Ignite Creation Date:
2024-05-05 @ 10:54 PM
Last Modification Date:
2024-10-26 @ 10:26 AM
Study NCT ID:
NCT01215487
Status:
COMPLETED
Last Update Posted:
2021-04-30
First Post:
2010-10-04
Brief Title:
A Study Investigating the Predictive Value of Philadelphia Positive Stem Cell Properties in Newly Diagnosed Patients With Chronic Myeloid Leukemia in Chronic Phase Receiving Treatment With Imatinib
Sponsor:
Organization:
University of British Columbia
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
None
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
Specimens of whole blood will be collected and used for measurement of sensitivity of the patients individual pretreatment colony-forming cells CFCs to IM exposure in vitro the level of expression of BCR-ABL OCT1 ABCB1MDR and ABCG2 transcripts in their CD34 cells and the frequency of mutant BCR-ABL transcripts in the same cells The cells are cultured for 3 weeks
Enrollment Count:
68
Enrollment Type:
ACTUAL
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Case-Only |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 12425 |
Who Masked List: