Ignite Creation Date:
2025-12-25 @ 1:17 AM
Ignite Modification Date:
2025-12-25 @ 11:26 PM
Study NCT ID:
NCT07064993
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2025-11-21
First Post:
2025-02-10
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Intraoperative and Postoperative Effects of Tramadol and Dexamethasone Added to Washing Solution in Knee Arthroscopies
Sponsor:
Yuzuncu Yil University
Organization:
Study Overview
Official Title:
Intraoperative and Postoperative Effects of Tramadol and Dexamethasone Added to Washing Solution in Knee Arthroscopies
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2025-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the effects of tramadol and dexamethasone added to washing solutions on postoperative nausea and vomiting, VAS score, itching and chills in knee arthroscopy cases.
Randomised, double-blind, prospective, clinical trial
Research Question(s):
1. Do tramadol and dexamethasone added to the washing solution have any effect on postoperative parameters in knee arthroscopy cases?
2. Does the postoperative efficacy change depending on the dose of tramadol and dexamethasone in the washing solution?
Translated with DeepL.com (free version)
Randomised, double-blind, prospective, clinical trial
Research Question(s):
1. Do tramadol and dexamethasone added to the washing solution have any effect on postoperative parameters in knee arthroscopy cases?
2. Does the postoperative efficacy change depending on the dose of tramadol and dexamethasone in the washing solution?
Translated with DeepL.com (free version)
Detailed Description:
Knee arthroscopy is a minimal surgical treatment method that allows closed intervention under anaesthesia for the diagnosis and treatment of joint disorders. The natural structure of the joints is preserved as much as possible and no unnecessary tissue damage is caused. The most important advantage is the possibility to reach every part of the joint and provide complete treatment.The aim of the study was to evaluate the effects of tramadol and dexamethasone added to washing solutions on postoperative nausea and vomiting, VAS score, itching and chills in knee arthroscopy cases.
Patients who are decided to undergo knee arthroscopy will be evaluated preoperatively by the anaesthesia outpatient clinic. Necessary information will be given and consent will be obtained. Patients will be randomised into 2 groups as study (S) and control (C) groups.
Study Group (Group S): 100 mg tramadol + 8 mg dexamethasone will be added to each 1000cc washing solution.
(tramadol max iv dose: 400 mg/day) (Dexamethasone max iv dose: 32mg/day) No any drugs will be used for control group solution For postoperative analgesia, 15mg/kg paracetamol iv will be administered to both groups as standard before extubation. The moment of being admitted to the PACU and having a RAMSAY sedation scale of 3 or less will be accepted as hour 0; 0, 3 and 6 hours VAS, nausea, vomiting, itching and chills will be evaluated.
Patients who are decided to undergo knee arthroscopy will be evaluated preoperatively by the anaesthesia outpatient clinic. Necessary information will be given and consent will be obtained. Patients will be randomised into 2 groups as study (S) and control (C) groups.
Study Group (Group S): 100 mg tramadol + 8 mg dexamethasone will be added to each 1000cc washing solution.
(tramadol max iv dose: 400 mg/day) (Dexamethasone max iv dose: 32mg/day) No any drugs will be used for control group solution For postoperative analgesia, 15mg/kg paracetamol iv will be administered to both groups as standard before extubation. The moment of being admitted to the PACU and having a RAMSAY sedation scale of 3 or less will be accepted as hour 0; 0, 3 and 6 hours VAS, nausea, vomiting, itching and chills will be evaluated.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?: