Ignite Creation Date:
2025-12-25 @ 3:47 AM
Ignite Modification Date:
2025-12-26 @ 2:34 AM
Study NCT ID:
NCT06911502
Status:
RECRUITING
Last Update Posted:
2025-12-05
First Post:
2025-03-28
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D008224', 'term': 'Lymphoma, Follicular'}], 'ancestors': [{'id': 'D008228', 'term': 'Lymphoma, Non-Hodgkin'}, {'id': 'D008223', 'term': 'Lymphoma'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D008232', 'term': 'Lymphoproliferative Disorders'}, {'id': 'D008206', 'term': 'Lymphatic Diseases'}, {'id': 'D006425', 'term': 'Hemic and Lymphatic Diseases'}, {'id': 'D007160', 'term': 'Immunoproliferative Disorders'}, {'id': 'D007154', 'term': 'Immune System Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D000069283', 'term': 'Rituximab'}, {'id': 'D000077269', 'term': 'Lenalidomide'}, {'id': 'D003520', 'term': 'Cyclophosphamide'}, {'id': 'D004317', 'term': 'Doxorubicin'}, {'id': 'D014750', 'term': 'Vincristine'}, {'id': 'D011241', 'term': 'Prednisone'}, {'id': 'D011239', 'term': 'Prednisolone'}, {'id': 'D000069461', 'term': 'Bendamustine Hydrochloride'}], 'ancestors': [{'id': 'D058846', 'term': 'Antibodies, Monoclonal, Murine-Derived'}, {'id': 'D000911', 'term': 'Antibodies, Monoclonal'}, {'id': 'D000906', 'term': 'Antibodies'}, {'id': 'D007136', 'term': 'Immunoglobulins'}, {'id': 'D007162', 'term': 'Immunoproteins'}, {'id': 'D001798', 'term': 'Blood Proteins'}, {'id': 'D011506', 'term': 'Proteins'}, {'id': 'D000602', 'term': 'Amino Acids, Peptides, and Proteins'}, {'id': 'D012712', 'term': 'Serum Globulins'}, {'id': 'D005916', 'term': 'Globulins'}, {'id': 'D010797', 'term': 'Phthalimides'}, {'id': 'D010795', 'term': 'Phthalic Acids'}, {'id': 'D000146', 'term': 'Acids, Carbocyclic'}, {'id': 'D002264', 'term': 'Carboxylic Acids'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D010881', 'term': 'Piperidones'}, {'id': 'D010880', 'term': 'Piperidines'}, {'id': 'D006573', 'term': 'Heterocyclic Compounds, 1-Ring'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}, {'id': 'D054833', 'term': 'Isoindoles'}, {'id': 'D006574', 'term': 'Heterocyclic Compounds, 2-Ring'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}, {'id': 'D010752', 'term': 'Phosphoramide Mustards'}, {'id': 'D009588', 'term': 'Nitrogen Mustard Compounds'}, {'id': 'D009150', 'term': 'Mustard Compounds'}, {'id': 'D006846', 'term': 'Hydrocarbons, Halogenated'}, {'id': 'D006838', 'term': 'Hydrocarbons'}, {'id': 'D063088', 'term': 'Phosphoramides'}, {'id': 'D009943', 'term': 'Organophosphorus Compounds'}, {'id': 'D003630', 'term': 'Daunorubicin'}, {'id': 'D018943', 'term': 'Anthracyclines'}, {'id': 'D009279', 'term': 'Naphthacenes'}, {'id': 'D011084', 'term': 'Polycyclic Aromatic Hydrocarbons'}, {'id': 'D006841', 'term': 'Hydrocarbons, Aromatic'}, {'id': 'D006844', 'term': 'Hydrocarbons, Cyclic'}, {'id': 'D011083', 'term': 'Polycyclic Compounds'}, {'id': 'D000617', 'term': 'Aminoglycosides'}, {'id': 'D006027', 'term': 'Glycosides'}, {'id': 'D002241', 'term': 'Carbohydrates'}, {'id': 'D014748', 'term': 'Vinca Alkaloids'}, {'id': 'D046948', 'term': 'Secologanin Tryptamine Alkaloids'}, {'id': 'D026121', 'term': 'Indole Alkaloids'}, {'id': 'D000470', 'term': 'Alkaloids'}, {'id': 'D007211', 'term': 'Indoles'}, {'id': 'D054836', 'term': 'Indolizidines'}, {'id': 'D007212', 'term': 'Indolizines'}, {'id': 'D011244', 'term': 'Pregnadienediols'}, {'id': 'D011245', 'term': 'Pregnadienes'}, {'id': 'D011278', 'term': 'Pregnanes'}, {'id': 'D013256', 'term': 'Steroids'}, {'id': 'D000072473', 'term': 'Fused-Ring Compounds'}, {'id': 'D011246', 'term': 'Pregnadienetriols'}, {'id': 'D002087', 'term': 'Butyrates'}, {'id': 'D000144', 'term': 'Acids, Acyclic'}, {'id': 'D001562', 'term': 'Benzimidazoles'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 400}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2025-07-28', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2030-07-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-04', 'studyFirstSubmitDate': '2025-03-28', 'studyFirstSubmitQcDate': '2025-03-28', 'lastUpdatePostDateStruct': {'date': '2025-12-05', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2025-04-04', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2028-04-24', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Progression free survival (PFS) assessed by Independent Review Adjudication committee (IRAC)', 'timeFrame': 'Up to approximately 32 Months'}], 'secondaryOutcomes': [{'measure': 'Overall response rate (ORR) assessed by