Ignite Creation Date:
2024-05-05 @ 11:32 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00076258
Status:
COMPLETED
Last Update Posted:
2020-09-23
First Post:
2004-01-16
Brief Title:
Adding Exercise to Antidepressant Medication Treatment for Depression
Sponsor:
University of Texas Southwestern Medical Center
Organization:
University of Texas Southwestern Medical Center
Study Overview
Official Title:
Treatment With Exercise Augmentation for Depression TREAD
Status:
COMPLETED
Status Verified Date:
2020-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TREAD
Brief Summary:
This study will assess the effectiveness of an exercise program in improving antidepressant medication treatment for individuals with major depressive disorder MDD
Detailed Description:
Partial response to antidepressant treatment is common in people with MDD and is associated with significant morbidity and reduced quality of life Pharmacological therapies have been used to augment the effect of antidepressants however such therapies are associated with a range of adverse effects Studies indicate that exercise may be safe and effective in augmenting depression treatment This study will determine whether exercise can complement selective serotonin reuptake inhibitor SSRI therapy in people with MDD who have residual symptoms of depression despite drug treatment
Participants will be randomly assigned to either high frequency exercise or low frequency exercise for 12 weeks Depression symptoms will be measured weekly Quality of life and satisfaction with the study will also be measured Depression scales and self-reports will be used to assess participants
Participants will be randomly assigned to either high frequency exercise or low frequency exercise for 12 weeks Depression symptoms will be measured weekly Quality of life and satisfaction with the study will also be measured Depression scales and self-reports will be used to assess participants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01MH067692-01 | NIH | None | httpsreporternihgovquickSearchR01MH067692-01 |