Ignite Creation Date:
2024-05-06 @ 1:55 PM
Last Modification Date:
2024-10-26 @ 1:22 PM
Study NCT ID:
NCT04160507
Status:
RECRUITING
Last Update Posted:
2024-02-29
First Post:
2019-11-08
Brief Title:
Duke APOL1 Research Biorepository
Sponsor:
Organization:
Duke University
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
False
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
Peripheral blood mononuclear cells PBMCs will be isolated from the blood using standard Ficoll-Paque technique A fraction of the PBMCs will be cryopreserved and stored at for future analysis We will submit a separate IRB protocol for use of future unspecified research with these samples The remaining fraction of PBMCs will be used to generate inducible pluripotentent stem cells iPSCs These iPSC would be differentiated into kidney cells which could then be further studied While no plans exist to immortalize any of these cell lines the consent form does allow for creating immortalized cell lines in the future Residual plasma will also be stored separately for additional analysis Kidney cells shed into urine would also be a potential source of iPSCs
Enrollment Count:
200
Enrollment Type:
ESTIMATED
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Other |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 60136 |
Who Masked List: