Ignite Creation Date:
2025-12-25 @ 3:56 AM
Ignite Modification Date:
2025-12-26 @ 2:46 AM
Study NCT ID:
NCT01699802
Status:
COMPLETED
Last Update Posted:
2015-05-14
First Post:
2012-09-25
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D017202', 'term': 'Myocardial Ischemia'}], 'ancestors': [{'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NA', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 12}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2012-09'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2015-05', 'completionDateStruct': {'date': '2014-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2015-05-13', 'studyFirstSubmitDate': '2012-09-25', 'studyFirstSubmitQcDate': '2012-10-01', 'lastUpdatePostDateStruct': {'date': '2015-05-14', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2012-10-04', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2014-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Volume of carbon dioxide rebreathing from an anesthetic gas reflector', 'timeFrame': '2 hours', 'description': 'Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.'}], 'secondaryOutcomes': [{'measure': 'Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector.', 'timeFrame': '2 hours', 'description': 'Changes of tidal volume required to maintain constant alveolar ventilation will be assessed by continuous measurement of exhaled tidal carbon dioxide volume, the latter to be maintained at a constant value.'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Ischemic Heart Disease']}, 'descriptionModule': {'briefSummary': 'The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent.\n\nThe hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '90 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* elective coronary artery by-pass graft surgery\n* elective valve replacement surgery\n* normal left ventricular ejection fraction on preoperative echocardiography\n\nExclusion Criteria:\n\n* obstructive lung disease\n* restrictive lung disease'}, 'identificationModule': {'nctId': 'NCT01699802', 'briefTitle': 'Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)', 'organization': {'class': 'OTHER', 'fullName': 'Region Skane'}, 'officialTitle': 'Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)', 'orgStudyIdInfo': {'id': '2012/148'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Inhaled anaesthetic agent', 'description': 'The group where the investigators adds inhaled anaesthetic agent when using the anaesthetic gas reflector (AnaConda).', 'interventionNames': ['Other: Inhaled anaesthetic agent']}], 'interventions': [{'name': 'Inhaled anaesthetic agent', 'type': 'OTHER', 'armGroupLabels': ['Inhaled anaesthetic agent']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'SE-221 85', 'city': 'Lund', 'country': 'Sweden', 'facility': 'Skane University Hospital Lund, Cardiothoracic Intensive Care', 'geoPoint': {'lat': 55.70584, 'lon': 13.19321}}], 'overallOfficials': [{'name': 'Mikael Bodelsson, Professor', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Divison of Surgery, Department of Anaesthesia, Skane University Hospital, Lund, Sweden'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Region Skane', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}