Ignite Creation Date:
2025-12-25 @ 2:07 AM
Ignite Modification Date:
2025-12-31 @ 9:50 PM
Study NCT ID:
NCT07016360
Status:
RECRUITING
Last Update Posted:
2025-06-11
First Post:
2025-05-21
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Comparison of Effectiveness of Topical Retinoids Versus Liquid Nitrogen in Treatment of Plantar Warts(Viral Infection)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D014860', 'term': 'Warts'}], 'ancestors': [{'id': 'D030361', 'term': 'Papillomavirus Infections'}, {'id': 'D004266', 'term': 'DNA Virus Infections'}, {'id': 'D014777', 'term': 'Virus Diseases'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D017193', 'term': 'Skin Diseases, Viral'}, {'id': 'D014412', 'term': 'Tumor Virus Infections'}, {'id': 'D012874', 'term': 'Skin Diseases, Infectious'}, {'id': 'D012871', 'term': 'Skin Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE4'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 98}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2025-06-15', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-06', 'completionDateStruct': {'date': '2025-12-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-06-03', 'studyFirstSubmitDate': '2025-05-21', 'studyFirstSubmitQcDate': '2025-06-03', 'lastUpdatePostDateStruct': {'date': '2025-06-11', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2025-06-11', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-12-31', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Efficacy of Treatment', 'timeFrame': '06 months', 'description': 'It will be defined through visual inspection by observing the complete clearance of the warts after 8 weeks administration of the treatment in both groups'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Plantar warts', 'Topical adapalene gel', 'Cryotherapy'], 'conditions': ['Viral Warts']}, 'descriptionModule': {'briefSummary': 'This is a comparative study between two treatment options for skin viral infection.', 'detailedDescription': 'This is a comparative study between two treatment for viral infection in epidermal layer of skin that proliferates slowly forming thick, growths. This study will compare and evaluate the differences in efficacy between topical liquid nitrogen and topical retinoids.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '60 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n\\-\n\nPatients age limit 18-60 Years Patients with either gender (Male/Female) Patients with recurrent plantar warts\n\nExclusion Criteria:\n\n* Pregnancy/lactation. Pt on topical or systemic therapy in last 6 months. On immunosuppressants. \\> 5 lesions. Pts with local secondary infections.'}, 'identificationModule': {'nctId': 'NCT07016360', 'briefTitle': 'Comparison of Effectiveness of Topical Retinoids Versus Liquid Nitrogen in Treatment of Plantar Warts(Viral Infection)', 'organization': {'class': 'OTHER', 'fullName': 'Khyber Teaching Hospital'}, 'officialTitle': 'Comparison of Efficacy of Topical Adapalene Gel Versus Cryotherapy in Recurrent Plantar Warts', 'orgStudyIdInfo': {'id': '192/DME/KMC'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'A', 'description': 'Treated with Topical adapalene gel 0.1%', 'interventionNames': ['Drug: Topical Adapalene Gel 0.1%']}, {'type': 'EXPERIMENTAL', 'label': 'B', 'description': 'Treated with liquid nitrogen over affected parts', 'interventionNames': ['Procedure: Topical Liquid Nitrogen application']}], 'interventions': [{'name': 'Topical Adapalene Gel 0.1%', 'type': 'DRUG', 'description': 'Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months', 'armGroupLabels': ['A']}, {'name': 'Topical Liquid Nitrogen application', 'type': 'PROCEDURE', 'description': 'Liquid Nitrogen will be applied to affected parts.', 'armGroupLabels': ['B']}]}, 'contactsLocationsModule': {'locations': [{'zip': '25000', 'city': 'Peshawar', 'state': 'Khyber Pakhtunkhwa', 'status': 'RECRUITING', 'country': 'Pakistan', 'facility': 'Khyber Teaching Hospital', 'geoPoint': {'lat': 34.008, 'lon': 71.57849}}], 'centralContacts': [{'name': 'Saba Naz, MBBS', 'role': 'CONTACT', 'email': 'sabikhattak477@gmail.com', 'phone': '+923209600115'}], 'overallOfficials': [{'name': 'Saba Naz, MBBS', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Khyber Teaching Hospital'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO', 'description': "Patient's confidentiality may be breached"}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Khyber Teaching Hospital', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'DOCTOR', 'investigatorFullName': 'Saba Naz', 'investigatorAffiliation': 'Khyber Teaching Hospital'}}}}