Ignite Creation Date:
2025-12-25 @ 3:56 AM
Ignite Modification Date:
2025-12-26 @ 2:46 AM
Study NCT ID:
NCT04532502
Status:
COMPLETED
Last Update Posted:
2021-12-03
First Post:
2020-08-25
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Impact of Anesthetic Environment the Sex Ratio of the Children of Female Assistants
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D018685', 'term': 'Anesthetics, Inhalation'}], 'ancestors': [{'id': 'D018681', 'term': 'Anesthetics, General'}, {'id': 'D000777', 'term': 'Anesthetics'}, {'id': 'D002492', 'term': 'Central Nervous System Depressants'}, {'id': 'D045505', 'term': 'Physiological Effects of Drugs'}, {'id': 'D020228', 'term': 'Pharmacologic Actions'}, {'id': 'D020164', 'term': 'Chemical Actions and Uses'}, {'id': 'D002491', 'term': 'Central Nervous System Agents'}, {'id': 'D045506', 'term': 'Therapeutic Uses'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 143}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2021-10-02', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-12', 'completionDateStruct': {'date': '2021-12-02', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-12-02', 'studyFirstSubmitDate': '2020-08-25', 'studyFirstSubmitQcDate': '2020-08-25', 'lastUpdatePostDateStruct': {'date': '2021-12-03', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2020-08-31', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-12-02', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Offspring sex ratio', 'timeFrame': '5 years (duration of anesthesia training)', 'description': 'Offspring sex ratio of female anesthesia assistants will be recorded'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Anesthesia care providers', 'offspring sex ratio', 'Inhalation induction of anesthesia'], 'conditions': ['Anesthesia, General', 'Anesthetics Adverse Reaction']}, 'referencesModule': {'references': [{'pmid': '23878446', 'type': 'BACKGROUND', 'citation': 'Gupta D, Kaminski E, McKelvey G, Wang H. Firstborn offspring sex ratio is skewed towards female offspring in anesthesia care providers: A questionnaire-based nationwide study from United States. J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):221-7. doi: 10.4103/0970-9185.111728.'}, {'type': 'BACKGROUND', 'citation': "Leroy C, Daelemans C, Debauche C, Van Leeuw V. Santé périnatale en Wallonie - année 2017, Centre d'Epidémiologie Périnatale 2019."}]}, 'descriptionModule': {'briefSummary': "The aims of this multi center retrospective study was to determine:\n\n* whether the sex ratio of the offspring of female assistants in anesthesia-resuscitation differs from that of the population at large\n* whether the assistants' work environment at the time of their offspring's conception influences the sex of their offspring"}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'The anesthesia department of the three French-speaking universities in Belgium wimp e-mail a questionnaire to all female assistants in anesthesia-resuscitation via a system similar to Survey Monkey. The data will be completely anonymized through those of such a system.\n\nReminder will be e-mailed 1 and 3 months after the questionnaire is sent out. Filling the questionnaire will be equated with consent', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Female assistants in anesthesia-resuscitation in the Wallonia-Brussels Federation (Belgium) who conceived one or more children in the course of their training between 2009 and 2019 and who delivered before the end of 2019 (cut-off: midnight on 31 December 2019)\n\nExclusion Criteria:\n\n* Male assistants in anesthesia-resuscitation\n* Female assistants in anesthesia-resuscitation who trained before 2009 or after 2019.\n* Female assistants in anesthesia-resuscitation who relied on medically assisted reproduction.'}, 'identificationModule': {'nctId': 'NCT04532502', 'briefTitle': 'Impact of Anesthetic Environment the Sex Ratio of the Children of Female Assistants', 'organization': {'class': 'OTHER', 'fullName': 'University of Liege'}, 'officialTitle': "Work Environment's Impact on the Sex Ratio of the Children of Resuscitation Anesthesia Assistants", 'orgStudyIdInfo': {'id': 'GENREANES'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Study group', 'description': 'All female assistants in anesthesia', 'interventionNames': ['Drug: Anesthetics, Inhalation']}], 'interventions': [{'name': 'Anesthetics, Inhalation', 'type': 'DRUG', 'description': 'Work environmental exposure', 'armGroupLabels': ['Study group']}]}, 'contactsLocationsModule': {'locations': [{'zip': '4000', 'city': 'Liège', 'country': 'Belgium', 'facility': 'ULiege', 'geoPoint': {'lat': 50.63373, 'lon': 5.56749}}], 'overallOfficials': [{'name': 'Philippe J Van der Linden, MD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'CHU Brugmann, Free University of Brussels, Belgium'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Liege', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Jean François Brichant', 'investigatorAffiliation': 'University of Liege'}}}}