Ignite Creation Date:
2025-12-24 @ 2:22 PM
Ignite Modification Date:
2026-03-05 @ 8:40 AM
Study NCT ID:
NCT04995159
Status:
NOT_YET_RECRUITING
Last Update Posted:
2021-08-06
First Post:
2021-07-29
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003327', 'term': 'Coronary Disease'}], 'ancestors': [{'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D000080903', 'term': 'Dual Anti-Platelet Therapy'}], 'ancestors': [{'id': 'D004359', 'term': 'Drug Therapy, Combination'}, {'id': 'D004358', 'term': 'Drug Therapy'}, {'id': 'D013812', 'term': 'Therapeutics'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 2150}}, 'statusModule': {'overallStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2021-09', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-07', 'completionDateStruct': {'date': '2028-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2021-07-29', 'studyFirstSubmitDate': '2021-07-29', 'studyFirstSubmitQcDate': '2021-07-29', 'lastUpdatePostDateStruct': {'date': '2021-08-06', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2021-08-06', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2026-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Net adverse clinical event (NACE)', 'timeFrame': '3 years', 'description': 'NACE includes POCE (including all-cause death, all non-fatal myocardial infarction (Universal Definition of Myocardial Infarction, 4th Edition), any revascularization, and stroke), and major bleeding events of grade 2, 3, and 5 as defined by BARC.'}], 'secondaryOutcomes': [{'measure': 'Target lesion failure (TLF)', 'timeFrame': '3 years', 'description': 'Target lesion failure (TLF) includes cardiac death, target vessel myocardial infarction (TV-MI) and ischemic-driven target lesion revascularization (ID-TLR).'}, {'measure': 'Comparison of net adverse clinical events', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 4 years, and 5 years'}, {'measure': 'Bleeding events of grade 3 and 5 as defined by BARC', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'Bleeding events of grade 2, 3 and 5 as defined by BARC', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'Bleeding events of grade 1, 2, 3 and 5 as defined by BARC', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'Comparison of target lesion failures', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'Patient-oriented composite endpoint (PoCE)', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years', 'description': 'Patient-oriented composite endpoint (PoCE) includes all-cause death, all MI, any revascularization, and stroke.'}, {'measure': 'Ischemic-driven target lesion revascularization (iTLR)', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'Ischemic-driven target vessel revascularization (iTVR)', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}, {'measure': 'All cardiac revascularization', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years', 'description': 'All cardiac revascularization includes PCI and CABG.'}, {'measure': 'Two types of stent thrombosis events as defined by BRS_ARC2', 'timeFrame': '30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Bioabsorbable Coronary Artery Rapamycin-eluting Stent System', 'Optimized Antiplatelet Therapy', 'Coronary Heart Disease', 'Randomized Controlled Trial'], 'conditions': ['Coronary Heart Disease']}, 'descriptionModule': {'briefSummary': 'This study is designed to verify the safety and efficacy of Lepu® NeoVas™ Bioabsorbable Coronary Artery Rapamycin-eluting Stent System combined with different antiplatelet therapies in the treatment of coronary heart disease.', 'detailedDescription': 'A total of 2150 subjects are planned to be enrolled in this trial. Subjects meeting the inclusion criteria and without exclusion criteria are implanted with NeoVas™ stents and randomly assigned to the experimental group and the control group in a 1:1 ratio. Patients in both groups will receive aspirin in combination with a P2Y12 receptor antagonist in the first year after PCI (either clopidogrel or ticagrelor will be selected by investigators according to the degree of ischemia). Aspirin will be discontinued one year after surgery and clopidogrel will be continued until 5 years after surgery in the experimental group. The control group will continue to take dual antiplatelet (DAPT) drugs, including aspirin and clopidogrel, for 2 more years; then aspirin will be used alone from the 4th year to the 5th year.\n\nSubjects will be followed up at 30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years after surgery to observe whether the net adverse clinical events (NACEs) and other end points occur or not.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age 18 or above, male or non-pregnant female.\n* Evidence of myocardial ischemia (e.g., stable angina, unstable angina, medium-low risk NSTEMI, STEMI with onset more than 1 week, old myocardial infarction or asymptomatic myocardial ischemia), and suitable for PCI surgery.\n* The target lesion is in-situ coronary artery lesion, the total length of single lesion is no more than 40mm (the total length of stent is no more than 48mm), and the diameter of the target lesion is between 2.75mm and 3.75mm (visual measurement).\n* The diameter stenosis of target lesion is ≥70% in visual (or ≥50% with clinical evidence of myocardial ischemia in that range), and the TIMI blood flow is greater than grade 1.\n* The stent with diameter more than 3.0mm is allowed to overlap with another stent once, the overlapping methods could be edge to edge or at most 1mm overlap. The total number of stents per patient is no more than 4, with a maximum of 2 stents per vessel (the 2.75mm diameter stent is not allowed to overlap).\n* Patient with indications for coronary artery bypass surgery.\n* Aspirin and clopidogrel could be used continuously during the study.\n* Patient who can understand the purpose of this trial, is willing to participate in the trial and to conduct clinical follow-up as required by the study protocol.\n\nExclusion Criteria:\n\n* Acute ST-segment elevation myocardial infarction within 1 week.\n* Left main coronary artery disease, branch vessel diameter≥2.0mm, three-vessel coronary artery disease and bridge vessel disease; visible thrombus in the target vessel.\n* Severe distortion, severe calcification that cannot be successfully predilated, and other lesions that are not suitable for stent delivery and deployment.\n* Intra-stent restenosis.\n* Severe heart failure (NYHA≥III or left ventricular ejection fraction\\<35%).\n* Severe renal insufficiency, eGFR\\<30ml/min/1.73m2 or serum creatinine\\>2.5mg/dL (221μmol/L).\n* Patients with bleeding tendency, active gastrointestinal ulcer, history of cerebral hemorrhage or subarachnoid hemorrhage, history of stroke within half a year, fundus hemorrhage affecting vision, antiplatelet agents and anticoagulant treatment contraindications who cannot receive antithrombotic therapy.\n* Patients requiring long-term oral anticoagulants during the study period.\n* Patients who are pregnant, breastfeeding, or planning to become pregnant during the study period.\n* Patients with malignancies, organ transplants, or drug addiction that can seriously affect study compliance.\n* Patients with contraindications to aspirin, clopidogrel or ticagrelor.\n* Known allergy to aspirin, clopidogrel, ticagrelor, heparin, contrast agent, polylactic acid polymer and rapamycin.\n* Thrombosis occurred during previous clopidogrel treatment.\n* Life expectancy is less than 36 months.\n* Participated in clinical trials of other drugs or medical devices before enrollment and failed to meet the time limit of the primary end point.\n* Patients who will have elective surgery within a year and need to discontinue aspirin, clopidogrel or ticagrelor.\n* Subjects are deemed unsuitable for enrollment by investigators.'}, 'identificationModule': {'nctId': 'NCT04995159', 'briefTitle': 'Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System', 'organization': {'class': 'INDUSTRY', 'fullName': 'Lepu Medical Technology (Beijing) Co., Ltd.'}, 'officialTitle': 'Evaluate the Safety and Efficacy of Optimized Antiplatelet Therapy in Patients With Coronary Heart Disease After Implantation of NeoVas™ Bioabsorbable Coronary Artery Rapamycin-eluting Stent System.', 'orgStudyIdInfo': {'id': 'OPT-BRS'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Poststent SAPT treatment cohort', 'description': 'receiving the treatment with NeoVas™ Bioabsorbable Coronary Artery Rapamycin-eluting Stent System of Lepu Medical combined with SAPT strategy', 'interventionNames': ['Drug: Single anti-platelet therapy']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Poststent DAPT treatment cohort', 'description': 'receiving the treatment with NeoVas™ Bioabsorbable Coronary Artery Rapamycin-eluting Stent System of Lepu Medical combined with DAPT strategy', 'interventionNames': ['Drug: Dual anti-platelet therapy']}], 'interventions': [{'name': 'Single anti-platelet therapy', 'type': 'DRUG', 'otherNames': ['SAPT strategy'], 'description': 'Aspirin in combination with a P2Y12 receptor antagonist (either clopidogrel or ticagrelor will be selected by investigators according to the degree of ischemia) in the first year after PCI. Aspirin will be discontinued one year after surgery and clopidogrel will be continued until 5 years after surgery.', 'armGroupLabels': ['Poststent SAPT treatment cohort']}, {'name': 'Dual anti-platelet therapy', 'type': 'DRUG', 'otherNames': ['DAPT strategy'], 'description': 'Aspirin in combination with a P2Y12 receptor antagonist (either clopidogrel or ticagrelor will be selected by investigators according to the degree of ischemia) in the first year after PCI. Patients continue to take dual antiplatelet (DAPT) drugs, including aspirin and clopidogrel, for 2 more years; then aspirin will be used alone from the 4th year to the 5th year.', 'armGroupLabels': ['Poststent DAPT treatment cohort']}]}, 'contactsLocationsModule': {'locations': [{'zip': '233099', 'city': 'Bengbu', 'state': 'Anhui', 'country': 'China', 'contacts': [{'name': 'Hongju Wang', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital of Bengbu Medical College', 'geoPoint': {'lat': 32.94083, 'lon': 117.36083}}, {'zip': '230022', 'city': 'Hefei', 'state': 'Anhui', 'country': 'China', 'contacts': [{'name': 'Xianhe Lin', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital with Anhui Medical University', 'geoPoint': {'lat': 31.86389, 'lon': 117.28083}}, {'zip': '241001', 'city': 'Wuhu', 'state': 'Anhui', 'country': 'China', 'contacts': [{'name': 'Shengxing Tang', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital of Wannan Medical College', 'geoPoint': {'lat': 31.35259, 'lon': 118.42947}}, {'zip': '100005', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Zhicheng Jing', 'role': 'CONTACT'}], 'facility': 'Peking Union Medical College Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '100020', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Lefeng Wang', 'role': 'CONTACT'}], 'facility': 'Beijing Chaoyang Hospital, Capital Medical University', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '100029', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Yujie Zhou', 'role': 'CONTACT'}], 'facility': 'Beijing Anzhen Hospital, Capital Medical University-12 Ward', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '100029', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Jinghua Liu', 'role': 'CONTACT'}], 'facility': 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'China', 'contacts': [{'name': 'Hengjian Hao', 'role': 'CONTACT'}], 'facility': 'Xuan Wu Hospital, Capital Medical University', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '100191', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Yida Tang', 'role': 'CONTACT'}], 'facility': 'Peking University Third Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '101199', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Jincheng Guo', 'role': 'CONTACT'}], 'facility': 'Beijing Luhe Hospital, Capital Medical University', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '102399', 'city': 'Beijing', 