Ignite Creation Date:
2025-12-25 @ 2:22 AM
Ignite Modification Date:
2026-02-25 @ 10:04 PM
Study NCT ID:
NCT01462734
Status:
COMPLETED
Last Update Posted:
2015-04-01
First Post:
2011-10-26
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
MicroRNA Expression in Human Blood Serum and Vitreous Body
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D016133', 'term': 'Polymerase Chain Reaction'}], 'ancestors': [{'id': 'D021141', 'term': 'Nucleic Acid Amplification Techniques'}, {'id': 'D005821', 'term': 'Genetic Techniques'}, {'id': 'D008919', 'term': 'Investigative Techniques'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': '3ml of blood serum and 1ml of vitreous'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 8}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2011-10'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2015-03', 'lastUpdateSubmitDate': '2015-03-31', 'studyFirstSubmitDate': '2011-10-26', 'studyFirstSubmitQcDate': '2011-10-27', 'lastUpdatePostDateStruct': {'date': '2015-04-01', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-10-31', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2014-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'MicroRNA expression profile in human vitreous investigated by PCR', 'timeFrame': '1month'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['MicroRNA Expression Profile in Human Vitreous']}, 'descriptionModule': {'briefSummary': 'MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear. Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of macula hole patients which is suggested to be similar to that of healthy patients.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Female pateints undergoing vitrectomy for macula hole without previous ocular or systemic disease', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Female macula hole patients without previous ocular or systemic disease.'}, 'identificationModule': {'nctId': 'NCT01462734', 'briefTitle': 'MicroRNA Expression in Human Blood Serum and Vitreous Body', 'organization': {'class': 'OTHER', 'fullName': 'Kyorin University'}, 'officialTitle': 'MicroRNA Expression in Human Blood Serum and Vitreous Body', 'orgStudyIdInfo': {'id': 'No. 461'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'human vitreous, human blood serum, PCR', 'description': 'Vitreous and bloodserum samples from macula hole patients without previous ocular or systemic disease', 'interventionNames': ['Procedure: human vitreous and blood serum sampling, PCR']}], 'interventions': [{'name': 'human vitreous and blood serum sampling, PCR', 'type': 'PROCEDURE', 'description': '1ml of human vitreous and 3ml of human blood serum', 'armGroupLabels': ['human vitreous, human blood serum, PCR']}]}, 'contactsLocationsModule': {'locations': [{'zip': '181-8611', 'city': 'Tokyo', 'state': 'Mitakasi Sinkawa6-20-2', 'country': 'Japan', 'facility': 'Kyorin University School Of Medicine', 'geoPoint': {'lat': 35.6895, 'lon': 139.69171}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Kyorin University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'MD', 'investigatorFullName': 'Kazunari Hirota', 'investigatorAffiliation': 'Kyorin University'}}}}