Ignite Creation Date:
2025-12-25 @ 3:44 AM
Ignite Modification Date:
2025-12-26 @ 2:30 AM
Study NCT ID:
NCT00995202
Status:
COMPLETED
Last Update Posted:
2021-12-07
First Post:
2009-10-14
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D015179', 'term': 'Colorectal Neoplasms'}, {'id': 'D003110', 'term': 'Colonic Neoplasms'}, {'id': 'D012004', 'term': 'Rectal Neoplasms'}], 'ancestors': [{'id': 'D007414', 'term': 'Intestinal Neoplasms'}, {'id': 'D005770', 'term': 'Gastrointestinal Neoplasms'}, {'id': 'D004067', 'term': 'Digestive System Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D004066', 'term': 'Digestive System Diseases'}, {'id': 'D005767', 'term': 'Gastrointestinal Diseases'}, {'id': 'D003108', 'term': 'Colonic Diseases'}, {'id': 'D007410', 'term': 'Intestinal Diseases'}, {'id': 'D012002', 'term': 'Rectal Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'PREVENTION', 'interventionModel': 'FACTORIAL', 'interventionModelDescription': 'This study is a surveillance study not an interventional study with products'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 1997}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2009-09', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-12', 'completionDateStruct': {'date': '2021-06', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-12-06', 'studyFirstSubmitDate': '2009-10-14', 'studyFirstSubmitQcDate': '2009-10-14', 'lastUpdatePostDateStruct': {'date': '2021-12-07', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2009-10-15', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2019-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Overall survival rate', 'timeFrame': '5 years', 'description': 'Time between randomization and date of death (all causes)'}], 'secondaryOutcomes': [{'measure': 'Disease-free survival rate', 'timeFrame': '5 years', 'description': 'Time between randomization and first recurrence (local or metastatic) or death (all causes)'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['stage II colon cancer', 'stage II rectal cancer', 'stage III colon cancer', 'stage III rectal cancer', 'adenocarcinoma of the colon', 'adenocarcinoma of the rectum'], 'conditions': ['Colorectal Cancer']}, 'referencesModule': {'references': [{'pmid': '25933809', 'type': 'BACKGROUND', 'citation': 'Lepage C, Phelip JM, Cany L, Faroux R, Manfredi S, Ain JF, Pezet D, Baconnier M, Deguiral P, Terrebone E, Adenis A, Le Malicot K, Bedenne L, Bouche O. Effect of 5 years of imaging and CEA follow-up to detect recurrence of colorectal cancer: The FFCD PRODIGE 13 randomised phase III trial. Dig Liver Dis. 2015 Jul;47(7):529-31. doi: 10.1016/j.dld.2015.03.021. Epub 2015 Apr 2. No abstract available.'}]}, 'descriptionModule': {'briefSummary': "RATIONALE: Diagnostic procedures, such as ultrasound, x-ray, colonoscopy, CT scan, and CEA assessment, may help monitor a patient's response to surgery. It is not yet known which follow-up regimen is more effective in patients who have undergone surgery for colorectal cancer.\n\nPURPOSE: This randomized phase III trial is comparing two types of follow-up care with or without CEA assessments to see how well they work in patients who have undergone surgery for stage II or stage III colorectal cancer.", 'detailedDescription': 'OBJECTIVES:\n\n* Evaluate the efficacy of reinforced versus standard follow-up care and the utility of follow-up CEA assessments in patients with fully resected stage II or III colorectal cancer.\n\nOUTLINE: This is a multinational/multicenter study. Patients are randomized to 1 of 2 follow-up arms.\n\n* Standard follow-up: Patients undergo clinical assessments every 3 months until year 3 and every 6 months until year 5. They are then assessed at least yearly thereafter. Patients undergo abdominal ultrasound every 3 months until year 3 and then every 6 months until year 5; chest x-ray every 6 months until year 3 and then annually until year 5; and colonoscopy at 3 years after surgery then every 3 to 6 years thereafter.