Ohio', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7044', 'geoPoint': {'lat': 41.4995, 'lon': -81.69541}}, {'zip': '43212', 'city': 'Columbus', 'state': 'Ohio', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7899', 'geoPoint': {'lat': 39.96118, 'lon': -82.99879}}, {'zip': '45408', 'city': 'Dayton', 'state': 'Ohio', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8389', 'geoPoint': {'lat': 39.75895, 'lon': -84.19161}}, {'zip': '73104', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 11181', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '97035', 'city': 'Lake Oswego', 'state': 'Oregon', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6936', 'geoPoint': {'lat': 45.42067, 'lon': -122.67065}}, {'zip': '97210', 'city': 'Portland', 'state': 'Oregon', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7703', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97223', 'city': 'Portland', 'state': 'Oregon', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6948', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97239', 'city': 'Portland', 'state': 'Oregon', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 11424', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '17033', 'city': 'Hershey', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8494', 'geoPoint': {'lat': 40.28592, 'lon': -76.65025}}, {'zip': '19103', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7930', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '02919', 'city': 'Johnston', 'state': 'Rhode Island', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6934', 'geoPoint': {'lat': 41.82186, 'lon': -71.50675}}, {'zip': '02903', 'city': 'Providence', 'state': 'Rhode Island', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6935', 'geoPoint': {'lat': 41.82399, 'lon': -71.41283}}, {'zip': '29650', 'city': 'Greer', 'state': 'South Carolina', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7785', 'geoPoint': {'lat': 34.93873, 'lon': -82.22706}}, {'zip': '37072', 'city': 'Goodlettsville', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7497', 'geoPoint': {'lat': 36.32311, 'lon': -86.71333}}, {'zip': '37934', 'city': 'Knoxville', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7388', 'geoPoint': {'lat': 35.96064, 'lon': -83.92074}}, {'zip': '37215', 'city': 'Nashville', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6931', 'geoPoint': {'lat': 36.16589, 'lon': -86.78444}}, {'zip': '76011', 'city': 'Arlington', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7684', 'geoPoint': {'lat': 32.73569, 'lon': -97.10807}}, {'zip': '78759', 'city': 'Austin', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10842', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '75230', 'city': 'Dallas', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7498', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '75246-1613', 'city': 'Dallas', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6947', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '77030', 'city': 'Houston', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6944', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '78229', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7758', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '78229', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 8108', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '75703', 'city': 'Tyler', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6937', 'geoPoint': {'lat': 32.35126, 'lon': -95.30106}}, {'zip': '77598', 'city': 'Webster', 'state': 'Texas', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7655', 'geoPoint': {'lat': 29.53773, 'lon': -95.11826}}, {'zip': '84132', 'city': 'Salt Lake City', 'state': 'Utah', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10207', 'geoPoint': {'lat': 40.76078, 'lon': -111.89105}}, {'zip': '23507', 'city': 'Norfolk', 'state': 'Virginia', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6946', 'geoPoint': {'lat': 36.84681, 'lon': -76.28522}}, {'zip': '98101', 'city': 'Seattle', 'state': 'Washington', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 6932', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '99204', 'city': 'Spokane', 'state': 'Washington', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 10306', 'geoPoint': {'lat': 47.65966, 