Ignite Creation Date:
2025-12-25 @ 3:57 AM
Ignite Modification Date:
2025-12-26 @ 2:49 AM
Study NCT ID:
NCT00163202
Status:
COMPLETED
Last Update Posted:
2021-02-18
First Post:
2005-09-09
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Comparative Atorvastatin Pleiotropic Effects
Sponsor:
Organization:
Raw JSON
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Comparative effects of 10-mg versus 80-mg Atorvastatin on high-sensitivity C-reactive protein in patients with stable coronary artery disease: results of the CAP (Comparative Atorvastatin Pleiotropic effects) study. Clin Ther. 2008 Dec;30(12):2298-313. doi: 10.1016/j.clinthera.2008.12.023.'}]}, 'descriptionModule': {'briefSummary': 'The primary objective of the study is to evaluate the efficacy of atorvastatin 80 mg daily as compared to atorvastatin 10 mg daily in reducing C-reactive protein levels over a 26-week treatment period in subjects with documented coronary artery disease.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Male or female subjects of age of majority to \\< 80 years\n* Subjects with LDL-C \\> 0.5 g/L (1.29 mmol/L) and \\< 1.5 g/L (3.87 mmol/L), TG \\< 4.00 g/L (4.56 mmol/L) and hs-CRP \\>1.5 mg/L and \\< 15 mg/L\n* Subjects with a documented coronary artery disease.\n\nExclusion Criteria:\n\n* Female subjects of childbearing potential without contraception\n* Subjects with secondary hyperlipidemia\n* Diabetic subjects 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