Ignite Creation Date:
2025-12-25 @ 2:41 AM
Ignite Modification Date:
2025-12-26 @ 1:20 AM
Study NCT ID:
NCT04450433
Status:
UNKNOWN
Last Update Posted:
2020-06-29
First Post:
2020-06-24
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Functional Study of Metabolites in Patients With Aortic Dissection
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000784', 'term': 'Aortic Dissection'}], 'ancestors': [{'id': 'D000094665', 'term': 'Dissection, Blood Vessel'}, {'id': 'D000783', 'term': 'Aneurysm'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D000094683', 'term': 'Acute Aortic Syndrome'}, {'id': 'D001018', 'term': 'Aortic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2019-11-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2020-06', 'completionDateStruct': {'date': '2020-10-30', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2020-06-24', 'studyFirstSubmitDate': '2020-06-24', 'studyFirstSubmitQcDate': '2020-06-24', 'lastUpdatePostDateStruct': {'date': '2020-06-29', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2020-06-29', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2020-07-30', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Differential expression of metabolites in two groups of patients', 'timeFrame': '2019-11----2021.01', 'description': 'Differential expression of metabolites in the two groups of patients, looking for metabolic factors related to the incidence of aortic dissection, and further verifying the function of metabolites through functional methods, with a view to finding high-risk metabolic factors for patients with aortic dissection'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Aortic Dissection']}, 'descriptionModule': {'briefSummary': 'Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional verification The role of formation, and ultimately explore the early screening of potential aortic dissection patients'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '30 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': '30 patients with aortic dissection and 15 healthy people', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* patients with Aortic dissection\n\nExclusion Criteria:\n\n* Sepsis'}, 'identificationModule': {'nctId': 'NCT04450433', 'briefTitle': 'Functional Study of Metabolites in Patients With Aortic Dissection', 'organization': {'class': 'OTHER', 'fullName': "Shenzhen People's Hospital"}, 'officialTitle': 'Functional Study of Metabolites in Patients With Aortic Dissection', 'orgStudyIdInfo': {'id': "Liuhuadong's Research Group"}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Baseline table of patients', 'interventionNames': ['Diagnostic Test: aortic dissection and healthy people']}, {'label': 'Differential metabolites of two groups of control patients', 'interventionNames': ['Diagnostic Test: aortic dissection and healthy people']}, {'label': 'Functional verification of differential metabolites', 'interventionNames': ['Diagnostic Test: aortic dissection and healthy people']}], 'interventions': [{'name': 'aortic dissection and healthy people', 'type': 'DIAGNOSTIC_TEST', 'description': 'Differential expression of metabolites in patients with aortic dissection and healthy people', 'armGroupLabels': ['Baseline table of patients', 'Differential metabolites of two groups of control patients', 'Functional verification of differential metabolites']}]}, 'contactsLocationsModule': {'locations': [{'zip': '518020', 'city': 'Shenzhen', 'state': 'Guangdong', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Huadong Liu, PhD', 'role': 'CONTACT', 'email': 'lhd2578@163.com', 'phone': '13724397998'}], 'facility': "Shenzhen People's Hospital", 'geoPoint': {'lat': 22.54554, 'lon': 114.0683}}], 'centralContacts': [{'name': 'Huadong Liu', 'role': 'CONTACT', 'email': 'lhd2578@163.com', 'phone': '13724397998'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'UNDECIDED'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': "Shenzhen People's Hospital", 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}