Ignite Creation Date:
2024-05-06 @ 6:37 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05727982
Status:
RECRUITING
Last Update Posted:
2023-02-14
First Post:
2023-02-02
Brief Title:
Identification of Molecular Mechanisms of Coronary Instability in Homogeneous Subsets of Patients With Acute Coronary Syndromes for the Implementation of Precision Medicine
Sponsor:
Organization:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
True
Target Duration:
3 Years
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
Stool sample for the study of the composition of the intestinal bacterial flora microbiota faeces sample can also be collected at home keeping it at 4C Such sample must be transported cold 4C and delivered to the staff within 24 hours polyclinic
A venous blood sample of 18cc which will be used to evaluate 1 the inflammatory profile systemically by measuring the following plasma biomarkers zonulin C-reactive protein IL-1 IL-1Ra IL-5 IL-6 IL-7 IL-8 IL-9 IL-12 IL-17 IFN-γ MIP-1b VEGF MCP-1 and IL-8 IL-10 TNF- a TGF-b LPS 2 plasma metabolites
Enrollment Count:
400
Enrollment Type:
ESTIMATED
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Case-Control |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 92607 |
Who Masked List: