Ignite Creation Date:
2025-12-25 @ 2:29 AM
Ignite Modification Date:
2026-02-22 @ 4:13 AM
Study NCT ID:
NCT00790634
Status:
UNKNOWN
Last Update Posted:
2008-11-13
First Post:
2008-11-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D010300', 'term': 'Parkinson Disease'}, {'id': 'D009771', 'term': 'Obsessive-Compulsive Disorder'}], 'ancestors': [{'id': 'D020734', 'term': 'Parkinsonian Disorders'}, {'id': 'D001480', 'term': 'Basal Ganglia Diseases'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D009069', 'term': 'Movement Disorders'}, {'id': 'D000080874', 'term': 'Synucleinopathies'}, {'id': 'D019636', 'term': 'Neurodegenerative Diseases'}, {'id': 'D001008', 'term': 'Anxiety Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 100}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2008-12'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2008-11', 'completionDateStruct': {'date': '2011-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2008-11-12', 'studyFirstSubmitDate': '2008-11-12', 'studyFirstSubmitQcDate': '2008-11-12', 'lastUpdatePostDateStruct': {'date': '2008-11-13', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-11-13', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-12', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ["Parkinson's Disease", 'Obsessive-Compulsive Disorder']}, 'descriptionModule': {'briefSummary': "The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'maximumAge': '85 Years', 'minimumAge': '16 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'private and hospital-based clinics, healthy volunteers', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* idiopathic PD or\n* OCD\n* for control group - age-matched to study groups\n\nExclusion Criteria:\n\n* psychotic symptoms (past or present)\n* head injury with loss of consciousness\n* other neurological conditions (excepting PD in PD group)\n* for OCD group - use of dopaminergic medications'}, 'identificationModule': {'nctId': 'NCT00790634', 'briefTitle': 'Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD', 'organization': {'class': 'OTHER_GOV', 'fullName': 'Sheba Medical Center'}, 'officialTitle': "Characterizing Mechanisms of Fronto-Subcortical Dysfunction: A Comparison Between Parkinson's Disease and Obsessive-Compulsive Disorder", 'orgStudyIdInfo': {'id': 'SHEBA-08-5473-SH-CTIL'}}, 'armsInterventionsModule': {'armGroups': [{'label': "Parkinson's Disease", 'description': "Patients with idiopathic Parkinson's disease"}, {'label': 'Obsessive-compulsive disorder', 'description': 'Individuals with a diagnosis of obsessive-compulsive disorder'}, {'label': 'OCD controls', 'description': 'Healthy controls, matched in age and number to obsessive-compulsive group'}, {'label': 'PD controls', 'description': "Healthy controls, matched in age and number to Parkinson's disease group"}]}, 'contactsLocationsModule': {'centralContacts': [{'name': 'Sharon Hassin, MD', 'role': 'CONTACT', 'email': 'shassin@post.tau.ac.il', 'phone': '97235305791'}, {'name': 'Sari Meril, M.Sc', 'role': 'CONTACT', 'phone': '972'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Sheba Medical Center', 'class': 'OTHER_GOV'}, 'collaborators': [{'name': 'University of Haifa', 'class': 'OTHER'}, {'name': 'Israel Science Foundation', 'class': 'OTHER'}], 'responsibleParty': {'oldNameTitle': 'Dr. Sharon Hassin, principal investigator', 'oldOrganization': 'Sheba Medical Center'}}}}