Viewing Study NCT05378204

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Ignite Creation Date: 2025-12-24 @ 7:56 PM
Ignite Modification Date: 2026-01-22 @ 11:19 AM
Study NCT ID: NCT05378204
Status: RECRUITING
Last Update Posted: 2025-08-12
First Post: 2022-05-11
Is Gene Therapy: True
Has Adverse Events: False
Brief Title: Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.
Sponsor: Institut Claudius Regaud
Organization:
Overview Dates Organization Conditions Design Enrollment Locations Outcomes Modules Raw JSON

Conditions & Keywords Data

Conditions:

Conditions

Condition Brief Condition Text View
None Breast Cancer View
Keywords:

Keywords

Keyword Brief Keyword Text View
None Breast cancer View
None Germline BRCA mutation View
None PARP inhibitor View
None Biomarkers View
None POLQ View
None Polθ View
None Shieldin complex View
None 53BP1 View