Ignite Creation Date:
2024-05-05 @ 11:08 PM
Last Modification Date:
2024-10-26 @ 10:29 AM
Study NCT ID:
NCT01263964
Status:
COMPLETED
Last Update Posted:
2014-07-21
First Post:
2010-12-20
Brief Title:
Troponin Elevation in Acute Ischemic Stroke TRELAS
Sponsor:
Charite University Berlin Germany
Organization:
Charite University Berlin Germany
Study Overview
Official Title:
Troponin Elevation in Acute Ischemic Stroke TRELAS - a Prospective Study on the Frequency and Correlation to Coronary Artery Disease and to Stroke Localisation
Status:
COMPLETED
Status Verified Date:
2014-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TRELAS
Brief Summary:
The primary objective of the prospective observational trial TRELAS TRoponin ELevation in Acute ischemic Stroke is to elucidate the underlying pathomechanism of cTnT elevation in acute ischemic stroke Consecutive patients with acute ischemic stroke admitted to the Department of Neurology Campus Benjamin Franklin of the university hospital Charité will be screened for cTnT elevations suggestive of myocardial infarction 005 µgl Patients with increased troponin will undergo diagnostic coronary angiography within 72 hours Diagnostic findings of coronary angiographies taken out in age- and gender-matched patients presenting with NSTE-ACS Non-ST-Elevation Acute Coronary Syndrome to the Division of Cardiology will serve as a control The primary endpoint of the study will be the occurrence of culprit lesions indicating focal cardiac damage on the basis of an acute CAD
Detailed Description:
The primary objective of the prospective observational trial TRELAS TRoponin ELevation in Acute ischemic Stroke is to elucidate the underlying pathomechanism of cTnT elevation in acute ischemic stroke in order to give guidance for clinical practise All consecutive patients with acute MRI- or CT-confirmed ischemic stroke admitting within 72 hours after symptom onset to the Department of Neurology Campus Benjamin Franklin of the university hospital of the Charité will be screened for cTnT elevations suggestive of myocardial infarction 005 µgl on admission and day 2 Patients with increased troponin will undergo diagnostic coronary angiography within 72 hours Diagnostic findings of coronary angiographies taken out in age- and gender-matched patients presenting with NSTE-ACS Non-ST-Elevation Acute Coronary Syndrome to the Division of Cardiology will serve as a control The primary endpoint of the study will be the occurrence of angiographic culprit lesions indicating focal cardiac damage on the basis of an acute CAD Secondary endpoints will be the localisation of stroke in the cerebral imaging and ventriculographic findings of wall motion abnormalities suggestive of neurally mediated global cardiac dysfunction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 01 EO 0801 | OTHER_GRANT | German Ministry of Research and Education | None |