Ignite Creation Date:
2025-12-25 @ 3:38 AM
Ignite Modification Date:
2025-12-26 @ 2:21 AM
Study NCT ID:
NCT05348902
Status:
UNKNOWN
Last Update Posted:
2022-04-27
First Post:
2022-04-10
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2021-10-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-10', 'completionDateStruct': {'date': '2022-06-02', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2022-04-26', 'studyFirstSubmitDate': '2022-04-10', 'studyFirstSubmitQcDate': '2022-04-26', 'lastUpdatePostDateStruct': {'date': '2022-04-27', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2022-04-27', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2022-06-02', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Locked-in syndrome caused by pulmonary arteriovenous malformation . Check list report', 'timeFrame': '1month', 'description': 'A recommendation is made for the treatment and prognosis of patients with severe atresia caused by arteriovenous fistula.'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Locked-In Syndrome；Pulmonary Arteriovenous Malformation']}, 'descriptionModule': {'briefSummary': 'In this case, we report a case of atresia syndrome (LIS), a serious neurological disease caused by pulmonary arteriovenous fistula (PAVM). We present a previously healthy middle-aged woman who developed atresia syndrome after severe pontine infarction due to basilar artery occlusion due to undiagnosed arteriovenous malformation. This report reviewed the medical history, post-admission examination and related literature, and concluded that PAVM should be considered as the cause of implicit stroke, especially in young patients with right-to-left shunt, and should be actively treated.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'A patient with locked-in syndrome', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* A case of Locked-in syndrome due to pulmonary arteriovenous malformation\n\nExclusion Criteria:\n\n* Patients or family members objected to the study'}, 'identificationModule': {'nctId': 'NCT05348902', 'briefTitle': 'Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report', 'organization': {'class': 'OTHER', 'fullName': 'Second Affiliated Hospital, School of Medicine, Zhejiang University'}, 'officialTitle': 'Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report', 'orgStudyIdInfo': {'id': '2022-0138'}}, 'armsInterventionsModule': {'interventions': [{'name': 'In this study, only cases were collected and reported without any intervention or adverse reactions', 'type': 'OTHER', 'description': 'In this study, only cases were collected and reported without any intervention or adverse reactions'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Hangzhou', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'hao wang, master', 'role': 'CONTACT', 'email': '2519160@zju.edu.cn', 'phone': '+86 15968891667'}, {'name': 'le zhang, master', 'role': 'CONTACT', 'email': '2319053@zju.edu.cn', 'phone': '+86 13616511229'}], 'facility': '2nd Affiliated Hospital, School of Medicine, Zhejiang University, China', 'geoPoint': {'lat': 30.29365, 'lon': 120.16142}}], 'centralContacts': [{'name': 'hao wang, master', 'role': 'CONTACT', 'email': '2519160@zju.edu.cn', 'phone': '+8615968891667'}, {'name': 'le zhang, master', 'role': 'CONTACT', 'email': '2319053@zju.edu.cn', 'phone': '+8613616511229'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Second Affiliated Hospital, School of Medicine, Zhejiang University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}