Ignite Creation Date:
2025-12-25 @ 1:26 AM
Ignite Modification Date:
2026-03-02 @ 4:22 PM
Study NCT ID:
NCT03332693
Status:
UNKNOWN
Last Update Posted:
2017-11-06
First Post:
2017-11-02
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Macroscopic and Molecular Changes in Knee Muscular - Tendon Unit in Response to Acute Resistant Load
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D015444', 'term': 'Exercise'}], 'ancestors': [{'id': 'D009043', 'term': 'Motor Activity'}, {'id': 'D009068', 'term': 'Movement'}, {'id': 'D009142', 'term': 'Musculoskeletal Physiological Phenomena'}, {'id': 'D055687', 'term': 'Musculoskeletal and Neural Physiological Phenomena'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 300}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2017-11', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2017-11', 'completionDateStruct': {'date': '2019-11', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2017-11-02', 'studyFirstSubmitDate': '2017-11-02', 'studyFirstSubmitQcDate': '2017-11-02', 'lastUpdatePostDateStruct': {'date': '2017-11-06', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-11-06', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-11', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Genetic polymorphism changes in knee muscles', 'timeFrame': 'One year', 'description': 'Genetic analysis will be made through a blood test and biopsy of knee muscle and results will be compared'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Physical Exertion']}, 'descriptionModule': {'briefSummary': 'The aim of this study is to determine whether individuals differ one from the other in their genetic, cellular, systemic, structural and functional response to acute exercise.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '30 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Healthy adults\n\nExclusion Criteria:\n\n* Unhealthy adults'}, 'identificationModule': {'nctId': 'NCT03332693', 'briefTitle': 'Macroscopic and Molecular Changes in Knee Muscular - Tendon Unit in Response to Acute Resistant Load', 'organization': {'class': 'OTHER_GOV', 'fullName': 'Hillel Yaffe Medical Center'}, 'officialTitle': 'Macroscopic and Molecular Changes in Knee Muscular - Tendon Unit in Response to Acute Resistant Load', 'orgStudyIdInfo': {'id': 'HYMC-0058-16'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'No exercise', 'description': 'Volunteers will not participate in exercise', 'interventionNames': ['Other: No exercise']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Light exercise', 'description': 'Volunteers will participate in one short exercise', 'interventionNames': ['Other: Exercise']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Heavy exercise', 'description': 'Volunteers will participate in heavy exercise', 'interventionNames': ['Other: Exercise']}], 'interventions': [{'name': 'Exercise', 'type': 'OTHER', 'description': 'Leg weight raising', 'armGroupLabels': ['Heavy exercise', 'Light exercise']}, {'name': 'No exercise', 'type': 'OTHER', 'description': 'Volunteers will not participate in exercise', 'armGroupLabels': ['No exercise']}]}, 'contactsLocationsModule': {'locations': [{'zip': '38100', 'city': 'Hadera', 'country': 'Israel', 'contacts': [{'name': 'Eias Kassem, MD', 'role': 'CONTACT', 'email': 'eiask@hy.health.gov.il', 'phone': '972-50-6246882'}], 'facility': 'Hillel Yaffe Medical Center', 'geoPoint': {'lat': 32.44192, 'lon': 34.9039}}], 'centralContacts': [{'name': 'Eias Kassem, MD', 'role': 'CONTACT', 'email': 'eiask@hy.health.gov.il', 'phone': '972-6246882'}], 'overallOfficials': [{'name': 'Eias Kassem, MD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Hillel Yaffe Medical Center'}, {'name': 'Sigal Ben Zaken, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Wingate Academic College for Physical Education and Sport Sciences'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Hillel Yaffe Medical Center', 'class': 'OTHER_GOV'}, 'responsibleParty': {'type': 'SPONSOR'}}}}