Ignite Creation Date:
2024-05-05 @ 7:07 PM
Last Modification Date:
2024-10-26 @ 9:42 AM
Study NCT ID:
NCT00600392
Status:
COMPLETED
Last Update Posted:
2016-01-20
First Post:
2008-01-15
Brief Title:
DNARNA Analysis of Blood and Skeletal Muscle in Patients Undergoing Cardiac Resynchronization Therapy CRT
Sponsor:
Organization:
Duke University
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
False
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
Serum TNF alpha IL-1 IL6 CRP uric acid albumin BNP IGF-1 and growth hormone at baseline and at 6 months
50 ml of blood will be collected at baseline and at 6 months It will be divided into aliquots as follows 10 ml in Pax-gene tubes for mRNA extraction 20 ml for various other biomarkers 10 ml for proteomics and 10 ml will be stored for any future use
Approximately a 5x5 - 7x7mm muscle biopsy will be obtained from the mid thigh region of each subject at baseline and at six months
Enrollment Count:
30
Enrollment Type:
ACTUAL
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Cohort |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 4752 |
Who Masked List: