Ignite Creation Date:
2025-12-25 @ 1:43 AM
Ignite Modification Date:
2025-12-26 @ 12:00 AM
Study NCT ID:
NCT00144794
Status:
RECRUITING
Last Update Posted:
2025-10-31
First Post:
2005-09-02
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Mucopolysaccharidosis I (MPS I) Registry
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24', 'removedCountries': ['United Arab Emirates']}, 'conditionBrowseModule': {'meshes': [{'id': 'D008059', 'term': 'Mucopolysaccharidosis I'}], 'ancestors': [{'id': 'D009083', 'term': 'Mucopolysaccharidoses'}, {'id': 'D002239', 'term': 'Carbohydrate Metabolism, Inborn Errors'}, {'id': 'D008661', 'term': 'Metabolism, Inborn Errors'}, {'id': 'D030342', 'term': 'Genetic Diseases, Inborn'}, {'id': 'D009358', 'term': 'Congenital, Hereditary, and Neonatal Diseases and Abnormalities'}, {'id': 'D016464', 'term': 'Lysosomal Storage Diseases'}, {'id': 'D017520', 'term': 'Mucinoses'}, {'id': 'D003240', 'term': 'Connective Tissue Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1500}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2003-11-20', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-10', 'completionDateStruct': {'date': '2034-01-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-10-30', 'studyFirstSubmitDate': '2005-09-02', 'studyFirstSubmitQcDate': '2005-09-02', 'lastUpdatePostDateStruct': {'date': '2025-10-31', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-09-05', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2034-01-31', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'To evaluate the long-term effectiveness of Aldurazyme', 'timeFrame': 'Approximately 17 Years'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ["Hurler's Syndrome", 'Hurler-Scheie Syndrome', 'Scheie Syndrome'], 'conditions': ['Mucopolysaccharidosis I (MPS I)']}, 'referencesModule': {'references': [{'pmid': '28892147', 'type': 'BACKGROUND', 'citation': 'Viskochil D, Muenzer J, Guffon N, Garin C, Munoz-Rojas MV, Moy KA, Hutchinson DT. Carpal tunnel syndrome in mucopolysaccharidosis I: a registry-based cohort study. Dev Med Child Neurol. 2017 Dec;59(12):1269-1275. doi: 10.1111/dmcn.13545. Epub 2017 Sep 11.'}, {'pmid': '25214650', 'type': 'BACKGROUND', 'citation': 'Arn P, Bruce IA, Wraith JE, Travers H, Fallet S. Airway-related symptoms and surgeries in patients with mucopolysaccharidosis I. Ann Otol Rhinol Laryngol. 2015 Mar;124(3):198-205. doi: 10.1177/0003489414550154. Epub 2014 Sep 11.'}, {'pmid': '24675674', 'type': 'BACKGROUND', 'citation': 'Beck M, Arn P, Giugliani R, Muenzer J, Okuyama T, Taylor J, Fallet S. The natural history of MPS I: global perspectives from the MPS I Registry. Genet Med. 2014 Oct;16(10):759-65. doi: 10.1038/gim.2014.25. Epub 2014 Mar 27.'}]}, 'descriptionModule': {'briefSummary': 'The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities.\n\nThe objectives of the Registry are:\n\n* To evaluate the long-term effectiveness and safety of Aldurazyme® (laronidase)\n* To characterize and describe the MPS I population as a whole, including the variability, progression, and natural history of MPS I\n* To help the MPS I medical community with the development of recommendations for monitoring patients and reports on patient outcomes to optimize patient care', 'detailedDescription': 'The MPS I Registry is an international program; in addition to the central contact information provided under the "Location" heading, patients may contact:\n\n* In Asia-Pacific - Vivian Liu, +65-6431-2548, Vivian.liu@genzyme.com\n* In Europe - +31-35-699-1232, europe@mpsiregistry.com\n* In Latin America - +617-591-5500, help@mpsiregistry.com\n* In North America - +617-591-5500, help@mpsiregistry.com'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'All Patients with MPS I', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* All patients with a confirmed diagnosis of MPS I are eligible for inclusion. Confirmed diagnosis is defined as: A. documented biochemical evidence of a deficiency in alpha (a)-L-iduronidase enzyme activity and/or B. mutation(s) in the gene coding for a-L-iduronidase, or measurable clinical signs and symptoms of MPS I\n* For all patients there should be a completed patient authorization form\n\nExclusion Criteria:\n\n* No exclusion criteria for participation in the MPS I Registry. NOTE: Registry participation does not exclude participation in other clinical studies.'}, 'identificationModule': {'nctId': 'NCT00144794', 'briefTitle': 'Mucopolysaccharidosis I (MPS I) Registry', 'organization': {'class': 'INDUSTRY', 'fullName': 'Sanofi'}, 'officialTitle': 'Mucopolysaccharidosis I (MPS I) Registry', 'orgStudyIdInfo': {'id': 'DIREGC07008'}, 'secondaryIdInfos': [{'id': 'U1111-1294-8266', 'type': 'REGISTRY', 'domain': 'ICTRP'}]}, 'contactsLocationsModule': {'locations': [{'zip': '85013', 'city': 'Phoenix', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Phoenix Children's Hospital- Site Number : 840003", 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '72202', 'city': 'Little Rock', 'state': 'Arkansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Arkansas Childrens Hospital- Site Number : 840109', 'geoPoint': {'lat': 34.74648, 'lon': -92.28959}}, {'zip': '90027', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Southern California Permanente Medical Group- Site Number : 840108', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90033', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'USC Health Sciences Center Dept of Genetics- Site Number : 840082', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '94609', 'city': 'Oakland', 'state': 'California', 'status': 'COMPLETED', 'country': 'United States', 'facility': "Children's Hospital Oakland- Site Number : 840029", 'geoPoint': {'lat': 37.80437, 'lon': -122.2708}}, {'zip': '92868', 'city': 'Orange', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of Orange County- Site Number : 840074", 'geoPoint': {'lat': 33.78779, 'lon': -117.85311}}, {'zip': '94305', 'city': 'Palo Alto', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Stanford Unviersity MC Dept of Genetics- Site Number : 840022', 'geoPoint': {'lat': 37.44188, 'lon': -122.14302}}, {'zip': '95817', 'city': 'Sacramento', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UC Davis MIND Institute- Site Number : 840010', 'geoPoint': {'lat': 38.58157, 'lon': -121.4944}}, {'zip': '92408', 'city': 'San Bernardino', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Loma Linda University Children's Hospital- Site Number : 840117", 'geoPoint': {'lat': 34.10834, 'lon': -117.28977}}, {'zip': '92093', 'city': 'San Diego', 'state': 'California', 'status': 'COMPLETED', 'country': 'United States', 'facility': 'University of California at San Diego- Site Number : 840007', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'city': 'San Francisco', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of California at San Francisco- Site Number : 840051', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}, {'zip': '80045', 'city': 'Aurora', 'state': 'Colorado', 'status': 'COMPLETED', 'country': 'United States', 'facility': "Children's Hospital Colorado - Aurora- Site Number : 840069", 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '80045', 'city': 'Aurora', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Colorado at Denver Genetics Site Number : 840068', 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '06520', 'city': 'New Haven', 'state': 'Connecticut', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Yale - Site Number : 840047', 'geoPoint': {'lat': 41.30815, 'lon': -72.92816}}, {'zip': '20010', 'city': 'Washington D.C.', 'state': 'District of Columbia', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's National Medical Center- Site Number : 840067", 'geoPoint': {'lat': 38.89511, 'lon': -77.03637}}, {'zip': '32610', 'city': 'Gainesville', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Florida Dept of Genetics- Site Number : 840083', 'geoPoint': {'lat': 29.65163, 'lon': -82.32483}}, {'zip': '32207', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Florida Pediatrics Genetics- Site Number : 840121', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '32216', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The Atwal Clinic- Site Number : 840112', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '33136', 'city': 'Miami', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University Of Miami SOM- Site Number : 840006', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33612', 'city': 'Tampa', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Pediatric Endocrine Associates- Site Number : 840017', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '30033', 'city': 'Decatur', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Emory University School of Medicine- Human Genetics- Site Number : 840060', 'geoPoint': {'lat': 33.77483, 'lon': -84.29631}}, {'zip': '60611', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Ann and Robert Lurie Children's Hospital- Site Number : 840011", 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60612', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Rush University Medical Center Genetics- Site Number : 840079', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '46202', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Indianapolis University School of Medicine- Site Number : 840027', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '52242', 'city': 'Iowa City', 'state': 'Iowa', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Iowa- Site Number : 840032', 'geoPoint': {'lat': 41.66113, 'lon': -91.53017}}, {'zip': '40202', 'city': 'Louisville', 'state': 'Kentucky', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Louisville- Genetics- Site Number : 840030', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '70121', 'city': 'New Orleans', 'state': 'Louisiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Ochsner Medical Center - Site Number : 840120', 'geoPoint': {'lat': 29.95465, 'lon': -90.07507}}, {'city': 'Baltimore', 'state': 'Maryland', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'John Hopkins- Site Number : 840044', 'geoPoint': {'lat': 39.29038, 'lon': -76.61219}}, {'zip': '02114', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Massachusetts General Hospital-Genetics- Site Number : 840062', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '2115', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Boston Children's Hospital - PIN- Site Number : 840093", 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '01199', 'city': 'Springfield', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Baystate Health- Site Number : 840002', 'geoPoint': {'lat': 42.10148, 'lon': -72.58981}}, {'zip': '48109', 'city': 'Ann Arbor', 'state': 'Michigan', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Michigan Pediatrics- Site Number : 840107', 'geoPoint': {'lat': 42.27756, 'lon': -83.74088}}, {'zip': '48201', 'city': 'Detroit', 'state': 'Michigan', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of Michigan- Site Number : 840066", 'geoPoint': {'lat': 42.33143, 'lon': -83.04575}}, {'zip': '55404', 'city': 'Minneapolis', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Health Care- Site Number : 840114", 'geoPoint': {'lat': 44.97997, 'lon': -93.26384}}, {'zip': '55455', 'city': 'Minneapolis', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Minnesota Medical Center Pediatrics- Site Number : 840076', 'geoPoint': {'lat': 44.97997, 'lon': -93.26384}}, {'zip': '63110', 'city': 'St Louis', 'state': 'Missouri', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Washington University of St. Louis- Site Number : 840100', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '68198', 'city': 'Omaha', 'state': 'Nebraska', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Nebraska Medical Center- Pediatrics- Site Number : 840084', 'geoPoint': {'lat': 41.25626, 'lon': -95.94043}}, {'zip': '89109', 'city': 'Las Vegas', 'state': 'Nevada', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Specialty Center of Nevada- Site Number : 840008", 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '07601', 'city': 'Hackensack', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Joseph M. Sanzari Children's Hospital- Site Number : 840101", 'geoPoint': {'lat': 40.88593, 'lon': -74.04347}}, {'zip': '07962', 'city': 'Morristown', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Atlantic Health System- Site Number : 840099', 'geoPoint': {'lat': 40.79677, 'lon': -74.48154}}, {'zip': '08901', 'city': 'New Brunswick', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'facility': "St. Peter's University Hospital- Site Number : 840016", 'geoPoint': {'lat': 40.48622, 'lon': -74.45182}}, {'zip': '07503', 'city': 'Paterson', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'facility': "St. Joseph's Children's Hospital- Site Number : 840057", 'geoPoint': {'lat': 40.91677, 'lon': -74.17181}}, {'zip': '11030', 'city': 'Manhasset', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Northwell Health- Site Number : 840102', 'geoPoint': {'lat': 40.79788, 'lon': -73.69957}}, {'zip': '10016', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'New York University School Of Medicine- Site Number : 840040', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10029-7494', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Metropolitan Hospital Center- Site Number : 840110', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '14642', 'city': 'Rochester', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Rochester Medical Center SOM- Site Number : 840105', 'geoPoint': {'lat': 43.15478, 'lon': -77.61556}}, {'zip': '13210', 'city': 'Syracuse', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'State University of New York- Site Number : 840052', 'geoPoint': {'lat': 43.04812, 'lon': -76.14742}}, {'zip': '27710', 'city': 'Durham', 'state': 'North Carolina', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Duke University Medical Center Genetics Dept- Site Number : 840037', 'geoPoint': {'lat': 35.99403, 'lon': -78.89862}}, {'city': 'Cincinnati', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Cincinnati Children's Hospital-Genetics- Site Number : 840041", 'geoPoint': {'lat': 39.12711, 'lon': -84.51439}}, {'zip': '44106', 'city': 'Cleveland', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University Hospitals Cleveland Medical Center- Site Number : 840119', 'geoPoint': {'lat': 41.4995, 'lon': -81.69541}}, {'zip': '43205-2664', 'city': 'Columbus', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Nationwide Children's Hospital - PIN- Site Number : 840091", 'geoPoint': {'lat': 39.96118, 'lon': -82.99879}}, {'zip': '43017', 'city': 'Dublin', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'LSD Data Registry Site LLC- Site Number : 840094', 'geoPoint': {'lat': 40.09923, 'lon': -83.11408}}, {'zip': '97239', 'city': 'Portland', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Oregon Health & Science University (OHSU)- Site Number : 840080', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '19104', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of Philadelphia HUP Medical Genetics- Site Number : 840089", 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'city': 'Philadelphia', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of Philadelphia- Site Number : 840034", 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '15224', 'city': 'Pittsburgh', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Pittsburgh- Site Number : 840023', 'geoPoint': {'lat': 40.44062, 'lon': -79.99589}}, {'zip': '02903', 'city': 'Providence', 'state': 'Rhode Island', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Rhode Island Hospital Genetics- Site Number : 840053', 'geoPoint': {'lat': 41.82399, 'lon': -71.41283}}, {'zip': '29605', 'city': 'Greenville', 'state': 'South Carolina', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Greenwood Genetcs- Site Number : 840055', 'geoPoint': {'lat': 34.85262, 'lon': -82.39401}}, {'zip': '75226', 'city': 'Dallas', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Baylor Research Center- Site Number : 840058', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '84132', 'city': 'Salt Lake City', 'state': 'Utah', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Utah Health Hospital- Site Number : 840092', 'geoPoint': {'lat': 40.76078, 'lon': -111.89105}}, {'zip': '22908', 'city': 'Charlottesville', 'state': 'Virginia', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Virginia School of Medicine-Pediatrics- Site Number : 840078', 'geoPoint': {'lat': 38.02931, 'lon': -78.47668}}, {'zip': '23507', 'city': 'Norfolk', 'state': 'Virginia', 'status': 'ACTIVE_NOT_RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of the Kings Daughters- Site Number : 840072", 'geoPoint': {'lat': 36.84681, 'lon': -76.28522}}, {'zip': '98105', 'city': 'Seattle', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Seattle Children's Hospital- Site Number : 840028", 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '98195', 'city': 'Seattle', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University Of Washington Medical Center- Site Number : 840059', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '98415', 'city': 'Tacoma', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Multicare Health System ¿ Mary Bridge Childrens Hospital- Site Number : 840115', 'geoPoint': {'lat': 47.25288, 'lon': -122.44429}}, {'zip': '53226', 'city': 'Milwaukee', 'state': 'Wisconsin', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Children's Hospital of Wisconsin-Pediatrics- Site Number : 840054", 'geoPoint': {'lat': 43.0389, 'lon': -87.90647}}, {'zip': '1425', 'city': 'Ciudad Autónoma de Buenos Aires', 'state': 'Buenos Aires', 'status': 'RECRUITING', 'country': 'Argentina', 'facility': 'Investigational Site Number : 153032'}, {'zip': '1629', 'city': 'Buenos Aires', 'status': 'RECRUITING', 'country': 'Argentina', 'facility': 'Investigational Site Number : 153130', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': '2145', 'city': 'Westmead', 'state': 'New South Wales', 'status': 'RECRUITING', 'country': 'Australia', 'facility': 'Investigational Site Number : 151069', 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