IRAC', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Overall survival (OS)', 'timeFrame': 'Up to approximately 83 Months'}, {'measure': 'PFS as assessed by investigator', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'ORR as assessed by investigator', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Number of participants who achieve complete metabolic response (CMR)', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Duration of Response (DoR)', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Event free survival (EFS)', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Time to next anti-lymphoma treatment (TTNT)', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'PFS on next anti-lymphoma treatment (PFS2)', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Time from randomization to meaningful improvement in primary domains of interest in the European Organization for Research and Treatment of Cancer - Quality of Life C30 (EORTC QLQ-C30) Questionnaire', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Time from randomization to meaningful improvement in primary domains of interest in the European Organization for Research and Treatment of Cancer - Non- Hodgkin Lymphoma- Low Grade- 20 items (EORTC QLQNHL- LG20) Questionnaire', 'timeFrame': 'Up to approximately 32 Months'}, {'measure': 'Minimal residual disease (MRD) negativity', 'timeFrame': 'Up to approximately 32 Months'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Follicular Lymphoma', 'Second Line Follicular Lymphoma', 'Third Line Follicular Lymphoma', 'Relapsed/refractory follicular lymphoma'], 'conditions': ['Follicular Lymphoma']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html', 'label': 'BMS Clinical Trial Information'}, {'url': 'https://www.bmsclinicaltrials.com/us/en/clinical-trials/NCT06911502.html', 'label': 'BMS Clinical Trial Patient Recruiting'}]}, 'descriptionModule': {'briefSummary': "The study is designed as a multicenter, randomized, open label Phase 3 study to compare the efficacy and safety of golcadomide in combination with rituximab vs investigator's choice in participants with relapsed/refractory follicular lymphoma who have received at least one line of prior systemic therapy."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Participant has histologically confirmed FL (Grade 1, 2, 3a or classic FL) as assessed by local pathology. Adequate fresh tumor biopsy tissue or archived tumor biopsy from the latest relapse if available with corresponding pathology report for retrospective central pathology confirmation of relapse, is required. Evaluation from fine needle aspirate is not permitted.\n* Relapsed or refractory disease:\n\n 1. Relapsed FL is defined as relapse after an initial response of CR or PR to the most recent prior therapy.\n 2. Refractory FL is defined as best response of SD or PD or a response that lasted less than 6 months to the most recent prior therapy.\n* Eastern Cooperative Oncology Group (ECOG) 0-2 (ECOG 3 authorized if it is due to lymphoma and not comorbidities).\n* Participant must have positron emission tomography (PET)-positive disease with at least one PET-positive lesion and measurable disease on cross section imaging by CT, as defined by Lugano classification.\n* Participants with an indication for anti-lymphoma treatment as per investigator assessment based on modified Groupe d'Etude des Lymphomes Folliculaires (GELF) criteria.\n* Participant has received at least 1 or more prior lines of systemic therapy with one line consisting of a combination including an anti-CD20 monoclonal antibody (eg, rituximab, obinutuzumab) and an alkylating agent (eg, cyclophosphamide, bendamustine). Prior treatment with radiation therapy does not count as a line of therapy for eligibility.\n* Lab parameters:\n\n 1. Absolute neutrophil count (ANC) ≥ 1,000 cells/mm3 (1.0 x 109 /L),\n 2. PLT count ≥ 75,000 cells/mm3 (75 x 109 /L)\n 3. Hb ≥ 7.5 g/dL\n* estimated glomerular filtration rate (eGFR) ≥ 30 ml/min/1.73m².\n* Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) ≤ 2.5 x upper limit of normal (ULN). In case of documented liver involvement by lymphoma, ALT/SGPT and AST/SGOT must be ≤ 5.0× ULN.