'lon': -117.42908}}, {'zip': '53209', 'city': 'Milwaukee', 'state': 'Wisconsin', 'country': 'United States', 'facility': 'Site Reference ID/Investigator# 7884', 'geoPoint': {'lat': 43.0389, 'lon': -87.90647}}, {'zip': '8036', 'city': 'Graz', 'country': 'Austria', 'facility': 'Site Reference ID/Investigator# 16845', 'geoPoint': {'lat': 47.06733, 'lon': 15.44197}}, {'zip': '1090', 'city': 'Vienna', 'country': 'Austria', 'facility': 'Site Reference ID/Investigator# 18183', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': '1200', 'city': 'Brussels', 'country': 'Belgium', 'facility': 'Site Reference ID/Investigator# 15761', 'geoPoint': {'lat': 50.85045, 'lon': 4.34878}}, {'zip': 'L4M 6L2', 'city': 'Barrie', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7991', 'geoPoint': {'lat': 44.40011, 'lon': -79.66634}}, {'zip': 'T3G 0B4', 'city': 'Calgary', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8047', 'geoPoint': {'lat': 51.05011, 'lon': -114.08529}}, {'zip': 'T5K 1X3', 'city': 'Edmonton', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7996', 'geoPoint': {'lat': 53.55014, 'lon': -113.46871}}, {'zip': 'B3H 0A2', 'city': 'Halifax', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6996', 'geoPoint': {'lat': 44.64269, 'lon': -63.57688}}, {'zip': 'L8N 1V6', 'city': 'Hamilton', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7236', 'geoPoint': {'lat': 43.25011, 'lon': -79.84963}}, {'zip': 'H7S 2C6', 'city': 'Laval', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6995', 'geoPoint': {'lat': 45.56995, 'lon': -73.692}}, {'zip': 'N5X 2P1', 'city': 'London', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6998', 'geoPoint': {'lat': 42.98339, 'lon': -81.23304}}, {'zip': 'N6A 3H7', 'city': 'London', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7043', 'geoPoint': {'lat': 42.98339, 'lon': -81.23304}}, {'zip': 'L3P 1A8', 'city': 'Markham', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7329', 'geoPoint': {'lat': 43.86682, 'lon': -79.2663}}, {'zip': 'H2K 4L5', 'city': 'Montreal', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6999', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'zip': 'H3H 1V4', 'city': 'Montreal', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7652', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'zip': 'P1B 3Z7', 'city': 'North Bay', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7006', 'geoPoint': {'lat': 46.3168, 'lon': -79.46633}}, {'zip': 'K2G 6E2', 'city': 'Ottawa', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8102', 'geoPoint': {'lat': 45.41117, 'lon': -75.69812}}, {'zip': 'G1V 4X7', 'city': 'Québec', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6993', 'geoPoint': {'lat': 46.81228, 'lon': -71.21454}}, {'zip': 'A1A 5E8', 'city': "St. John's", 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8112', 'geoPoint': {'lat': 47.56494, 'lon': -52.70931}}, {'zip': 'V3R 6A7', 'city': 'Surrey', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7931', 'geoPoint': {'lat': 49.10635, 'lon': -122.82509}}, {'zip': 'V5Z 3Y1', 'city': 'Vancouver', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8118', 'geoPoint': {'lat': 49.24966, 'lon': -123.11934}}, {'zip': 'V5Z 4E8', 'city': 'Vancouver', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6997', 'geoPoint': {'lat': 49.24966, 'lon': -123.11934}}, {'zip': 'N2J 1C4', 'city': 'Waterloo', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 6994', 'geoPoint': {'lat': 43.4668, 'lon': -80.51639}}, {'zip': 'H3Z 2S6', 'city': 'Westmount', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8111', 'geoPoint': {'lat': 45.48341, 'lon': -73.59918}}, {'zip': 'N8W 1E6', 'city': 'Windsor', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7005', 'geoPoint': {'lat': 42.30008, 'lon': -83.01654}}, {'zip': 'N8W 5L7', 'city': 'Windsor', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 7979', 'geoPoint': {'lat': 42.30008, 'lon': -83.01654}}, {'zip': 'R3C 1R4', 'city': 'Winnipeg', 'country': 'Canada', 'facility': 'Site Reference ID/Investigator# 8348', 'geoPoint': {'lat': 49.8844, 'lon': -97.14704}}, {'zip': '8000', 'city': 'Aarhus', 'country': 'Denmark', 'facility': 'Site Reference ID/Investigator# 17781', 'geoPoint': {'lat': 56.15674, 'lon': 10.21076}}, {'zip': '2400', 'city': 'Copenhagen NV', 'country': 'Denmark', 'facility': 'Site