'state': 'Beijing Municipality', 'country': 'China', 'contacts': [{'name': 'Yu Wang', 'role': 'CONTACT'}], 'facility': 'Beijing Jingmei Group General Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}, {'zip': '400042', 'city': 'Chongqing', 'state': 'Chongqing Municipality', 'country': 'China', 'contacts': [{'name': 'Kanghua Ma', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital of Chongqing Medical University', 'geoPoint': {'lat': 29.56026, 'lon': 106.55771}}, {'zip': '400042', 'city': 'Chongqing', 'state': 'Chongqing Municipality', 'country': 'China', 'contacts': [{'name': 'Yuehui Yin', 'role': 'CONTACT'}], 'facility': 'The Second Affiliated Hospital of Chongqing Medical University', 'geoPoint': {'lat': 29.56026, 'lon': 106.55771}}, {'zip': '730000', 'city': 'Lanzhou', 'state': 'Gansu', 'country': 'China', 'contacts': [{'name': 'Ping Xie', 'role': 'CONTACT'}], 'facility': 'Gansu Provincial Hospital', 'geoPoint': {'lat': 36.05701, 'lon': 103.83987}}, {'zip': '730000', 'city': 'Lanzhou', 'state': 'Gansu', 'country': 'China', 'contacts': [{'name': 'Ming Bai', 'role': 'CONTACT'}], 'facility': 'The First Hospital of Lanzhou University', 'geoPoint': {'lat': 36.05701, 'lon': 103.83987}}, {'zip': '730099', 'city': 'Lanzhou', 'state': 'Gansu', 'country': 'China', 'contacts': [{'name': 'Xin Lin', 'role': 'CONTACT'}], 'facility': 'Lanzhou University Second Hospital', 'geoPoint': {'lat': 36.05701, 'lon': 103.83987}}, {'zip': '528000', 'city': 'Foshan', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Xili Yang', 'role': 'CONTACT'}], 'facility': "Foshan First People's Hospital", 'geoPoint': {'lat': 23.02677, 'lon': 113.13148}}, {'zip': '510000', 'city': 'Guangzhou', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Qiuxiong Chen', 'role': 'CONTACT'}], 'facility': 'Guangdong Provincial Hospital of Traditional Chinese Medicine', 'geoPoint': {'lat': 23.11667, 'lon': 113.25}}, {'zip': '510150', 'city': 'Guangzhou', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Ximing Chen', 'role': 'CONTACT'}], 'facility': 'The Third Affiliated Hospital of Guangdong Medical University', 'geoPoint': {'lat': 23.11667, 'lon': 113.25}}, {'zip': '515041', 'city': 'Shantou', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Zhixiong Cai', 'role': 'CONTACT'}], 'facility': 'Shantou Central Hospital', 'geoPoint': {'lat': 23.35489, 'lon': 116.67876}}, {'zip': '515041', 'city': 'Shantou', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Bin Wang', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital of Shantou University Medical College', 'geoPoint': {'lat': 23.35489, 'lon': 116.67876}}, {'zip': '515041', 'city': 'Shantou', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Jilin Li', 'role': 'CONTACT'}], 'facility': 'The Second Affiliated Hospital of Shantou University Medical College', 'geoPoint': {'lat': 23.35489, 'lon': 116.67876}}, {'zip': '518055', 'city': 'Shenzhen', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Haiying Li', 'role': 'CONTACT'}], 'facility': 'Shenzhen University General Hospital', 'geoPoint': {'lat': 22.54554, 'lon': 114.0683}}, {'zip': '524000', 'city': 'Zhanjiang', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Jie Chen', 'role': 'CONTACT'}], 'facility': "Zhanjiang Central People's Hospital", 'geoPoint': {'lat': 21.23391, 'lon': 110.38749}}, {'zip': '519000', 'city': 'Zhuhai', 'state': 'Guangdong', 'country': 'China', 'contacts': [{'name': 'Jian Chen', 'role': 'CONTACT'}], 'facility': 'The Fifth Affiliated Hospital of Sun Yat-sen University', 'geoPoint': {'lat': 22.27694, 'lon': 113.56778}}, {'zip': '541002', 'city': 'Guilin', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Yubin Wu', 'role': 'CONTACT'}], 'facility': "Guilin People's Hospital", 'geoPoint': {'lat': 25.28022, 'lon': 110.29639}}, {'zip': '545006', 'city': 'Liuchow', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Fangyong Jiang', 'role': 'CONTACT'}], 'facility': "Liuzhou People's Hospital", 'geoPoint': {'lat': 24.32405, 'lon': 109.40698}}, {'zip': '545006', 'city': 