Ignite Creation Date:
2025-12-25 @ 2:22 AM
Ignite Modification Date:
2025-12-26 @ 4:49 PM
Study NCT ID:
NCT03406234
Status:
COMPLETED
Last Update Posted:
2018-01-23
First Post:
2018-01-08
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Observational Study on a Chinese Population
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009748', 'term': 'Nutrition Disorders'}, {'id': 'D020022', 'term': 'Genetic Predisposition to Disease'}], 'ancestors': [{'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D004198', 'term': 'Disease Susceptibility'}, {'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Blood.'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 2650}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2013-01-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-01', 'completionDateStruct': {'date': '2013-12-31', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2018-01-12', 'studyFirstSubmitDate': '2018-01-08', 'studyFirstSubmitQcDate': '2018-01-12', 'lastUpdatePostDateStruct': {'date': '2018-01-23', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2018-01-23', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2013-12-31', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Circulating 25OHD concentration.', 'timeFrame': 'Jan., 2014 - May., 2015'}], 'secondaryOutcomes': [{'measure': 'Body mass index', 'timeFrame': 'Jan.-Dec., 2013'}, {'measure': 'Plasma glucose', 'timeFrame': 'Jan.-Dec., 2013'}, {'measure': 'DNA polymorphisms', 'timeFrame': 'Jan., 2014 - Dec., 2017'}, {'measure': 'Plasma lipids', 'timeFrame': 'Jan.-Dec., 2013'}, {'measure': 'Blood pressure', 'timeFrame': 'Jan.-Dec., 2013'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Metabolic Disease', 'Nutrition Disorders', 'Genetic Predisposition to Disease']}, 'referencesModule': {'references': [{'pmid': '28088200', 'type': 'RESULT', 'citation': 'Chen J, Yun C, He Y, Piao J, Yang L, Yang X. Vitamin D status among the elderly Chinese population: a cross-sectional analysis of the 2010-2013 China national nutrition and health survey (CNNHS). Nutr J. 2017 Jan 14;16(1):3. doi: 10.1186/s12937-016-0224-3.'}, {'pmid': '23548751', 'type': 'RESULT', 'citation': 'Santos BR, Mascarenhas LP, Boguszewski MC, Spritzer PM. Variations in the vitamin D-binding protein (DBP) gene are related to lower 25-hydroxyvitamin D levels in healthy girls: a cross-sectional study. Horm Res Paediatr. 2013;79:162-8. doi: 10.1159/000348847. Epub 2013 Mar 20.'}, {'pmid': '21684333', 'type': 'RESULT', 'citation': 'Gozdzik A, Zhu J, Wong BY, Fu L, Cole DE, Parra EJ. Association of vitamin D binding protein (VDBP) polymorphisms and serum 25(OH)D concentrations in a sample of young Canadian adults of different ancestry. J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):405-12. doi: 10.1016/j.jsbmb.2011.05.009. Epub 2011 Jun 12.'}, {'pmid': '30651747', 'type': 'DERIVED', 'citation': 'Zhou JC, Zhu Y, Gong C, Liang X, Zhou X, Xu Y, Lyu D, Mo J, Xu J, Song J, Che X, Sun S, Huang C, Liu XL. The GC2 haplotype of the vitamin D binding protein is a risk factor for a low plasma 25-hydroxyvitamin D concentration in a Han Chinese population. Nutr Metab (Lond). 2019 Jan 14;16:5. doi: 10.1186/s12986-019-0332-0. eCollection 2019.'}]}, 'descriptionModule': {'briefSummary': 'An observational study was conducted in a health examination center to distinguish risk factors for health in a randomly recruited volunteers of Chinese population.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '85 Years', 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Both males and females were included.', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Han population, living in Shenzhen City for \\> 2 y, not in pregnancy, without hepatic diseases and renal diseases\n\nExclusion Criteria:\n\n* caught by organic diseases'}, 'identificationModule': {'nctId': 'NCT03406234', 'briefTitle': 'Observational Study on a Chinese Population', 'organization': {'class': 'OTHER', 'fullName': 'Shenzhen Center for Chronic Disease Control'}, 'officialTitle': 'Observational Study on the Risk Factors for Health in a Chinese Population', 'orgStudyIdInfo': {'id': 'QLS2013'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'A group of participants', 'interventionNames': ['Other: No intervention.']}], 'interventions': [{'name': 'No intervention.', 'type': 'OTHER', 'description': 'Cross-sectional observation without interventions.', 'armGroupLabels': ['A group of participants']}]}, 'contactsLocationsModule': {'locations': [{'zip': '518020', 'city': 'Shenzhen', 'state': 'Guangdong', 'country': 'China', 'facility': 'Shenzhen Center for Chronic Disease Control', 'geoPoint': {'lat': 22.54554, 'lon': 114.0683}}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Shenzhen Center for Chronic Disease Control', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Director of Molecular Biology Laboratory', 'investigatorFullName': 'Zhou Ji-Chang', 'investigatorAffiliation': 'Shenzhen Center for Chronic Disease Control'}}}}