Ignite Creation Date:
2025-12-25 @ 2:13 AM
Ignite Modification Date:
2025-12-26 @ 12:41 AM
Study NCT ID:
NCT00243360
Status:
COMPLETED
Last Update Posted:
2005-10-24
First Post:
2005-10-21
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Optimizing Antibiotic Use in Long Term Care
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D014552', 'term': 'Urinary Tract Infections'}], 'ancestors': [{'id': 'D007239', 'term': 'Infections'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'ECT', 'interventionModel': 'PARALLEL'}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2001-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2005-10', 'completionDateStruct': {'date': '2003-07'}, 'lastUpdateSubmitDate': '2005-10-21', 'studyFirstSubmitDate': '2005-10-21', 'studyFirstSubmitQcDate': '2005-10-21', 'lastUpdatePostDateStruct': {'date': '2005-10-24', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-10-24', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Antimicrobial prescriptions'}], 'secondaryOutcomes': [{'measure': 'Urinary cultures,'}, {'measure': 'hospitalizations, deaths'}]}, 'conditionsModule': {'keywords': ['Urinary tract infections,', 'antibiotic use,', 'long term care facilities'], 'conditions': ['Urinary Tract Infection, Antibiotic Use']}, 'descriptionModule': {'briefSummary': 'The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic prescribing for urinary indications in this population.', 'detailedDescription': 'Antibiotic use is intense in nursing homes and frequently inappropriate when prescribed for urinary indications. Evidence from randomized controlled trials suggests that treatment of asymptomatic bacteriuria, the presence of bacteria in the urine in the absence of urinary symptoms, is not beneficial. Despite this, one in three prescriptions for urinary indications are for asymptomatic bacteriuria. To improve antibiotic prescribing in this setting we conducted a cluster randomized trial of a strategy to implement diagnostic and treatment algorithms for urinary infection. 24 nursing homes were randomized to either the intervention (implemented at the nursing home level using a multi-faceted approach: small group interactive sessions for nurses, one-on-one interviews for physicians, videotapes, written material, and outreach visits) or to usual care.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'minimumAge': '0 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Individuals- all residents eligible\n2. Nursing homes\n\n * Free standing long term care facilities with \\>100 beds\n * No stated policy for diagnosis or treatment of urinary tract infections\n * The facility agrees to refrain from introducing new strategies for antibiotic utilization or clinical pathways during study\n\nExclusion Criteria:\n\n\\-'}, 'identificationModule': {'nctId': 'NCT00243360', 'briefTitle': 'Optimizing Antibiotic Use in Long Term Care', 'organization': {'class': 'FED', 'fullName': 'Agency for Healthcare Research and Quality (AHRQ)'}, 'officialTitle': 'Optimizing Antibiotic Use in Long Term Care', 'orgStudyIdInfo': {'id': 'U18HS011113-01', 'link': 'https://reporter.nih.gov/quickSearch/U18HS011113-01', 'type': 'AHRQ'}}, 'armsInterventionsModule': {'interventions': [{'name': 'diagnostic and treatment clinical algorithms', 'type': 'BEHAVIORAL'}]}, 'contactsLocationsModule': {'locations': [{'zip': 'L8N 3Z5', 'city': 'Hamilton', 'state': 'Ontario', 'country': 'Canada', 'facility': 'McMaster University', 'geoPoint': {'lat': 43.25011, 'lon': -79.84963}}], 'overallOfficials': [{'name': 'Mark B Loeb, MD MSc FRCPC', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'McMaster University'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Agency for Healthcare Research and Quality (AHRQ)', 'class': 'FED'}}}}