\n* Reinforced follow-up: Patients undergo clinical assessments every 3 months until year 3 and every 6 months until year 5. They are then assessed at least yearly thereafter. Patients undergo alternate assessments every 3 months comprising thoraco-abdomino-pelvic CT scan or abdominal ultrasound until year 3 and then every 6 months until year 5. They also undergo colonoscopy at 3 years after surgery then every 3 to 6 years thereafter.\n\nPatients undergo a second randomization to 1 of 2 follow-up arms at the beginning of the study.\n\n* CEA measurement: Patients undergo measurement of CEA levels every 3 months until year 3, every 6 months until year 5, and at least yearly thereafter.\n* No CEA measurement: Patients do not undergo CEA measurement. Blood and tissue blocks of normal and tumor tissues are collected for the validation of protein serum, genetics, or immunologic markers predictive for relapse.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '120 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'DISEASE CHARACTERISTICS:\n\n* Pathologically confirmed adenocarcinoma of the colon or rectum\n\n * Stage II or III disease\n * No distant metastatic disease\n* Has undergone curative resection for no residual tumor\n* Carcinoembryonic antigen (CEA) ≤ 1.5 x upper limit of normal after surgery\n\nPATIENT CHARACTERISTICS:\n\n* WHO performance status 0-1\n* Not pregnant or nursing\n* Fertile patients must use effective contraception\n* No inflammatory bowel disease\n* No other malignancy within the past 5 years except basal cell carcinoma of the skin and/or carcinoma in situ of the cervix\n* No genetic syndromes\n\nPRIOR CONCURRENT THERAPY:\n\n* See Disease Characteristics'}, 'identificationModule': {'nctId': 'NCT00995202', 'acronym': 'SURVEILLANCE', 'briefTitle': 'Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer', 'organization': {'class': 'OTHER', 'fullName': 'Federation Francophone de Cancerologie Digestive'}, 'officialTitle': 'Follow-Up of Fully Resected Stage II or III Colorectal Cancer. Phase III Multicentric Prospective Randomised Study', 'orgStudyIdInfo': {'id': 'PRODIGE 13'}, 'secondaryIdInfos': [{'id': 'FFCD-PRODIGE-13'}, {'id': '2009-A00536-51'}, {'id': 'EU-20979'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'OTHER', 'label': 'Standard Monitoring CEA/ Standard Imagery', 'description': 'No specific follow-up of CEA and Standard imagery', 'interventionNames': ['Procedure: Standard Monitoring CEA', 'Procedure: Standard Monitoring Imagery']}, {'type': 'OTHER', 'label': 'Intensive monitoring CEA/ Standard Imagery', 'description': 'Intensive follow-up CEA and Standard imagery .', 'interventionNames': ['Procedure: Intensive Monitoring CEA', 'Procedure: Standard Monitoring Imagery']}, {'type': 'OTHER', 'label': 'Intensive Monitoring CEA / Intensive Monitoring Imagery', 'description': 'Intensive follow-up CEA and Intensive imagery', 'interventionNames': ['Procedure: Intensive Monitoring CEA', 'Procedure: Intensive Monitoring Imagery']}, {'type': 'OTHER', 'label': 'Standard Monitoring CEA/ Intensive Monitoring Imagery', 'description': 'No specific follow-up of CEA and Intensive Imagery', 'interventionNames': ['Procedure: Standard Monitoring CEA', 'Procedure: Intensive Monitoring Imagery']}], 'interventions': [{'name': 'Standard Monitoring CEA', 'type': 'PROCEDURE', 'description': 'No specific follow-up of CEA', 'armGroupLabels': ['Standard Monitoring CEA/ Intensive Monitoring Imagery', 'Standard Monitoring CEA/ Standard Imagery']}, {'name': 'Intensive Monitoring CEA', 'type': 'PROCEDURE', 'description': 'CEA levels are measured every 3 months for 3 years, then every 6 months for 2 years.', 'armGroupLabels': ['Intensive Monitoring CEA / Intensive Monitoring Imagery', 'Intensive monitoring CEA/ Standard Imagery']}, {'name': 'Standard Monitoring Imagery', 'type': 'PROCEDURE', 'description': 'Abdominal ultrasound examination every 3 months during 3 years then every 6 months during 2 years then annually. Chest X-ray examination eveyr 6 months during 3 years then annually during 2 years', 'armGroupLabels': ['Intensive monitoring CEA/ Standard Imagery', 'Standard Monitoring CEA/ Standard Imagery']}, {'name': 'Intensive Monitoring Imagery', 'type': 'PROCEDURE', 'description': 'Alternation every 3 months of TDM thoraco-abdomino-pelvis and abdominal ultrasound examination during 3 years and twice a year after during 2 years. Coloscopy at 3 years and then evry 5 years if normal', 'armGroupLabels': ['Intensive Monitoring CEA / Intensive Monitoring Imagery', 'Standard Monitoring CEA/ Intensive Monitoring Imagery']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Arlon', 'country': 'Belgium', 'facility': 'Clinique Sud Luxembourg', 'geoPoint': {'lat': 49.68333, 'lon': 5.81667}}, {'city': 'Abbeville', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 50.10521, 'lon': 1.83547}}, {'city': 'Abbeville', 'country': 'France', 'facility': 'Clinique Isabelle', 'geoPoint': {'lat': 50.10521, 'lon': 1.83547}}, {'city': 'Amiens', 'country': 'France', 'facility': 'CHU Nord', 'geoPoint': {'lat': 49.9, 'lon': 2.3}}, {'city': 'Angers', 'country': 'France', 'facility': 'CHU', 'geoPoint': {'lat': 47.47156, 'lon': -0.55202}}, {'city': 'Antibes', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.58127, 'lon': 7.12487}}, {'city': 'Aubenas', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 44.61975, 'lon': 4.39033}}, {'city': 'Auch', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.64561, 'lon': 0.58856}}, {'city': 'Auxerre', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.7996, 'lon': 3.57033}}, {'city': 'Auxerre', 'country': 'France', 'facility': 'Polyclinique Ste Marguerite', 'geoPoint': {'lat': 47.7996, 'lon': 3.57033}}, {'city': 'Avignon', 'country': 'France', 'facility': 'CH Henri Duffaut', 'geoPoint': {'lat': 43.94834, 'lon': 4.80892}}, {'city': 'Avignon', 'country': 'France', 'facility': 'Clinique Sainte Cahterine', 'geoPoint': {'lat': 43.94834, 'lon': 4.80892}}, {'city': 'Bayonne', 'country': 'France', 'facility': "Centre d'oncologie et de radiothérapie du Pays Basque", 'geoPoint': {'lat': 43.49316, 'lon': -1.473}}, {'city': 'Beaune', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.02413, 'lon': 4.83887}}, {'city': 'Beauvais', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.43333, 'lon': 2.08333}}, {'city': 'Besançon', 'country': 'France', 'facility': 'CHU J Minjoz', 'geoPoint': {'lat': 47.24878, 'lon': 6.01815}}, {'city': 'Béziers', 'country': 'France', 'facility': "Centre de Radiothérapie et d'oncologie médicale", 'geoPoint': {'lat': 43.34122, 'lon': 3.21402}}, {'city': 'Béziers', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.34122, 'lon': 3.21402}}, {'city': 'Blois', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.59432, 'lon': 1.32912}}, {'city': 'Bobigny', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.90982, 'lon': 2.45012}}, {'city': 'Bordeaux', 'country': 'France', 'facility': 'Polyclinique Nord Aquitaine', 'geoPoint': {'lat': 44.84124, 'lon': -0.58046}}, {'city': 'Boulogne-sur-Mer', 'country': 'France', 'facility': 'CH Duchenne', 'geoPoint': {'lat': 50.72485, 'lon': 1.61373}}, {'city': 'Bourg-en-Bresse', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 46.20574, 'lon': 5.2258}}, {'city': 'Brest', 'country': 'France', 'facility': 'Hôpital du Morvan', 'geoPoint': {'lat': 48.39029, 'lon': -4.48628}}, {'city': 'Briey', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.2492, 'lon': 5.93975}}, {'city': 'Castres', 'country': 'France', 'facility': 'CHIC', 'geoPoint': {'lat': 43.60527, 'lon': 2.24088}}, {'city': 'Challans', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 46.8458, 'lon': -1.87942}}, {'city': 'Chalon-sur-Saône', 'country': 'France', 'facility': 'Hôpital Sainte Marie', 'geoPoint': {'lat': 46.78112, 'lon': 4.85372}}, {'city': 'Chambéry', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 45.56628, 'lon': 5.92079}}, {'city': 'Chambéry', 'country': 'France', 'facility': 'Clinique du Cléret et Clinique Saint Joseph', 'geoPoint': {'lat': 45.56628, 'lon': 5.92079}}, {'city': 'Châlons-en-Champagne', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.95393, 'lon': 4.36724}}, {'city': 'Cholet', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.05893, 'lon': -0.87974}}, {'city': 'Clermont-Ferrand', 'country': 'France', 'facility': 'CHU Estaing', 'geoPoint': {'lat': 45.77969, 'lon': 3.08682}}, {'city': 'Colmar', 'country': 'France', 'facility': 'Hôpital Pästeur', 'geoPoint': {'lat': 48.08078, 'lon': 7.35584}}, {'city': 'Compiègne', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.41794, 'lon': 2.82606}}, {'city': 'Coquelles', 'country': 'France', 'facility': 'Clinique des 2 Caps', 'geoPoint': {'lat': 50.93461, 'lon': 1.7988}}, {'city': 'Cornebarrieu', 'country': 'France', 'facility': 'Clinique des Cèdres', 'geoPoint': {'lat': 43.64967, 'lon': 1.32588}}, {'city': 'Cucq', 'country': 'France', 'facility': 'Clinique des Acacias', 'geoPoint': {'lat': 50.47733, 'lon': 1.62018}}, {'city': 'Dax', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.71032, 'lon': -1.05366}}, {'city': 'Dijon', 'country': 'France', 'facility': "Cabinet d'HGE - Cours De Gaulle", 'geoPoint': {'lat': 47.31344, 'lon': 5.01391}}, {'city': 'Dijon', 'country': 'France', 'facility': 'Cabinet Privé Point Médical', 'geoPoint': {'lat': 47.31344, 'lon': 5.01391}}, {'city': 'Dijon', 'country': 'France', 'facility': "Centre d'Oncologie Médicale du Parc", 'geoPoint': {'lat': 47.31344, 'lon': 5.01391}}, {'city': 'Dijon', 'country': 'France', 'facility': 'CHU le bocage', 'geoPoint': {'lat': 47.31344, 'lon': 5.01391}}, {'city': 'Draguignan', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.53692, 'lon': 6.46458}}, {'city': 'Épernay', 'country': 'France', 'facility': 'Clinique Saint Vincent', 'geoPoint': {'lat': 49.04, 'lon': 3.95922}}, {'city': 'Férolles-Attilly', 'country': 'France', 'facility': 'Centre médical de Forcilles', 'geoPoint': {'lat': 48.73184, 'lon': 2.63088}}, {'city': 'Fréjus', 'country': 'France', 'facility': 'CHI Saint Raphael', 'geoPoint': {'lat': 43.43325, 'lon': 6.73555}}, {'city': 'Gap', 'country': 'France', 'facility': 'CHI', 'geoPoint': {'lat': 44.55858, 'lon': 6.07868}}, {'city': 'Grenoble', 'country': 'France', 'facility': 'Institut Hollard', 'geoPoint': {'lat': 45.17869, 'lon': 5.71479}}, {'city': 'Haguenau', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.81557, 'lon': 7.79051}}, {'city': 'La Roche-sur-Yon', 'country': 'France', 'facility': 'CHD', 'geoPoint': {'lat': 46.66974, 'lon': -1.42757}}, {'city': 'Lagny-sur-Marne', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.86667, 'lon': 2.71667}}, {'city': 'Le Coudray', 'country': 'France', 'facility': 'CH Louis Pasteur', 'geoPoint': {'lat': 48.42115, 'lon': 1.50057}}, {'city': 'Le Havre', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.49346, 'lon': 0.10785}}, {'city': 'Le Mans', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.0021, 'lon': 0.20251}}, {'city': 'Libourne', 'country': 'France', 'facility': 'Hôpital Robert Boulin', 'geoPoint': {'lat': 44.91449, 'lon': -0.24186}}, {'city': 'Lille', 'country': 'France', 'facility': 'Centre Oscar Lambret', 'geoPoint': {'lat': 50.63391, 'lon': 3.05512}}, {'city': 'Longjumeau', 'country': 'France', 'facility': 'CHG', 'geoPoint': {'lat': 48.69307, 'lon': 2.29431}}, {'city': 'Lormont', 'country': 'France', 'facility': 'Clinique des 4 pavillons', 'geoPoint': {'lat': 44.8765, 'lon': -0.51919}}, {'city': 'Lyon', 'country': 'France', 'facility': 'CHU Lyon Sud', 'geoPoint': {'lat': 45.74906, 'lon': 4.84789}}, {'city': 'Marseille', 'country': 'France', 'facility': 'CH Saint Joseph', 'geoPoint': {'lat': 43.29695, 'lon': 5.38107}}, {'city': 'Marseille', 'country': 'France', 'facility': 'CHU La Timone', 'geoPoint': {'lat': 43.29695, 'lon': 5.38107}}, {'city': 'Marseille', 'country': 'France', 'facility': 'Hôpital Européen', 'geoPoint': {'lat': 43.29695, 'lon': 5.38107}}, {'city': 'Marseille', 'country': 'France', 'facility': 'Hôpital Nord', 'geoPoint': {'lat': 43.29695, 'lon': 5.38107}}, {'city': 'Mâcon', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 46.31407, 'lon': 4.82823}}, {'city': 'Mâcon', 'country': 'France', 'facility': 'Polyclinique du Val de Saône', 'geoPoint': {'lat': 46.31407, 'lon': 4.82823}}, {'city': 'Mont-de-Marsan', 'country': 'France', 'facility': 'Hôpital Layné', 'geoPoint': {'lat': 43.89022, 'lon': -0.49713}}, {'city': 'Montbrison', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 45.60752, 'lon': 4.06525}}, {'city': 'Montceau-les-Mines', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 46.66667, 'lon': 4.36667}}, {'city': 'Montélimar', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 44.55468, 'lon': 4.75469}}, {'city': 'Montfermeil', 'country': 'France', 'facility': 'CHI Le Raincy Montfermeil', 'geoPoint': {'lat': 48.8982, 'lon': 2.57913}}, {'city': 'Mougins', 'country': 'France', 'facility': 'Centre Azuréen de Cancérologie', 'geoPoint': {'lat': 43.60068, 'lon': 6.99523}}, {'city': 'Neuilly-sur-Seine', 'country': 'France', 'facility': 'Hopital Americain de Paris', 'geoPoint': {'lat': 48.8846, 'lon': 2.26965}}, {'city': 'Nevers', 'country': 'France', 'facility': 'Polyclinique Val de Loire', 'geoPoint': {'lat': 46.98956, 'lon': 3.159}}, {'city': 'Nice', 'country': 'France', 'facility': "Hôpital l'Archet II", 'geoPoint': {'lat': 43.70313, 'lon': 7.26608}}, {'city': 'Nîmes', 'country': 'France', 'facility': 'CHU Carémeau', 'geoPoint': {'lat': 43.83665, 'lon': 4.35788}}, {'city': 'Nîmes', 'country': 'France', 'facility': 'Clinique Valdegour', 'geoPoint': {'lat': 43.83665, 'lon': 4.35788}}, {'city': 'Orléans', 'country': 'France', 'facility': "CHR - Sce D'HGE", 'geoPoint': {'lat': 47.90248, 'lon': 1.90407}}, {'city': 'Orléans', 'country': 'France', 'facility': "CHR - Sce d'Oncologie", 'geoPoint': {'lat': 47.90248, 'lon': 1.90407}}, {'city': 'Paris', 'country': 'France', 'facility': 'Hôpital Privé Les Peupliers', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}, {'city': 'Paris', 'country': 'France', 'facility': 'Hôpital Saint Louis', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}, {'city': 'Pau', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 43.31117, 'lon': -0.35583}}, {'city': 'Perpignan', 'country': 'France', 'facility': "Centre Catalan d'Oncologie", 'geoPoint': {'lat': 42.69764, 'lon': 2.89541}}, {'city': 'Perpignan', 'country': 'France', 'facility': 'Hôpital Saint Jean', 'geoPoint': {'lat': 42.69764, 'lon': 2.89541}}, {'city': 'Pessac', 'country': 'France', 'facility': 'CHU Haut Lévèque', 'geoPoint': {'lat': 44.80565, 'lon': -0.6324}}, {'city': 'Périgueux', 'country': 'France', 'facility': 'Polyclinique Francheville', 'geoPoint': {'lat': 45.18691, 'lon': 0.71439}}, {'city': 'Pringy', 'country': 'France', 'facility': 'Centre Hospitalier Annecy Genevois', 'geoPoint': {'lat': 45.94622, 'lon': 6.12608}}, {'city': 'Privas', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 44.735, 'lon': 