Ignite Creation Date:
2025-12-25 @ 2:29 AM
Ignite Modification Date:
2026-03-02 @ 4:24 PM
Study NCT ID:
NCT02294734
Status:
COMPLETED
Last Update Posted:
2021-08-12
First Post:
2014-11-17
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Sponsor:
Organization:
Raw JSON
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GSK supports the publication of results from all centers of a multi-center trial but requests that reports based on single-site data not precede the primary publication of the entire clinical trial.', 'restrictionType': 'OTHER', 'piSponsorEmployee': False, 'restrictiveAgreement': True}}, 'adverseEventsModule': {'timeFrame': 'Serious adverse events (SAEs) and non-serious AEs were collected from the start of study medication up to approximately 100 days.', 'description': 'SAEs and non-serious AEs were collected in members of the Safety Population, comprised of all participants who received at least one dose of investigational product.', 'eventGroups': [{'id': 'EG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.', 'otherNumAtRisk': 63, 'otherNumAffected': 15, 'seriousNumAtRisk': 63, 'seriousNumAffected': 10}, {'id': 'EG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.', 'otherNumAtRisk': 63, 'otherNumAffected': 31, 'seriousNumAtRisk': 63, 'seriousNumAffected': 8}], 'otherEvents': [{'term': 'Dry mouth', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 5}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 2}], 'organSystem': 'Gastrointestinal disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Headache', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 5}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 7}], 'organSystem': 'Nervous system disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Cough', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 2}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 22}], 'organSystem': 'Respiratory, thoracic and mediastinal disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Hypertension', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 4}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'Vascular disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}], 'seriousEvents': [{'term': 'Coronary artery stenosis', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 0}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 1}], 'organSystem': 'Cardiac disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Constipation', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'Gastrointestinal disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Malaise', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'General disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Lower respiratory tract infection', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'Infections and infestations', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Pneumonia', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 0}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 1}], 'organSystem': 'Infections and infestations', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Clostridium difficile infection', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 0}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 1}], 'organSystem': 'Infections and infestations', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Blood sodium decreased', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 0}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 1}], 'organSystem': 'Investigations', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Anxiety', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'Psychiatric disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Suicide attempt', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 63, 'numAffected': 0}], 'organSystem': 'Psychiatric disorders', 'assessmentType': 'SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA 18.1'}, {'term': 'Chronic obstructive pulmonary disease', 'stats': [{'groupId': 'EG000', 'numAtRisk': 63, 'numAffected': 9}, {'groupId': 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{'value': '0.948', 'groupId': 'OG001', 'lowerLimit': '0.858', 'upperLimit': '1.048'}]}]}, {'title': 'TLC; Longitudinal; Lobes; LLL; D12 , n =57, 59', 'categories': [{'measurements': [{'value': '1.074', 'groupId': 'OG000', 'lowerLimit': '0.917', 'upperLimit': '1.258'}, {'value': '0.934', 'groupId': 'OG001', 'lowerLimit': '0.844', 'upperLimit': '1.035'}]}]}, {'title': 'TLC; Longitudinal; Lobes; LLL; D28 ,n =55, 59', 'categories': [{'measurements': [{'value': '1.075', 'groupId': 'OG000', 'lowerLimit': '0.901', 'upperLimit': '1.282'}, {'value': '0.993', 'groupId': 'OG001', 'lowerLimit': '0.891', 'upperLimit': '1.107'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12 , n =58, 57', 'categories': [{'measurements': [{'value': '1.040', 'groupId': 'OG000', 'lowerLimit': '0.978', 'upperLimit': '1.105'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.940', 'upperLimit': '1.038'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 57', 'categories': [{'measurements': [{'value': '1.020', 'groupId': 'OG000', 'lowerLimit': '0.949', 'upperLimit': '1.097'}, {'value': '0.981', 'groupId': 'OG001', 'lowerLimit': '0.925', 'upperLimit': '1.040'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; D12D28 , n =55, 56', 'categories': [{'measurements': [{'value': '0.971', 'groupId': 'OG000', 'lowerLimit': '0.908', 'upperLimit': '1.039'}, {'value': '1.002', 'groupId': 'OG001', 'lowerLimit': '0.956', 'upperLimit': '1.050'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.022', 'groupId': 'OG000', 'lowerLimit': '0.961', 'upperLimit': '1.088'}, {'value': '1.001', 'groupId': 'OG001', 'lowerLimit': '0.950', 'upperLimit': '1.055'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.035', 'groupId': 'OG000', 'lowerLimit': '0.962', 'upperLimit': '1.113'}, {'value': '0.991', 'groupId': 'OG001', 'lowerLimit': '0.933', 'upperLimit': '1.052'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '1.007', 'groupId': 'OG000', 'lowerLimit': '0.933', 'upperLimit': '1.086'}, {'value': '1.002', 'groupId': 'OG001', 'lowerLimit': '0.956', 'upperLimit': '1.050'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD12 , n =57, 58', 'categories': [{'measurements': [{'value': '1.029', 'groupId': 'OG000', 'lowerLimit': '0.948', 'upperLimit': '1.116'}, {'value': '0.934', 'groupId': 'OG001', 'lowerLimit': '0.870', 'upperLimit': '1.003'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '1.020', 'groupId': 'OG000', 'lowerLimit': '0.933', 'upperLimit': '1.116'}, {'value': '0.932', 'groupId': 'OG001', 'lowerLimit': '0.877', 'upperLimit': '0.991'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; D12D28 , n =55, 57', 'categories': [{'measurements': [{'value': '0.980', 'groupId': 'OG000', 'lowerLimit': '0.904', 'upperLimit': '1.063'}, {'value': '1.008', 'groupId': 'OG001', 'lowerLimit': '0.942', 'upperLimit': '1.078'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.022', 'groupId': 'OG000', 'lowerLimit': '0.940', 'upperLimit': '1.112'}, {'value': '0.932', 'groupId': 'OG001', 'lowerLimit': '0.871', 'upperLimit': '0.996'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '0.984', 'groupId': 'OG000', 'lowerLimit': '0.897', 'upperLimit': '1.078'}, {'value': '0.944', 'groupId': 'OG001', 'lowerLimit': '0.884', 'upperLimit': '1.008'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.962', 'groupId': 'OG000', 'lowerLimit': '0.881', 'upperLimit': '1.051'}, {'value': '1.027', 'groupId': 'OG001', 'lowerLimit': '0.980', 'upperLimit': '1.076'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12 , n =57, 59', 'categories': [{'measurements': [{'value': '1.024', 'groupId': 'OG000', 'lowerLimit': '0.939', 'upperLimit': '1.117'}, {'value': '0.967', 'groupId': 'OG001', 'lowerLimit': '0.908', 'upperLimit': '1.030'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28 , n=55, 59', 'categories': [{'measurements': [{'value': '1.025', 'groupId': 'OG000', 'lowerLimit': '0.933', 'upperLimit': '1.125'}, {'value': '0.972', 'groupId': 'OG001', 'lowerLimit': '0.907', 'upperLimit': '1.043'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; D12D28 , n =54, 58', 'categories': [{'measurements': [{'value': '0.984', 'groupId': 'OG000', 'lowerLimit': '0.911', 'upperLimit': '1.062'}, {'value': '1.017', 'groupId': 'OG001', 'lowerLimit': '0.970', 'upperLimit': '1.065'}]}]}, {'title': 'TLC; Longitudinal;Region; Upper; D12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.031', 'groupId': 'OG000', 'lowerLimit': '0.935', 'upperLimit': '1.137'}, {'value': '0.983', 'groupId': 'OG001', 'lowerLimit': '0.922', 'upperLimit': '1.049'}]}]}, {'title': 'TLC; Longitudinal; Region; Upper; D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.046', 'groupId': 'OG000', 'lowerLimit': '0.918', 'upperLimit': '1.191'}, {'value': '0.995', 'groupId': 'OG001', 'lowerLimit': '0.928', 'upperLimit': '1.067'}]}]}, {'title': 'TLC; Longitudinal; Region; Lower; D12 , n=58, 59', 'categories': [{'measurements': [{'value': '1.051', 'groupId': 'OG000', 'lowerLimit': '0.909', 'upperLimit': '1.215'}, {'value': '0.924', 'groupId': 'OG001', 'lowerLimit': '0.840', 'upperLimit': '1.017'}]}]}, {'title': 'TLC; Longitudinal; Region; Lower; D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.037', 'groupId': 'OG000', 'lowerLimit': '0.879', 'upperLimit': '1.223'}, {'value': '0.974', 'groupId': 'OG001', 'lowerLimit': '0.883', 'upperLimit': '1.074'}]}]}, {'title': 'TLC; Longitudinal; Region;Central; D12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.001', 'groupId': 'OG000', 'lowerLimit': '0.971', 'upperLimit': '1.033'}, {'value': '0.991', 'groupId': 'OG001', 'lowerLimit': '0.971', 'upperLimit': '1.012'}]}]}, {'title': 'TLC; Longitudinal;Region; Central; D28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.006', 'groupId': 'OG000', 'lowerLimit': '0.979', 'upperLimit': '1.033'}, {'value': '0.992', 'groupId': 'OG001', 'lowerLimit': '0.972', 'upperLimit': '1.013'}]}]}, {'title': 'TLC; Longitudinal; Region; Distal; D12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.043', 'groupId': 'OG000', 'lowerLimit': '0.931', 'upperLimit': '1.168'}, {'value': '0.949', 'groupId': 'OG001', 'lowerLimit': '0.883', 'upperLimit': '1.021'}]}]}, {'title': 'TLC; Longitudinal; Region; Distal D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.039', 'groupId': 'OG000', 'lowerLimit': '0.902', 'upperLimit': '1.197'}, {'value': '0.982', 'groupId': 'OG001', 'lowerLimit': '0.910', 'upperLimit': '1.060'}]}]}, {'title': 'TLC; Longitudinal; Region;Total; D12, n =58, 59', 'categories': [{'measurements': [{'value': '1.009', 'groupId': 'OG000', 'lowerLimit': '0.969', 'upperLimit': '1.051'}, {'value': '0.982', 'groupId': 'OG001', 'lowerLimit': '0.958', 'upperLimit': '1.006'}]}]}, {'title': 'TLC; Longitudinal; Region; Total; D28 ,n =56, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.967', 'upperLimit': '1.044'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.013'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.028', 'groupId': 'OG000', 'lowerLimit': '0.969', 'upperLimit': '1.090'}, {'value': '0.992', 'groupId': 'OG001', 'lowerLimit': '0.944', 'upperLimit': '1.041'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '1.021', 'groupId': 'OG000', 'lowerLimit': '0.953', 'upperLimit': '1.095'}, {'value': '0.984', 'groupId': 'OG001', 'lowerLimit': '0.932', 'upperLimit': '1.040'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '0.985', 'groupId': 'OG000', 'lowerLimit': '0.922', 'upperLimit': '1.054'}, {'value': '1.003', 'groupId': 'OG001', 'lowerLimit': '0.962', 'upperLimit': '1.046'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.021', 'groupId': 'OG000', 'lowerLimit': '0.943', 'upperLimit': '1.105'}, {'value': '0.954', 'groupId': 'OG001', 'lowerLimit': '0.897', 'upperLimit': '1.014'}]}]}, {'title': 'TLC; Scan Trimmed; Region; Lower; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '0.996', 'groupId': 'OG000', 'lowerLimit': '0.916', 'upperLimit': '1.083'}, {'value': '0.960', 'groupId': 'OG001', 'lowerLimit': '0.899', 'upperLimit': '1.025'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '0.972', 'groupId': 'OG000', 'lowerLimit': '0.899', 'upperLimit': '1.052'}, {'value': '1.018', 'groupId': 'OG001', 'lowerLimit': '0.977', 'upperLimit': '1.060'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Central; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.000', 'groupId': 'OG000', 'lowerLimit': '0.972', 'upperLimit': '1.029'}, {'value': '0.997', 'groupId': 'OG001', 'lowerLimit': '0.975', 'upperLimit': '1.020'}]}]}, {'title': 'TLC;Scan Trimmed; Region Central; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.981', 'upperLimit': '1.030'}, {'value': '0.995', 'groupId': 'OG001', 'lowerLimit': '0.972', 'upperLimit': '1.018'}]}]}, {'title': 'TLC;Scan Trimmed;Region Central; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '1.004', 'groupId': 'OG000', 'lowerLimit': '0.981', 'upperLimit': '1.028'}, {'value': '0.998', 'groupId': 'OG001', 'lowerLimit': '0.984', 'upperLimit': '1.012'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Distal; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.025', 'groupId': 'OG000', 'lowerLimit': '0.960', 'upperLimit': '1.095'}, {'value': '0.972', 'groupId': 'OG001', 'lowerLimit': '0.922', 'upperLimit': '1.025'}]}]}, {'title': 'TLC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.008', 'groupId': 'OG000', 'lowerLimit': '0.936', 'upperLimit': '1.086'}, {'value': '0.972', 'groupId': 'OG001', 'lowerLimit': '0.919', 'upperLimit': '1.029'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Distal; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.978', 'groupId': 'OG000', 'lowerLimit': '0.912', 'upperLimit': '1.050'}, {'value': '1.011', 'groupId': 'OG001', 'lowerLimit': '0.973', 'upperLimit': '1.051'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Total; SCRD12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.973', 'upperLimit': '1.037'}, {'value': '0.991', 'groupId': 'OG001', 'lowerLimit': '0.967', 'upperLimit': '1.017'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Total; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.004', 'groupId': 'OG000', 'lowerLimit': '0.976', 'upperLimit': '1.032'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.965', 'upperLimit': '1.014'}]}]}, {'title': 'TLC; Scan Trimmed;Region;Total; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.997', 'groupId': 'OG000', 'lowerLimit': '0.970', 'upperLimit': '1.025'}, {'value': '1.000', 'groupId': 'OG001', 'lowerLimit': '0.984', 'upperLimit': '1.017'}]}]}], 'analyses': [{'pValue': '60.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.85', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.21', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.19', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.47', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '74.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.48', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.29', 'ciLowerLimit': '1.06', 'ciUpperLimit': '1.58', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '13.98', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.87', 'ciLowerLimit': '0.66', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RML; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.92', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.28', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.62', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RML; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '80.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.14', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.54', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.79', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.30', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.66', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '51.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '90.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.15', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '54.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.45', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.24', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.09', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.21', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '62.95', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.86', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.12', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.26', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.16', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.09', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.20', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.15', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.51', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.12', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.59', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.31', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '61.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.23', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.63', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.15', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.34', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.No'}, {'pValue': '94.02', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.12', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.29', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '53.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '70.84', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '74.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '65.43', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.24', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal;Region; Upper; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.19', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Upper; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.34', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Lower; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '91.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.15', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.41', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Lower; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '76.81', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region;Central; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '67.01', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal;Region; Central; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.91', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.85', 'ciUpperLimit': '1.27', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Distal; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.47', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.18', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Distal D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '72.17', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region;Total; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '74.38', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Total; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '53.85', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.02', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.23', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '92.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '54.65', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.93', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.23', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '77.57', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '77.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '78.42', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '44.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '52.79', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.51', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.24', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region; Distal; SCRD28 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '93.16', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '73.70', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.04', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '52.58', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '15.85', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.69', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '52.25', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.48', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.12', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.88', 'ciLowerLimit': '0.72', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RML; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '16.95', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.78', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RML; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '50.40', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '7.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.76', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LLL; D12 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '56.35', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '4.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '24.79', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '77.08', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '23.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '18.58', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '44.94', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '2.21', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.80', 'ciUpperLimit': '1.00', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.83', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.60', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '3.23', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.90', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '20.83', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.60', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '7.90', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '23.39', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '76.16', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '22.54', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal;Region; Upper; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '58.17', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Upper; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.22', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.76', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Lower; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '55.85', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Lower; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '25.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region;Central; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '18.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal;Region; Cetral; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '8.12', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.82', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Distal; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '57.39', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Distal D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '10.00', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region;Total; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '29.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Total; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '12.63', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '32.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; SCRD28 The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '69.92', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '33.63', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '41.38', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '24.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '29.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '7.13', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '32.91', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '21.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '24.49', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '55.52', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'GEOMETRIC_MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': "siVaw is a measure of the volume in an individual's airway corrected for their lobar volume derived from the high resolution computed tomography (HRCT). It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at longitudinal time points: Screening, Day 12 \\& Day 28 and at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points and SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).", 'unitOfMeasure': 'Milliliter/Liter (mL/L)', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'Intention to Treat (ITT) Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Imaging Airways Volume: iVaw, Measured at FRC and TLC Scan Conditions, Presented in Longitudinal and Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC; Longitudinal; Lobes; RUL; D12 , n =54, 59', 'categories': [{'measurements': [{'value': '1.020', 'groupId': 'OG000', 'lowerLimit': '0.838', 'upperLimit': '1.242'}, {'value': '1.058', 'groupId': 'OG001', 'lowerLimit': '0.930', 'upperLimit': '1.203'}]}]}, {'title': 'FRC; Longitudinal; Lobes; RUL; D28 , n =56, 58', 'categories': [{'measurements': [{'value': '0.960', 'groupId': 'OG000', 'lowerLimit': '0.755', 'upperLimit': '1.220'}, {'value': '1.121', 'groupId': 'OG001', 'lowerLimit': '0.965', 'upperLimit': '1.301'}]}]}, {'title': 'FRC; Longitudinal; Lobes; LUL; D12 , n=56, 59', 'categories': [{'measurements': [{'value': '0.951', 'groupId': 'OG000', 'lowerLimit': '0.789', 'upperLimit': '1.145'}, {'value': '0.999', 'groupId': 'OG001', 'lowerLimit': '0.866', 'upperLimit': '1.151'}]}]}, {'title': 'FRC; Longitudinal; Lobes; LUL; D28 , n =56, 58', 'categories': [{'measurements': [{'value': '0.876', 'groupId': 'OG000', 'lowerLimit': '0.727', 'upperLimit': '1.055'}, {'value': '1.108', 'groupId': 'OG001', 'lowerLimit': '0.938', 'upperLimit': '1.309'}]}]}, {'title': 'FRC; Longitudinal; Lobes; RML; D12 , n =53, 59', 'categories': [{'measurements': [{'value': '0.905', 'groupId': 'OG000', 'lowerLimit': '0.746', 'upperLimit': '1.098'}, {'value': '0.869', 'groupId': 'OG001', 'lowerLimit': '0.694', 'upperLimit': '1.089'}]}]}, {'title': 'FRC; Longitudinal; Lobes; RML; D28 , n=53, 58', 'categories': [{'measurements': [{'value': '0.835', 'groupId': 'OG000', 'lowerLimit': '0.655', 'upperLimit': '1.064'}, {'value': '1.013', 'groupId': 'OG001', 'lowerLimit': '0.870', 'upperLimit': '1.180'}]}]}, {'title': 'FRC; Longitudinal; Lobes; RLL; D12 , n =54, 59', 'categories': [{'measurements': [{'value': '0.889', 'groupId': 'OG000', 'lowerLimit': '0.669', 'upperLimit': '1.182'}, {'value': '1.119', 'groupId': 'OG001', 'lowerLimit': '0.892', 'upperLimit': '1.404'}]}]}, {'title': 'FRC; Longitudinal; Lobes; RLL; D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.850', 'groupId': 'OG000', 'lowerLimit': '0.634', 'upperLimit': '1.140'}, {'value': '1.177', 'groupId': 'OG001', 'lowerLimit': '0.977', 'upperLimit': '1.417'}]}]}, {'title': 'FRC; Longitudinal; Lobes; LLL; D12 , n =53, 58', 'categories': [{'measurements': [{'value': '1.017', 'groupId': 'OG000', 'lowerLimit': '0.853', 'upperLimit': '1.212'}, {'value': '1.067', 'groupId': 'OG001', 'lowerLimit': '0.881', 'upperLimit': '1.293'}]}]}, {'title': 'FRC; Longitudinal; Lobes; LLL; D28 ,n =54, 58', 'categories': [{'measurements': [{'value': '0.980', 'groupId': 'OG000', 'lowerLimit': '0.784', 'upperLimit': '1.226'}, {'value': '1.187', 'groupId': 'OG001', 'lowerLimit': '0.992', 'upperLimit': '1.421'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12 , n =54, 59', 'categories': [{'measurements': [{'value': '1.035', 'groupId': 'OG000', 'lowerLimit': '0.942', 'upperLimit': '1.137'}, {'value': '1.006', 'groupId': 'OG001', 'lowerLimit': '0.927', 'upperLimit': '1.091'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.976', 'groupId': 'OG000', 'lowerLimit': '0.872', 'upperLimit': '1.091'}, {'value': '1.027', 'groupId': 'OG001', 'lowerLimit': '0.938', 'upperLimit': '1.124'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; D12D28 , n =51, 57', 'categories': [{'measurements': [{'value': '0.927', 'groupId': 'OG000', 'lowerLimit': '0.861', 'upperLimit': '0.997'}, {'value': '1.018', 'groupId': 'OG001', 'lowerLimit': '0.948', 'upperLimit': '1.092'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.954', 'groupId': 'OG000', 'lowerLimit': '0.870', 'upperLimit': '1.048'}, {'value': '1.010', 'groupId': 'OG001', 'lowerLimit': '0.932', 'upperLimit': '1.095'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.933', 'groupId': 'OG000', 'lowerLimit': '0.846', 'upperLimit': '1.029'}, {'value': '1.035', 'groupId': 'OG001', 'lowerLimit': '0.946', 'upperLimit': '1.133'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '0.981', 'groupId': 'OG000', 'lowerLimit': '0.902', 'upperLimit': '1.068'}, {'value': '1.029', 'groupId': 'OG001', 'lowerLimit': '0.956', 'upperLimit': '1.107'}]}]}, {'title': 'FRC; 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Longitudinal; Region; Upper; D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.049', 'groupId': 'OG000', 'lowerLimit': '0.909', 'upperLimit': '1.211'}, {'value': '0.994', 'groupId': 'OG001', 'lowerLimit': '0.924', 'upperLimit': '1.069'}]}]}, {'title': 'TLC; Longitudinal; Region; Lower; D12 , n=58, 59', 'categories': [{'measurements': [{'value': '1.061', 'groupId': 'OG000', 'lowerLimit': '0.911', 'upperLimit': '1.235'}, {'value': '0.921', 'groupId': 'OG001', 'lowerLimit': '0.830', 'upperLimit': '1.022'}]}]}, {'title': 'TLC; Longitudinal; Region; Lower; D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.037', 'groupId': 'OG000', 'lowerLimit': '0.867', 'upperLimit': '1.241'}, {'value': '0.977', 'groupId': 'OG001', 'lowerLimit': '0.876', 'upperLimit': '1.089'}]}]}, {'title': 'TLC; Longitudinal; Region;Central; D12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.006', 'groupId': 'OG000', 'lowerLimit': '0.972', 'upperLimit': '1.042'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.970', 'upperLimit': '1.007'}]}]}, {'title': 'TLC; Longitudinal;Region; Cetral; D28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.007', 'groupId': 'OG000', 'lowerLimit': '0.968', 'upperLimit': '1.049'}, {'value': '0.993', 'groupId': 'OG001', 'lowerLimit': '0.973', 'upperLimit': '1.013'}]}]}, {'title': 'TLC; Longitudinal; Region; Distal; D12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.048', 'groupId': 'OG000', 'lowerLimit': '0.930', 'upperLimit': '1.182'}, {'value': '0.947', 'groupId': 'OG001', 'lowerLimit': '0.876', 'upperLimit': '1.023'}]}]}, {'title': 'TLC; Longitudinal; Region; Distal D28 , n =56, 59', 'categories': [{'measurements': [{'value': '1.041', 'groupId': 'OG000', 'lowerLimit': '0.891', 'upperLimit': '1.215'}, {'value': '0.983', 'groupId': 'OG001', 'lowerLimit': '0.905', 'upperLimit': '1.067'}]}]}, {'title': 'TLC; Longitudinal; Region;Total; D12, n =58, 59', 'categories': [{'measurements': [{'value': '1.014', 'groupId': 'OG000', 'lowerLimit': '0.968', 'upperLimit': '1.062'}, {'value': '0.979', 'groupId': 'OG001', 'lowerLimit': '0.954', 'upperLimit': '1.004'}]}]}, {'title': 'TLC; Longitudinal; Region; Total; D28 ,n =56, 59', 'categories': [{'measurements': [{'value': '1.007', 'groupId': 'OG000', 'lowerLimit': '0.955', 'upperLimit': '1.061'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.963', 'upperLimit': '1.016'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.033', 'groupId': 'OG000', 'lowerLimit': '0.969', 'upperLimit': '1.102'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.940', 'upperLimit': '1.041'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '1.025', 'groupId': 'OG000', 'lowerLimit': '0.945', 'upperLimit': '1.111'}, {'value': '0.983', 'groupId': 'OG001', 'lowerLimit': '0.929', 'upperLimit': '1.040'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '0.983', 'groupId': 'OG000', 'lowerLimit': '0.915', 'upperLimit': '1.055'}, {'value': '1.006', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.049'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.030', 'groupId': 'OG000', 'lowerLimit': '0.949', 'upperLimit': '1.118'}, {'value': '0.951', 'groupId': 'OG001', 'lowerLimit': '0.894', 'upperLimit': '1.011'}]}]}, {'title': 'TLC; Scan Trimmed; Region; Lower; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '0.997', 'groupId': 'OG000', 'lowerLimit': '0.904', 'upperLimit': '1.099'}, {'value': '0.963', 'groupId': 'OG001', 'lowerLimit': '0.903', 'upperLimit': '1.027'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '0.964', 'groupId': 'OG000', 'lowerLimit': '0.889', 'upperLimit': '1.045'}, {'value': '1.025', 'groupId': 'OG001', 'lowerLimit': '0.985', 'upperLimit': '1.067'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Central; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.973', 'upperLimit': '1.037'}, {'value': '0.994', 'groupId': 'OG001', 'lowerLimit': '0.976', 'upperLimit': '1.013'}]}]}, {'title': 'TLC;Scan Trimmed; Region Central; SCRD28 ,n=56, 59', 'categories': [{'measurements': [{'value': '1.007', 'groupId': 'OG000', 'lowerLimit': '0.971', 'upperLimit': '1.044'}, {'value': '0.995', 'groupId': 'OG001', 'lowerLimit': '0.977', 'upperLimit': '1.014'}]}]}, {'title': 'TLC;Scan Trimmed;Region Central; D12D28 ,n =55, 58', 'categories': [{'measurements': [{'value': '1.000', 'groupId': 'OG000', 'lowerLimit': '0.980', 'upperLimit': '1.022'}, {'value': '1.003', 'groupId': 'OG001', 'lowerLimit': '0.991', 'upperLimit': '1.015'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Distal; SCRD12 ,n =58, 59', 'categories': [{'measurements': [{'value': '1.030', 'groupId': 'OG000', 'lowerLimit': '0.961', 'upperLimit': '1.105'}, {'value': '0.969', 'groupId': 'OG001', 'lowerLimit': '0.918', 'upperLimit': '1.023'}]}]}, {'title': 'TLC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.010', 'groupId': 'OG000', 'lowerLimit': '0.927', 'upperLimit': '1.100'}, {'value': '0.973', 'groupId': 'OG001', 'lowerLimit': '0.919', 'upperLimit': '1.030'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Distal; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.975', 'groupId': 'OG000', 'lowerLimit': '0.906', 'upperLimit': '1.04'}, {'value': '1.016', 'groupId': 'OG001', 'lowerLimit': '0.978', 'upperLimit': '1.057'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Total; SCRD12 , n =58, 59', 'categories': [{'measurements': [{'value': '1.010', 'groupId': 'OG000', 'lowerLimit': '0.974', 'upperLimit': '1.046'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.967', 'upperLimit': '1.011'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Total; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '1.006', 'groupId': 'OG000', 'lowerLimit': '0.966', 'upperLimit': '1.047'}, {'value': '0.990', 'groupId': 'OG001', 'lowerLimit': '0.968', 'upperLimit': '1.012'}]}]}, {'title': 'TLC; Scan Trimmed;Region;Total; D12D28 , n =55, 58', 'categories': [{'measurements': [{'value': '0.993', 'groupId': 'OG000', 'lowerLimit': '0.968', 'upperLimit': '1.019'}, {'value': '1.005', 'groupId': 'OG001', 'lowerLimit': '0.990', 'upperLimit': '1.020'}]}]}], 'analyses': [{'pValue': '59.55', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': '(FRC; Longitudinal; Lobes; RUL; D12, The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.01', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.18', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.46', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': '(FRC; Longitudinal; Lobes; RUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '82.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.33', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LUL; D12, The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.22', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.31', 'ciLowerLimit': '1.06', 'ciUpperLimit': '1.61', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '46.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.29', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RML; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.30', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.29', 'ciLowerLimit': '1.02', 'ciUpperLimit': '1.64', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RML; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '92.60', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.25', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.70', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.01', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.38', 'ciLowerLimit': '1.05', 'ciUpperLimit': '1.81', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; RLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '58.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.82', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Lobes; LLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '67.37', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.35', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.14', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.29', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.86', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.23', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.18', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.16', 'ciLowerLimit': '1.02', 'ciUpperLimit': '1.31', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '91.94', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '55.32', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.17', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.15', 'ciLowerLimit': '1.00', 'ciUpperLimit': '1.32', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.57', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.14', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.32', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '79.13', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.27', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.54', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '1.05', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.14', 'ciLowerLimit': '1.00', 'ciUpperLimit': '1.30', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '71.94', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '85.30', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.23', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '82.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '72.55', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.27', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal;Region; Upper; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '1.02', 'ciUpperLimit': '1.47', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Upper; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '78.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.11', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.43', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Lower; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.23', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.52', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Lower; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '91.11', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region;Central; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '89.30', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal;Region; Cetral; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '74.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.32', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Distal; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.25', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.23', 'ciLowerLimit': '1.02', 'ciUpperLimit': '1.48', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Distal D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region;Total; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '91.54', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.15', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Longitudinal; Region; Total; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '68.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.19', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.27', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.74', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.83', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.12', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '79.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Central; SCRD12 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '47.62', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '71.55', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.15', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Bayesian repeated measures model', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '93.68', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.58', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '1.00', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '56.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '13.08', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.85', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '52.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '60.75', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LUL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.23', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.92', 'ciUpperLimit': '1.20', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LUL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '28.14', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.78', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RML; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '38.43', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RML; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '25.21', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.80', 'ciUpperLimit': '1.12', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.73', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.27', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; RLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.90', 'ciLowerLimit': '0.76', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LLL; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.21', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Lobes; LLL; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '4.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '30.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '80.34', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '25.65', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '24.36', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.45', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '1.95', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.81', 'ciUpperLimit': '0.99', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '14.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.85', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '80.61', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '3.30', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.91', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12.The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '42.22', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.09', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.20', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; D12D28The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.38', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.83', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '28.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.39', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.05', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.14', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '23.27', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Upper; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '57.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Upper; D28.The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.90', 'ciLowerLimit': '0.77', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Lower; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '70.73', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.22', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Lower; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '25.61', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Central; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '44.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Cetral; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '10.14', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.82', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Distal; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '62.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Distal D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '11.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Total; D12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '51.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Longitudinal; Region; Total; D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.54', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.88', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '30.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '73.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '4.64', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.83', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model.', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '42.13', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '93.33', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '27.33', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '34.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '58.42', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '5.93', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '35.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.41', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '13.52', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '32.84', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Total; SCRD28 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '78.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'GEOMETRIC_MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'iVaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. Data was collected at longitudinal time points: Screening, Day 12 \\& Day 28 and at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points and SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).', 'unitOfMeasure': 'Milliliter (mL)', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Imaging Airways Resistance ( iRaw) Measured at FRC and TLC Scan Conditions, Presented in Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12 , n =54, 59', 'categories': [{'measurements': [{'value': '0.908', 'groupId': 'OG000', 'lowerLimit': '0.620', 'upperLimit': '1.330'}, {'value': '0.948', 'groupId': 'OG001', 'lowerLimit': '0.693', 'upperLimit': '1.296'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.849', 'groupId': 'OG000', 'lowerLimit': '0.529', 'upperLimit': '1.362'}, {'value': '0.958', 'groupId': 'OG001', 'lowerLimit': '0.701', 'upperLimit': '1.309'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; D12D28 , n =51, 57', 'categories': [{'measurements': [{'value': '1.039', 'groupId': 'OG000', 'lowerLimit': '0.715', 'upperLimit': '1.510'}, {'value': '0.898', 'groupId': 'OG001', 'lowerLimit': '0.697', 'upperLimit': '1.157'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.982', 'groupId': 'OG000', 'lowerLimit': '0.687', 'upperLimit': '1.403'}, {'value': '0.946', 'groupId': 'OG001', 'lowerLimit': '0.706', 'upperLimit': '1.267'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.937', 'groupId': 'OG000', 'lowerLimit': '0.620', 'upperLimit': '1.417'}, {'value': '0.820', 'groupId': 'OG001', 'lowerLimit': '0.568', 'upperLimit': '1.186'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '0.842', 'groupId': 'OG000', 'lowerLimit': '0.603', 'upperLimit': '1.176'}, {'value': '0.934', 'groupId': 'OG001', 'lowerLimit': '0.703', 'upperLimit': '1.241'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; SCRD12 , n =53, 59', 'categories': [{'measurements': [{'value': '1.022', 'groupId': 'OG000', 'lowerLimit': '0.667', 'upperLimit': '1.568'}, {'value': '0.998', 'groupId': 'OG001', 'lowerLimit': '0.656', 'upperLimit': '1.520'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; SCRD28 , n=53, 58', 'categories': [{'measurements': [{'value': '1.378', 'groupId': 'OG000', 'lowerLimit': '0.865', 'upperLimit': '2.196'}, {'value': '0.886', 'groupId': 'OG001', 'lowerLimit': '0.632', 'upperLimit': '1.240'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; D12D28 , n =52, 57', 'categories': [{'measurements': [{'value': '1.027', 'groupId': 'OG000', 'lowerLimit': '0.692', 'upperLimit': '1.523'}, {'value': '1.198', 'groupId': 'OG001', 'lowerLimit': '0.811', 'upperLimit': '1.769'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12 , n =54, 59', 'categories': [{'measurements': [{'value': '1.100', 'groupId': 'OG000', 'lowerLimit': '0.705', 'upperLimit': '1.716'}, {'value': '1.043', 'groupId': 'OG001', 'lowerLimit': '0.673', 'upperLimit': '1.617'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28 , n=55, 58', 'categories': [{'measurements': [{'value': '1.504', 'groupId': 'OG000', 'lowerLimit': '1.011', 'upperLimit': '2.237'}, {'value': '1.044', 'groupId': 'OG001', 'lowerLimit': '0.728', 'upperLimit': '1.497'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; D12D28 , n =52, 57', 'categories': [{'measurements': [{'value': '1.289', 'groupId': 'OG000', 'lowerLimit': '0.953', 'upperLimit': '1.745'}, {'value': '1.126', 'groupId': 'OG001', 'lowerLimit': '0.773', 'upperLimit': '1.641'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12 , n =53, 58', 'categories': [{'measurements': [{'value': '0.781', 'groupId': 'OG000', 'lowerLimit': '0.522', 'upperLimit': '1.167'}, {'value': '0.738', 'groupId': 'OG001', 'lowerLimit': '0.491', 'upperLimit': '1.109'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28 , n=54, 58', 'categories': [{'measurements': [{'value': '0.949', 'groupId': 'OG000', 'lowerLimit': '0.637', 'upperLimit': '1.414'}, {'value': '0.818', 'groupId': 'OG001', 'lowerLimit': '0.546', 'upperLimit': '1.227'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; D12D28 , n =51, 56', 'categories': [{'measurements': [{'value': '1.051', 'groupId': 'OG000', 'lowerLimit': '0.818', 'upperLimit': '1.350'}, {'value': '1.012', 'groupId': 'OG001', 'lowerLimit': '0.700', 'upperLimit': '1.465'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.934', 'groupId': 'OG000', 'lowerLimit': '0.656', 'upperLimit': '1.329'}, {'value': '0.960', 'groupId': 'OG001', 'lowerLimit': '0.735', 'upperLimit': '1.255'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.940', 'groupId': 'OG000', 'lowerLimit': '0.629', 'upperLimit': '1.404'}, {'value': '0.887', 'groupId': 'OG001', 'lowerLimit': '0.643', 'upperLimit': '1.222'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '0.869', 'groupId': 'OG000', 'lowerLimit': '0.617', 'upperLimit': '1.223'}, {'value': '1.127', 'groupId': 'OG001', 'lowerLimit': '0.834', 'upperLimit': '1.52'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Lower; SCRD12 ,n =54, 59', 'categories': [{'measurements': [{'value': '0.845', 'groupId': 'OG000', 'lowerLimit': '0.543', 'upperLimit': '1.314'}, {'value': '0.821', 'groupId': 'OG001', 'lowerLimit': '0.531', 'upperLimit': '1.270'}]}]}, {'title': 'FRC; Scan Trimmed; Region; Lower; SCRD28 ,n=55, 58', 'categories': [{'measurements': [{'value': '1.215', 'groupId': 'OG000', 'lowerLimit': '0.835', 'upperLimit': '1.766'}, {'value': '0.868', 'groupId': 'OG001', 'lowerLimit': '0.606', 'upperLimit': '1.243'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Lower; D12D28 ,n =52, 57', 'categories': [{'measurements': [{'value': '1.113', 'groupId': 'OG000', 'lowerLimit': '0.887', 'upperLimit': '1.396'}, {'value': '1.193', 'groupId': 'OG001', 'lowerLimit': '0.805', 'upperLimit': '1.766'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Central; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '1.104', 'groupId': 'OG000', 'lowerLimit': '0.832', 'upperLimit': '1.464'}, {'value': '0.933', 'groupId': 'OG001', 'lowerLimit': '0.769', 'upperLimit': '1.133'}]}]}, {'title': 'FRC;Scan Trimmed; Region Central; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '1.079', 'groupId': 'OG000', 'lowerLimit': '0.794', 'upperLimit': '1.465'}, {'value': '0.950', 'groupId': 'OG001', 'lowerLimit': '0.810', 'upperLimit': '1.114'}]}]}, {'title': 'FRC;Scan Trimmed;Region Central; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.033', 'groupId': 'OG000', 'lowerLimit': '0.851', 'upperLimit': '1.253'}, {'value': '1.010', 'groupId': 'OG001', 'lowerLimit': '0.854', 'upperLimit': '1.195'}]}]}, {'title': 'FRC;Scan Trimmed; Region;Distal; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.800', 'groupId': 'OG000', 'lowerLimit': '0.546', 'upperLimit': '1.174'}, {'value': '0.859', 'groupId': 'OG001', 'lowerLimit': '0.600', 'upperLimit': '1.230'}]}]}, {'title': 'FRC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.993', 'groupId': 'OG000', 'lowerLimit': '0.675', 'upperLimit': '1.459'}, {'value': '0.873', 'groupId': 'OG001', 'lowerLimit': '0.636', 'upperLimit': '1.199'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Distal; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '0.887', 'groupId': 'OG000', 'lowerLimit': '0.670', 'upperLimit': '1.175'}, {'value': '1.220', 'groupId': 'OG001', 'lowerLimit': '0.890', 'upperLimit': '1.674'}]}]}, {'title': 'FRC;Scan Trimmed; Region;Total; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '1.006', 'groupId': 'OG000', 'lowerLimit': '0.760', 'upperLimit': '1.333'}, {'value': '0.919', 'groupId': 'OG001', 'lowerLimit': '0.738', 'upperLimit': '1.145'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Total; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '1.036', 'groupId': 'OG000', 'lowerLimit': '0.758', 'upperLimit': '1.417'}, {'value': '0.922', 'groupId': 'OG001', 'lowerLimit': '0.750', 'upperLimit': '1.132'}]}]}, {'title': 'FRC; Scan Trimmed;Region;Total; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.000', 'groupId': 'OG000', 'lowerLimit': '0.820', 'upperLimit': '1.220'}, {'value': '1.066', 'groupId': 'OG001', 'lowerLimit': '0.875', 'upperLimit': '1.298'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.843', 'groupId': 'OG000', 'lowerLimit': '0.677', 'upperLimit': '1.049'}, {'value': '0.978', 'groupId': 'OG001', 'lowerLimit': '0.810', 'upperLimit': '1.181'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.929', 'groupId': 'OG000', 'lowerLimit': '0.714', 'upperLimit': '1.210'}, {'value': '1.019', 'groupId': 'OG001', 'lowerLimit': '0.826', 'upperLimit': '1.258'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.152', 'groupId': 'OG000', 'lowerLimit': '0.953', 'upperLimit': '1.391'}, {'value': '0.901', 'groupId': 'OG001', 'lowerLimit': '0.759', 'upperLimit': '1.069'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.879', 'groupId': 'OG000', 'lowerLimit': '0.717', 'upperLimit': '1.077'}, {'value': '0.979', 'groupId': 'OG001', 'lowerLimit': '0.829', 'upperLimit': '1.156'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.922', 'groupId': 'OG000', 'lowerLimit': '0.726', 'upperLimit': '1.173'}, {'value': '0.886', 'groupId': 'OG001', 'lowerLimit': '0.687', 'upperLimit': '1.141'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.025', 'groupId': 'OG000', 'lowerLimit': '0.857', 'upperLimit': '1.226'}, {'value': '0.894', 'groupId': 'OG001', 'lowerLimit': '0.750', 'upperLimit': '1.066'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD12 , n =57, 58', 'categories': [{'measurements': [{'value': '1.076', 'groupId': 'OG000', 'lowerLimit': '0.834', 'upperLimit': '1.388'}, {'value': '1.349', 'groupId': 'OG001', 'lowerLimit': '1.001', 'upperLimit': '1.816'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '0.989', 'groupId': 'OG000', 'lowerLimit': '0.722', 'upperLimit': '1.355'}, {'value': '1.220', 'groupId': 'OG001', 'lowerLimit': '0.909', 'upperLimit': '1.637'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; D12D28 , n =56, 58', 'categories': [{'measurements': [{'value': '1.102', 'groupId': 'OG000', 'lowerLimit': '0.869', 'upperLimit': '1.397'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.771', 'upperLimit': '1.266'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.848', 'groupId': 'OG000', 'lowerLimit': '0.587', 'upperLimit': '1.225'}, {'value': '1.143', 'groupId': 'OG001', 'lowerLimit': '0.900', 'upperLimit': '1.451'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.965', 'groupId': 'OG000', 'lowerLimit': '0.688', 'upperLimit': '1.352'}, {'value': '1.122', 'groupId': 'OG001', 'lowerLimit': '0.868', 'upperLimit': '1.452'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.208', 'groupId': 'OG000', 'lowerLimit': '0.941', 'upperLimit': '1.550'}, {'value': '0.927', 'groupId': 'OG001', 'lowerLimit': '0.775', 'upperLimit': '1.109'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12 , n =55, 59', 'categories': [{'measurements': [{'value': '0.813', 'groupId': 'OG000', 'lowerLimit': '0.605', 'upperLimit': '1.093'}, {'value': '1.139', 'groupId': 'OG001', 'lowerLimit': '0.893', 'upperLimit': '1.453'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28 , n=55, 58', 'categories': [{'measurements': [{'value': '0.958', 'groupId': 'OG000', 'lowerLimit': '0.682', 'upperLimit': '1.346'}, {'value': '0.987', 'groupId': 'OG001', 'lowerLimit': '0.758', 'upperLimit': '1.285'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; D12D28 , n=52, 57', 'categories': [{'measurements': [{'value': '1.313', 'groupId': 'OG000', 'lowerLimit': '1.022', 'upperLimit': '1.686'}, {'value': '0.829', 'groupId': 'OG001', 'lowerLimit': '0.670', 'upperLimit': '1.026'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.913', 'groupId': 'OG000', 'lowerLimit': '0.754', 'upperLimit': '1.106'}, {'value': '1.103', 'groupId': 'OG001', 'lowerLimit': '0.911', 'upperLimit': '1.335'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.958', 'groupId': 'OG000', 'lowerLimit': '0.751', 'upperLimit': '1.222'}, {'value': '0.957', 'groupId': 'OG001', 'lowerLimit': '0.764', 'upperLimit': '1.200'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.067', 'groupId': 'OG000', 'lowerLimit': '0.896', 'upperLimit': '1.270'}, {'value': '0.885', 'groupId': 'OG001', 'lowerLimit': '0.752', 'upperLimit': '1.040'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.850', 'groupId': 'OG000', 'lowerLimit': '0.621', 'upperLimit': '1.163'}, {'value': '1.116', 'groupId': 'OG001', 'lowerLimit': '0.897', 'upperLimit': '1.388'}]}]}, {'title': 'TLC; Scan Trimmed; Region; Lower; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.953', 'groupId': 'OG000', 'lowerLimit': '0.676', 'upperLimit': '1.344'}, {'value': '1.056', 'groupId': 'OG001', 'lowerLimit': '0.827', 'upperLimit': '1.347'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.269', 'groupId': 'OG000', 'lowerLimit': '1.021', 'upperLimit': '1.578'}, {'value': '0.862', 'groupId': 'OG001', 'lowerLimit': '0.723', 'upperLimit': '1.028'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Central; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.960', 'groupId': 'OG000', 'lowerLimit': '0.841', 'upperLimit': '1.095'}, {'value': '1.007', 'groupId': 'OG001', 'lowerLimit': '0.937', 'upperLimit': '1.081'}]}]}, {'title': 'TLC;Scan Trimmed; Region Central; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.976', 'groupId': 'OG000', 'lowerLimit': '0.838', 'upperLimit': '1.136'}, {'value': '1.000', 'groupId': 'OG001', 'lowerLimit': '0.933', 'upperLimit': '1.070'}]}]}, {'title': 'TLC;Scan Trimmed;Region Central; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.039', 'groupId': 'OG000', 'lowerLimit': '0.945', 'upperLimit': '1.142'}, {'value': '0.981', 'groupId': 'OG001', 'lowerLimit': '0.932', 'upperLimit': '1.032'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Distal; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.889', 'groupId': 'OG000', 'lowerLimit': '0.680', 'upperLimit': '1.161'}, {'value': '1.116', 'groupId': 'OG001', 'lowerLimit': '0.913', 'upperLimit': '1.364'}]}]}, {'title': 'TLC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.945', 'groupId': 'OG000', 'lowerLimit': '0.698', 'upperLimit': '1.279'}, {'value': '0.976', 'groupId': 'OG001', 'lowerLimit': '0.793', 'upperLimit': '1.201'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Distal; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.189', 'groupId': 'OG000', 'lowerLimit': '1.000', 'upperLimit': '1.414'}, {'value': '0.838', 'groupId': 'OG001', 'lowerLimit': '0.719', 'upperLimit': '0.976'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Total; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.891', 'groupId': 'OG000', 'lowerLimit': '0.762', 'upperLimit': '1.042'}, {'value': '1.061', 'groupId': 'OG001', 'lowerLimit': '0.937', 'upperLimit': '1.202'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Total; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.956', 'groupId': 'OG000', 'lowerLimit': '0.781', 'upperLimit': '1.171'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.861', 'upperLimit': '1.136'}]}]}, {'title': 'TLC; Scan Trimmed;Region;Total; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.133', 'groupId': 'OG000', 'lowerLimit': '0.990', 'upperLimit': '1.296'}, {'value': '0.904', 'groupId': 'OG001', 'lowerLimit': '0.816', 'upperLimit': '1.002'}]}]}], 'analyses': [{'pValue': '60.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.66', 'ciUpperLimit': '1.39', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '51.75', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.65', 'ciUpperLimit': '1.53', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '65.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.60', 'ciUpperLimit': '1.40', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.59', 'ciUpperLimit': '1.21', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '89.98', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.77', 'ciLowerLimit': '0.51', 'ciUpperLimit': '1.15', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '43.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.70', 'ciUpperLimit': '1.51', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '36.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.10', 'ciLowerLimit': '0.64', 'ciUpperLimit': '1.91', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.74', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.70', 'ciLowerLimit': '0.47', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '50.74', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.67', 'ciUpperLimit': '1.48', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '72.81', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.51', 'ciUpperLimit': '1.44', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.41', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.73', 'ciLowerLimit': '0.50', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.07', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.83', 'ciLowerLimit': '0.55', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '69.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.87', 'ciLowerLimit': '0.50', 'ciUpperLimit': '1.51', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '73.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.54', 'ciUpperLimit': '1.37', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.87', 'ciLowerLimit': '0.59', 'ciUpperLimit': '1.29', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '54.22', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.69', 'ciUpperLimit': '1.39', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.46', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.63', 'ciUpperLimit': '1.35', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '21.45', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.16', 'ciLowerLimit': '0.79', 'ciUpperLimit': '1.71', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Upper; D12D28 . The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '69.91', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.50', 'ciUpperLimit': '1.50', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.57', 'ciUpperLimit': '1.31', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '44.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.68', 'ciUpperLimit': '1.58', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.93', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.82', 'ciLowerLimit': '0.65', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region; Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.11', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.77', 'ciLowerLimit': '0.59', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '85.41', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.70', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '54.73', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.62', 'ciUpperLimit': '1.53', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '72.31', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.61', 'ciUpperLimit': '1.30', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '15.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.21', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.75', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '84.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.88', 'ciLowerLimit': '0.68', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '92.24', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.82', 'ciLowerLimit': '0.63', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.42', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.22', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.17', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.46', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.40', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.74', 'ciUpperLimit': '1.22', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '97.39', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.78', 'ciLowerLimit': '0.60', 'ciUpperLimit': '1.00', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '16.02', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.42', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.69', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.90', 'ciLowerLimit': '0.68', 'ciUpperLimit': '1.21', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '90.22', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.69', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.64', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.21', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.62', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '20.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.15', 'ciLowerLimit': '0.82', 'ciUpperLimit': '1.61', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '55.06', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.73', 'ciUpperLimit': '1.31', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '5.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.36', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.97', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '28.82', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.11', 'ciLowerLimit': '0.77', 'ciUpperLimit': '1.60', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '93.00', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.81', 'ciLowerLimit': '0.61', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '1.64', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.42', 'ciLowerLimit': '1.03', 'ciUpperLimit': '1.95', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '50.71', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.72', 'ciUpperLimit': '1.38', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.52', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.68', 'ciLowerLimit': '0.51', 'ciUpperLimit': '0.91', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '3.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.51', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.39', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.71', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '93.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.68', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '3.79', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.33', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.82', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '36.75', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.76', 'ciUpperLimit': '1.48', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.32', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.72', 'ciLowerLimit': '0.56', 'ciUpperLimit': '0.93', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '18.91', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.06', 'ciLowerLimit': '0.93', 'ciUpperLimit': '1.20', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '47.35', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.15', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '78.00', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.96', 'ciLowerLimit': '0.86', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '2.65', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.29', 'ciLowerLimit': '1.00', 'ciUpperLimit': '1.67', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '58.48', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.73', 'ciUpperLimit': '1.29', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.64', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.75', 'ciLowerLimit': '0.61', 'ciUpperLimit': '0.92', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.No'}, {'pValue': '1.90', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.19', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.40', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.03', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.97', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.16', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.19', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.83', 'ciLowerLimit': '0.72', 'ciUpperLimit': '0.97', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'GEOMETRIC_MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'iRaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).', 'unitOfMeasure': 'Kilopascal (Kpa)*s/L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Imaging Specific Airways Resistance: siRaw Measured at FRC and TLC Scan Conditions, Presented in Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12 , n =54, 57', 'categories': [{'measurements': [{'value': '0.896', 'groupId': 'OG000', 'lowerLimit': '0.613', 'upperLimit': '1.310'}, {'value': '0.908', 'groupId': 'OG001', 'lowerLimit': '0.669', 'upperLimit': '1.231'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 56', 'categories': [{'measurements': [{'value': '0.829', 'groupId': 'OG000', 'lowerLimit': '0.516', 'upperLimit': '1.333'}, {'value': '1.013', 'groupId': 'OG001', 'lowerLimit': '0.757', 'upperLimit': '1.355'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RUL; D12D28 , n =51, 55', 'categories': [{'measurements': [{'value': '1.035', 'groupId': 'OG000', 'lowerLimit': '0.712', 'upperLimit': '1.505'}, {'value': '0.926', 'groupId': 'OG001', 'lowerLimit': '0.720', 'upperLimit': '1.191'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.957', 'groupId': 'OG000', 'lowerLimit': '0.671', 'upperLimit': '1.365'}, {'value': '0.944', 'groupId': 'OG001', 'lowerLimit': '0.715', 'upperLimit': '1.247'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.919', 'groupId': 'OG000', 'lowerLimit': '0.610', 'upperLimit': '1.383'}, {'value': '0.834', 'groupId': 'OG001', 'lowerLimit': '0.585', 'upperLimit': '1.189'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '0.849', 'groupId': 'OG000', 'lowerLimit': '0.608', 'upperLimit': '1.184'}, {'value': '0.948', 'groupId': 'OG001', 'lowerLimit': '0.717', 'upperLimit': '1.254'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; SCRD12 , n =52, 58', 'categories': [{'measurements': [{'value': '1.009', 'groupId': 'OG000', 'lowerLimit': '0.655', 'upperLimit': '1.553'}, {'value': '1.013', 'groupId': 'OG001', 'lowerLimit': '0.669', 'upperLimit': '1.533'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; SCRD28 , n=53, 57', 'categories': [{'measurements': [{'value': '1.349', 'groupId': 'OG000', 'lowerLimit': '0.856', 'upperLimit': '2.125'}, {'value': '0.904', 'groupId': 'OG001', 'lowerLimit': '0.649', 'upperLimit': '1.261'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RML; D12D28 , n =52, 56', 'categories': [{'measurements': [{'value': '1.028', 'groupId': 'OG000', 'lowerLimit': '0.695', 'upperLimit': '1.521'}, {'value': '1.213', 'groupId': 'OG001', 'lowerLimit': '0.818', 'upperLimit': '1.798'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12 , n =54, 59', 'categories': [{'measurements': [{'value': '1.078', 'groupId': 'OG000', 'lowerLimit': '0.687', 'upperLimit': '1.691'}, {'value': '1.046', 'groupId': 'OG001', 'lowerLimit': '0.671', 'upperLimit': '1.632'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28 , n=55, 58', 'categories': [{'measurements': [{'value': '1.468', 'groupId': 'OG000', 'lowerLimit': '0.990', 'upperLimit': '2.177'}, {'value': '1.053', 'groupId': 'OG001', 'lowerLimit': '0.736', 'upperLimit': '1.507'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; RLL; D12D28 , n =52, 57', 'categories': [{'measurements': [{'value': '1.284', 'groupId': 'OG000', 'lowerLimit': '0.940', 'upperLimit': '1.754'}, {'value': '1.130', 'groupId': 'OG001', 'lowerLimit': '0.778', 'upperLimit': '1.641'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12 , n =53, 58', 'categories': [{'measurements': [{'value': '0.755', 'groupId': 'OG000', 'lowerLimit': '0.506', 'upperLimit': '1.127'}, {'value': '0.725', 'groupId': 'OG001', 'lowerLimit': '0.479', 'upperLimit': '1.098'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28 , n=54, 58', 'categories': [{'measurements': [{'value': '0.930', 'groupId': 'OG000', 'lowerLimit': '0.629', 'upperLimit': '1.375'}, {'value': '0.811', 'groupId': 'OG001', 'lowerLimit': '0.539', 'upperLimit': '1.220'}]}]}, {'title': 'FRC; Scan Trimmed; Lobes; LLL; D12D28 , n =51, 56', 'categories': [{'measurements': [{'value': '1.063', 'groupId': 'OG000', 'lowerLimit': '0.829', 'upperLimit': '1.362'}, {'value': '1.017', 'groupId': 'OG001', 'lowerLimit': '0.702', 'upperLimit': '1.476'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.915', 'groupId': 'OG000', 'lowerLimit': '0.645', 'upperLimit': '1.300'}, {'value': '0.956', 'groupId': 'OG001', 'lowerLimit': '0.740', 'upperLimit': '1.237'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.919', 'groupId': 'OG000', 'lowerLimit': '0.617', 'upperLimit': '1.370'}, {'value': '0.898', 'groupId': 'OG001', 'lowerLimit': '0.659', 'upperLimit': '1.223'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Upper; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '0.870', 'groupId': 'OG000', 'lowerLimit': '0.620', 'upperLimit': '1.220'}, {'value': '1.142', 'groupId': 'OG001', 'lowerLimit': '0.849', 'upperLimit': '1.536'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Lower; SCRD12 ,n =54, 59', 'categories': [{'measurements': [{'value': '0.825', 'groupId': 'OG000', 'lowerLimit': '0.530', 'upperLimit': '1.283'}, {'value': '0.816', 'groupId': 'OG001', 'lowerLimit': '0.524', 'upperLimit': '1.270'}]}]}, {'title': 'FRC; Scan Trimmed; Region; Lower; SCRD28 ,n=55, 58', 'categories': [{'measurements': [{'value': '1.188', 'groupId': 'OG000', 'lowerLimit': '0.821', 'upperLimit': '1.718'}, {'value': '0.869', 'groupId': 'OG001', 'lowerLimit': '0.606', 'upperLimit': '1.246'}]}]}, {'title': 'FRC; Scan Trimmed; Region;Lower; D12D28 ,n =52, 57', 'categories': [{'measurements': [{'value': '1.114', 'groupId': 'OG000', 'lowerLimit': '0.881', 'upperLimit': '1.409'}, {'value': '1.200', 'groupId': 'OG001', 'lowerLimit': '0.810', 'upperLimit': '1.777'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Central; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '1.077', 'groupId': 'OG000', 'lowerLimit': '0.813', 'upperLimit': '1.425'}, {'value': '0.928', 'groupId': 'OG001', 'lowerLimit': '0.762', 'upperLimit': '1.130'}]}]}, {'title': 'FRC;Scan Trimmed; Region Central; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '1.053', 'groupId': 'OG000', 'lowerLimit': '0.777', 'upperLimit': '1.427'}, {'value': '0.957', 'groupId': 'OG001', 'lowerLimit': '0.817', 'upperLimit': '1.121'}]}]}, {'title': 'FRC;Scan Trimmed;Region Central; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.035', 'groupId': 'OG000', 'lowerLimit': '0.851', 'upperLimit': '1.259'}, {'value': '1.022', 'groupId': 'OG001', 'lowerLimit': '0.863', 'upperLimit': '1.210'}]}]}, {'title': 'FRC;Scan Trimmed; Region;Distal; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.781', 'groupId': 'OG000', 'lowerLimit': '0.533', 'upperLimit': '1.144'}, {'value': '0.854', 'groupId': 'OG001', 'lowerLimit': '0.598', 'upperLimit': '1.220'}]}]}, {'title': 'FRC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.969', 'groupId': 'OG000', 'lowerLimit': '0.661', 'upperLimit': '1.421'}, {'value': '0.880', 'groupId': 'OG001', 'lowerLimit': '0.645', 'upperLimit': '1.202'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Distal; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '0.890', 'groupId': 'OG000', 'lowerLimit': '0.672', 'upperLimit': '1.179'}, {'value': '1.234', 'groupId': 'OG001', 'lowerLimit': '0.903', 'upperLimit': '1.687'}]}]}, {'title': 'FRC;Scan Trimmed; Region;Total; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.982', 'groupId': 'OG000', 'lowerLimit': '0.741', 'upperLimit': '1.300'}, {'value': '0.914', 'groupId': 'OG001', 'lowerLimit': '0.732', 'upperLimit': '1.140'}]}]}, {'title': 'FRC;Scan Trimmed;Region;Total; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '1.012', 'groupId': 'OG000', 'lowerLimit': '0.742', 'upperLimit': '1.378'}, {'value': '0.929', 'groupId': 'OG001', 'lowerLimit': '0.760', 'upperLimit': '1.136'}]}]}, {'title': 'FRC; Scan Trimmed;Region;Total; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.003', 'groupId': 'OG000', 'lowerLimit': '0.821', 'upperLimit': '1.225'}, {'value': '1.078', 'groupId': 'OG001', 'lowerLimit': '0.886', 'upperLimit': '1.311'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.848', 'groupId': 'OG000', 'lowerLimit': '0.686', 'upperLimit': '1.049'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.816', 'upperLimit': '1.198'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.934', 'groupId': 'OG000', 'lowerLimit': '0.725', 'upperLimit': '1.203'}, {'value': '1.043', 'groupId': 'OG001', 'lowerLimit': '0.846', 'upperLimit': '1.285'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.142', 'groupId': 'OG000', 'lowerLimit': '0.945', 'upperLimit': '1.379'}, {'value': '0.903', 'groupId': 'OG001', 'lowerLimit': '0.757', 'upperLimit': '1.077'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.880', 'groupId': 'OG000', 'lowerLimit': '0.721', 'upperLimit': '1.074'}, {'value': '0.977', 'groupId': 'OG001', 'lowerLimit': '0.832', 'upperLimit': '1.148'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.926', 'groupId': 'OG000', 'lowerLimit': '0.736', 'upperLimit': '1.165'}, {'value': '0.885', 'groupId': 'OG001', 'lowerLimit': '0.690', 'upperLimit': '1.134'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LUL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.023', 'groupId': 'OG000', 'lowerLimit': '0.856', 'upperLimit': '1.221'}, {'value': '0.896', 'groupId': 'OG001', 'lowerLimit': '0.751', 'upperLimit': '1.069'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD12 , n =57, 58', 'categories': [{'measurements': [{'value': '1.073', 'groupId': 'OG000', 'lowerLimit': '0.829', 'upperLimit': '1.390'}, {'value': '1.343', 'groupId': 'OG001', 'lowerLimit': '0.995', 'upperLimit': '1.814'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; SCRD28 , n=56, 59', 'categories': [{'measurements': [{'value': '0.981', 'groupId': 'OG000', 'lowerLimit': '0.727', 'upperLimit': '1.324'}, {'value': '1.238', 'groupId': 'OG001', 'lowerLimit': '0.921', 'upperLimit': '1.664'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RML; D12D28 , n =56, 58', 'categories': [{'measurements': [{'value': '1.093', 'groupId': 'OG000', 'lowerLimit': '0.867', 'upperLimit': '1.377'}, {'value': '1.010', 'groupId': 'OG001', 'lowerLimit': '0.782', 'upperLimit': '1.303'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.854', 'groupId': 'OG000', 'lowerLimit': '0.595', 'upperLimit': '1.226'}, {'value': '1.149', 'groupId': 'OG001', 'lowerLimit': '0.910', 'upperLimit': '1.449'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.964', 'groupId': 'OG000', 'lowerLimit': '0.695', 'upperLimit': '1.337'}, {'value': '1.134', 'groupId': 'OG001', 'lowerLimit': '0.887', 'upperLimit': '1.450'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; RLL; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.192', 'groupId': 'OG000', 'lowerLimit': '0.937', 'upperLimit': '1.518'}, {'value': '0.935', 'groupId': 'OG001', 'lowerLimit': '0.782', 'upperLimit': '1.117'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12 , n =55, 59', 'categories': [{'measurements': [{'value': '0.820', 'groupId': 'OG000', 'lowerLimit': '0.617', 'upperLimit': '1.089'}, {'value': '1.126', 'groupId': 'OG001', 'lowerLimit': '0.891', 'upperLimit': '1.424'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28 , n=55, 58', 'categories': [{'measurements': [{'value': '0.960', 'groupId': 'OG000', 'lowerLimit': '0.690', 'upperLimit': '1.335'}, {'value': '0.985', 'groupId': 'OG001', 'lowerLimit': '0.760', 'upperLimit': '1.276'}]}]}, {'title': 'TLC; Scan Trimmed; Lobes; LLL; D12D28 , n=52, 57', 'categories': [{'measurements': [{'value': '1.302', 'groupId': 'OG000', 'lowerLimit': '1.013', 'upperLimit': '1.674'}, {'value': '0.839', 'groupId': 'OG001', 'lowerLimit': '0.679', 'upperLimit': '1.037'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.917', 'groupId': 'OG000', 'lowerLimit': '0.760', 'upperLimit': '1.106'}, {'value': '1.100', 'groupId': 'OG001', 'lowerLimit': '0.912', 'upperLimit': '1.327'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.961', 'groupId': 'OG000', 'lowerLimit': '0.762', 'upperLimit': '1.213'}, {'value': '0.957', 'groupId': 'OG001', 'lowerLimit': '0.767', 'upperLimit': '1.195'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Upper; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.060', 'groupId': 'OG000', 'lowerLimit': '0.891', 'upperLimit': '1.262'}, {'value': '0.888', 'groupId': 'OG001', 'lowerLimit': '0.755', 'upperLimit': '1.045'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.856', 'groupId': 'OG000', 'lowerLimit': '0.631', 'upperLimit': '1.162'}, {'value': '1.112', 'groupId': 'OG001', 'lowerLimit': '0.900', 'upperLimit': '1.374'}]}]}, {'title': 'TLC; Scan Trimmed; Region; Lower; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.954', 'groupId': 'OG000', 'lowerLimit': '0.683', 'upperLimit': '1.332'}, {'value': '1.061', 'groupId': 'OG001', 'lowerLimit': '0.838', 'upperLimit': '1.342'}]}]}, {'title': 'TLC; Scan Trimmed; Region;Lower; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.256', 'groupId': 'OG000', 'lowerLimit': '1.015', 'upperLimit': '1.553'}, {'value': '0.871', 'groupId': 'OG001', 'lowerLimit': '0.731', 'upperLimit': '1.038'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Central; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.963', 'groupId': 'OG000', 'lowerLimit': '0.850', 'upperLimit': '1.092'}, {'value': '1.004', 'groupId': 'OG001', 'lowerLimit': '0.931', 'upperLimit': '1.083'}]}]}, {'title': 'TLC;Scan Trimmed; Region Central; SCRD28 ,n=56, 58', 'categories': [{'measurements': [{'value': '0.977', 'groupId': 'OG000', 'lowerLimit': '0.852', 'upperLimit': '1.121'}, {'value': '1.002', 'groupId': 'OG001', 'lowerLimit': '0.927', 'upperLimit': '1.082'}]}]}, {'title': 'TLC;Scan Trimmed;Region Central; D12D28 ,n =53, 57', 'categories': [{'measurements': [{'value': '1.032', 'groupId': 'OG000', 'lowerLimit': '0.939', 'upperLimit': '1.135'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.941', 'upperLimit': '1.037'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Distal; SCRD12 ,n =56, 59', 'categories': [{'measurements': [{'value': '0.892', 'groupId': 'OG000', 'lowerLimit': '0.688', 'upperLimit': '1.157'}, {'value': '1.112', 'groupId': 'OG001', 'lowerLimit': '0.915', 'upperLimit': '1.353'}]}]}, {'title': 'TLC;Scan Trimmed;Region; Distal; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.946', 'groupId': 'OG000', 'lowerLimit': '0.705', 'upperLimit': '1.270'}, {'value': '0.978', 'groupId': 'OG001', 'lowerLimit': '0.800', 'upperLimit': '1.195'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Distal; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.181', 'groupId': 'OG000', 'lowerLimit': '0.996', 'upperLimit': '1.401'}, {'value': '0.844', 'groupId': 'OG001', 'lowerLimit': '0.724', 'upperLimit': '0.983'}]}]}, {'title': 'TLC;Scan Trimmed; Region;Total; SCRD12 , n =56, 59', 'categories': [{'measurements': [{'value': '0.895', 'groupId': 'OG000', 'lowerLimit': '0.771', 'upperLimit': '1.038'}, {'value': '1.058', 'groupId': 'OG001', 'lowerLimit': '0.938', 'upperLimit': '1.194'}]}]}, {'title': 'TLC;Scan Trimmed;Region;Total; SCRD28 , n=56, 58', 'categories': [{'measurements': [{'value': '0.958', 'groupId': 'OG000', 'lowerLimit': '0.793', 'upperLimit': '1.158'}, {'value': '0.991', 'groupId': 'OG001', 'lowerLimit': '0.867', 'upperLimit': '1.133'}]}]}, {'title': 'TLC; Scan Trimmed;Region;Total; D12D28 , n =53, 57', 'categories': [{'measurements': [{'value': '1.125', 'groupId': 'OG000', 'lowerLimit': '0.986', 'upperLimit': '1.285'}, {'value': '0.911', 'groupId': 'OG001', 'lowerLimit': '0.822', 'upperLimit': '1.008'}]}]}], 'analyses': [{'pValue': '67.19', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.64', 'ciUpperLimit': '1.33', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '44.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.66', 'ciUpperLimit': '1.61', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '59.90', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.61', 'ciUpperLimit': '1.46', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '70.12', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.91', 'ciLowerLimit': '0.63', 'ciUpperLimit': '1.31', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '83.98', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.82', 'ciLowerLimit': '0.54', 'ciUpperLimit': '1.22', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '34.93', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.08', 'ciLowerLimit': '0.73', 'ciUpperLimit': '1.57', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '32.45', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.14', 'ciLowerLimit': '0.65', 'ciUpperLimit': '1.96', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '95.35', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.70', 'ciLowerLimit': '0.46', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '50.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.66', 'ciUpperLimit': '1.54', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '59.37', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.55', 'ciUpperLimit': '1.60', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.80', 'ciLowerLimit': '0.55', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '70.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.59', 'ciUpperLimit': '1.36', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.71', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.91', 'ciLowerLimit': '0.51', 'ciUpperLimit': '1.60', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '65.