Ignite Creation Date:
2025-12-24 @ 2:28 PM
Ignite Modification Date:
2026-01-05 @ 12:27 PM
Study NCT ID:
NCT03089359
Status:
COMPLETED
Last Update Posted:
2021-03-25
First Post:
2017-03-20
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Prehospital Recognition and Identification of Unspecific Symptoms
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 414}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-05-04', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-03', 'completionDateStruct': {'date': '2021-03-23', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-03-24', 'studyFirstSubmitDate': '2017-03-20', 'studyFirstSubmitQcDate': '2017-03-20', 'lastUpdatePostDateStruct': {'date': '2021-03-25', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-03-24', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-03-23', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Serious condition', 'timeFrame': 'During medical care event', 'description': 'Predefined serious condition'}], 'secondaryOutcomes': [{'measure': 'Mortality', 'timeFrame': '24hours and 30 days', 'description': '24h and 30 day mortality'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Unspecific symptoms', 'Soluvent urokinase plasminogen activator receptor', 'Lactate', 'Emergency Medical Services'], 'conditions': ['Serious Condition', 'Morality']}, 'referencesModule': {'references': [{'pmid': '34384460', 'type': 'DERIVED', 'citation': 'Ivic R, Nurmi J, Kurland L, Vicente V, Lindstrom V, Djarv T, Kaartinen J, Castren M, Bohm K. Soluble urokinase plasminogen activator receptor and lactate as prognostic biomarkers in patients presenting with non-specific chief complaints in the pre-hospital setting - the PRIUS-study. Scand J Trauma Resusc Emerg Med. 2021 Aug 12;29(1):116. doi: 10.1186/s13049-021-00908-z.'}]}, 'descriptionModule': {'briefSummary': 'This study evaluates the predictive value of soluvent urokinase plasminogen activator receptor (suPAR) and lactate with respect to serious conditions among patients presenting to the EMS with unspecific symptoms.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Unspecific symptoms presenting to the EMS', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Unspecific symptoms (not feeling well, decreased general health condition, unable to cope with usual daily activities, feeling weak)\n* Normal vital signs\n* Transported to ED\n* Able to give informed consent/ Next of kin gives informed consent\n\nExclusion Criteria:\n\n* Specific symptoms\n* under 18 years of age\n* Stays home / other caregiver than ED\n* Referral from caregiver\n* No personal numer (social security number)'}, 'identificationModule': {'nctId': 'NCT03089359', 'acronym': 'PRIUS', 'briefTitle': 'Prehospital Recognition and Identification of Unspecific Symptoms', 'organization': {'class': 'OTHER', 'fullName': 'Karolinska Institutet'}, 'officialTitle': 'Prehospital Recognition and Identification of Unspecific Symptoms', 'orgStudyIdInfo': {'id': 'PRIUS'}}, 'contactsLocationsModule': {'locations': [{'zip': '00029', 'city': 'Helsinki', 'country': 'Finland', 'facility': 'Helsinki University', 'geoPoint': {'lat': 60.16952, 'lon': 24.93545}}, {'zip': '11883', 'city': 'Stockholm', 'country': 'Sweden', 'facility': 'Karolinska Institute', 'geoPoint': {'lat': 59.32938, 'lon': 18.06871}}], 'overallOfficials': [{'name': 'Katarina Bohm, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Karolinska Institutet'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Karolinska Institutet', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'PhD', 'investigatorFullName': 'Katarina Bohm', 'investigatorAffiliation': 'Karolinska Institutet'}}}}