\n* Serum total bilirubin ≤ 1.5 × ULN (corresponding to mild dysfunction as per National Cancer Institute Organ Dysfunction Working Group \\[NCI ODWG\\] criteria). In case of documented liver involvement by lymphoma, serum total bilirubin must be ≤ 3.0 × ULN (corresponding to moderate dysfunction as per NCI ODWG criteria). For cases of Gilberts syndrome, serum total bilirubin≤ 5.0 × ULN\n* Adequate cardiac function for participants receiving anthracycline-based chemotherapy, defined as left ventricular ejection fraction (LVEF) ≥ 45% as assessed by echocardiogram (ECHO) as standard of care or multi-gated acquisition scan (MUGA)\n\nExclusion Criteria:\n\n* Evidence or history of composite Diffuse large B-cell lymphoma (DLBCL) and FL or of transformed Non-Hodgkin Lymphoma (NHL) or any other indolent lymphoma.\n* Follicular large cell as per 5th World Health Organization (WHO) sub-classification (grade 3b FL per WHO 4th classification) or duodenal-type FL.\n* Participant has any significant medical condition, laboratory abnormality, or psychiatric illness that would prevent the participant from compliantly participating in the study based on Investigator's judgment.\n* Participant has any condition that confounds the ability to interpret data from the study based on Investigator's or Sponsor's judgment.\n* Presence or history of central nervous system (CNS) involvement by lymphoma.\n* History of stroke or intracranial hemorrhage within 6 months prior to enrollment.\n* Deep venous thrombosis/Pulmonary embolism within 1 month prior to enrollment.\n* Participants with a history of progressive multifocal leukoencephalopathy.\n* Participant has any other subtype of lymphoma.\n* Participant has persistent diarrhea or malabsorption ≥ Grade 2 (NCI CTCAE v5.0), despite medical management.\n* History of another primary malignancy that has not been in remission for ≥ 3 years except for non-invasive malignancies.\n* Other protocol-defined Inclusion/Exclusion criteria apply."}, 'identificationModule': {'nctId': 'NCT06911502', 'briefTitle': "A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)", 'organization': {'class': 'INDUSTRY', 'fullName': 'Celgene'}, 'officialTitle': "A Phase 3, Multicenter, Randomized, Open Label Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) Vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy", 'orgStudyIdInfo': {'id': 'CA073-1003'}, 'secondaryIdInfos': [{'id': '2024-519152-82', 'type': 'OTHER', 'domain': 'EU CTR'}, {'id': 'U1111-1314-3909', 'type': 'OTHER', 'domain': 'WHO'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Golcadomide + Rituximab', 'interventionNames': ['Drug: Golcadomide', 'Drug: Rituximab']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Rituximab + Lenalidomide/Chemotherapy', 'description': 'Rituximab + Lenalidomide or R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone/prednisolone) or Rituximab + Bendamustine', 'interventionNames': ['Drug: Rituximab', 'Drug: Lenalidomide', 'Drug: Cyclophosphamide', 'Drug: Doxorubicin', 'Drug: Vincristine', 'Drug: Prednisone/Prednisolone', 'Drug: Bendamustine']}], 'interventions': [{'name': 'Golcadomide', 'type': 'DRUG', 'otherNames': ['CC-99282', 'BMS-986369'], 'description': 'Specified dose on specified days', 'armGroupLabels': ['Golcadomide + Rituximab']}, {'name': 'Rituximab', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Golcadomide + Rituximab', 'Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Lenalidomide', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Cyclophosphamide', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Doxorubicin', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Vincristine', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Prednisone/Prednisolone', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}, {'name': 'Bendamustine', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Rituximab + Lenalidomide/Chemotherapy']}]}, 'contactsLocationsModule': {'locations': [{'zip': '35205', 'city': 'Birmingham', 'state': 'Alabama', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0225', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0225', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '36607', 'city': 'Mobile', 'state': 'Alabama', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Furhan Yunus, Site 0014', 'role': 'CONTACT', 'phone': '901-634-5546'}], 'facility': 'Infirmary Cancer Care', 'geoPoint': {'lat': 30.69436, 'lon': -88.04305}}, {'zip': '99508', 'city': 'Anchorage', 'state': 'Alaska', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Steven Liu, Site 0074', 'role': 'CONTACT', 'phone': '907-257-9851'}], 'facility': 'Alaska Oncology and Hematology', 'geoPoint': {'lat': 61.21806, 'lon': -149.90028}}, {'zip': '72205', 'city': 'Little Rock', 'state': 'Arkansas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0215', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0215', 