Ignite Creation Date:
2024-05-06 @ 1:39 PM
Last Modification Date:
2024-10-26 @ 1:17 PM
Study NCT ID:
NCT04086537
Status:
COMPLETED
Last Update Posted:
2021-04-29
First Post:
2019-09-09
Brief Title:
BMPR2 Mutations and Iron Metabolism in Pulmonary Arterial Hypertension
Sponsor:
Organization:
Heidelberg University
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
False
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITHOUT_DNA
Bio Spec Description:
Routine clinical laboratory investigations Iron metabolismHepcidin iron ferritin interleukin 6 transferrin circulating soluble transferrin receptor levels HematologyLeucocytes erythrocytes hemoglobin hematocrit platelets Substrates Bilirubin cholesterol triglycerides creatinine uric acid urea total protein albumin glucose ElectrolytesSodium potassium calcium chloride Enzymesserum glutamate oxaloacetate transaminase SGOT serum glutamate pyruvate transaminase SGPT Gamma-GT Glutamate Dehydrogenase GLDH alkaline phosphatase AP lactate dehydrogenase LDH creatine kinase CK Othersinternational normalized Ratio INR partial thromboplastin time PTT BiomarkersC-reactive Protein CRP NT-proBNP BMPR2 expression with real time quantitative polymerase chain reaction qPCR RNA extraction with Quiacube cDNA production using Transcriptor First Strand cDNA Synthesis Kit Laboratory assessments will be determined locally on-site
Enrollment Count:
109
Enrollment Type:
ACTUAL
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Other |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 58630 |
Who Masked List: