Ignite Creation Date:
2024-05-06 @ 12:20 AM
Last Modification Date:
2024-10-26 @ 10:48 AM
Study NCT ID:
NCT01558570
Status:
COMPLETED
Last Update Posted:
2019-09-26
First Post:
2011-09-12
Brief Title:
Intracellular Tight Junction Permeability in Schizophrenia Focus on Zonulin
Sponsor:
Organization:
University of Maryland Baltimore
Study Design
Study Type:
OBSERVATIONAL
Expanded Access Type Individual:
None
Expanded Access Type Intermediate:
None
Expanded Access Type Treatment:
None
Patient Registry:
None
Target Duration:
None
Design Allocation:
Design Intervention Model:
Design Intervention Model Description:
Design Masking Description:
Bio Spec Retention:
SAMPLES_WITH_DNA
Bio Spec Description:
Laboratory Measures
Zonulin and gliadin antibodies will be sent to the lab of Dr Alessio Fasano for assay
Genetic and Biochemical analysis will be sent for analysis and storage of blood sample at the Maryland Psychiatric Research Center Neurogenetics laboratory under the direction of Dr Ikwunga Wonodi Analysis will include kynurenic acid metabolites inflammatory markers from Peripheral Blood Mononuclear Cells PBMC and future genetic analysis including but not limited to human leukocyte antigen HLA haplotypes DQ2 and DQ8
Cytokines will be analyzed by the Cytokine Core Laboratory at the University of Maryland using Luminex Technology
Other standard laboratories will be done by Lab Corp or other contract laboratory
Enrollment Count:
100
Enrollment Type:
ACTUAL
Design Primary Purpose:
Design Masking:
Phases:
Observational Models:
| Name |
|---|
| Case-Only |
Time Perspective List:
Clinical Trial Statuses
| Name |
|---|
| 17285 |
Who Masked List: