Ignite Creation Date:
2025-12-25 @ 12:41 AM
Ignite Modification Date:
2026-02-25 @ 5:25 PM
Study NCT ID:
NCT02568267
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2025-12-04
First Post:
2015-10-02
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Sponsor:
Hoffmann-La Roche
Organization:
Conditions & Keywords Data
Conditions:
Conditions
| Condition Brief | Condition Text | View |
|---|---|---|
| None | Breast Cancer | View |
| None | Cholangiocarcinoma | View |
| None | Colorectal Cancer | View |
| None | Head and Neck Neoplasms | View |
| None | Lymphoma, Large-Cell, Anaplastic | View |
| None | Melanoma | View |
| None | Neuroendocrine Tumors | View |
| None | Non-Small Cell Lung Cancer | View |
| None | Ovarian Cancer | View |
| None | Pancreatic Cancer | View |
| None | Papillary Thyroid Cancer | View |
| None | Primary Brain Tumors | View |
| None | Renal Cell Carcinoma | View |
| None | Sarcomas | View |
| None | Salivary Gland Cancers | View |
| None | Adult Solid Tumor | View |
Keywords:
Keywords
| Keyword Brief | Keyword Text | View |
|---|---|---|
| None | Entrectinib | View |
| None | RXDX-101 | View |
| None | TrkA | View |
| None | TrkB | View |
| None | TrkC | View |
| None | NTRK1 | View |
| None | NTRK2 | View |
| None | NTRK3 | View |
| None | ROS1 | View |
| None | ALK | View |
| None | Trk Fusions | View |
| None | NTRK Gene Rearrangements | View |
| None | ROS1 Fusions | View |
| None | ROS1 Gene Rearrangements | View |
| None | ALK Fusions | View |
| None | ALK Gene Rearrangements | View |
| None | Basket study | View |
| None | Non-small cell lung cancer | View |
| None | Colorectal cancer | View |
| None | Salivary gland cancers | View |
| None | Primary brain tumors | View |
| None | Melanoma | View |
| None | Sarcomas | View |
| None | Papillary thyroid cancer | View |
| None | Renal cell cancer | View |
| None | Pancreatic cancer | View |
| None | Breast cancer | View |
| None | Cholangiocarcinoma | View |
| None | Head & Neck cancers | View |
| None | Ovarian cancer | View |
| None | Neuroendocrine tumors | View |