Ignite Creation Date:
2025-12-25 @ 2:31 AM
Ignite Modification Date:
2026-02-27 @ 5:10 PM
Study NCT ID:
NCT03908034
Status:
UNKNOWN
Last Update Posted:
2019-04-09
First Post:
2019-04-02
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Consumer Motivation for Disease Prevention
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D040242', 'term': 'Risk Reduction Behavior'}], 'ancestors': [{'id': 'D001519', 'term': 'Behavior'}]}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2019-04-02', 'size': 72907, 'label': 'Statistical Analysis Plan', 'hasIcf': False, 'hasSap': True, 'filename': 'SAP_000.pdf', 'typeAbbrev': 'SAP', 'uploadDate': '2019-04-03T06:09', 'hasProtocol': False}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR'], 'maskingDescription': 'Each participant will only receive the instruction pertaining to the arm to which he/she is assigned. The Research Assistant who conducts the study does not know about the hypothesis.'}, 'primaryPurpose': 'OTHER', 'interventionModel': 'FACTORIAL', 'interventionModelDescription': 'The study has a 2 (presence of uncontrollable factor: yes vs. no) ✕ 2 (Anticipated regret induction: yes vs. no) between-subject design. Participants will be randomly assigned to one of the 4 between-subject conditions.\n\nThere is also a within-subject variable. Each subject will respond to 10 rounds of decision task with 5 different levels of overall disease risk reduction brought by the removal of X. The 5 levels of risk reduction are: (i) Removal of X reduces disease risk from 60% to 50% ; (ii) 60% to 40%; (iii) 60% to 30%; (iv) 60% to 20%; (v) 60% to 10%.'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 200}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2019-04-04', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2019-04', 'completionDateStruct': {'date': '2019-07', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2019-04-05', 'studyFirstSubmitDate': '2019-04-02', 'studyFirstSubmitQcDate': '2019-04-05', 'lastUpdatePostDateStruct': {'date': '2019-04-09', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2019-04-09', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-07', 'type': 'ESTIMATED'}}, 'outcomesModule': {'otherOutcomes': [{'measure': 'Anticipated regret', 'timeFrame': 'Day 1: When responding to the questionnaire.', 'description': 'The exact question is: Some people may engage in the following thoughts when they make their decisions: "I may regret if I do not remove X and end up getting the disease" OR "I may regret if I remove X but still get the disease." To what extent have you engaged in any of these thoughts? (Measurement scale: 1 = not at all; 7 = a lot)'}, {'measure': 'Judgment of whether the removal of X is an opportunity to improve earnings', 'timeFrame': 'Day 1: When responding to the questionnaire.', 'description': 'The exact question is: Do you think the decision to remove X is an opportunity for you to improve your final earnings? (Measurement scale: 1 = not a good opportunity at all; 7 = a very good opportunity")'}, {'measure': 'Sense of control over the final outcome', 'timeFrame': 'Day 1: When responding to the questionnaire.', 'description': 'The exact question is: Do you think you have control over the outcome through your decision of whether or not to remove X? (Measurement scale: 1 = I have very little control… 7 = I have a lot of control)'}], 'primaryOutcomes': [{'measure': 'Decision to remove X', 'timeFrame': 'Day 1: When responding to the questionnaire', 'description': 'The decision to remove X (yes vs. no)'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Risk Reduction']}, 'referencesModule': {'references': [{'pmid': '29285871', 'type': 'BACKGROUND', 'citation': 'Binder S, Nuscheler R. Risk-taking in vaccination, surgery, and gambling environments: Evidence from a framed laboratory experiment. Health Econ. 2017 Dec;26 Suppl 3:76-96. doi: 10.1002/hec.3620.'}]}, 'descriptionModule': {'briefSummary': "The purpose of this study is to examine (1) how the causal structure of a disease influences people's disease prevention decisions; and (2) how the causal structure of a disease interacts with people's regret anticipation in determining their disease prevention decisions.", 'detailedDescription': "People sometimes have to deliberate on whether or not to remove a risk factor that may potentially cause a disease in the future. When a controllable risk factor (say, X) is the only factor that causes a disease, the decision to remove it may simply depend on the probabilistic relationship between X and an outcome, as well as the cost of removing X. However, little is known when other factors that are out of the decision-maker's control are also present. The main question being asked here is how does the presence of such uncontrollable factors change people's decision to remove X.\n\nSpecifically, the investigators consider two cases: a disease caused by a single controllable risk factor (say X) and a disease caused by two risk factors -- a controllable factor (X) and an uncontrollable factor (Y). In both cases, the removal of X can result in a meaningful reduction in overall disease risk. It is hypothesized that even when the magnitude of overall risk reduction brought by the removal of X is the same in the two cases, people would have a lower motivation to remove X in the latter case.\n\nThe investigators also examine how the presence of an uncontrollable risk factor interacts with the respondents' regret anticipation to influence their decision to remove X. In the context of the current research, regret anticipation could take one of the following forms: (a) feel regretful if one decides not to remove X and later develops the disease (b) feel regretful if one decides to remove X but still develops the disease. The investigators expect (a) to moderate the effect of uncontrollable risk factor on motivation to remove X."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* students enrolled in marketing courses at the Chinese University of Hong Kong\n\nExclusion Criteria:\n\n* None'}, 'identificationModule': {'nctId': 'NCT03908034', 'briefTitle': 'Consumer Motivation for Disease Prevention', 'organization': {'class': 'OTHER', 'fullName': 'Chinese University of Hong Kong'}, 'officialTitle': 'Consumer Motivation for Disease Prevention', 'orgStudyIdInfo': {'id': '14507018'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'NO_INTERVENTION', 'label': 'Uncontrollable factor ABSENT; NO anticipated regret induced', 'description': 'The experiment comprises 10 rounds of decision tasks. For each round, the participant begins with having 130 points, each worth $0.5 (Hong Kong dollars). Different numbers of points are deducted depending on the outcome in each round. After the 10 rounds, the computer randomly selects 1 of the rounds and the points from this round is paid in cash.\n\nThere is a chance for the participant to develop a disease. Without prevention, the chance of getting the disease is 60%. A cause, X, is identified for the disease. The participant has to decide whether or not to remove X. Removal of X reduces disease chance; the reduced chance varies between 10% and 50% across the 10 rounds and the exact level is communicated at the beginning of each round. The removal of X costs 30 points. Whether s/he ends up developing the disease or not is determined by a computerized lottery based on these chances. If s/he develops the disease, s/he will lose 100 points.'}, {'type': 'EXPERIMENTAL', 'label': 'Uncontrollable factor ABSENT; anticipated regret induced', 'description': 'Same description as in the "uncontrollable factor absent, no anticipated regret induced" arm, except that the participants are induced to think to what extent they will feel regretful: a) if s/he decides not to remove X but ends up developing the disease and b) if s/he decides to remove X but still gets the disease.', 'interventionNames': ['Other: induction of anticipated regret']}, {'type': 'EXPERIMENTAL', 'label': 'Uncontrollable factor PRESENT; NO anticipated regret induced', 'description': 'The experiment comprises 10 rounds of decision tasks. For each round, the participant begins with having 130 points, each worth $0.5. Different numbers of points are deducted depending on the outcome in each round. After the 10 rounds, the computer randomly selects 1 of the rounds and the points from this round is paid in cash.\n\nThere is a chance for the participant to develop a disease. Without prevention, the chance of getting the disease is 60%. Two causes, X and Y, are identified for the disease. The participant has to decide whether or not to remove X. Removal of X reduces disease chance; the reduced chance varies between 10% and 50% across the 10 rounds and the exact level is communicated at the beginning of each round. The removal of X costs 30 points. Whether s/he ends up developing the disease or not is determined by a computerized lottery based on these chances. If s/he develops the disease, s/he will lose 100 points.', 'interventionNames': ['Other: presence of uncontrollable risk factor']}, {'type': 'EXPERIMENTAL', 'label': 'Uncontrollable factor PRESENT; anticipated regret induced', 'description': 'Same as the "uncontrollable factor present, no anticipated regret induced" arm, except that the participants are induced to think to what extent they will feel regretful: a) if s/he decides not to remove X but ends up developing the disease and b) if s/he decides to remove X but still gets the disease.', 'interventionNames': ['Other: presence of uncontrollable risk factor', 'Other: induction of anticipated regret']}], 'interventions': [{'name': 'presence of uncontrollable risk factor', 'type': 'OTHER', 'description': 'the presence of an uncontrollable / unremovable risk factor for a disease', 'armGroupLabels': ['Uncontrollable factor PRESENT; NO anticipated regret induced', 'Uncontrollable factor PRESENT; anticipated regret induced']}, {'name': 'induction of anticipated regret', 'type': 'OTHER', 'description': 'higher level of elaboration on potential regret', 'armGroupLabels': ['Uncontrollable factor ABSENT; anticipated regret induced', 'Uncontrollable factor PRESENT; anticipated regret induced']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Hong Kong', 'status': 'RECRUITING', 'country': 'Hong Kong', 'contacts': [{'name': 'Wing Man Yeung, PhD', 'role': 'CONTACT'}], 'facility': 'Chinese University of Hong Kong', 'geoPoint': {'lat': 22.27832, 'lon': 114.17469}}], 'centralContacts': [{'name': 'Wing Man Yeung, PhD', 'role': 'CONTACT', 'email': 'cyeung@cuhk.edu.hk', 'phone': '(852) 39439297'}], 'overallOfficials': [{'name': 'Wing Man Yeung, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Chinese University of Hong Kong'}]}, 'ipdSharingStatementModule': {'infoTypes': ['STUDY_PROTOCOL', 'SAP', 'ANALYTIC_CODE'], 'timeFrame': 'Data will become available after manuscript is published, for 5 years starting from publication date.', 'ipdSharing': 'YES', 'description': 'Data will be uploaded to file sharing sites for sharing. Any identifying information will be removed before data sharing.', 'accessCriteria': 'Data will only be made available for research purpose.'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Chinese University of Hong Kong', 'class': 'OTHER'}, 'collaborators': [{'name': 'University of Toronto', 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor of Marketing', 'investigatorFullName': 'Yeung Wing Man', 'investigatorAffiliation': 'Chinese University of Hong Kong'}}}}