Ignite Creation Date:
2025-12-25 @ 1:33 AM
Ignite Modification Date:
2025-12-25 @ 11:46 PM
Study NCT ID:
NCT00374894
Status:
COMPLETED
Last Update Posted:
2006-09-12
First Post:
2006-09-11
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D007855', 'term': 'Lead Poisoning'}], 'ancestors': [{'id': 'D000075322', 'term': 'Heavy Metal Poisoning'}, {'id': 'D011041', 'term': 'Poisoning'}, {'id': 'D064419', 'term': 'Chemically-Induced Disorders'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D004113', 'term': 'Succimer'}], 'ancestors': [{'id': 'D013386', 'term': 'Succinates'}, {'id': 'D003998', 'term': 'Dicarboxylic Acids'}, {'id': 'D000144', 'term': 'Acids, Acyclic'}, {'id': 'D002264', 'term': 'Carboxylic Acids'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D013438', 'term': 'Sulfhydryl Compounds'}, {'id': 'D013457', 'term': 'Sulfur Compounds'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'DEFINED_POPULATION'}, 'enrollmentInfo': {'count': 500}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-03'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2004-04', 'completionDateStruct': {'date': '2004-08'}, 'lastUpdateSubmitDate': '2006-09-11', 'studyFirstSubmitDate': '2006-09-11', 'studyFirstSubmitQcDate': '2006-09-11', 'lastUpdatePostDateStruct': {'date': '2006-09-12', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2006-09-12', 'type': 'ESTIMATED'}}, 'conditionsModule': {'keywords': ['2,3-dimercaptosuccinic acid', 'Blood Lead Levels', 'children', 'multi-nutrients'], 'conditions': ['Lead Poisoning']}, 'referencesModule': {'references': [{'type': 'RESULT', 'citation': 'CDC．Preventing lead poisoning in young children［R］. U.D.Dept of health and Human services 1991:1.'}]}, 'descriptionModule': {'briefSummary': 'Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD'], 'maximumAge': '6 Years', 'minimumAge': '3 Years', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Initial BLLs 100-440µg/L\n* Age 3-6y\n* No more than two main residences\n* House cleaned (no lead contaminated)\n* Normal intake history and physical\n\nExclusion Criteria:\n\n* Chelation in the past 12 weeks\n* Concomitant Fe deficiency(ferritin\\<16ng/ml)\n* Hemoglobin\\<10.5g/dL\n* Medications affecting mineral metabolism'}, 'identificationModule': {'nctId': 'NCT00374894', 'briefTitle': 'The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning', 'organization': {'class': 'OTHER', 'fullName': 'China Medical University, China'}, 'orgStudyIdInfo': {'id': '20032063 - 2001102049'}}, 'armsInterventionsModule': {'interventions': [{'name': '2,3-dimercaptosuccinic acid', 'type': 'DRUG'}]}, 'contactsLocationsModule': {'locations': [{'zip': '110001', 'city': 'Shenyang', 'state': 'Liaoning', 'country': 'China', 'facility': 'China Medical University', 'geoPoint': {'lat': 41.79222, 'lon': 123.43278}}], 'overallOfficials': [{'name': 'Jin Ya ping, professor', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Department of Environmental and Occupational Health'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'China Medical University, China', 'class': 'OTHER'}}}}