'Liuchow', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Hong Wang', 'role': 'CONTACT'}], 'facility': "Liuzhou Worker's Hospital", 'geoPoint': {'lat': 24.32405, 'lon': 109.40698}}, {'zip': '530021', 'city': 'Nanning', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Lang Li', 'role': 'CONTACT'}], 'facility': 'The First Affiliated Hospital of Guangxi Medical University', 'geoPoint': {'lat': 22.81667, 'lon': 108.31667}}, {'zip': '530022', 'city': 'Nanning', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Xianming Zhao', 'role': 'CONTACT'}], 'facility': "The First People's Hospital of Nanning", 'geoPoint': {'lat': 22.81667, 'lon': 108.31667}}, {'zip': '537099', 'city': 'Yulin', 'state': 'Guangxi', 'country': 'China', 'contacts': [{'name': 'Ping Li', 'role': 'CONTACT'}], 'facility': "Yulin First People's Hospital", 'geoPoint': {'lat': 22.6305, 'lon': 110.14686}}, {'zip': '550000', 'city': 'Guiyang', 'state': 'Guizhou', 'country': 'China', 'contacts': [{'name': 'Qiang Wu', 'role': 'CONTACT'}], 'facility': "Guizhou Provincial People's Hospital", 'geoPoint': {'lat': 26.58333, 'lon': 106.71667}}, {'zip': '570208', 'city': 'Haikou', 'state': 'Hainan', 'country': 'China', 'contacts': [{'name': 'Bo Xing', 'role': 'CONTACT'}], 'facility': "Haikou People's Hospital", 'geoPoint': {'lat': 20.03421, 'lon': 110.34651}}, {'zip': '570216', 'city': 'Haikou', 'state': 'Hainan', 'country': 'China', 'contacts': [{'name': 'Yuewu Chen', 'role': 'CONTACT'}], 'facility': 'The Second Affiliated Hospital of Hainan Medical University', 'geoPoint': {'lat': 20.03421, 'lon': 110.34651}}, {'zip': '571199', 'city': 'Sanya', 'state': 'Hainan', 'country': 'China', 'contacts': [{'name': 'Xiangqun Zhou', 'role': 'CONTACT'}], 'facility': "Sanya Central Hospital (Hainan Third People's Hospital)", 'geoPoint': {'lat': 18.25435, 'lon': 109.50947}}, {'zip': '061011', 'city': 'Cangzhou', 'state': 'Hebei', 'country': 'China', 'contacts': [{'name': 'Jun Zhang', 'role': 'CONTACT'}], 'facility': 'Cangzhou Central Hospital', 'geoPoint': {'lat': 38.31124, 'lon': 116.85334}}, {'zip': '053099', 'city': 'Hengshui', 'state': 'Hebei', 'country': 'China', 'contacts': [{'name': 'Qun Zheng', 'role': 'CONTACT'}], 'facility': "Hengshui People's Hospital", 'geoPoint': {'lat': 37.73908, 'lon': 115.68348}}, {'zip': '050057', 'city': 'Shijiazhuang', 'state': 'Hebei', 'country': 'China', 'contacts': [{'name': 'Xiaoyong Qi', 'role': 'CONTACT'}], 'facility': 'Hebei General Hospital', 'geoPoint': {'lat': 38.04139, 'lon': 114.47861}}, {'zip': '050082', 'city': 'Shijiazhuang', 'state': 'Hebei', 'country': 'China', 'contacts': [{'name': 'Leisheng Ru', 'role': 'CONTACT'}], 'facility': "the 980th Hospital of Chinese People's Liberation Army Joint Logistics Support Force", 'geoPoint': {'lat': 38.04139, 'lon': 114.47861}}, {'zip': '054001', 'city': 'Xingtai', 'state': 'Hebei', 'country': 'China', 'contacts': [{'name': 'Qingmin Wei', 'role': 'CONTACT'}], 'facility': "Xingtai People's Hospital", 'geoPoint': {'lat': 37.06217, 'lon': 114.49272}}, {'zip': '150001', 'city': 'Harbin', 'state': 'Heilongjiang', 'country': 'China', 'contacts': [{'name': 'Wei Yang', 'role': 'CONTACT'}], 'facility': 'The Fourth Hospital of Harbin Medical University', 'geoPoint': {'lat': 45.75, 'lon': 126.65}}, {'zip': '150086', 'city': 'Harbin', 'state': 'Heilongjiang', 'country': 'China', 'contacts': [{'name': 'Bo Yu', 'role': 'CONTACT'}], 'facility': 'The Second Hospital of Harbin Medical University', 'geoPoint': {'lat': 45.75, 'lon': 126.65}}, {'zip': '473005', 'city': 'Nanyang', 'state': 'Henan', 'country': 'China', 'contacts': [{'name': 'Gang Li', 'role': 'CONTACT'}], 'facility': 'Nanyang Central Hospital', 'geoPoint': {'lat': 32.99472, 'lon': 112.53278}}, {'zip': '473009', 'city': 'Nanyang', 'state': 'Henan', 'country': 'China', 'contacts': [{'name': 'Quanbao Shi', 'role': 'CONTACT'}], 'facility': 'Nanyang Second General Hospital', 'geoPoint': {'lat': 32.99472, 'lon': 112.53278}}, {'zip': '453099', 'city': 'Xinxiang', 'state': 'Henan', 'country': 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