Ignite Creation Date:
2025-12-25 @ 2:21 AM
Ignite Modification Date:
2026-03-05 @ 10:35 PM
Study NCT ID:
NCT00474734
Status:
UNKNOWN
Last Update Posted:
2007-05-17
First Post:
2007-05-15
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Intravascular Ultrasound for Hepatocellular Carcinoma Staging
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D006528', 'term': 'Carcinoma, Hepatocellular'}], 'ancestors': [{'id': 'D000230', 'term': 'Adenocarcinoma'}, {'id': 'D002277', 'term': 'Carcinoma'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D008113', 'term': 'Liver Neoplasms'}, {'id': 'D004067', 'term': 'Digestive System Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D004066', 'term': 'Digestive System Diseases'}, {'id': 'D008107', 'term': 'Liver Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'DEFINED_POPULATION'}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2007-05'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-05', 'completionDateStruct': {'date': '2007-09', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2007-05-16', 'studyFirstSubmitDate': '2007-05-15', 'studyFirstSubmitQcDate': '2007-05-16', 'lastUpdatePostDateStruct': {'date': '2007-05-17', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-05-17', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['hepatocellular carcinoma', 'liver transplantation', 'staging', 'intravascular ultrasound'], 'conditions': ['Hepatocellular Carcinoma']}, 'descriptionModule': {'briefSummary': 'To diagnose hepatocellular carcinoma (HCC) and to determine the extent of the disease, a triphasic CT scan or a magnetic resonance imaging are required. The characterization of hepatic nodules is more difficult when the HCC lesions have a diameter of less than 2 cm.\n\nSince accuracy in the assessment of the number and the size of HCC nodules, as well as of the invasion of blood vessels is crucial to determine outcome after liver transplantation due to tumour recurrence, there is a need for techniques with a higher definition potential.\n\nAs a consequence, to improve outcome and to optimize organ allocation, patients on the liver transplantation waiting list might benefit from intravascular ultrasound as an additional examination to complete the pre-transplant tumour staging process.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* hepatocellular carcinoma nodules\n* patient on liver transplantation waiting list\n* written informed consent\n\nExclusion Criteria:\n\n* thrombosis of hepatic veins or vena cava'}, 'identificationModule': {'nctId': 'NCT00474734', 'briefTitle': 'Intravascular Ultrasound for Hepatocellular Carcinoma Staging', 'nctIdAliases': ['NCT00472979'], 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Geneva'}, 'officialTitle': 'Intravascular Ultrasound for the Staging of Hepatocellular Carcinoma: a Pilot Study', 'orgStudyIdInfo': {'id': '07-063'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Intravascular ultrasound of the liver', 'type': 'DEVICE'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Geneva', 'status': 'RECRUITING', 'country': 'Switzerland', 'contacts': [{'name': 'Andrea De Gottardi, MD PhD', 'role': 'CONTACT', 'email': 'andrea.degottardi@hcuge.ch', 'phone': '+41 22 37 29 256'}], 'facility': 'University Hospital Geneva', 'geoPoint': {'lat': 46.20222, 'lon': 6.14569}}], 'centralContacts': [{'name': 'Antoine Hadengue, Prof.', 'role': 'CONTACT', 'email': 'antoine.hadengue@hcuge.ch', 'phone': '+41 22 37 29 340'}], 'overallOfficials': [{'name': 'Antoine Hadengue, Prof.', 'role': 'STUDY_CHAIR', 'affiliation': 'University Hospital, Geneva'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Geneva', 'class': 'OTHER'}}}}