Ignite Creation Date:
2025-12-24 @ 2:16 PM
Ignite Modification Date:
2026-02-21 @ 11:36 PM
Study NCT ID:
NCT00664495
Status:
COMPLETED
Last Update Posted:
2008-04-23
First Post:
2008-04-21
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Reduction of Abdominal Obesity and Insulin Resistance in Women
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009765', 'term': 'Obesity'}, {'id': 'D009043', 'term': 'Motor Activity'}, {'id': 'D007333', 'term': 'Insulin Resistance'}], 'ancestors': [{'id': 'D050177', 'term': 'Overweight'}, {'id': 'D044343', 'term': 'Overnutrition'}, {'id': 'D009748', 'term': 'Nutrition Disorders'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D001835', 'term': 'Body Weight'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D001519', 'term': 'Behavior'}, {'id': 'D006946', 'term': 'Hyperinsulinism'}, {'id': 'D044882', 'term': 'Glucose Metabolism Disorders'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D004038', 'term': 'Diet, Reducing'}, {'id': 'D015444', 'term': 'Exercise'}], 'ancestors': [{'id': 'D004035', 'term': 'Diet Therapy'}, {'id': 'D044623', 'term': 'Nutrition Therapy'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D004032', 'term': 'Diet'}, {'id': 'D009747', 'term': 'Nutritional Physiological Phenomena'}, {'id': 'D000066888', 'term': 'Diet, Food, and Nutrition'}, {'id': 'D010829', 'term': 'Physiological Phenomena'}, {'id': 'D009043', 'term': 'Motor Activity'}, {'id': 'D009068', 'term': 'Movement'}, {'id': 'D009142', 'term': 'Musculoskeletal Physiological Phenomena'}, {'id': 'D055687', 'term': 'Musculoskeletal and Neural Physiological Phenomena'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '1999-04'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2008-04', 'completionDateStruct': {'date': '2003-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2008-04-22', 'studyFirstSubmitDate': '2008-04-21', 'studyFirstSubmitQcDate': '2008-04-22', 'lastUpdatePostDateStruct': {'date': '2008-04-23', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-04-23', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2003-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Abdominal Obesity', 'timeFrame': '4 months'}, {'measure': 'Insulin Resistance', 'timeFrame': '4 Months'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Obesity, exercise, diet, insulin resistance'], 'conditions': ['Obesity']}, 'referencesModule': {'references': [{'pmid': '15166299', 'type': 'RESULT', 'citation': 'Ross R, Janssen I, Dawson J, Kungl AM, Kuk JL, Wong SL, Nguyen-Duy TB, Lee S, Kilpatrick K, Hudson R. Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial. Obes Res. 2004 May;12(5):789-98. doi: 10.1038/oby.2004.95.'}]}, 'descriptionModule': {'briefSummary': 'The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '50 Years', 'minimumAge': '20 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Premenopausal women\n\nExclusion Criteria:\n\n* Smokers and diabetics'}, 'identificationModule': {'nctId': 'NCT00664495', 'briefTitle': 'Reduction of Abdominal Obesity and Insulin Resistance in Women', 'organization': {'class': 'OTHER', 'fullName': "Queen's University"}, 'officialTitle': 'Reduction of Abdominal Obesity and Insulin Resistance in Women', 'orgStudyIdInfo': {'id': 'Ross 1999'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'NO_INTERVENTION', 'label': 'C', 'description': 'Control'}, {'type': 'ACTIVE_COMPARATOR', 'label': 'DWL', 'description': 'Diet Weight Loss', 'interventionNames': ['Behavioral: Diet Weight Loss']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'EWL', 'description': 'Exercise Weight Loss', 'interventionNames': ['Behavioral: Exercise Weight Loss']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'EWS', 'description': 'Exercise Without Weight Loss', 'interventionNames': ['Behavioral: Exercise Without Weight Loss']}], 'interventions': [{'name': 'Diet Weight Loss', 'type': 'BEHAVIORAL', 'armGroupLabels': ['DWL']}, {'name': 'Exercise Weight Loss', 'type': 'BEHAVIORAL', 'armGroupLabels': ['EWL']}, {'name': 'Exercise Without Weight Loss', 'type': 'BEHAVIORAL', 'armGroupLabels': ['EWS']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'K7L 3N6', 'city': 'Kingston', 'state': 'Ontario', 'country': 'Canada', 'facility': "Queen's University", 'geoPoint': {'lat': 44.22976, 'lon': -76.48098}}], 'overallOfficials': [{'name': 'Robert Ross, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': "Queen's University"}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': "Queen's University", 'class': 'OTHER'}, 'collaborators': [{'name': 'Canadian Institutes of Health Research (CIHR)', 'class': 'OTHER_GOV'}], 'responsibleParty': {'oldNameTitle': "Queen's University"}}}}