Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D012141', 'term': 'Respiratory Tract Infections'}], 'ancestors': [{'id': 'D007239', 'term': 'Infections'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 702}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2006-12'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2009-01', 'completionDateStruct': {'date': '2007-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2009-01-27', 'studyFirstSubmitDate': '2009-01-21', 'studyFirstSubmitQcDate': '2009-01-21', 'lastUpdatePostDateStruct': {'date': '2009-01-28', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2009-01-22', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2007-06', 'type': 'ACTUAL'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['primary care', 'procalcitonin', 'acute respiratory tract infection'], 'conditions': ['Respiratory Tract Infections']}, 'referencesModule': {'references': [{'pmid': '20185423', 'type': 'DERIVED', 'citation': 'Burkhardt O, Ewig S, Haagen U, Giersdorf S, Hartmann O, Wegscheider K, Hummers-Pradier E, Welte T. Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection. Eur Respir J. 2010 Sep;36(3):601-7. doi: 10.1183/09031936.00163309. Epub 2010 Feb 25.'}]}, 'descriptionModule': {'briefSummary': 'Observation of the initial Procalcitonin values and the clinical course of consecutively included patients with Acute Respiratory Tract Infections at general medical practices in greater Hannover.', 'detailedDescription': 'Primary endpoint:\n\n* initial Procalcitonin values of patients with Acute Respiratory Tract Infections\n\nSecondary endpoints:\n\n* correlation of initial Procalcitonin values to classify Acute Respiratory Tract Infections\n* correlation of initial Procalcitonin values to subjective severity of Acute Respiratory Tract Infections\n* correlation of initial Procalcitonin values to antibiotic- prescriptions\n* correlation of initial Procalcitonin values to frequency of admission to hospital\n* correlation of initial Procalcitonin values to frequency of referrals (radiology, pneumology)'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'primary care patients in 45 practices in greater Hannover', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* written informed consent\n* all types of respiratory tract infection according to investigator´s diagnosis\n\nExclusion Criteria:\n\n* pretreatment with antibiotics in the past 2 weeks\n* portal hypertension\n* Major surgeries or multiple trauma which require hospitalization, in previous 4 weeks\n* Autoimmune disease and systemic diseases (lupus erythematodes, wegener´s disease)\n* Peritoneal dialysis\n* Acute treated or recently operated medullary c-cell-carcinoma, SCLC, carcinoid\n* Other inflammatory diseases (e.g. urinary tract infection, pyelonephritis, pancreatitis'}, 'identificationModule': {'nctId': 'NCT00827060', 'briefTitle': 'Observation of Initial Procalcitonin and the Clinical Course of Patients With Acute Respiratory Tract Infections', 'organization': {'class': 'OTHER', 'fullName': 'Hannover Medical School'}, 'officialTitle': 'Observation of the Initial Procalcitonin Values and the Clinical Course of Patients With Acute Respiratory Tract Infections at General Medical Practices in Greater Hannover', 'orgStudyIdInfo': {'id': 'HannoverPro'}}, 'contactsLocationsModule': {'locations': [{'zip': '30625', 'city': 'Hanover', 'country': 'Germany', 'facility': 'Medical School Hannover, Department Pneumology', 'geoPoint': {'lat': 52.37052, 'lon': 9.73322}}], 'overallOfficials': [{'name': 'Olaf Burkhardt, PD Dr. med.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Medical School Hannover'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Hannover Medical School', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Prof. Dr. med. Tobias Welte', 'oldOrganization': 'Prof. Dr. med. Tobias Welte'}}}}