Ignite Creation Date:
2025-12-25 @ 2:32 AM
Ignite Modification Date:
2026-02-21 @ 9:25 PM
Study NCT ID:
NCT03728634
Status:
COMPLETED
Last Update Posted:
2022-12-19
First Post:
2018-10-31
Is Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Evaluate the Safety and Tolerability, as Well as the Pharmacokinetic and Pharmacodynamic Profiles of Single and Multiple Doses of Eplontersen Administered Subcutaneously to Healthy Volunteers and Patients With Hereditary Transthyretin-Mediated Amyloidosis (hATTR ).
Sponsor:
Ionis Pharmaceuticals, Inc.
Organization:
Key Dates - Follows AllAPIJSON File Order
Start Date:
2018-12-21
Start Date Type:
ACTUAL
Primary Completion Date:
2020-02-20
Primary Completion Date Type:
ACTUAL
Completion Date:
2020-02-20
Completion Date Type:
ACTUAL
First Submit Date:
2018-10-31
First Submit QC Date:
None
Study First Post Date:
2018-11-02
Study First Post Date Type:
ACTUAL
Results First Submit Date:
2022-10-12
Results First Submit QC Date:
None
Results First Post Date:
2022-12-19
Results First Post Date Type:
ACTUAL
Results First Post QC Date:
None
Results First Post QC Date Type:
None
Disp First Submit Date:
None
Disp First Submit QC Date:
None
Disp First Post Date:
None
Disp First Post Date Type:
None
Last Update Submit Date:
2022-11-23
Last Update Post Date:
2022-12-19
Last Update Post Date Type:
ACTUAL