4.59918}}, {'city': 'Reims', 'country': 'France', 'facility': 'CHU Robert Debré', 'geoPoint': {'lat': 49.26526, 'lon': 4.02853}}, {'city': 'Reims', 'country': 'France', 'facility': 'Institut Jean Godinot', 'geoPoint': {'lat': 49.26526, 'lon': 4.02853}}, {'city': 'Rennes', 'country': 'France', 'facility': 'CHU Pontchaillou', 'geoPoint': {'lat': 48.11109, 'lon': -1.67431}}, {'city': 'Rodez', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 44.35258, 'lon': 2.57338}}, {'city': 'Romans-sur-Isère', 'country': 'France', 'facility': 'CH Romans', 'geoPoint': {'lat': 45.0496, 'lon': 5.06602}}, {'city': 'Saint-Brieuc', 'country': 'France', 'facility': 'CH Yves Lefoll', 'geoPoint': {'lat': 48.51513, 'lon': -2.76838}}, {'city': 'Saint-Chamond', 'country': 'France', 'facility': 'CHPG', 'geoPoint': {'lat': 45.4759, 'lon': 4.51294}}, {'city': 'Saint-Dié', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.28429, 'lon': 6.94921}}, {'city': 'Saint-Etienne', 'country': 'France', 'facility': 'CHU', 'geoPoint': {'lat': 45.43389, 'lon': 4.39}}, {'city': 'Saint-Jean-de-Luz', 'country': 'France', 'facility': 'Polyclinique Côte Basque Sud', 'geoPoint': {'lat': 43.38871, 'lon': -1.66267}}, {'city': 'Saint-Martin-Boulogne', 'country': 'France', 'facility': 'Centre Joliot Curie', 'geoPoint': {'lat': 50.72691, 'lon': 1.61864}}, {'city': 'Saint-Martin-Boulogne', 'country': 'France', 'facility': "Clinique de la Côte d'Opale", 'geoPoint': {'lat': 50.72691, 'lon': 1.61864}}, {'city': 'Saint-Nazaire', 'country': 'France', 'facility': "Clinique Mutualiste de l'Estuaire - Cité Sanitaire", 'geoPoint': {'lat': 47.27506, 'lon': -2.2179}}, {'city': 'Sainte-Colombe', 'country': 'France', 'facility': 'Clinique', 'geoPoint': {'lat': 45.52531, 'lon': 4.86664}}, {'city': 'Sainte-Feyre', 'country': 'France', 'facility': 'Centre Médical National MGEN Alfred Leune', 'geoPoint': {'lat': 46.13904, 'lon': 1.91525}}, {'city': 'Semur-en-Auxois', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.48333, 'lon': 4.33333}}, {'city': 'Soissons', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.38167, 'lon': 3.32361}}, {'city': 'St-Malo', 'country': 'France', 'facility': 'Hôpital Broussais', 'geoPoint': {'lat': 48.64738, 'lon': -2.00877}}, {'city': 'Strasbourg', 'country': 'France', 'facility': 'Centre Paul Strauss', 'geoPoint': {'lat': 48.58392, 'lon': 7.74553}}, {'city': 'Toulon', 'country': 'France', 'facility': 'Hôpital Sainte Musse', 'geoPoint': {'lat': 43.12442, 'lon': 5.92836}}, {'city': 'Tourcoing', 'country': 'France', 'facility': 'CH Gustave Dron', 'geoPoint': {'lat': 50.72391, 'lon': 3.16117}}, {'city': 'Tours', 'country': 'France', 'facility': 'CH Trousseau', 'geoPoint': {'lat': 47.39484, 'lon': 0.70398}}, {'city': 'Valence', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 44.9256, 'lon': 4.90956}}, {'city': 'Vannes', 'country': 'France', 'facility': 'CHBA', 'geoPoint': {'lat': 47.65688, 'lon': -2.76205}}, {'city': 'Vernon', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 49.09292, 'lon': 1.46332}}, {'city': 'Vesoul', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 47.62604, 'lon': 6.14251}}, {'city': "Villeneuve-d'Ascq", 'country': 'France', 'facility': 'CH Privé', 'geoPoint': {'lat': 50.61669, 'lon': 3.16664}}, {'city': 'Villeneuve-Saint-Georges', 'country': 'France', 'facility': 'CH', 'geoPoint': {'lat': 48.73219, 'lon': 2.44925}}, {'city': 'Fort-de-France', 'country': 'Martinique', 'facility': 'CHU Clarac', 'geoPoint': {'lat': 14.60365, 'lon': -61.07418}}], 'overallOfficials': [{'name': 'Come Lepage, Pr', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Centre Hospitalier Universitaire Dijon'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Federation Francophone de Cancerologie Digestive', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}