Ignite Creation Date:
2024-05-05 @ 11:03 PM
Last Modification Date:
2024-10-26 @ 10:28 AM
Study NCT ID:
NCT01249287
Status:
UNKNOWN
Last Update Posted:
2010-11-29
First Post:
2010-11-25
Brief Title:
FMRI in Monitoring Intracerebral Stem Cell Implantation for Chronic Stroke Patients
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2010-11
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A growing number of studies highlight the potential of stem cell transplantation as a novel therapeutic approach for stroke in animal model But the stem cell therapy for chronic stroke patients has not been well investigated yet In this study the investigators will test the hypothesis that intracerebral peripheral blood hematopoietic stem cell CD34 PBSC transplantation induces neuroplasticity in chronic stroke patients The remyelination of corticospinal tract in the lesion side focal increased perfusion and increased cortical activity in the peri-infarcted area will be monitored by the functional MRI after stem cell therapy The investigators study is aimed to find the potential mechanisms of the functional recovery after stem cell implantation The investigators also hope to find image surrogate markers for prediction of patient outcome The possible surrogate markers will be helpful in improving the treatment procedure and patient selection
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None