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.91', 'ciLowerLimit': '0.57', 'ciUpperLimit': '1.44', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '71.95', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.89', 'ciLowerLimit': '0.60', 'ciUpperLimit': '1.32', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.28', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.71', 'ciUpperLimit': '1.43', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '61.06', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.95', 'ciLowerLimit': '0.65', 'ciUpperLimit': '1.39', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '18.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.19', 'ciLowerLimit': '0.82', 'ciUpperLimit': '1.74', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '61.12', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.53', 'ciUpperLimit': '1.61', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '64.40', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.92', 'ciLowerLimit': '0.61', 'ciUpperLimit': '1.41', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '38.12', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.69', 'ciUpperLimit': '1.66', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '91.00', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.67', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '94.52', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.81', 'ciLowerLimit': '0.62', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '82.11', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.90', 'ciLowerLimit': '0.72', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region Central; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.10', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.64', 'ciUpperLimit': '1.60', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '65.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.64', 'ciUpperLimit': '1.36', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '11.46', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.25', 'ciLowerLimit': '0.87', 'ciUpperLimit': '1.80', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '77.20', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.91', 'ciLowerLimit': '0.70', 'ciUpperLimit': '1.17', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '87.35', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.66', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '56.53', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.77', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures random effect', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '7.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.19', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.50', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '55.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.28', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '96.49', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.79', 'ciLowerLimit': '0.61', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '14.54', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.13', 'ciLowerLimit': '0.90', 'ciUpperLimit': '1.44', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.85', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.94', 'ciLowerLimit': '0.71', 'ciUpperLimit': '1.25', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '85.77', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.88', 'ciLowerLimit': '0.70', 'ciUpperLimit': '1.11', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LUL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '8.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.24', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.70', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '14.80', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.75', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '45.69', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.37', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RML; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '2.94', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.42', 'ciLowerLimit': '0.99', 'ciUpperLimit': '2.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '13.92', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '0.85', 'ciUpperLimit': '1.73', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.40', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.86', 'ciLowerLimit': '0.65', 'ciUpperLimit': '1.13', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; RLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.46', 'ciLowerLimit': '1.06', 'ciUpperLimit': '2.00', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '41.25', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.75', 'ciUpperLimit': '1.43', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.20', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.70', 'ciLowerLimit': '0.52', 'ciUpperLimit': '0.94', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Lobes; LLL; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '3.49', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.22', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.51', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; SCRD12 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '73.09', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.93', 'ciLowerLimit': '0.72', 'ciUpperLimit': '1.19', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '92.41', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.69', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Upper; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '2.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.38', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.89', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '23.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.12', 'ciLowerLimit': '0.81', 'ciUpperLimit': '1.56', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region; Lower; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters.Unstructured covariance matrix fitted, accounting for correlation within region and visit'}, {'pValue': '98.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.75', 'ciLowerLimit': '0.59', 'ciUpperLimit': '0.96', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed; Region;Lower; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '14.50', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.07', 'ciLowerLimit': '0.95', 'ciUpperLimit': '1.20', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Central; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '30.26', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.91', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region Central; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '62.84', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.89', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region Central; D12D28 .The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '2.06', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.31', 'ciLowerLimit': '1.01', 'ciUpperLimit': '1.70', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Distal; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '49.97', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.76', 'ciUpperLimit': '1.32', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region; Distal; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '99.43', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.76', 'ciLowerLimit': '0.62', 'ciUpperLimit': '0.94', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Distal; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '1.17', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.20', 'ciLowerLimit': '1.02', 'ciUpperLimit': '1.41', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed; Region;Total; SCRD12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '49.78', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.84', 'ciUpperLimit': '1.18', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC;Scan Trimmed;Region;Total; SCRD28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '98.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.85', 'ciLowerLimit': '0.73', 'ciUpperLimit': '0.98', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC; Scan Trimmed;Region;Total; D12D28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'GEOMETRIC_MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'siRaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).', 'unitOfMeasure': 'Kpa*s', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Lung Lobar Volumes Measured at FRC and TLC Scan Conditions, Presented in Longitudinal Scan Types, Measured in 5 Lobes and 5 Regions at Day 12 and Day 28', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC Lobes; RUL; Day 12, n =56, 57', 'categories': [{'measurements': [{'value': '0.983', 'groupId': 'OG000', 'lowerLimit': '0.953', 'upperLimit': '1.014'}, {'value': '0.995', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.026'}]}]}, {'title': 'FRC Lobes; RUL Day 28, n =56, 56', 'categories': [{'measurements': [{'value': '0.977', 'groupId': 'OG000', 'lowerLimit': '0.949', 'upperLimit': '1.005'}, {'value': '1.017', 'groupId': 'OG001', 'lowerLimit': '0.985', 'upperLimit': '1.050'}]}]}, {'title': 'FRC Lobes; LUL Day 12, n =56, 59', 'categories': [{'measurements': [{'value': '0.974', 'groupId': 'OG000', 'lowerLimit': '0.943', 'upperLimit': '1.007'}, {'value': '0.998', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.034'}]}]}, {'title': 'FRC Lobes;LUL Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.980', 'groupId': 'OG000', 'lowerLimit': '0.953', 'upperLimit': '1.009'}, {'value': '1.017', 'groupId': 'OG001', 'lowerLimit': '0.978', 'upperLimit': '1.057'}]}]}, {'title': 'FRC Lobes; RML Day 12, n =55, 58', 'categories': [{'measurements': [{'value': '0.981', 'groupId': 'OG000', 'lowerLimit': '0.943', 'upperLimit': '1.022'}, {'value': '0.992', 'groupId': 'OG001', 'lowerLimit': '0.959', 'upperLimit': '1.025'}]}]}, {'title': 'FRC Lobes; RML Day 28, n =56, 57', 'categories': [{'measurements': [{'value': '0.972', 'groupId': 'OG000', 'lowerLimit': '0.943', 'upperLimit': '1.002'}, {'value': '0.996', 'groupId': 'OG001', 'lowerLimit': '0.963', 'upperLimit': '1.030'}]}]}, {'title': 'FRC Lobes; RLL Day 12, n =56, 59', 'categories': [{'measurements': [{'value': '0.977', 'groupId': 'OG000', 'lowerLimit': '0.933', 'upperLimit': '1.024'}, {'value': '1.004', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.045'}]}]}, {'title': 'FRC Lobes; RLL Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.972', 'groupId': 'OG000', 'lowerLimit': '0.939', 'upperLimit': '1.007'}, {'value': '1.009', 'groupId': 'OG001', 'lowerLimit': '0.968', 'upperLimit': '1.051'}]}]}, {'title': 'FRC Lobes; LLL Day 12, n =55, 59', 'categories': [{'measurements': [{'value': '0.968', 'groupId': 'OG000', 'lowerLimit': '0.934', 'upperLimit': '1.004'}, {'value': '0.983', 'groupId': 'OG001', 'lowerLimit': '0.944', 'upperLimit': '1.024'}]}]}, {'title': 'FRC Lobes; LLL Day 28, n =55, 58', 'categories': [{'measurements': [{'value': '0.979', 'groupId': 'OG000', 'lowerLimit': '0.948', 'upperLimit': '1.010'}, {'value': '0.991', 'groupId': 'OG001', 'lowerLimit': '0.950', 'upperLimit': '1.033'}]}]}, {'title': 'FRC Region; Upper Day 12, n =56, 59', 'categories': [{'measurements': [{'value': '0.980', 'groupId': 'OG000', 'lowerLimit': '0.950', 'upperLimit': '1.011'}, {'value': '0.996', 'groupId': 'OG001', 'lowerLimit': '0.966', 'upperLimit': '1.027'}]}]}, {'title': 'FRC Region; Upper Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.978', 'groupId': 'OG000', 'lowerLimit': '0.954', 'upperLimit': '1.004'}, {'value': '1.013', 'groupId': 'OG001', 'lowerLimit': '0.979', 'upperLimit': '1.047'}]}]}, {'title': 'FRC Region; Lower Day 12, n =56, 59', 'categories': [{'measurements': [{'value': '0.975', 'groupId': 'OG000', 'lowerLimit': '0.936', 'upperLimit': '1.016'}, {'value': '0.994', 'groupId': 'OG001', 'lowerLimit': '0.956', 'upperLimit': '1.033'}]}]}, {'title': 'FRC Region; Lower Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.975', 'groupId': 'OG000', 'lowerLimit': '0.945', 'upperLimit': '1.007'}, {'value': '1.001', 'groupId': 'OG001', 'lowerLimit': '0.962', 'upperLimit': '1.041'}]}]}, {'title': 'FRC Region; Total Day 12, n =56, 59', 'categories': [{'measurements': [{'value': '0.975', 'groupId': 'OG000', 'lowerLimit': '0.944', 'upperLimit': '1.007'}, {'value': '0.994', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.026'}]}]}, {'title': 'FRC Region; Total Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.976', 'groupId': 'OG000', 'lowerLimit': '0.950', 'upperLimit': '1.003'}, {'value': '1.008', 'groupId': 'OG001', 'lowerLimit': '0.974', 'upperLimit': '1.042'}]}]}, {'title': 'TLC Lobes; RUL; Day 12, n =58, 57', 'categories': [{'measurements': [{'value': '1.009', 'groupId': 'OG000', 'lowerLimit': '0.994', 'upperLimit': '1.024'}, {'value': '0.999', 'groupId': 'OG001', 'lowerLimit': '0.986', 'upperLimit': '1.011'}]}]}, {'title': 'TLC Lobes; RUL Day 28, n =56, 57', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.985', 'upperLimit': '1.025'}, {'value': '0.999', 'groupId': 'OG001', 'lowerLimit': '0.984', 'upperLimit': '1.013'}]}]}, {'title': 'TLC Lobes; LUL Day 12, n =58, 59', 'categories': [{'measurements': [{'value': '1.002', 'groupId': 'OG000', 'lowerLimit': '0.989', 'upperLimit': '1.014'}, {'value': '0.998', 'groupId': 'OG001', 'lowerLimit': '0.984', 'upperLimit': '1.013'}]}]}, {'title': 'TLC Lobes;LUL Day 28, n =56, 59', 'categories': [{'measurements': [{'value': '1.004', 'groupId': 'OG000', 'lowerLimit': '0.984', 'upperLimit': '1.025'}, {'value': '0.998', 'groupId': 'OG001', 'lowerLimit': '0.982', 'upperLimit': '1.014'}]}]}, {'title': 'TLC Lobes; RML Day 12, n =57, 58', 'categories': [{'measurements': [{'value': '0.998', 'groupId': 'OG000', 'lowerLimit': '0.975', 'upperLimit': '1.021'}, {'value': '0.988', 'groupId': 'OG001', 'lowerLimit': '0.970', 'upperLimit': '1.005'}]}]}, {'title': 'TLC Lobes; RML Day 28, n =56, 58', 'categories': [{'measurements': [{'value': '0.992', 'groupId': 'OG000', 'lowerLimit': '0.960', 'upperLimit': '1.025'}, {'value': '0.996', 'groupId': 'OG001', 'lowerLimit': '0.979', 'upperLimit': '1.013'}]}]}, {'title': 'TLC Lobes; RLL Day 12, n =58, 59', 'categories': [{'measurements': [{'value': '1.010', 'groupId': 'OG000', 'lowerLimit': '0.983', 'upperLimit': '1.038'}, {'value': '1.005', 'groupId': 'OG001', 'lowerLimit': '0.977', 'upperLimit': '1.034'}]}]}, {'title': 'TLC Lobes; RLL Day 28, n =56, 59', 'categories': [{'measurements': [{'value': '1.000', 'groupId': 'OG000', 'lowerLimit': '0.974', 'upperLimit': '1.026'}, {'value': '1.009', 'groupId': 'OG001', 'lowerLimit': '0.975', 'upperLimit': '1.044'}]}]}, {'title': 'TLC Lobes; LLL Day 12, n =57, 59', 'categories': [{'measurements': [{'value': '1.008', 'groupId': 'OG000', 'lowerLimit': '0.975', 'upperLimit': '1.042'}, {'value': '0.989', 'groupId': 'OG001', 'lowerLimit': '0.964', 'upperLimit': '1.014'}]}]}, {'title': 'TLC Lobes; LLL Day 28, n =55, 59', 'categories': [{'measurements': [{'value': '1.002', 'groupId': 'OG000', 'lowerLimit': '0.977', 'upperLimit': '1.028'}, {'value': '0.996', 'groupId': 'OG001', 'lowerLimit': '0.968', 'upperLimit': '1.024'}]}]}, {'title': 'TLC Upper Day 12, n =58, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.993', 'upperLimit': '1.017'}, {'value': '0.997', 'groupId': 'OG001', 'lowerLimit': '0.985', 'upperLimit': '1.010'}]}]}, {'title': 'TLC UpperDay 28, n =56, 59', 'categories': [{'measurements': [{'value': '1.004', 'groupId': 'OG000', 'lowerLimit': '0.984', 'upperLimit': '1.023'}, {'value': '0.999', 'groupId': 'OG001', 'lowerLimit': '0.985', 'upperLimit': '1.012'}]}]}, {'title': 'TLC Lower Day 12, n =58, 59', 'categories': [{'measurements': [{'value': '1.009', 'groupId': 'OG000', 'lowerLimit': '0.982', 'upperLimit': '1.037'}, {'value': '0.997', 'groupId': 'OG001', 'lowerLimit': '0.972', 'upperLimit': '1.023'}]}]}, {'title': 'TLC Lower Day 28, n =56, 59', 'categories': [{'measurements': [{'value': '1.000', 'groupId': 'OG000', 'lowerLimit': '0.978', 'upperLimit': '1.024'}, {'value': '1.003', 'groupId': 'OG001', 'lowerLimit': '0.973', 'upperLimit': '1.034'}]}]}, {'title': 'TLC Total Day 12, n =58, 59', 'categories': [{'measurements': [{'value': '1.005', 'groupId': 'OG000', 'lowerLimit': '0.989', 'upperLimit': '1.022'}, {'value': '0.997', 'groupId': 'OG001', 'lowerLimit': '0.980', 'upperLimit': '1.015'}]}]}, {'title': 'TLC Total Day 28, n =56, 59', 'categories': [{'measurements': [{'value': '1.002', 'groupId': 'OG000', 'lowerLimit': '0.982', 'upperLimit': '1.022'}, {'value': '1.001', 'groupId': 'OG001', 'lowerLimit': '0.981', 'upperLimit': '1.021'}]}]}], 'analyses': [{'pValue': '32.51', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RUL; Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.21', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.08', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RUL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '15.91', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; LUL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '6.73', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.09', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes;LUL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '27.65', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RML Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '12.19', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RML Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '11.62', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RLL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '7.66', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.10', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; RLL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '28.88', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; LLL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '28.28', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Lobes; LLL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '27.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Upper Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '9.83', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Upper Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.No'}, {'pValue': '21.87', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Lower Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '18.58', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Lower Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '22.28', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Total Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '10.86', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.03', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Region; Total Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '84.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RUL; Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.78', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RUL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '69.42', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; LUL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '62.63', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes;LUL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '72.55', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RML Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '36.28', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RML Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '47.44', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RLL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '22.99', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; RLL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '85.95', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.98', 'ciLowerLimit': '0.94', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; LLL Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '60.20', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lobes; LLL Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '81.34', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Upper Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '63.04', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC UpperDay 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '69.67', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.96', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lower Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '39.81', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.04', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Lower Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '73.01', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Total Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '48.97', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Total Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'GEOMETRIC_MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Change from Baseline in lung lobar volumes was measured at functional residual volume (FRC) and total lung capacity (TLC) scan conditions. Data was collected at longitudinal time points: Day 12 \\& Day 28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points the baseline is screening. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).', 'unitOfMeasure': 'L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Imaging Trachea Length and Diameter After 12 Days of Treatment and After 28 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC Length Day 12, n=56, 59', 'categories': [{'measurements': [{'value': '-1.886', 'spread': '7.6043', 'groupId': 'OG000'}, {'value': '0.517', 'spread': '6.0882', 'groupId': 'OG001'}]}]}, {'title': 'FRC Length Day 28, n=56, 58', 'categories': [{'measurements': [{'value': '-1.434', 'spread': '6.7887', 'groupId': 'OG000'}, {'value': '0.485', 'spread': '6.6552', 'groupId': 'OG001'}]}]}, {'title': 'FRC Diameter Day 12, n=56, 59', 'categories': [{'measurements': [{'value': '-0.247', 'spread': '1.8777', 'groupId': 'OG000'}, {'value': '0.059', 'spread': '1.1657', 'groupId': 'OG001'}]}]}, {'title': 'FRC Diameter Day 28, n=56, 58', 'categories': [{'measurements': [{'value': '-0.261', 'spread': '1.8672', 'groupId': 'OG000'}, {'value': '-0.047', 'spread': '1.1522', 'groupId': 'OG001'}]}]}, {'title': 'TLC Length Day 12, n=58, 59', 'categories': [{'measurements': [{'value': '0.295', 'spread': '4.0608', 'groupId': 'OG000'}, {'value': '-0.663', 'spread': '3.8027', 'groupId': 'OG001'}]}]}, {'title': 'TLC Length Day 28, n=56, 59', 'categories': [{'measurements': [{'value': '0.168', 'spread': '4.5501', 'groupId': 'OG000'}, {'value': '-0.495', 'spread': '3.7295', 'groupId': 'OG001'}]}]}, {'title': 'TLC Diameter Day 12, n=58, 59', 'categories': [{'measurements': [{'value': '-0.067', 'spread': '1.0127', 'groupId': 'OG000'}, {'value': '-0.056', 'spread': '0.5098', 'groupId': 'OG001'}]}]}, {'title': 'TLC Diameter Day 28, n=56, 59', 'categories': [{'measurements': [{'value': '-0.046', 'spread': '1.0240', 'groupId': 'OG000'}, {'value': '-0.082', 'spread': '0.5579', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '2.89', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.04', 'ciLowerLimit': '1.00', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Length Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '8.49', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.99', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Length Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '86.21', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.02', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.07', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Diameter Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '75.20', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Diameter Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '84.29', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Length Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '71.08', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Length Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '34.93', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Diameter Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '25.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.01', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is greater than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Diameter Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Imaging trachea length and diameter was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. TLC is the volume in the lungs at maximal inflation and FRC is the volume in the lungs at the end-expiratory position. The Baseline for the assessment on Day 12 and Day 28 is the Screening value. Change from Baseline is the post-Baseline value minus the Baseline value. The change from Baseline data is presented for Day 12 and Day 28 for trachea length and diameter. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'Millimeter (mm)', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Imaging Trachea Length/Diameter After 12 Days of Treatment and After 28 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 µg', 'description': 'Participants received 1000 µg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'FRC Length/Diameter Day 12, n=56', 'categories': [{'measurements': [{'value': '-0.030', 'spread': '0.7717', 'groupId': 'OG000'}, {'value': '0.000', 'spread': '0.5620', 'groupId': 'OG001'}]}]}, {'title': 'FRC Length/Diameter Day 28, n=56', 'categories': [{'measurements': [{'value': '-0.017', 'spread': '0.7469', 'groupId': 'OG000'}, {'value': '0.059', 'spread': '0.5169', 'groupId': 'OG001'}]}]}, {'title': 'TLC Length/Diameter Day 12, n=5', 'categories': [{'measurements': [{'value': '0.024', 'spread': '0.3602', 'groupId': 'OG000'}, {'value': '-0.023', 'spread': '0.2913', 'groupId': 'OG001'}]}]}, {'title': 'TLC Length/Diameter Day 28, n=5', 'categories': [{'measurements': [{'value': '0.004', 'spread': '0.3715', 'groupId': 'OG000'}, {'value': '-0.006', 'spread': '0.2783', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '28.51', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.06', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Length/Diameter Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '32.15', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.01', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.05', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'FRC Length/Diameter Day 28. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '66.51', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.99', 'ciLowerLimit': '0.97', 'ciUpperLimit': '1.02', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Length/Diameter Day 12. The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '45.28', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Posterior Median Ratio', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.00', 'ciLowerLimit': '0.98', 'ciUpperLimit': '1.03', 'pValueComment': 'The data entered for the p-value represents the posterior probability that the true treatment ratio is less than 1. P-value is denoted in percentage.', 'estimateComment': 'TLC Length/Diameter Day 28 The data entered to the 95% confidence interval represents the 95% equi-tailed credible interval.', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Imaging trachea length/diameter was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. TLC is the volume in the lungs at maximal inflation and FRC is the volume in the lungs at the end-expiratory position. The Baseline for the assessment on Day 12 and Day 28 is the Screening value. Change from Baseline is the post-Baseline value minus the Baseline value. The change from Baseline data is presented for Day 12 and Day 28 for trachea length/diameter. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'ratio', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population excluding the subject with a pacemaker.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Adverse Events (AE)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '49', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'From start of IP through the Study Phase (84 days post-dose) (assessed up to follow-up duration of approximately 100 days)', 'description': 'An AE is defined as any untoward medical occurrence in a participant, temporally associated with the use of a medicinal product, whether or not considered related to the medicinal product. Adverse events were collected from the start of study treatment until the follow-up contact.', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All Subjects Population: all randomized participants who received at least one dose of study treatment.'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Abnormal Hematology Parameters', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'High HCT Screening/Day 1, n=63, 62', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HCT Day 12, n=60, 58', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HCT Day 28, n=57, 58', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HCT Day 56, n=55, 52', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HCT Day 84, n=49, 53', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HCT Follow-up/Early Withdraw, n=54, 53', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HB Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HB Day 12, n=60, 58', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HB Day 28, n=57, 58', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HB Day 56, n=55, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HB Day 84, n=49, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HB Follow-up/Early Withdraw, n=54, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Screening/ Day 1, n=62, 60', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Day 12, n=59, 58', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Day 28, n=56, 57', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Day 56, n=54, 52', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Day 84, n=48, 50', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low LC Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High PC Screening/Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High PC Day 12, n=58, 57', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High PC Day 28, n=57, 58', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High PC Day 56, n=55, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High PC Day 84, n=49, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High PC Follow-up/Early Withdraw, n=54, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Day 12, n=58, 57', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Day 28, n=57, 58', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Day 56, n=55, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Day 84, n=49, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low PC Follow-up/Early Withdraw, n=54, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Screening/ Day 1, n=62, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Day 12, n=59, 58', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Day 28, n=56, 57', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Day 56, n=54, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Day 84, n=48, 50', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low TN Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Day 12, n=56, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Day 28, n=56, 57', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Day 56, n=54, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Day 84, n=48, 50', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High WBC Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Day 12, n=56, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Day 28, n=56, 57', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Day 56, n=54, 52', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Day 84, n=48, 50', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low WBC Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 Days)', 'description': 'Hematology parameter included Hematocrit (HCT), Hemoglobin (HB), Lymphocytes (LC), Platelet Count (PC), Total Neutrophils (TN), and White Blood Cell (WBC) count at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, and at follow-up/Early withdrawal. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All Subjects Population'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Abnormal Clinical Chemistry Parameters', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'High ALT Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High ALT Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALT Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALT Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALT Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALT Follow-up/Early Withdraw, n=53, 54', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Albumin Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High ALP Follow-up/Early Withdraw, n=53, 54', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High AST Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High AST Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High AST Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High AST Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High AST Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High AST Follow-up/Early Withdraw, n=53, 54', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Ca Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Ca Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '5', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '5', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'High Glucose Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Glucose Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Day 84, n=52, 550', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Potassium Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium V4 Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Potassium Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High Sodium Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low Sodium Follow-up/Early Withdraw, n=53, 53', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Day 28, n=58,60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Day 84, n=51, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High TBL Follow-up/Early Withdraw, n=53, 54', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': 'Clinical Chemistry parameters included Alanine Amino Transferase (ALT), Albumin, Alkaline Phosphatase (ALP), Aspartate Amino Transferase (AST), Calcium (Ca), Glucose, Potassium (K), Sodium (Na), and Total Bilirubin (TBL) at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, and at follow-up/Early withdrawal. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All Subject Population'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Abnormal Vital Signs', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'High DBP Screening/Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High DBP Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP V6 Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low DBP Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High SBP Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Screening/ V1 Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low SBP Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HR Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}]}]}, {'title': 'High HR Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'High HR Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '2', 'groupId': 'OG001'}]}]}, {'title': 'High HR Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HR Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HR Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'High HR Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '2', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Follow-up/Early Withdraw, n=55, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'Low HR Any Visit Post Baseline, n=62, 62', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': 'Vital signs included high and low diastolic and systolic blood presure (BP), and high and low heart rate (HR). Vital signs outside the range of potential clinical importance are presented at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, follow-up/Early withdrawal and at any visit post-baseline . Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All Subject Population'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Abnormal 12-lead Electrocardiogram (ECG)', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'CN ECG Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '45', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Screening/ Day 1, n=63, 63', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '43', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Day 12, n=61, 60', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '41', 'groupId': 'OG000'}, {'value': '40', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Day 28, n=58, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '39', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Day 56, n=55, 56', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '36', 'groupId': 'OG000'}, {'value': '38', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Day 84, n=52, 55', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Follow-up/Early Withdraw, n=56, 60', 'categories': [{'measurements': [{'value': '35', 'groupId': 'OG000'}, {'value': '43', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Follow-up/Early Withdraw, n=56, 60', 'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}, {'title': 'CN ECG Any Visit Post Baseline, n=63, 62', 'categories': [{'measurements': [{'value': '51', 'groupId': 'OG000'}, {'value': '51', 'groupId': 'OG001'}]}]}, {'title': 'CS ECG Any Visit Post Baseline, n=63, 62', 'categories': [{'measurements': [{'value': '3', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': "12-lead ECG was obtained using an ECG machine that automatically calculates the heart rate and measures PR, QRS, QT, and QT interval corrected using the Fridericia's formula (QTcF). Clinically non-significant (CN) and Clinically significant (CS) abnormal ECG measurements are presented for Day 1, Day 12, Day 28, Day 56, Day 84, follow-up/Early withdrawal and at any visit post-baseline. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).", 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All Subject Population'}, {'type': 'SECONDARY', 'title': 'Day 1 Plasma Concentration up to 24 Hours (Hrs) Post-dose', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}]}], 'groups': [{'id': 'OG000', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Pre-dose, n=61', 'categories': [{'measurements': [{'value': '33.0', 'spread': 'NA', 'comment': 'Only 5 of the 61 values had not been imputed as zero; therefore, calculation of the SD would result in a potentially misleading value and hence is omitted from the data display (if \\>30% of values are imputed then the SD will not be included).', 'groupId': 'OG000'}]}]}, {'title': '5 min, n=60', 'categories': [{'measurements': [{'value': '476.6', 'spread': '520.85', 'groupId': 'OG000'}]}]}, {'title': '3 hrs, n=61', 'categories': [{'measurements': [{'value': '553.7', 'spread': '326.98', 'groupId': 'OG000'}]}]}, {'title': '24 hrs, n=20', 'categories': [{'measurements': [{'value': '539.0', 'spread': '482.76', 'groupId': 'OG000'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Pre-dose, 5 min, 3 hrs and 24 hrs', 'description': 'Plasma samples were collected at pre-dose, 5 minutes (min), 3 hrs, and 24 hrs post-dose on Day 1. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Pharmacokinetic (PK) Population: all participants in the Safety Population for whom a PK sample was obtained and analyzed. Safety Population comprises of all participants who were randomized.', 'unitOfMeasure': 'pg/mL', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Pharmacokinetic (PK) Population'}, {'type': 'SECONDARY', 'title': 'Trough Concentration After 12 Days, 28 Days, 56 Days and 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '62', 'groupId': 'OG000'}]}], 'groups': [{'id': 'OG000', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Pre-dose Day 12, n=57', 'categories': [{'measurements': [{'value': '1001.8', 'spread': '669.05', 'groupId': 'OG000'}]}]}, {'title': 'Pre-dose Day 28, n=60', 'categories': [{'measurements': [{'value': '1028.8', 'spread': '798.38', 'groupId': 'OG000'}]}]}, {'title': 'Pre-dose Day 56, n=55', 'categories': [{'measurements': [{'value': '1119.8', 'spread': '1389.53', 'groupId': 'OG000'}]}]}, {'title': 'Pre-dose Day 84, n=54', 'categories': [{'measurements': [{'value': '948.6', 'spread': '1078.31', 'groupId': 'OG000'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Pre-dose Day 12, Day 28, Day 56, and Day 84', 'description': 'Trough concentrations are presented for Pre-dose Day 12, Pre-dose Day 28, Pre-dose Day 56, and Pre-dose Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'pg/mL', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'PK Population'}, {'type': 'SECONDARY', 'title': 'Changes From Baseline in Forced Expiratory Volume in One Second (FEV1) Measured Daily', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=55, 58', 'categories': [{'measurements': [{'value': '-70.4', 'spread': '43.07', 'groupId': 'OG000'}, {'value': '-72.2', 'spread': '41.28', 'groupId': 'OG001'}]}]}, {'title': 'Day 84, n=46, 54', 'categories': [{'measurements': [{'value': '-83.3', 'spread': '49.73', 'groupId': 'OG000'}, {'value': '-22.7', 'spread': '46.77', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '0.487', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '-2.0', 'ciLowerLimit': '-118.5', 'ciUpperLimit': '115.3', 'estimateComment': 'Day 28', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.816', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '60.6', 'ciLowerLimit': '-73.3', 'ciUpperLimit': '194.3', 'estimateComment': 'Day 84', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28, and Day 84', 'description': 'FEV1 is the volume of air that can forcibly be blown out in one second. A triplicate FEV1 measurement were taken daily in the morning before dose administration. Baseline is defined as the assessment on Day 1 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84.Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'mL', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Changes From Baseline in Peak Expiratory Flow (PEF) Measured Daily', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=54, 57', 'categories': [{'measurements': [{'value': '-13.12', 'spread': '60.421', 'groupId': 'OG000'}, {'value': '-4.76', 'spread': '57.578', 'groupId': 'OG001'}]}]}, {'title': 'Day 84, n=45, 53', 'categories': [{'measurements': [{'value': '-0.52', 'spread': '65.374', 'groupId': 'OG000'}, {'value': '-0.85', 'spread': '71.170', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28, and Day 84', 'description': 'PEF is the maximal flow (or speed) achieved during the maximally forced expiration initiated at full inspiration. Baseline is defined as the assessment on Day 1 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84.Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'L/min', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Percent Change From Baseline in Diffusion Capacity (DLco, Kco) After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'DLco Day 28, n=53, 56', 'categories': [{'measurements': [{'value': '-2.783', 'spread': '9.3950', 'groupId': 'OG000'}, {'value': '-0.687', 'spread': '8.2655', 'groupId': 'OG001'}]}]}, {'title': 'DLco Day 84, n=45, 51', 'categories': [{'measurements': [{'value': '-2.385', 'spread': '9.6016', 'groupId': 'OG000'}, {'value': '0.560', 'spread': '9.5434', 'groupId': 'OG001'}]}]}, {'title': 'Kco Day 28, n=53, 55', 'categories': [{'measurements': [{'value': '-2.745', 'spread': '9.7851', 'groupId': 'OG000'}, {'value': '-0.875', 'spread': '8.0041', 'groupId': 'OG001'}]}]}, {'title': 'Kco Day 84, n=45, 50', 'categories': [{'measurements': [{'value': '-2.367', 'spread': '10.2835', 'groupId': 'OG000'}, {'value': '-0.759', 'spread': '8.7801', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'DLco is diffusing capacity o f the lungs for carbon monoxide and is defined as the extent to which oxygen passes from the air sacs of the lungs into the blood. KCO is the carbon monoxide transfer coefficient. It is an index of the efficiency of alveolar transfer of carbon monoxide. Baseline is defined as the assessment on Day 2 and percent change from Baseline is the post-Baseline value minus Baseline value/100. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'Percent', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Total Lung Capacity (TLC) After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=53, 59', 'categories': [{'measurements': [{'value': '-0.010', 'groupId': 'OG000', 'lowerLimit': '-0.211', 'upperLimit': '0.190'}, {'value': '-0.155', 'groupId': 'OG001', 'lowerLimit': '-0.344', 'upperLimit': '0.035'}]}]}, {'title': 'Day 84, n=47, 55', 'categories': [{'measurements': [{'value': '-0.149', 'groupId': 'OG000', 'lowerLimit': '-0.462', 'upperLimit': '0.163'}, {'value': '-0.029', 'groupId': 'OG001', 'lowerLimit': '-0.320', 'upperLimit': '0.265'}]}]}], 'analyses': [{'pValue': '0.151', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '-0.144', 'ciLowerLimit': '-0.420', 'ciUpperLimit': '0.133', 'estimateComment': 'Day 28', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.712', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.121', 'ciLowerLimit': '-0.305', 'ciUpperLimit': '0.551', 'estimateComment': 'Day 84', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEDIAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'TLC is the maximum amount of air that can fill the lungs. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Note: values mentioned as 95% confidence interval below are in fact values of 95% credible interval.', 'unitOfMeasure': 'L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Residual Volume After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=53, 59', 'categories': [{'measurements': [{'value': '-0.157', 'groupId': 'OG000', 'lowerLimit': '-0.441', 'upperLimit': '0.129'}, {'value': '0.022', 'groupId': 'OG001', 'lowerLimit': '-0.249', 'upperLimit': '0.292'}]}]}, {'title': 'Day 84, =47, 54', 'categories': [{'measurements': [{'value': '-0.113', 'groupId': 'OG000', 'lowerLimit': '-0.430', 'upperLimit': '0.206'}, {'value': '0.001', 'groupId': 'OG001', 'lowerLimit': '-0.299', 'upperLimit': '0.296'}]}]}], 'analyses': [{'pValue': '0.817', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.180', 'ciLowerLimit': '-0.216', 'ciUpperLimit': '0.570', 'estimateComment': 'Day 28', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.697', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.114', 'ciLowerLimit': '-0.324', 'ciUpperLimit': '0.549', 'estimateComment': 'Day 84', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEDIAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Residual volume is a lung volume representing the amount of air left in the lungs after a forced exhalation. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Note: values mentioned as 95% confidence interval below are in fact values of 95% credible interval.', 'unitOfMeasure': 'L', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Functional Residual Capacity After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=52, 59', 'categories': [{'measurements': [{'value': '0.0010', 'spread': '0.86637', 'groupId': 'OG000'}, {'value': '-0.0919', 'spread': '0.92501', 'groupId': 'OG001'}]}]}, {'title': 'Day 84, =46, 55', 'categories': [{'measurements': [{'value': '-0.2219', 'spread': '1.06874', 'groupId': 'OG000'}, {'value': '-0.0505', 'spread': '1.41910', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Functional residual capacity is the volume of air present in the lungs at the end of passive expiration. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'L', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Specific Resistance (sRaw) After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n= 17, 17', 'categories': [{'measurements': [{'value': '0.9734', 'spread': '0.45833', 'groupId': 'OG000'}, {'value': '0.8372', 'spread': '0.49176', 'groupId': 'OG001'}]}]}, {'title': 'Day 84, n=11, 13', 'categories': [{'measurements': [{'value': '0.9949', 'spread': '0.24484', 'groupId': 'OG000'}, {'value': '0.8495', 'spread': '0.39565', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'sRaw is the measure of specific resistance. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).', 'unitOfMeasure': 'KPa*s', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Change From Baseline in Specific Conductance (sGaw) After 28 Days and After 84 Days of Treatment', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Day 28, n=47, 52', 'categories': [{'measurements': [{'value': '0.875', 'groupId': 'OG000', 'lowerLimit': '0.773', 'upperLimit': '0.990'}, {'value': '1.024', 'groupId': 'OG001', 'lowerLimit': '0.910', 'upperLimit': '1.150'}]}]}, {'title': 'Day 84, =40, 47', 'categories': [{'measurements': [{'value': '0.965', 'groupId': 'OG000', 'lowerLimit': '0.860', 'upperLimit': '1.083'}, {'value': '1.075', 'groupId': 'OG001', 'lowerLimit': '0.967', 'upperLimit': '1.197'}]}]}], 'analyses': [{'pValue': '0.965', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.171', 'ciLowerLimit': '0.988', 'ciUpperLimit': '1.388', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}, {'pValue': '0.913', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Median Difference (Final Values)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '1.114', 'ciLowerLimit': '0.953', 'ciUpperLimit': '1.305', 'statisticalMethod': 'Bayesian repeated measures model', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER_LEGACY', 'statisticalComment': 'Non-informative priors used for all modelling parameters. Unstructured covariance matrix fitted, accounting for correlation within region and visit.'}], 'paramType': 'MEDIAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).Note: values mentioned as 95% confidence interval below are in fact values of 95% Credible Interval.', 'unitOfMeasure': '1/KPA*S', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Questionnaires CAT and MMRC Scale at Baseline, Day 28 and Day 84', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'never cough/cough all the time D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '1.16', 'groupId': 'OG000'}, {'value': '-0.7', 'spread': '1.14', 'groupId': 'OG001'}]}]}, {'title': 'never cough/cough all the time D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.6', 'spread': '1.48', 'groupId': 'OG000'}, {'value': '-0.7', 'spread': '0.99', 'groupId': 'OG001'}]}]}, {'title': 'No phlegm/full of phlegm in chest D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.6', 'spread': '1.26', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.24', 'groupId': 'OG001'}]}]}, {'title': 'No phlegm/full of phlegm in chest D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.8', 'spread': '1.20', 'groupId': 'OG000'}, {'value': '-0.6', 'spread': '1.18', 'groupId': 'OG001'}]}]}, {'title': 'No tightness/very tight chest D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.2', 'spread': '1.30', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.16', 'groupId': 'OG001'}]}]}, {'title': 'No tightness/very tight chest D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.1', 'spread': '1.43', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.34', 'groupId': 'OG001'}]}]}, {'title': 'Hill/stairs nobreathless/breathlessD28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.5', 'spread': '0.98', 'groupId': 'OG000'}, {'value': '-0.5', 'spread': '1.08', 'groupId': 'OG001'}]}]}, {'title': 'Hill/stairs nobreathless/breathless D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '1.43', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.03', 'groupId': 'OG001'}]}]}, {'title': 'Unlimited/limited home activity D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.3', 'spread': '1.43', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.15', 'groupId': 'OG001'}]}]}, {'title': 'Unlimited/limited home activity D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.3', 'spread': '1.24', 'groupId': 'OG000'}, {'value': '-0.1', 'spread': '1.39', 'groupId': 'OG001'}]}]}, {'title': 'Confident/not confident leave home D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '1.24', 'groupId': 'OG000'}, {'value': '-0.1', 'spread': '1.27', 'groupId': 'OG001'}]}]}, {'title': 'Confident/not confident leave homeD84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.2', 'spread': '1.49', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.34', 'groupId': 'OG001'}]}]}, {'title': 'Sound sleep/No sound sleep D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '1.11', 'groupId': 'OG000'}, {'value': '-0.2', 'spread': '1.30', 'groupId': 'OG001'}]}]}, {'title': 'Sound sleep/No sound sleep D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.3', 'spread': '1.60', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.36', 'groupId': 'OG001'}]}]}, {'title': 'Lot of energy/no energy D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.1', 'spread': '1.46', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.22', 'groupId': 'OG001'}]}]}, {'title': 'Lot of energy/no energy D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.2', 'spread': '1.49', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '1.25', 'groupId': 'OG001'}]}]}, {'title': 'CAT Total Score D28, n=58, 60', 'categories': [{'measurements': [{'value': '-2.9', 'spread': '6.05', 'groupId': 'OG000'}, {'value': '-2.6', 'spread': '5.13', 'groupId': 'OG001'}]}]}, {'title': 'CAT Total Score D84, n=53, 55', 'categories': [{'measurements': [{'value': '-3.0', 'spread': '7.16', 'groupId': 'OG000'}, {'value': '-3.1', 'spread': '5.45', 'groupId': 'OG001'}]}]}, {'title': 'MMRC Dyspnoea Score D28, n=58, 60', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '0.75', 'groupId': 'OG000'}, {'value': '-0.2', 'spread': '0.72', 'groupId': 'OG001'}]}]}, {'title': 'MMRC Dyspnoea Score D84, n=53, 55', 'categories': [{'measurements': [{'value': '-0.4', 'spread': '0.95', 'groupId': 'OG000'}, {'value': '-0.3', 'spread': '0.71', 'groupId': 'OG001'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': "The chronic obstructive pulmonary disease (COPD) assessement test (CAT) and Modified Medical Research Council (MMRC) Dyspnea Scale were completed at the indicated timepoints: Baseline, Day 28 and Day 84. CAT and MMRC scales are prestned as: 1.I never cough/I cough all the time 2.I have no phelgm in my chest at all/My chest is completely full of phelgm 3. My chest does not feel tight at all/My chest feels very tight 4.Walk up hilll or stairs not breathless/Walk up hill or stairs very breathless 5. Not limited doing any home activities/Very limited doing any home activities 6. Confident leaving home/No confident leaving home 7. I sleep soundly/I don't sleep soundly because of my lung condition and 8. I have lots of energy/I have no energy at all. Baseline is defined as the assessment on Day 1. Score 0 indicates not troubled with breathlessness to 4:too breathless. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).", 'unitOfMeasure': 'Scores on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}, {'type': 'SECONDARY', 'title': 'Number of Participants With Treatment Failures', 'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'OG000'}, {'value': '63', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'OG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'classes': [{'title': 'Recurrent exacerbation', 'categories': [{'measurements': [{'value': '17', 'groupId': 'OG000'}, {'value': '13', 'groupId': 'OG001'}]}]}, {'title': 'Prolonged Treatment of current exacerbation', 'categories': [{'measurements': [{'value': '9', 'groupId': 'OG000'}, {'value': '7', 'groupId': 'OG001'}]}]}, {'title': 'continuation of treatment with SOC/antibiotics', 'categories': [{'measurements': [{'value': '4', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}, {'title': 'Additional treatment with SOC/antibiotics', 'categories': [{'measurements': [{'value': '6', 'groupId': 'OG000'}, {'value': '6', 'groupId': 'OG001'}]}]}, {'title': 'Requirement of invasive mechanical ventilation', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'NUMBER', 'timeFrame': '13 weeks', 'description': 'Treatment failure types are presented as: recurrent exacerbations, prolonged treatment of current exacerbation (beyond 14 days), additional treatment with systemic / oral corticosteroids and / or antibiotics, and requirement for invasive mechanical ventilation.', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'ITT Population'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'FG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '63'}, {'groupId': 'FG001', 'numSubjects': '63'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '49'}, {'groupId': 'FG001', 'numSubjects': '55'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '14'}, {'groupId': 'FG001', 'numSubjects': '8'}]}], 'dropWithdraws': [{'type': 'Adverse Event', 'reasons': [{'groupId': 'FG000', 'numSubjects': '5'}, {'groupId': 'FG001', 'numSubjects': '5'}]}, {'type': 'Met Protocol Defined Stopping Criteria', 'reasons': [{'groupId': 'FG000', 'numSubjects': '1'}, {'groupId': 'FG001', 'numSubjects': '0'}]}, {'type': 'Lost to Follow-up', 'reasons': [{'groupId': 'FG000', 'numSubjects': '2'}, {'groupId': 'FG001', 'numSubjects': '0'}]}, {'type': 'Physician Decision', 'reasons': [{'groupId': 'FG000', 'numSubjects': '2'}, {'groupId': 'FG001', 'numSubjects': '1'}]}, {'type': 'Withdrawal by Subject', 'reasons': [{'groupId': 'FG000', 'numSubjects': '4'}, {'groupId': 'FG001', 'numSubjects': '2'}]}]}], 'recruitmentDetails': 'The study consisted of a screening visit, a 12-week treatment period, and a 1-2 week post-treatment follow-up. The total duration of the study was 13-14 weeks including the screening visit.', 'preAssignmentDetails': 'Approximately 120 participants with an acute exacerbation of chronic obstructive pulmonary disease (COPD) were randomized (1:1) to GSK 2269557 1000 micrograms (µg) and placebo such that approximately 100 participants complete the study. Participants were also stratified by whether they were willing and able to provide sputum samples at screening.'}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '63', 'groupId': 'BG000'}, {'value': '63', 'groupId': 'BG001'}, {'value': '126', 'groupId': 'BG002'}]}], 'groups': [{'id': 'BG000', 'title': 'Placebo', 'description': 'Participants received placebo two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'BG001', 'title': 'GSK2269557 1000 mcg', 'description': 'Participants received 1000 mcg of GSK2269557 two inhalations per day administered via a dry powder inhaler for a duration of 84 days.'}, {'id': 'BG002', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '64.9', 'spread': '7.88', 'groupId': 'BG000'}, {'value': '65.6', 'spread': '7.14', 'groupId': 'BG001'}, {'value': '65.2', 'spread': '7.50', 'groupId': 'BG002'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'Years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '17', 'groupId': 'BG000'}, {'value': '17', 'groupId': 'BG001'}, {'value': '34', 'groupId': 'BG002'}]}, {'title': 'Male', 'measurements': [{'value': '46', 'groupId': 'BG000'}, {'value': '46', 'groupId': 'BG001'}, {'value': '92', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Race/Ethnicity, Customized', 'classes': [{'title': 'American Indian or Alaskan Native', 'categories': [{'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '1', 'groupId': 'BG001'}, {'value': '1', 'groupId': 'BG002'}]}]}, {'title': 'White - White/Caucasian/European Heritage', 'categories': [{'measurements': [{'value': '63', 'groupId': 'BG000'}, {'value': '62', 'groupId': 'BG001'}, {'value': '125', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE2'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 126}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-03-31', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-08', 'completionDateStruct': {'date': '2016-04-25', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-08-11', 'studyFirstSubmitDate': '2014-11-17', 'resultsFirstSubmitDate': '2016-10-17', 'studyFirstSubmitQcDate': '2014-11-17', 'lastUpdatePostDateStruct': {'date': '2021-08-12', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2017-01-20', 'studyFirstPostDateStruct': {'date': '2014-11-19', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2017-03-09', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2016-02-19', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Change From Baseline in Specific Imaging Airway Volume (siVaw), Measured at FRC and TLC Scan Conditions, Presented in Longitudinal and Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': "siVaw is a measure of the volume in an individual's airway corrected for their lobar volume derived from the high resolution computed tomography (HRCT). It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at longitudinal time points: Screening, Day 12 \\& Day 28 and at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points and SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title)."}], 'secondaryOutcomes': [{'measure': 'Change From Baseline in Imaging Airways Volume: iVaw, Measured at FRC and TLC Scan Conditions, Presented in Longitudinal and Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'iVaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. Data was collected at longitudinal time points: Screening, Day 12 \\& Day 28 and at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points and SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).'}, {'measure': 'Change From Baseline in Imaging Airways Resistance ( iRaw) Measured at FRC and TLC Scan Conditions, Presented in Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'iRaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).'}, {'measure': 'Change From Baseline in Imaging Specific Airways Resistance: siRaw Measured at FRC and TLC Scan Conditions, Presented in Scan Trimmed Scan Types, Measured in 5 Lobes and 5 Regions at Screening, Day 12 and Day 28', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'siRaw was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. It was measured at functional residual volume (FRC) and total lung capacity (TLC). Data was collected at each time point for scan trimmed pairs: SCRD12, SCRD28 \\& D12D28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For SCRD12 \\& SCRD28 scan trimmed pairs the baseline is screening, for D12D28 scan trimmed pair the baseline is D12. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).'}, {'measure': 'Change From Baseline in Lung Lobar Volumes Measured at FRC and TLC Scan Conditions, Presented in Longitudinal Scan Types, Measured in 5 Lobes and 5 Regions at Day 12 and Day 28', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Change from Baseline in lung lobar volumes was measured at functional residual volume (FRC) and total lung capacity (TLC) scan conditions. Data was collected at longitudinal time points: Day 12 \\& Day 28. At each time point it was measure at 5 lobes (RUL, LUL, RML, RLL \\& LLL) and 5 Regions (Upper, Lower, Central, Distal \\& Total). For longitudinal time points the baseline is screening. Change from baseline is the post-Baseline value minus the Baseline value. Only particpants available at the specified time point were analysed (represented by n=X1, X2 in the category title).'}, {'measure': 'Change From Baseline in Imaging Trachea Length and Diameter After 12 Days of Treatment and After 28 Days of Treatment', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Imaging trachea length and diameter was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. TLC is the volume in the lungs at maximal inflation and FRC is the volume in the lungs at the end-expiratory position. The Baseline for the assessment on Day 12 and Day 28 is the Screening value. Change from Baseline is the post-Baseline value minus the Baseline value. The change from Baseline data is presented for Day 12 and Day 28 for trachea length and diameter. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Change From Baseline in Imaging Trachea Length/Diameter After 12 Days of Treatment and After 28 Days of Treatment', 'timeFrame': 'Baseline, Day 12 and Day 28', 'description': 'Imaging trachea length/diameter was derived from HRCT to evaluate the effect of once daily inhaled dose of GSK2269557 on lung parameters. TLC is the volume in the lungs at maximal inflation and FRC is the volume in the lungs at the end-expiratory position. The Baseline for the assessment on Day 12 and Day 28 is the Screening value. Change from Baseline is the post-Baseline value minus the Baseline value. The change from Baseline data is presented for Day 12 and Day 28 for trachea length/diameter. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Number of Participants With Adverse Events (AE)', 'timeFrame': 'From start of IP through the Study Phase (84 days post-dose) (assessed up to follow-up duration of approximately 100 days)', 'description': 'An AE is defined as any untoward medical occurrence in a participant, temporally associated with the use of a medicinal product, whether or not considered related to the medicinal product. Adverse events were collected from the start of study treatment until the follow-up contact.'}, {'measure': 'Number of Participants With Abnormal Hematology Parameters', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 Days)', 'description': 'Hematology parameter included Hematocrit (HCT), Hemoglobin (HB), Lymphocytes (LC), Platelet Count (PC), Total Neutrophils (TN), and White Blood Cell (WBC) count at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, and at follow-up/Early withdrawal. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Number of Participants With Abnormal Clinical Chemistry Parameters', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': 'Clinical Chemistry parameters included Alanine Amino Transferase (ALT), Albumin, Alkaline Phosphatase (ALP), Aspartate Amino Transferase (AST), Calcium (Ca), Glucose, Potassium (K), Sodium (Na), and Total Bilirubin (TBL) at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, and at follow-up/Early withdrawal. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Number of Participants With Abnormal Vital Signs', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': 'Vital signs included high and low diastolic and systolic blood presure (BP), and high and low heart rate (HR). Vital signs outside the range of potential clinical importance are presented at the indicated timepoints: Day 1, Day 12, Day 28, Day 56, Day 84, follow-up/Early withdrawal and at any visit post-baseline . Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Number of Participants With Abnormal 12-lead Electrocardiogram (ECG)', 'timeFrame': 'Day 1, Day 12, Day 28, Day 56, Day 84 and at follow-up (approximately 100 days)', 'description': "12-lead ECG was obtained using an ECG machine that automatically calculates the heart rate and measures PR, QRS, QT, and QT interval corrected using the Fridericia's formula (QTcF). Clinically non-significant (CN) and Clinically significant (CS) abnormal ECG measurements are presented for Day 1, Day 12, Day 28, Day 56, Day 84, follow-up/Early withdrawal and at any visit post-baseline. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles)."}, {'measure': 'Day 1 Plasma Concentration up to 24 Hours (Hrs) Post-dose', 'timeFrame': 'Pre-dose, 5 min, 3 hrs and 24 hrs', 'description': 'Plasma samples were collected at pre-dose, 5 minutes (min), 3 hrs, and 24 hrs post-dose on Day 1. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Pharmacokinetic (PK) Population: all participants in the Safety Population for whom a PK sample was obtained and analyzed. Safety Population comprises of all participants who were randomized.'}, {'measure': 'Trough Concentration After 12 Days, 28 Days, 56 Days and 84 Days of Treatment', 'timeFrame': 'Pre-dose Day 12, Day 28, Day 56, and Day 84', 'description': 'Trough concentrations are presented for Pre-dose Day 12, Pre-dose Day 28, Pre-dose Day 56, and Pre-dose Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Changes From Baseline in Forced Expiratory Volume in One Second (FEV1) Measured Daily', 'timeFrame': 'Baseline, Day 28, and Day 84', 'description': 'FEV1 is the volume of air that can forcibly be blown out in one second. A triplicate FEV1 measurement were taken daily in the morning before dose administration. Baseline is defined as the assessment on Day 1 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84.Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Changes From Baseline in Peak Expiratory Flow (PEF) Measured Daily', 'timeFrame': 'Baseline, Day 28, and Day 84', 'description': 'PEF is the maximal flow (or speed) achieved during the maximally forced expiration initiated at full inspiration. Baseline is defined as the assessment on Day 1 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84.Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Percent Change From Baseline in Diffusion Capacity (DLco, Kco) After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'DLco is diffusing capacity o f the lungs for carbon monoxide and is defined as the extent to which oxygen passes from the air sacs of the lungs into the blood. KCO is the carbon monoxide transfer coefficient. It is an index of the efficiency of alveolar transfer of carbon monoxide. Baseline is defined as the assessment on Day 2 and percent change from Baseline is the post-Baseline value minus Baseline value/100. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Change From Baseline in Total Lung Capacity (TLC) After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'TLC is the maximum amount of air that can fill the lungs. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Note: values mentioned as 95% confidence interval below are in fact values of 95% credible interval.'}, {'measure': 'Change From Baseline in Residual Volume After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Residual volume is a lung volume representing the amount of air left in the lungs after a forced exhalation. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles). Note: values mentioned as 95% confidence interval below are in fact values of 95% credible interval.'}, {'measure': 'Change From Baseline in Functional Residual Capacity After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Functional residual capacity is the volume of air present in the lungs at the end of passive expiration. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Change From Baseline in Specific Resistance (sRaw) After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'sRaw is the measure of specific resistance. Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).'}, {'measure': 'Change From Baseline in Specific Conductance (sGaw) After 28 Days and After 84 Days of Treatment', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': 'Baseline is defined as the assessment on Day 2 and change from Baseline is the post-Baseline value minus Baseline value. Change from Baseline data is presented for Day 28 and Day 84. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles).Note: values mentioned as 95% confidence interval below are in fact values of 95% Credible Interval.'}, {'measure': 'Questionnaires CAT and MMRC Scale at Baseline, Day 28 and Day 84', 'timeFrame': 'Baseline, Day 28 and Day 84', 'description': "The chronic obstructive pulmonary disease (COPD) assessement test (CAT) and Modified Medical Research Council (MMRC) Dyspnea Scale were completed at the indicated timepoints: Baseline, Day 28 and Day 84. CAT and MMRC scales are prestned as: 1.I never cough/I cough all the time 2.I have no phelgm in my chest at all/My chest is completely full of phelgm 3. My chest does not feel tight at all/My chest feels very tight 4.Walk up hilll or stairs not breathless/Walk up hill or stairs very breathless 5. Not limited doing any home activities/Very limited doing any home activities 6. Confident leaving home/No confident leaving home 7. I sleep soundly/I don't sleep soundly because of my lung condition and 8. I have lots of energy/I have no energy at all. Baseline is defined as the assessment on Day 1. Score 0 indicates not troubled with breathlessness to 4:too breathless. Only those participants available at the specified time points were analyzed (represented by n=X, X in the category titles)."}, {'measure': 'Number of Participants With Treatment Failures', 'timeFrame': '13 weeks', 'description': 'Treatment failure types are presented as: recurrent exacerbations, prolonged treatment of current exacerbation (beyond 14 days), additional treatment with systemic / oral corticosteroids and / or antibiotics, and requirement for invasive mechanical ventilation.'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['functional respiratory capacity', 'High-resolution computed tomography', 'GSK2269557', 'acute exacerbation of COPD', 'lung capacity'], 'conditions': ['Pulmonary Disease, Chronic Obstructive']}, 'referencesModule': {'references': [{'pmid': '34113093', 'type': 'BACKGROUND', 'citation': 'Cahn A, Hamblin JN, Robertson J, Begg M, Jarvis E, Wilson R, Dear G, Leemereise C, Cui Y, Mizuma M, Montembault M, Van Holsbeke C, Vos W, De Backer W, De Backer J, Hessel EM. An Inhaled PI3Kdelta Inhibitor Improves Recovery in Acutely Exacerbating COPD Patients: A Randomized Trial. Int J Chron Obstruct Pulmon Dis. 2021 Jun 3;16:1607-1619. doi: 10.2147/COPD.S309129. eCollection 2021.'}]}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to evaluate the efficacy of GSK2269557 administered in addition to standard of care in adult subjects diagnosed with an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Additionally study will also assess safety, tolerability and pharmacokinetic data. The total duration of the study will be 13-14 weeks including screening, treatment period and a follow up visit. Subjects will receive once daily study treatment administration starting on Day 1. Study is planned to recruit approximately 120 subjects such that approximately 100 subjects complete the study.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '40 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Between 40 and 80 years of age inclusive, at the time of signing the informed consent\n* The subject has a confirmed and established diagnosis of COPD, as defined by the global initiative for chronic Obstructive Lung Disease (GOLD) guidelines for at least 6 months prior to entry.\n* The subject has a post-bronchodilator FEV1/Forced Vital Capacity (FVC) \\< 0.7 and FEV1 \\<= 80 % of predicted (Predictions should be according to the European Community of Coal and Steel \\[ECCS\\] equations), documented in the last 5 years.\n* Disease severity: Acute exacerbation of COPD requiring an escalation in therapy to include corticosteroid and antibiotics. Acute exacerbation to be confirmed by an experienced physician and represent a recent change in at least two major and one minor symptoms, one major and two minor symptoms, or all 3 major symptoms. Major symptoms: subjective increase in dyspnea, increase in sputum volume, and change in sputum colour. Minor symptoms: cough, wheeze and sore throat.\n* The subject is a smoker or an ex-smoker with a smoking history of at least 10 pack years (pack years = \\[cigarettes per day smoked/20 x number of years smoked\\])\n* Body weight \\>= 45 kilogram (kg) and body mass index (BMI) within the range 18 - 32 kg/metered squared (m\\^2) (inclusive).\n* Male\n* Female subject : is eligible to participate if she is not pregnant (as confirmed by a negative urine human chorionic gonadotrophin \\[hCG\\] test), not lactating, and at least one of the following conditions applies:\n\nNon-reproductive potential defined as: Pre-menopausal females with one of the following: documented tubal ligation, documented hysteroscopic tubal occlusion procedure with follow-up confirmation of bilateral tubal occlusion, hysterectomy and documented bilateral oophorectomy. Postmenopausal defined as 12 months of spontaneous amenorrhea (in questionable cases a blood sample with simultaneous follicle stimulating hormone \\[FSH\\] and estradiol levels consistent with menopause (refer to laboratory reference ranges for confirmatory levels). Females on hormone replacement therapy (HRT) and whose menopausal status is in doubt will be required to use one of the highly effective contraception methods if they wish to continue their HRT during the study. Otherwise, they must discontinue HRT to allow confirmation of post-menopausal status prior to study enrolment.\n\nReproductive potential and agrees to follow one of the options listed below in the GSK Modified List of Highly Effective Methods for Avoiding Pregnancy in Females of Reproductive Potential (FRP) requirements from 30 days prior to the first dose of study medication and until completion of the follow-up visit.\n\nGlaxoSmithKline (GSK) Modified List of Highly Effective Methods for Avoiding Pregnancy in Females of Reproductive Potential (FRP):\n\nContraceptive subdermal implant that meets the standard operating procedure (SOP) effectiveness criteria including a \\<1% rate of failure per year, as stated in the product label.\n\nIntrauterine device or intrauterine system that meets the SOP effectiveness criteria including a \\<1% rate of failure per year, as stated in the product label.\n\nOral Contraceptive, either combined or progestogen alone. Injectable progestogen. Contraceptive vaginal ring. Percutaneous contraceptive patches. Male partner sterilization with documentation of azoospermia prior to the female subject's entry into the study, and this male is the sole partner for that subject.\n\nMale condom combined with a vaginal spermicide (foam, gel, film, cream, or suppository).\n\n* Male subjects with female partners of child bearing potential must comply with the following contraception requirements from the time of first dose of study medication until after the completion of the follow up visit.\n\nVasectomy with documentation of azoospermia. Male condom plus partner use of one of the contraceptive options below: Contraceptive subdermal implant that meets the SOP effectiveness criteria including a \\<1% rate of failure per year, as stated in the product label. Intrauterine device or intrauterine system that meets the SOP effectiveness criteria including a \\<1% rate of failure per year, as stated in the product label. Oral Contraceptive, either combined or progestogen alone or injectable progestogen. Contraceptive vaginal ring. Percutaneous contraceptive patches.\n\nThese allowed methods of contraception are only effective when used consistently, correctly and in accordance with the product label. The investigator is responsible for ensuring that subjects understand how to properly use these methods of contraception.\n\n* Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the consent form and in the study protocol.\n\nExclusion Criteria:\n\n* To avoid recruitment of subjects with a severe COPD exacerbation, the presence of any one of the following severity criteria will render the subject ineligible for inclusion in the study:\n\nNeed for invasive mechanical ventilation (short term (\\< 48hour) Non-invasive Ventilation (NIV) or Continuous Positive Airway Pressure \\[CPAP\\] is acceptable).\n\nHaemodynamic instability or clinically significant heart failure. Confusion.\n\n* Subjects who have a history or current medical conditions or diseases that are not well controlled and, which as judged by the Investigator, may affect subject safety or influence the outcome of the study. (Note: Patients with adequately treated and well controlled concurrent medical conditions \\[e.g. hypertension or non-insulin dependent diabetes mellitus\\] are permitted to be entered into the study).\n* Subject has a diagnosis of active tuberculosis, lung cancer, clinically overt bronchiectasis, pulmonary fibrosis, asthma or any other respiratory condition that might, in the opinion of the investigator, compromise the safety of the subject or affect the interpretation of the results.\n* Alanine aminotransferase \\>2x upper limit of normal (ULN) and bilirubin \\>1.5xULN (isolated bilirubin \\>1.5xULN is acceptable if bilirubin is fractionated and direct bilirubin \\<35%).\n* A subject with a clinical abnormality or laboratory parameter(s) which is/are not specifically listed in the exclusion criteria, outside of the reference range for the population being studied may be included if the Investigator \\[in consultation with the GSK Medical Monitor if required\\] documents that the finding is unlikely to introduce additional risk factors and will not interfere with the study procedures.\n* Current or chronic history of liver disease, or known hepatic or biliary abnormalities (with the exception of Gilbert's syndrome or asymptomatic gallstones).\n* ECG indicative of an acute cardiac event (e.g. Myocardial Infarction) or demonstrating a clinically significant arrhythmia requiring treatment.\n* QTcF \\> 450 millisecond (msec) or QTcF \\> 480 msec in subjects with Bundle Branch Block, based on single QTcF value.\n* Subjects who have undergone lung volume reduction surgery.\n* Subject is currently on chronic treatment with macrolides; long term oxygen therapy (\\> 15 hours/day).\n* The subject has been on chronic treatment with anti-Tumour Necrosis Factor (anti-TNF), anti-Interleukin-1 (anti-IL1), or any other immunosuppressive therapy within 60 days prior to dosing.\n* History of regular alcohol consumption within 6 months of the study defined as an average weekly intake of \\>28 units for males or \\>21 units for females. One unit is equivalent to 8 gram of alcohol: a half-pint ( equivalent to 240 milliliter \\[mL\\]) of beer, 1 glass (125 mL) of wine or 1 (25 mL) measure of spirits.\n* History of sensitivity to any of the study medications, or components thereof (such as lactose) or a history of drug or other allergy that, in the opinion of the investigator or Medical Monitor, contraindicates their participation.\n* A known (historical) positive test for human immune virus (HIV) antibody.\n* Presence of hepatitis B surface antigen (HBsAg), positive hepatitis C antibody test result at screening or within 3 months prior to first dose of study treatment. NOTE: Because of the short window for screening, treatment with GSK2269557 may start before receiving the result of the hepatitis tests. If subsequently the test is found to be positive, the subject may be withdrawn, as judged by the Principal Investigator in consultation with the Medical Monitor.\n* Where participation in the study would result in donation of blood or blood products in excess of 500 mL within 56 days.\n* The subject has participated in a clinical trial and has received an investigational product within the following time period prior to the first dosing day in the current study: 30 days, 5 half-lives or twice the duration of the biological effect of the investigational product (whichever is longer).\n* Exposure to more than 4 investigational medicinal products within 12 months prior to the first dosing day."}, 'identificationModule': {'nctId': 'NCT02294734', 'briefTitle': 'An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease', 'organization': {'class': 'INDUSTRY', 'fullName': 'GlaxoSmithKline'}, 'officialTitle': 'A Randomised, Double-blind (Sponsor Unblinded), Placebo-controlled, Parallel-group, Multicentre Study to Evaluate the Efficacy and Safety of GSK2269557 Administered in Addition to Standard of Care in Adult Subjects Diagnosed With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease', 'orgStudyIdInfo': {'id': '116678'}, 'secondaryIdInfos': [{'id': '2014-001972-70', 'type': 'EUDRACT_NUMBER'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'GSK2269557 repeat dose', 'description': "Participants will receive 2 inhalation of GSK2269557 dry powder once daily via DISKUS™ 'device' (DISKUS is a trademark of the GSK group of companies)", 'interventionNames': ['Drug: GSK2269557']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'Matching placebo repeat dose', 'description': "Participants will receive 2 inhalation matching placebo dry powder once daily via DISKUS 'device'", 'interventionNames': ['Drug: Placebo']}], 'interventions': [{'name': 'GSK2269557', 'type': 'DRUG', 'description': "Dry powder for inhalation via DISKUS 'device' with unit dose strength of 500 micrograms (mcg) per actuation with total dose of 1000 mcg daily", 'armGroupLabels': ['GSK2269557 repeat dose']}, {'name': 'Placebo', 'type': 'DRUG', 'description': "Dry powder for inhalation via DISKUS 'device'", 'armGroupLabels': ['Matching placebo repeat dose']}]}, 'contactsLocationsModule': {'locations': [{'zip': '2650', 'city': 'Edegem', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.15662, 'lon': 4.44504}}, {'zip': '5101', 'city': 'Erpent', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.45116, 'lon': 4.90557}}, {'zip': 'DK-9100', 'city': 'Aalborg', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.048, 'lon': 9.9187}}, {'zip': 'DK-2400', 'city': 'Copenhagen', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.67594, 'lon': 12.56553}}, {'zip': '2650', 'city': 'Hvidovre', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.64297, 'lon': 12.47708}}, {'zip': '5000 Odense C', 'city': 'Odense', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.39594, 'lon': 10.38831}}, {'zip': '7609 PP', 'city': 'Almelo', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.35667, 'lon': 6.6625}}, {'zip': '5623 EJ', 'city': 'Eindhoven', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.44083, 'lon': 5.47778}}, {'zip': '7207 AE', 'city': 'Zutphen', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.13833, 'lon': 6.20139}}, {'zip': '050159', 'city': 'Bucharest', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '300310', 'city': 'Timișoara', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.75372, 'lon': 21.22571}}, {'zip': '650002', 'city': 'Kemerovo', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.35417, 'lon': 86.10435}}, {'zip': '105 077', 'city': 'Moscow', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '194291', 'city': 'Saint Petersburg', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 59.93863, 'lon': 30.31413}}, {'zip': '600023', 'city': 'Vladimir', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.13854, 'lon': 40.39976}}, {'zip': '150003', 'city': 'Yaroslavl', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.62987, 'lon': 39.87368}}, {'zip': '620109', 'city': 'Yekaterinburg', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.85733, 'lon': 60.61529}}], 'overallOfficials': [{'name': 'GSK Clinical Trials', 'role': 'STUDY_DIRECTOR', 'affiliation': 'GlaxoSmithKline'}]}, 'ipdSharingStatementModule': {'url': 'https://www.clinicalstudydatarequest.com/Posting.aspx?ID=20859', 'infoTypes': ['STUDY_PROTOCOL', 'SAP', 'ICF', 'CSR'], 'timeFrame': 'IPD is available via the Clinical Study Data Request site (copy the URL below to your browser)', 'ipdSharing': 'YES', 'description': 'IPD for this study is available via the Clinical Study Data Request site', 'accessCriteria': 'Access is provided after a research proposal is submitted and has received approval from the Independent Review Panel and after a Data Sharing Agreement is in place. Access is provided for an initial period of 12 months but an extension can be granted, when justified, for up to another 12 months.'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'GlaxoSmithKline', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}