'geoPoint': {'lat': 34.74648, 'lon': -92.28959}}, {'zip': '91010', 'city': 'Duarte', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Alex Herrera, Site 0072', 'role': 'CONTACT', 'phone': '626-218-2405'}], 'facility': 'City of Hope Comprehensive Cancer Center', 'geoPoint': {'lat': 34.13945, 'lon': -117.97729}}, {'zip': '94143', 'city': 'San Francisco', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Charalambos Andreadis, Site 0119', 'role': 'CONTACT', 'phone': '415-238-1909'}], 'facility': 'UCSF Helen Diller Medical Center at Parnassus Heights', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}, {'zip': '32256', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0008', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0008', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '33606', 'city': 'Tampa', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0214', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0214', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '33612', 'city': 'Tampa', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0217', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0217', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '30060', 'city': 'Marietta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Dean Kirkel, Site 0021', 'role': 'CONTACT', 'phone': '770-281-5100'}], 'facility': 'Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital', 'geoPoint': {'lat': 33.9526, 'lon': -84.54993}}, {'zip': '30265', 'city': 'Newnan', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Sabarish Ayyappan, Site 0245', 'role': 'CONTACT', 'phone': '000-000-0000'}], 'facility': 'Southeastern Regional Medical Center', 'geoPoint': {'lat': 33.38067, 'lon': -84.79966}}, {'zip': '60005', 'city': 'Arlington Heights', 'state': 'Illinois', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0240', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0240', 'geoPoint': {'lat': 42.08836, 'lon': -87.98063}}, {'zip': '52242', 'city': 'Iowa City', 'state': 'Iowa', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0253', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0253', 'geoPoint': {'lat': 41.66113, 'lon': -91.53017}}, {'zip': '50309', 'city': 'Waukee', 'state': 'Iowa', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0243', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0243', 'geoPoint': {'lat': 41.61166, 'lon': -93.88523}}, {'zip': '66205', 'city': 'Westwood', 'state': 'Kansas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0216', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0216', 'geoPoint': {'lat': 39.04056, 'lon': -94.6169}}, {'zip': '40536', 'city': 'Lexington', 'state': 'Kentucky', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0218', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0218', 'geoPoint': {'lat': 37.98869, 'lon': -84.47772}}, {'zip': '21201', 'city': 'Baltimore', 'state': 'Maryland', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0023', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0023', 'geoPoint': {'lat': 39.29038, 'lon': -76.61219}}, {'zip': '21204', 'city': 'Towson', 'state': 'Maryland', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Zhuoyan Li, Site 0010', 'role': 'CONTACT', 'phone': '443-849-3051'}], 'facility': 'Greater Baltimore Medical Center', 'geoPoint': {'lat': 39.4015, 'lon': -76.60191}}, {'zip': '02114', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0145', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0145', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0244', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0244', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0247', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0247', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '39401-7233', 'city': 'Hattiesburg', 'state': 'Mississippi', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'John Hrom, Site 0013', 'role': 'CONTACT', 'phone': '601-261-1700'}], 'facility': 'Hattiesburg Clinic Hematology/Oncology', 'geoPoint': {'lat': 31.32712, 'lon': -89.29034}}, {'zip': '02903', 'city': 'Providence', 'state': 'Rhode Island', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0144', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0144', 'geoPoint': {'lat': 41.82399, 'lon': -71.41283}}, {'zip': '78705', 'city': 'Austin', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jason Melear, Site 0237', 'role': 'CONTACT', 'phone': '512-427-9400'}], 'facility': 'Texas Oncology - 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