Ignite Creation Date:
2024-05-06 @ 3:12 PM
Last Modification Date:
2024-10-26 @ 1:45 PM
Study NCT ID:
NCT04553185
Status:
RECRUITING
Last Update Posted:
2023-12-01
First Post:
2020-08-26
Brief Title:
Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinsons Disease
Sponsor:
Organization:
University of Exeter
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
False
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
A venous sample will be collected from all participants The venous sample will serve for genetic testing for Single Nucleotide Polymorphisms in the Aquaporin-4 gene and genetic testing for mutations in the following Parkinsons disease-related genes SNCA LRRK2 VPS35 PARK2 PINK1 DJ-1 SYNJ1 DNAJ6 FBXO7 PLA2G6 LRP10 GBA and MAPT in a cohort of PD patients as well as for the determination in the blood of the levels of the following substances α-synuclein total and oligofragmented S100β LRP1 and ABCB1
Enrollment Count:
800
Enrollment Type:
ESTIMATED
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Cohort |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 68473 |
Who Masked List: