Ignite Creation Date:
2025-12-25 @ 3:01 AM
Ignite Modification Date:
2026-02-25 @ 10:05 PM
Study NCT ID:
NCT00867633
Status:
UNKNOWN
Last Update Posted:
2012-02-22
First Post:
2009-03-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Aristolochic Acid-DNA Adduct in Urothelial Carcinoma in Taiwan
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D002295', 'term': 'Carcinoma, Transitional Cell'}], 'ancestors': [{'id': 'D002277', 'term': 'Carcinoma'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'DNA extracted from the resected tissue samples'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 100}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2009-03'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2012-02', 'completionDateStruct': {'date': '2012-03', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2012-02-20', 'studyFirstSubmitDate': '2009-03-22', 'studyFirstSubmitQcDate': '2009-03-22', 'lastUpdatePostDateStruct': {'date': '2012-02-22', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2009-03-24', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'the incidence of aristolochic-acid DNA adduct in the samples', 'timeFrame': 'one week'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['urothelial carinoma', 'aristolochic acid', 'DNA', 'adduct'], 'conditions': ['Urothelial Carcinoma']}, 'descriptionModule': {'briefSummary': 'To study the association between aristolochic acid and urothelial carcinoma in Taiwan'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'The patients who received nephrectomies', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* the resected kidney tissue in the tissue bank\n\nExclusion Criteria:\n\n* the patients who had been ever exposed to arsenics, rubber, chemicals, irradiation for pelvis, or received chemotherapy.'}, 'identificationModule': {'nctId': 'NCT00867633', 'briefTitle': 'Aristolochic Acid-DNA Adduct in Urothelial Carcinoma in Taiwan', 'organization': {'class': 'OTHER', 'fullName': 'National Taiwan University Hospital'}, 'officialTitle': 'Observational Study of Aristolochic Acid-DNA Adduct in Urothelial Carcinoma in Taiwan', 'orgStudyIdInfo': {'id': '200804011R'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Urothelial carcinoma', 'description': 'The DNA samples extracted from the urothelial carcinoma tissue'}, {'label': 'RCC', 'description': 'the DNA sample extracted from RCC'}, {'label': 'Non-cancer', 'description': 'The DNA sample extracted from the non-cancerous kidney tissue'}]}, 'contactsLocationsModule': {'locations': [{'zip': '100', 'city': 'Taipei', 'status': 'RECRUITING', 'country': 'Taiwan', 'contacts': [{'name': 'Yeong-Shiau Pu, Ph.D.', 'role': 'CONTACT', 'email': 'yspu@ntu.edu.tw', 'phone': '886-2-23123456', 'phoneExt': '65249'}], 'facility': 'National Taiwan University Hospital', 'geoPoint': {'lat': 25.05306, 'lon': 121.52639}}], 'centralContacts': [{'name': 'Yeong-Shiau Pu, Ph.D.', 'role': 'CONTACT', 'email': 'yspu@ntu.edu.tw', 'phone': '886-2-23123456', 'phoneExt': '65249'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'National Taiwan University Hospital', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'National Taiwan University Hospital', 'investigatorFullName': 'National Taiwan University Hospital', 'investigatorAffiliation': 'National Taiwan University Hospital'}}}}