Reference ID/Investigator# 18041'}, {'zip': '00029 HUS', 'city': 'Helsinki', 'country': 'Finland', 'facility': 'Site Reference ID/Investigator# 18661', 'geoPoint': {'lat': 60.16952, 'lon': 24.93545}}, {'zip': '70210', 'city': 'Kuopio', 'country': 'Finland', 'facility': 'Site Reference ID/Investigator# 18701', 'geoPoint': {'lat': 62.89238, 'lon': 27.67703}}, {'zip': '15850', 'city': 'Lahti', 'country': 'Finland', 'facility': 'Site Reference ID/Investigator# 14962', 'geoPoint': {'lat': 60.98267, 'lon': 25.66151}}, {'zip': '20521', 'city': 'Turku', 'country': 'Finland', 'facility': 'Site Reference ID/Investigator# 19241', 'geoPoint': {'lat': 60.45148, 'lon': 22.26869}}, {'zip': '06200', 'city': 'Nice', 'country': 'France', 'facility': 'Site Reference ID/Investigator# 18502', 'geoPoint': {'lat': 43.70313, 'lon': 7.26608}}, {'zip': '75475', 'city': 'Paris', 'country': 'France', 'facility': 'Site Reference ID/Investigator# 16781', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}, {'zip': '31059', 'city': 'Toulouse', 'country': 'France', 'facility': 'Site Reference ID/Investigator# 18506', 'geoPoint': {'lat': 43.60426, 'lon': 1.44367}}, {'zip': '10117', 'city': 'Berlin', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 16281', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '60590', 'city': 'Frankfurt am Main', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 15664', 'geoPoint': {'lat': 50.11552, 'lon': 8.68417}}, {'zip': 'D-20354', 'city': 'Hamburg', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 15663', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '24105', 'city': 'Kiel', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 16381', 'geoPoint': {'lat': 54.32133, 'lon': 10.13489}}, {'zip': 'D-80337', 'city': 'Munich', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 16143', 'geoPoint': {'lat': 48.13743, 'lon': 11.57549}}, {'zip': '48149', 'city': 'Münster', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 16161', 'geoPoint': {'lat': 51.96236, 'lon': 7.62571}}, {'zip': '72076', 'city': 'Tübingen', 'country': 'Germany', 'facility': 'Site Reference ID/Investigator# 17676', 'geoPoint': {'lat': 48.52266, 'lon': 9.05222}}, {'zip': '161 21', 'city': 'Athens', 'country': 'Greece', 'facility': 'Site Reference ID/Investigator# 16282', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': '16121', 'city': 'Athens', 'country': 'Greece', 'facility': 'Site Reference ID/Investigator# 15921', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': '54643', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': 'Site Reference ID/Investigator# 15922', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '41100', 'city': 'Modena', 'country': 'Italy', 'facility': 'Site Reference ID/Investigator# 15401', 'geoPoint': {'lat': 44.64783, 'lon': 10.92539}}, {'zip': '00133', 'city': 'Rome', 'country': 'Italy', 'facility': 'Site Reference ID/Investigator# 14881', 'geoPoint': {'lat': 41.89193, 'lon': 12.51133}}, {'zip': '08916', 'city': 'Barcelona', 'country': 'Spain', 'facility': 'Site Reference ID/Investigator# 19322', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '28006', 'city': 'Madrid', 'country': 'Spain', 'facility': 'Site Reference ID/Investigator# 15341', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '171 76', 'city': 'Stockholm', 'country': 'Sweden', 'facility': 'Site Reference ID/Investigator# 16142', 'geoPoint': {'lat': 59.32938, 'lon': 18.06871}}, {'zip': '1211', 'city': 'Geneva', 'country': 'Switzerland', 'facility': 'Site Reference ID/Investigator# 17721', 'geoPoint': {'lat': 46.20222, 'lon': 6.14569}}, {'zip': '8091', 'city': 'Zurich', 'country': 'Switzerland', 'facility': 'Site Reference ID/Investigator# 16749', 'geoPoint': {'lat': 47.36667, 'lon': 8.55}}, {'zip': 'AB25 2ZR', 'city': 'Aberdeen', 'country': 'United Kingdom', 'facility': 'Site Reference ID/Investigator# 19045', 'geoPoint': {'lat': 57.14369, 'lon': -2.09814}}, {'zip': 'M6 8HD', 'city': 'Manchester', 'country': 'United Kingdom', 'facility': 'Site Reference ID/Investigator# 15422', 'geoPoint': {'lat': 53.48095, 'lon': -2.23743}}], 'overallOfficials': [{'name': 'Martin Kaul, MD', 'role': 'STUDY_CHAIR', 'affiliation': 'AbbVie'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'AbbVie (prior sponsor, Abbott)', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}